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Inverted stereocontrol of iridoid synthase in snapdragon

https://doi.org/10.1074/jbc.m117.800979

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Importance of Inherent Substrate Reactivity in Enzyme‐Promoted Carbocation Cyclization/Rearrangements

inferredcites →https://doi.org/10.1006/jmbi.1999.3235openalex-snapshot

The catalytic triad in Drosophila alcohol dehydrogenase: pH, temperature and molecular modelling studies

inferredcites →https://doi.org/10.1007/bf01259968openalex-snapshot

The iridoid glycoside, catalpol, as a deterrent to the predatorCamponotus floridanus (Formicidae)

inferredcites →https://doi.org/10.1007/s10886-007-9253-xopenalex-snapshot

The Distribution of Two Major Iridoids in Different Organs of Antirrhinum majus L. at Selected Stages of Development

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A Comparison of Antirrhinoside Distribution in the Organs of Two Related Plantaginaceae Species with Different Reproductive Strategies

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Virus induced gene silencing in Antirrhinum majus using the Cucumber mosaic virus vector: Functional analysis of the AINTEGUMENTA (Am-ANT) gene of A. majus

inferredcites →https://doi.org/10.1016/0031-9422(92)80017-9openalex-snapshot

Biosynthesis of antirrhinoside in Antirrhinum majus

inferredcites →https://doi.org/10.1016/0031-9422(92)80441-gopenalex-snapshot

Iridoid glycosides from Penstemon species: A C-5, C-9 trans iridoid and C-8 epimeric pairs

inferredcites →https://doi.org/10.1016/0031-9422(93)85027-oopenalex-snapshot

Intermediates between 8-epi-deoxyloganic acid and 6,10-dideoxyaucubin in the biosynthesis of antirrhinoside

inferredcites →https://doi.org/10.1016/0031-9422(95)00086-mopenalex-snapshot

Last stages in the biosynthesis of antirrhinoside

inferredcites →https://doi.org/10.1016/0968-0896(96)00012-0openalex-snapshot

The aphid sex pheromone cyclopentanoids: Synthesis in the elucidation of structure and biosynthetic pathways

inferredcites →https://doi.org/10.1016/j.copbio.2014.12.020openalex-snapshot

The widespread role of non-enzymatic reactions in cellular metabolism

inferredcites →https://doi.org/10.1016/j.molp.2014.11.005openalex-snapshot

Iridoid Synthase Activity Is Common among the Plant Progesterone 5β-Reductase Family

inferredcites →https://doi.org/10.1016/j.phytochem.2005.11.011openalex-snapshot

Chemotaxonomy of Veroniceae and its allies in the Plantaginaceae

inferredcites →https://doi.org/10.1016/j.phytochem.2011.04.015openalex-snapshot

Coping with toxic plant compounds – The insect’s perspective on iridoid glycosides and cardenolides

inferredcites →https://doi.org/10.1016/s0031-9422(00)81686-6openalex-snapshot

Intermediacy of 8-epiiridodial in the biosynthesis of iridoid glucosides by Gardenia jasminoides cell cultures

inferredcites →https://doi.org/10.1016/s0031-9422(00)94819-2openalex-snapshot

Biosynthesis of catalpol

inferredcites →https://doi.org/10.1016/s0031-9422(02)00102-4openalex-snapshot

Chemotaxonomy of the Oleaceae: iridoids as taxonomic markers

inferredcites →https://doi.org/10.1016/s0040-4039(00)84672-9openalex-snapshot

Synthesis of iridodial by cell free extracts from cell suspension cultures

inferredcites →https://doi.org/10.1016/s0305-1978(00)00045-4openalex-snapshot

HPLC analysis of the seasonal and diurnal variation of iridoids in cultivars of Antirrhinum majus

inferredcites →https://doi.org/10.1021/np049647dopenalex-snapshot

Simplified Isolation Procedure and Interconversion of the Diastereomers of Nepetalactone and Nepetalactol

inferredcites →https://doi.org/10.1038/nature11692openalex-snapshot

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

inferredcites →https://doi.org/10.1038/nchembio.1955openalex-snapshot

Structural determinants of reductive terpene cyclization in iridoid biosynthesis

inferredcites →https://doi.org/10.1038/ncomms4606openalex-snapshot

The seco-iridoid pathway from Catharanthus roseus

inferredcites →https://doi.org/10.1038/nprot.2008.73openalex-snapshot

Analyzing real-time PCR data by the comparative CT method

inferredcites →https://doi.org/10.1042/bst0110593openalex-snapshot

The biosynthesis of iridoid glucosides from 8-epi-deoxyloganic acid

inferredcites →https://doi.org/10.1055/s-2007-970017openalex-snapshot

8-Epi-iridodial glucoside from Boschniakia rossica

inferredcites →https://doi.org/10.1073/pnas.96.16.9159openalex-snapshot

Enzymatic activation of oleuropein: A protein crosslinker used as a chemical defense in the privet tree

inferredcites →https://doi.org/10.1074/jbc.m115.701276openalex-snapshot

Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea europaea) Fruits

inferredcites →https://doi.org/10.1079/nrr200495openalex-snapshot

The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health

inferredcites →https://doi.org/10.1093/bioinformatics/btp033openalex-snapshot

Jalview Version 2—a multiple sequence alignment editor and analysis workbench

inferredcites →https://doi.org/10.1093/nar/gkm047openalex-snapshot

A versatile ligation-independent cloning method suitable for high-throughput expression screening applications

inferredcites →https://doi.org/10.1111/j.1365-313x.2010.04184.xopenalex-snapshot

SQUAMOSA-PROMOTER BINDING PROTEIN 1 initiates flowering in Antirrhinum majus through the activation of meristem identity genes

inferredcites →https://doi.org/10.1351/pac198961030555openalex-snapshot

The aphid sex pheromone

inferredcites →https://doi.org/10.1515/znc-2017-0015openalex-snapshot

Deciphering the route to cyclic monoterpenes in Chrysomelina leaf beetles: source of new biocatalysts for industrial application?

inferredcites →https://doi.org/10.2174/092986712800229005openalex-snapshot

Anti-Inflammatory Iridoids of Botanical Origin

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112340zenodo-depositor-declared

Alterations in nepetalactone metabolism during polyethylene glycol (PEG)-induced dehydration stress in two Nepeta species

inferred← citeshttps://doi.org/10.1002/1873-3468.13174openalex-snapshot

Dynamics of loops at the substrate entry channel determine the specificity of iridoid synthases

inferred← citeshttps://doi.org/10.1002/chem.201805412openalex-snapshot

Biocatalytic Strategies towards [4+2] Cycloadditions

inferred← citeshttps://doi.org/10.1002/chem.202001356openalex-snapshot

Iridoid Sex Pheromone Biosynthesis in Aphids Mimics Iridoid‐Producing Plants

inferred← citeshttps://doi.org/10.1002/pld3.512openalex-snapshot

Transcriptome‐based identification and functional characterization of iridoid synthase involved in monotropein biosynthesis in blueberry

inferred← citeshttps://doi.org/10.1007/s00049-018-00275-9openalex-snapshot

Iridoids and volatile pheromones of Tapinoma darioi ants: chemical differences to the closely related species Tapinoma magnum

inferred← citeshttps://doi.org/10.1007/s00425-022-03824-3openalex-snapshot

Identification and functional characterization of three iridoid synthases in Gardenia jasminoides

inferred← citeshttps://doi.org/10.1007/s00425-022-04012-zopenalex-snapshot

In vivo characterization of key iridoid biosynthesis pathway genes in catnip (Nepeta cataria)

inferred← citeshttps://doi.org/10.1007/s11101-021-09774-0openalex-snapshot

Iridoid glycosides of the tribe Antirrhineae

inferred← citeshttps://doi.org/10.1007/s42994-025-00234-3openalex-snapshot

Metabolic engineering in Nicotiana benthamiana

inferred← citeshttps://doi.org/10.1007/s44281-023-00019-yopenalex-snapshot

Molecular mechanisms regulating ornamental traits and scent production in snapdragon (Antirrhinum majus L.)

inferred← citeshttps://doi.org/10.1016/j.cpb.2024.100397openalex-snapshot

Promotion of gentiopicroside production and transcriptional responses of biosynthetic genes in adventitious root cultures of Gentiana scabra Bunge by elicitation with methyl jasmonate

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.06.223openalex-snapshot

Characterization of Camptotheca acuminata 10-hydroxygeraniol oxidoreductase and iridoid synthase and their application in biological preparation of nepetalactol in Escherichia coli featuring NADP+ - NADPH cofactors recycling

inferred← citeshttps://doi.org/10.1016/j.isci.2022.104455openalex-snapshot

Domestic cat damage to plant leaves containing iridoids enhances chemical repellency to pests

inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.08.012openalex-snapshot

PRISEs (progesterone 5β-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism

inferred← citeshttps://doi.org/10.1016/j.plaphy.2025.110471openalex-snapshot

Physiology combined with metabolomics reveal selenium acting as a mitigator for Perilla frutescens (L.) Britt. growth under oxytetracycline condition: by regulating photosynthesis, redox homeostasis and secondary metabolites

inferred← citeshttps://doi.org/10.1016/j.tplants.2020.08.010openalex-snapshot

Tracking the Origin and Evolution of Plant Metabolites

inferred← citeshttps://doi.org/10.1021/acschembio.0c00220openalex-snapshot

The Progesterone 5β-Reductase/Iridoid Synthase Family: A Catalytic Reservoir for Specialized Metabolism across Land Plants

inferred← citeshttps://doi.org/10.1038/s41467-022-32414-wopenalex-snapshot

Biocatalytic routes to stereo-divergent iridoids

inferred← citeshttps://doi.org/10.1038/s41477-025-02122-6openalex-snapshot

Discovery of iridoid cyclase completes the iridoid pathway in asterids

inferred← citeshttps://doi.org/10.1038/s41589-018-0185-2openalex-snapshot

Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis

inferred← citeshttps://doi.org/10.1039/c9np00051hopenalex-snapshot

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

inferred← citeshttps://doi.org/10.1039/d5np00026bopenalex-snapshot

Biosynthesis of biologically active terpenoids in the mint family (Lamiaceae)

inferred← citeshttps://doi.org/10.1093/molbev/msac057openalex-snapshot

Phylogeny-Aware Chemoinformatic Analysis of Chemical Diversity in Lamiaceae Enables Iridoid Pathway Assembly and Discovery of Aucubin Synthase

inferred← citeshttps://doi.org/10.1093/plphys/kiad550openalex-snapshot

Citronellol biosynthesis in pelargonium is a multistep pathway involving progesterone 5β-reductase and/or iridoid synthase-like enzymes

inferred← citeshttps://doi.org/10.1111/ppl.71048openalex-snapshot

Multi‐Omics Reveal Haplotype‐Specific BGC Divergence and Organ‐Specific Iridoid Glycoside Accumulation in Endemic Species Rehmannia chingii

inferred← citeshttps://doi.org/10.1111/tpj.16698openalex-snapshot

The genomic and enzymatic basis for iridoid biosynthesis in cat thyme (Teucrium marum)

inferred← citeshttps://doi.org/10.1126/sciadv.aba0721openalex-snapshot

The evolutionary origins of the cat attractant nepetalactone in catnip

inferred← citeshttps://doi.org/10.3389/fpls.2023.1211453openalex-snapshot

Functional iridoid synthases from iridoid producing and non-producing Nepeta species (subfam. Nepetoidae, fam. Lamiaceae)

inferred← citeshttps://doi.org/10.3389/fpls.2025.1607226openalex-snapshot

The Hedyotis diffusa chromosome-level genome and multi-omics analysis provide new insights into the iridoids biosynthetic pathway

inferred← citeshttps://doi.org/10.3390/genes15020155openalex-snapshot

Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant Rehmannia glutinosa and the Functional Characterization of RgGES Genes

inferred← citeshttps://doi.org/10.70675/02a20883zee26z4f1dz84fcz2fac436faa25openalex-snapshot

Étude de la biosynthèse des terpènes et de leur régulation chez Pelargonium x hybridum

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