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DNA Polymerase λ Mediates a Back-up Base Excision Repair Activity in Extracts of Mouse Embryonic Fibroblasts

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/jmbi.2000.4005openalex-snapshot

DNA polymerase lambda (Pol λ), a novel eukaryotic DNA polymerase with a potential role in meiosis 1 1Edited by M. Yaniv

inferredcites →https://doi.org/10.1016/0753-3322(89)90130-3openalex-snapshot

Antibodies, a laboratory manual

inferredcites →https://doi.org/10.1016/s0014-5793(00)01674-4openalex-snapshot

Base excision repair of DNA in mammalian cells

inferredcites →https://doi.org/10.1016/s0021-9258(18)31783-6openalex-snapshot

Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation.

inferredcites →https://doi.org/10.1016/s0021-9258(18)34005-5openalex-snapshot

The roles of DNA polymerases alpha, beta, and gamma in DNA repair synthesis induced in hamster and human cells by different DNA damaging agents.

inferredcites →https://doi.org/10.1016/s0021-9258(19)39949-1openalex-snapshot

Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain.

inferredcites →https://doi.org/10.1016/s0021-9258(19)74229-xopenalex-snapshot

Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta.

inferredcites →https://doi.org/10.1016/s0022-2836(03)00265-1openalex-snapshot

Human DNA Polymerase λ Possesses Terminal Deoxyribonucleotidyl Transferase Activity And Can Elongate RNA Primers: Implications for Novel Functions

inferredcites →https://doi.org/10.1016/s1097-2765(04)00061-9openalex-snapshot

A Structural Solution for the DNA Polymerase λ-Dependent Repair of DNA Gaps with Minimal Homology

inferredcites →https://doi.org/10.1016/s1568-7864(02)00008-3openalex-snapshot

Involvement of DNA polymerase β in protection against the cytotoxicity of oxidative DNA damage

inferredcites →https://doi.org/10.1016/s1568-7864(02)00184-2openalex-snapshot

Hypersensitivity of DNA polymerase β null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions

inferredcites →https://doi.org/10.1021/bi00001a016openalex-snapshot

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

inferredcites →https://doi.org/10.1021/bi00403a010openalex-snapshot

Expression of human DNA polymerase .beta. in Escherichia coli and characterization of the recombinant enzyme

inferredcites →https://doi.org/10.1021/bi972999hopenalex-snapshot

Different DNA Polymerases Are Involved in the Short- and Long-Patch Base Excision Repair in Mammalian Cells

inferredcites →https://doi.org/10.1038/35015598openalex-snapshot

The lyase activity of the DNA repair protein β-polymerase protects from DNA-damage-induced cytotoxicity

inferredcites →https://doi.org/10.1038/379183a0openalex-snapshot

Requirement of mammalian DNA polymerase-β in base-excision repair

inferredcites →https://doi.org/10.1038/sj.onc.1202001openalex-snapshot

Mammalian base excision repair by DNA polymerases δ and ε

inferredcites →https://doi.org/10.1073/pnas.0308332100openalex-snapshot

Crystal structure of a benzo[ a ]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase

inferredcites →https://doi.org/10.1074/jbc.270.2.949openalex-snapshot

DNA Polymerase β Conducts the Gap-filling Step in Uracil-initiated Base Excision Repair in a Bovine Testis Nuclear Extract

inferredcites →https://doi.org/10.1074/jbc.272.2.1302openalex-snapshot

Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism

inferredcites →https://doi.org/10.1074/jbc.273.2.898openalex-snapshot

Impairment of Proliferating Cell Nuclear Antigen-dependent Apurinic/Apyrimidinic Site Repair on Linear DNA

inferredcites →https://doi.org/10.1074/jbc.273.33.21203openalex-snapshot

Mammalian Abasic Site Base Excision Repair

inferredcites →https://doi.org/10.1074/jbc.273.50.33811openalex-snapshot

Repair Pathways for Processing of 8-Oxoguanine in DNA by Mammalian Cell Extracts

inferredcites →https://doi.org/10.1074/jbc.274.21.15230openalex-snapshot

The Type of DNA Glycosylase Determines the Base Excision Repair Pathway in Mammalian Cells

inferredcites →https://doi.org/10.1074/jbc.274.33.23599openalex-snapshot

Efficient Processing of DNA Ends during Yeast Nonhomologous End Joining

inferredcites →https://doi.org/10.1074/jbc.m004263200openalex-snapshot

Identification and Characterization of Human DNA Polymerase β2, a DNA Polymerase β-Related Enzyme

inferredcites →https://doi.org/10.1074/jbc.m106336200openalex-snapshot

Identification of an Intrinsic 5′-Deoxyribose-5-phosphate Lyase Activity in Human DNA Polymerase λ

inferredcites →https://doi.org/10.1074/jbc.m111601200openalex-snapshot

DNA Polymerase λ, a Novel DNA Repair Enzyme in Human Cells

inferredcites →https://doi.org/10.1074/jbc.m200421200openalex-snapshot

DNA Polymerase λ from Calf Thymus Preferentially Replicates Damaged DNA

inferredcites →https://doi.org/10.1074/jbc.m201497200openalex-snapshot

Direct Interaction between Mammalian DNA Polymerase β and Proliferating Cell Nuclear Antigen

inferredcites →https://doi.org/10.1074/jbc.m206861200openalex-snapshot

A Physical and Functional Interaction between Yeast Pol4 and Dnl4-Lif1 Links DNA Synthesis and Ligation in Nonhomologous End Joining

inferredcites →https://doi.org/10.1074/jbc.m307913200openalex-snapshot

Implication of DNA Polymerase λ in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Human Nuclear Extracts

inferredcites →https://doi.org/10.1093/nar/14.4.1719openalex-snapshot

Differential effects of dimethylsulfoxide on the activities of human DNA polymerases α and δ

inferredcites →https://doi.org/10.1093/nar/21.23.5301openalex-snapshot

Yeast open reading frame YCR14C encodes a DNA β-polymerase-like enzyme

inferredcites →https://doi.org/10.1093/nar/24.19.3763openalex-snapshot

Characterization of the DNA polymerase requirement of human base excision repair

inferredcites →https://doi.org/10.1093/nar/28.16.3040openalex-snapshot

DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide

inferredcites →https://doi.org/10.1093/nar/28.18.3684openalex-snapshot

Two novel human and mouse DNA polymerases of the polX family

inferredcites →https://doi.org/10.1128/mcb.12.4.1605openalex-snapshot

Generation of Single-Nucleotide Repair Patches Following Excision of Uracil Residues from DNA

inferredcites →https://doi.org/10.1128/mcb.14.9.6187openalex-snapshot

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

inferredcites →https://doi.org/10.4049/jimmunol.168.8.3702openalex-snapshot

Cutting Edge: DNA Polymerases μ and λ Are Dispensable for Ig Gene Hypermutation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3155512openalex-extracted

DNA Polymerase Mediates Robust Base Lesion Repair in Mammalian Mitochondria

inferred← citeshttps://doi.org/10.1002/9780470015902.a0001045.pub2openalex-snapshot

Eukaryotic DNA Polymerases

inferred← citeshttps://doi.org/10.1002/9780470015902.a0001045.pub3openalex-snapshot

Eukaryotic DNA Polymerases

inferred← citeshttps://doi.org/10.1002/em.21725openalex-snapshot

DNA polymerases in nonhomologous end joining: Are there any benefits to standing out from the crowd?

inferred← citeshttps://doi.org/10.1002/em.21731openalex-snapshot

Mouse models of DNA polymerases

inferred← citeshttps://doi.org/10.1002/em.22593openalex-snapshot

Mouse models to explore the biological and organismic role of DNA polymerase beta

inferred← citeshttps://doi.org/10.1007/7050_007openalex-snapshot

DNA Base Damage Recognition and Processing

inferred← citeshttps://doi.org/10.1007/978-1-4614-1531-2_61openalex-snapshot

DNA Repair Polymerases

inferred← citeshttps://doi.org/10.1007/978-1-61737-995-6_14openalex-snapshot

Base-Excision Repair: Role of DNA Polymerase β in Late-Stage Base Excision Repair

inferred← citeshttps://doi.org/10.1007/978-3-642-39796-7_3openalex-snapshot

DNA Repair Polymerases

inferred← citeshttps://doi.org/10.1007/978-3-642-39796-7_5openalex-snapshot

DNA Polymerases That Perform Template-Independent DNA Synthesis

inferred← citeshttps://doi.org/10.1007/978-94-007-5237-5_2openalex-snapshot

Base Excision DNA Repair: The House Keeping Guardian for Genomic Stability in the Brain

inferred← citeshttps://doi.org/10.1007/s00018-019-03368-yopenalex-snapshot

Structure and function relationships in mammalian DNA polymerases

inferred← citeshttps://doi.org/10.1007/s11427-024-2615-1openalex-snapshot

Molecular mechanisms of DNA lesion and repair during antibody somatic hypermutation

inferred← citeshttps://doi.org/10.1016/b978-0-12-803309-8.00017-3openalex-snapshot

Base Excision Repair and Nucleotide Excision Repair

inferred← citeshttps://doi.org/10.1016/b978-0-323-85679-9.00017-9openalex-snapshot

Base excision repair and nucleotide excision repair

inferred← citeshttps://doi.org/10.1016/bs.enz.2019.08.002openalex-snapshot

DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair

inferred← citeshttps://doi.org/10.1016/j.bbapap.2005.05.012openalex-snapshot

Comparison of functional properties of mammalian DNA polymerase λ and DNA polymerase β in reactions of DNA synthesis related to DNA repair

inferred← citeshttps://doi.org/10.1016/j.bbapap.2009.07.008openalex-snapshot

DNA polymerase Family X: Function, structure, and cellular roles

inferred← citeshttps://doi.org/10.1016/j.biopha.2020.109875openalex-snapshot

The role of single strand break repair pathways in cellular responses to camptothecin induced DNA damage

inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115642openalex-snapshot

An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding

inferred← citeshttps://doi.org/10.1016/j.cbpa.2014.03.018openalex-snapshot

Looking beneath the surface to determine what makes DNA damage deleterious

inferred← citeshttps://doi.org/10.1016/j.cell.2005.10.039openalex-snapshot

Structural Analysis of Strand Misalignment during DNA Synthesis by a Human DNA Polymerase

inferred← citeshttps://doi.org/10.1016/j.dnarep.2005.09.001openalex-snapshot

Structure–function studies of DNA polymerase lambda

inferred← citeshttps://doi.org/10.1016/j.dnarep.2006.08.005openalex-snapshot

DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota

inferred← citeshttps://doi.org/10.1016/j.dnarep.2006.10.006openalex-snapshot

Mammalian single-strand break repair: Mechanisms and links with chromatin

inferred← citeshttps://doi.org/10.1016/j.dnarep.2006.10.016openalex-snapshot

Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency

inferred← citeshttps://doi.org/10.1016/j.dnarep.2007.01.011openalex-snapshot

Interplay between DNA polymerases β and λ in repair of oxidation DNA damage in chicken DT40 cells

inferred← citeshttps://doi.org/10.1016/j.dnarep.2007.03.005openalex-snapshot

Role of the catalytic metal during polymerization by DNA polymerase lambda

inferred← citeshttps://doi.org/10.1016/j.dnarep.2007.05.009openalex-snapshot

The X family portrait: Structural insights into biological functions of X family polymerases

inferred← citeshttps://doi.org/10.1016/j.dnarep.2007.09.009openalex-snapshot

Intrinsic 5′-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair

inferred← citeshttps://doi.org/10.1016/j.dnarep.2008.04.018openalex-snapshot

A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda

inferred← citeshttps://doi.org/10.1016/j.dnarep.2008.07.007openalex-snapshot

Catalytic mechanism of human DNA polymerase λ with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies

inferred← citeshttps://doi.org/10.1016/j.dnarep.2009.04.002openalex-snapshot

Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity

inferred← citeshttps://doi.org/10.1016/j.dnarep.2009.08.004openalex-snapshot

DNA polymerase β and PARP activities in base excision repair in living cells

inferred← citeshttps://doi.org/10.1016/j.dnarep.2010.03.004openalex-snapshot

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

inferred← citeshttps://doi.org/10.1016/j.dnarep.2010.09.005openalex-snapshot

Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis

inferred← citeshttps://doi.org/10.1016/j.dnarep.2012.01.002openalex-snapshot

Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair

inferred← citeshttps://doi.org/10.1016/j.dnarep.2013.09.002openalex-snapshot

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations

inferred← citeshttps://doi.org/10.1016/j.dnarep.2014.02.008openalex-snapshot

Nonhomologous end joining: A good solution for bad ends

inferred← citeshttps://doi.org/10.1016/j.dnarep.2015.02.001openalex-snapshot

DNA polymerases β and λ and their roles in cell

inferred← citeshttps://doi.org/10.1016/j.dnarep.2017.02.008openalex-snapshot

The anti / syn conformation of 8-oxo-7,8-dihydro-2′-deoxyguanosine is modulated by Bacillus subtilis PolX active site residues His255 and Asn263. Efficient processing of damaged 3′-ends

inferred← citeshttps://doi.org/10.1016/j.dnarep.2017.10.011openalex-snapshot

DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria

inferred← citeshttps://doi.org/10.1016/j.dnarep.2018.02.011openalex-snapshot

Monitoring base excision repair in Chlamydomonas reinhardtii cell extracts

inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.02.001openalex-snapshot

Deployment of DNA polymerases beta and lambda in single-nucleotide and multinucleotide pathways of mammalian base excision DNA repair

inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.102769openalex-snapshot

The splicing component ISY1 regulates APE1 in base excision repair

inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.102773openalex-snapshot

Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair

inferred← citeshttps://doi.org/10.1016/j.dnarep.2020.102921openalex-snapshot

Mammalian DNA base excision repair: Dancing in the moonlight

inferred← citeshttps://doi.org/10.1016/j.dnarep.2022.103353openalex-snapshot

Structural features of DNA polymerases β and λ in complex with benzo[a]pyrene-adducted DNA cause a difference in lesion tolerance

inferred← citeshttps://doi.org/10.1016/j.dnarep.2025.103815openalex-snapshot

The effect of methylation and hydroxymethylation of cytosine on activity and fidelity of Pol λ and Pol β

inferred← citeshttps://doi.org/10.1016/j.febslet.2011.03.069openalex-snapshot

Ubiquitylation of DNA polymerase λ

inferred← citeshttps://doi.org/10.1016/j.jmb.2007.01.069openalex-snapshot

Single-turnover Kinetic Analysis of the Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine during Gap-filling Synthesis Catalyzed by Human DNA Polymerases λ and β

inferred← citeshttps://doi.org/10.1016/j.jmb.2009.05.037openalex-snapshot

Probing Conformational Changes of Human DNA Polymerase λ using Mass Spectrometry-Based Protein Footprinting

inferred← citeshttps://doi.org/10.1016/j.jmb.2009.11.003openalex-snapshot

A Novel Mechanism of Sugar Selection Utilized by a Human X-Family DNA Polymerase

inferred← citeshttps://doi.org/10.1016/j.jmb.2010.09.014openalex-snapshot

Identification of Critical Residues for the Tight Binding of Both Correct and Incorrect Nucleotides to Human DNA Polymerase λ

inferred← citeshttps://doi.org/10.1016/j.jmb.2020.03.020openalex-snapshot

RanBP2-Mediated SUMOylation Promotes Human DNA Polymerase Lambda Nuclear Localization and DNA Repair

inferred← citeshttps://doi.org/10.1016/j.molcel.2006.07.032openalex-snapshot

Vertebrate POLQ and POLβ Cooperate in Base Excision Repair of Oxidative DNA Damage

inferred← citeshttps://doi.org/10.1016/j.molcel.2007.12.027openalex-snapshot

CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins

inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2010.01.016openalex-snapshot

Parp1 activation in mouse embryonic fibroblasts promotes Pol β-dependent cellular hypersensitivity to alkylation damage

inferred← citeshttps://doi.org/10.1016/j.mrgentox.2009.05.008openalex-snapshot

Expression of an X-family DNA polymerase, pol lambda, in the respiratory epithelium of non-small cell lung cancer patients with habitual smoking

inferred← citeshttps://doi.org/10.1016/j.mrgentox.2021.503438openalex-snapshot

Crosstalk between different DNA repair pathways for DNA double strand break repairs

inferred← citeshttps://doi.org/10.1016/j.semcancer.2010.10.010openalex-snapshot

Variant base excision repair proteins: Contributors to genomic instability

inferred← citeshttps://doi.org/10.1016/s0074-7696(06)55002-8openalex-snapshot

Roles of DNA Polymerases in Replication, Repair, and Recombination in Eukaryotes

inferred← citeshttps://doi.org/10.1021/acs.biochem.9b00087openalex-snapshot

A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β

inferred← citeshttps://doi.org/10.1021/acs.chemrestox.7b00067openalex-snapshot

Noncatalytic, N-terminal Domains of DNA Polymerase Lambda Affect Its Cellular Localization and DNA Damage Response

inferred← citeshttps://doi.org/10.1021/acs.chemrestox.7b00152openalex-snapshot

Living on the Edge: DNA Polymerase Lambda between Genome Stability and Mutagenesis

inferred← citeshttps://doi.org/10.1021/acs.jpcb.6b08581openalex-snapshot

Uniform Free-Energy Profiles of the P–O Bond Formation and Cleavage Reactions Catalyzed by DNA Polymerases β and λ

inferred← citeshttps://doi.org/10.1021/acschembio.7b00259openalex-snapshot

Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells

inferred← citeshttps://doi.org/10.1021/ar400229dopenalex-snapshot

Abasic and Oxidized Abasic Site Reactivity in DNA: Enzyme Inhibition, Cross-Linking, and Nucleosome Catalyzed Reactions

inferred← citeshttps://doi.org/10.1021/bi301592xopenalex-snapshot

DNA Polymerase λ Inactivation by Oxidized Abasic Sites

inferred← citeshttps://doi.org/10.1021/bi901792copenalex-snapshot

DNA Polymerases β and λ Bypass Thymine Glycol in Gapped DNA Structures

inferred← citeshttps://doi.org/10.1021/cr040445wopenalex-snapshot

Biochemical, Structural, and Physiological Characterization of Terminal Deoxynucleotidyl Transferase

inferred← citeshttps://doi.org/10.1021/ct3006166openalex-snapshot

Proton/Hydrogen Transfer Mechanisms in the Guanine–Cytosine Base Pair: Photostability and Tautomerism

inferred← citeshttps://doi.org/10.1021/ja1049687openalex-snapshot

DNA Pol λˈs Extraordinary Ability To Stabilize Misaligned DNA

inferred← citeshttps://doi.org/10.1021/ja411733sopenalex-snapshot

Irreversible Inhibition of DNA Polymerase β by Small-Molecule Mimics of a DNA Lesion

inferred← citeshttps://doi.org/10.1021/jacs.1c02453openalex-snapshot

Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor

inferred← citeshttps://doi.org/10.1021/jacs.5b13368openalex-snapshot

Structural Mechanism for the Fidelity Modulation of DNA Polymerase λ

inferred← citeshttps://doi.org/10.1021/jp903172xopenalex-snapshot

Relationship Between Conformational Changes in Pol λ’s Active Site Upon Binding Incorrect Nucleotides and Mismatch Incorporation Rates

inferred← citeshttps://doi.org/10.1038/cr.2008.7openalex-snapshot

XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks

inferred← citeshttps://doi.org/10.1038/embor.2008.148openalex-snapshot

Control of DNA polymerase λ stability by phosphorylation and ubiquitination during the cell cycle

inferred← citeshttps://doi.org/10.1038/nrc2998openalex-snapshot

DNA polymerases and cancer

inferred← citeshttps://doi.org/10.1038/nsmb1180openalex-snapshot

Structural insight into the substrate specificity of DNA Polymerase μ

inferred← citeshttps://doi.org/10.1038/onc.2009.378openalex-snapshot

A ‘DNA replication’ signature of progression and negative outcome in colorectal cancer

inferred← citeshttps://doi.org/10.1038/s41467-020-18506-5openalex-snapshot

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break

inferred← citeshttps://doi.org/10.1038/s41594-022-00895-4openalex-snapshot

Polλ promotes microhomology-mediated end-joining

inferred← citeshttps://doi.org/10.1038/s41598-017-07378-3openalex-snapshot

Phaeocystis globosa Virus DNA Polymerase X: a “Swiss Army knife”, Multifunctional DNA polymerase-lyase-ligase for Base Excision Repair

inferred← citeshttps://doi.org/10.1038/s41598-019-46349-8openalex-snapshot

An array of basic residues is essential for the nucleolytic activity of the PHP domain of bacterial/archaeal PolX DNA polymerases

inferred← citeshttps://doi.org/10.1038/srep27122openalex-snapshot

Nucleosomes determine their own patch size in base excision repair

inferred← citeshttps://doi.org/10.1073/pnas.0811241106openalex-snapshot

Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair

inferred← citeshttps://doi.org/10.1073/pnas.0907280106openalex-snapshot

An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ

inferred← citeshttps://doi.org/10.1073/pnas.1013603107openalex-snapshot

Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites

inferred← citeshttps://doi.org/10.1074/jbc.c500256200openalex-snapshot

DNA Polymerase λ Protects Mouse Fibroblasts against Oxidative DNA Damage and Is Recruited to Sites of DNA Damage/Repair

inferred← citeshttps://doi.org/10.1074/jbc.m109.094391openalex-snapshot

Interaction between DNA Polymerase λ and Anticancer Nucleoside Analogs

inferred← citeshttps://doi.org/10.1074/jbc.m117.793661openalex-snapshot

A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells

inferred← citeshttps://doi.org/10.1074/jbc.m117.801860openalex-snapshot

Processive searching ability varies among members of the gap-filling DNA polymerase X family

inferred← citeshttps://doi.org/10.1074/jbc.m501981200openalex-snapshot

Biochemical Properties of Saccharomyces cerevisiae DNA Polymerase IV

inferred← citeshttps://doi.org/10.1074/jbc.m601178200openalex-snapshot

Up-regulation of the Fidelity of Human DNA Polymerase λ by Its Non-enzymatic Proline-rich Domain

inferred← citeshttps://doi.org/10.1080/07352680701252817openalex-snapshot

Multiple Functions of DNA Polymerases

inferred← citeshttps://doi.org/10.1084/jem.20070756openalex-snapshot

DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination

inferred← citeshttps://doi.org/10.1089/ars.2010.3429openalex-snapshot

Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes

inferred← citeshttps://doi.org/10.1093/carcin/bgq166openalex-snapshot

The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway

inferred← citeshttps://doi.org/10.1093/mutage/gel020openalex-snapshot

Base excision repair fidelity in normal and cancer cells

inferred← citeshttps://doi.org/10.1093/nar/gkaa140openalex-snapshot

Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation

inferred← citeshttps://doi.org/10.1093/nar/gkag114openalex-snapshot

DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining

inferred← citeshttps://doi.org/10.1093/nar/gki780openalex-snapshot

Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe

inferred← citeshttps://doi.org/10.1093/nar/gki845openalex-snapshot

Phosphorylation of human DNA polymerase by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen

inferred← citeshttps://doi.org/10.1093/nar/gkl032openalex-snapshot

Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase

inferred← citeshttps://doi.org/10.1093/nar/gkn526openalex-snapshot

Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase

inferred← citeshttps://doi.org/10.1093/nar/gkq261openalex-snapshot

Loop 1 modulates the fidelity of DNA polymerase

inferred← citeshttps://doi.org/10.1093/nar/gkr727openalex-snapshot

Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase

inferred← citeshttps://doi.org/10.1093/nar/gks648openalex-snapshot

Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage

inferred← citeshttps://doi.org/10.1093/nar/gks702openalex-snapshot

DNA stabilization at the Bacillus subtilis PolX core —a binding model to coordinate polymerase, AP-endonuclease and 3′-5′ exonuclease activities

inferred← citeshttps://doi.org/10.1101/2025.05.12.25325832openalex-snapshot

Comprehensive investigation of DNA damage repair genes in children with cancer identifies SMARCAL1 as novel osteosarcoma predisposition gene

inferred← citeshttps://doi.org/10.1105/tpc.105.038000openalex-snapshot

Rapid Changes in Plant Genomes

inferred← citeshttps://doi.org/10.1111/j.1365-313x.2009.03994.xopenalex-snapshot

Single‐nucleotide and long‐patch base excision repair of DNA damage in plants

inferred← citeshttps://doi.org/10.1111/j.1471-4159.2008.05644.xopenalex-snapshot

DNA polymerase β‐catalyzed‐PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post‐mitotic brain

inferred← citeshttps://doi.org/10.1111/j.1742-4658.2006.05192.xopenalex-snapshot

Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA

inferred← citeshttps://doi.org/10.1134/s0006297908090125openalex-snapshot

Interaction between DNA polymerase λ and RPA during translesion synthesis

inferred← citeshttps://doi.org/10.1134/s0006297908110060openalex-snapshot

DNA polymerases β and λ as potential participants of TLS during genomic DNA replication on the lagging strand

inferred← citeshttps://doi.org/10.1134/s000629792560293xopenalex-snapshot

Regulation of Activity of DNA Polymerases β and λ by XRCC1, PARP1, and PARP2 Proteins

inferred← citeshttps://doi.org/10.1134/s0026893310060014openalex-snapshot

DNA polymerases β and λ and their roles in DNA replication and repair

inferred← citeshttps://doi.org/10.1146/annurev-biochem-013118-111315openalex-snapshot

Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism

inferred← citeshttps://doi.org/10.1146/annurev.genet.39.073003.113340openalex-snapshot

Nonhomologous End Joining in Yeast

inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-16-0209openalex-snapshot

Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer–Associated R438W DNA Polymerase Lambda Protein

inferred← citeshttps://doi.org/10.1186/2041-9414-3-10openalex-snapshot

Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

inferred← citeshttps://doi.org/10.1186/s12929-018-0470-0openalex-snapshot

Ubiquitination by HUWE1 in tumorigenesis and beyond

inferred← citeshttps://doi.org/10.1371/journal.pone.0007290openalex-snapshot

Characterization of a Natural Mutator Variant of Human DNA Polymerase λ which Promotes Chromosomal Instability by Compromising NHEJ

inferred← citeshttps://doi.org/10.1371/journal.pone.0012229openalex-snapshot

DNA Polymerases β and λ Mediate Overlapping and Independent Roles in Base Excision Repair in Mouse Embryonic Fibroblasts

inferred← citeshttps://doi.org/10.1371/journal.pone.0022224openalex-snapshot

Production of Recombinant Human DNA Polymerase Delta in a Bombyx mori Bioreactor

inferred← citeshttps://doi.org/10.1371/journal.pone.0068576openalex-snapshot

Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System

inferred← citeshttps://doi.org/10.1371/journal.pone.0223725openalex-snapshot

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer

inferred← citeshttps://doi.org/10.1667/rr1057r.1openalex-snapshot

Ionizing Radiation Sensitivity of DNA Polymerase Lambda-Deficient Cells

inferred← citeshttps://doi.org/10.2174/1874467211205010003openalex-snapshot

Overview of Base Excision Repair Biochemistry

inferred← citeshttps://doi.org/10.26508/lsa.202000900openalex-snapshot

A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ

inferred← citeshttps://doi.org/10.3389/fchem.2019.00536openalex-snapshot

The Role of Proton Transfer on Mutations

inferred← citeshttps://doi.org/10.3389/fcimb.2021.670564openalex-snapshot

Molecular and Functional Characteristics of DNA Polymerase Beta-Like Enzymes From Trypanosomatids

inferred← citeshttps://doi.org/10.3389/fimmu.2020.01084openalex-snapshot

Base Excision Repair in the Immune System: Small DNA Lesions With Big Consequences

inferred← citeshttps://doi.org/10.3389/fpls.2015.00357openalex-snapshot

Arabidopsis DNA polymerase lambda mutant is mildly sensitive to DNA double strand breaks but defective in integration of a transgene

inferred← citeshttps://doi.org/10.3390/genes13010015openalex-snapshot

Structural Insights into the Specificity of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Family X DNA Polymerases

inferred← citeshttps://doi.org/10.3390/ijms25136927openalex-snapshot

DNA Repair Protein XRCC1 Stimulates Activity of DNA Polymerase λ under Conditions of Microphase Separation

inferred← citeshttps://doi.org/10.5772/53908openalex-snapshot

Evolving DNA Repair Polymerases: From Double—Strand Break Repair to Base Excision Repair and VDJ Recombination

inferred← citeshttps://doi.org/10.70675/a794a7dfz4352z46f0zb97az064f9ea78e46openalex-snapshot

Functional genomics characterization of genetic predisposing factors in uveal melanoma

inferred← citeshttps://doi.org/10.7124/bc.000051openalex-snapshot

Study of the activity of DNA polymerases β and λ using 5-formyluridine containing DNA substrates

inferred← citeshttps://doi.org/10.7243/2052-6199-2-3openalex-snapshot

Methylation of DNA repair genes and the efficacy of DNA targeted anticancer treatment

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