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Matrix Biology of Abdominal Aortic Aneurysms in Diabetes: Mechanisms Underlying the Negative Association

https://doi.org/10.1080/03008200701331524

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Genotype–phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion

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Decreased Contraction of Glycated Collagen Lattices Coincides with Impaired Matrix Metalloproteinase Production

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Interactions of elastin and aorta with sugars in vitro and their effects on biochemical and physical properties

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Monocytic expression of CD14 and CD18, circulating adhesion molecules and inflammatory markers in women with diabetes mellitus and impaired glucose tolerance

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Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM

inferredcites →https://doi.org/10.1007/s001250051353openalex-snapshot

High glucose concentration inhibits the expression of membrane type metalloproteinase by mesangial cells: possible role in mesangium accumulation

inferredcites →https://doi.org/10.1007/s001250051640openalex-snapshot

Glycation cross-links inhibit matrix metalloproteinase-2 activation in vascular smooth muscle cells cultured on collagen lattice

inferredcites →https://doi.org/10.1007/s00508-005-0425-9openalex-snapshot

PAI-1 4G/5G insertion/deletion promoter polymorphism and microvascular complications in type 2 diabetes mellitus

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Advanced glycation end products and vascular structure and function

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Advanced glycation end-product cross-link breakersA novel approach to cardiovascular pathologies related to the aging process

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Statins are Associated with a Reduced Infrarenal Abdominal Aortic Aneurysm Growth

inferredcites →https://doi.org/10.1016/j.ejvs.2006.11.011openalex-snapshot

Reduced Aortic Wall Stress in Diabetes Mellitus

inferredcites →https://doi.org/10.1016/j.ejvs.2006.12.017openalex-snapshot

Negative Association between Infra-renal Aortic Diameter and Glycaemia: The Health In Men Study

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Age-related changes in the glycation of human aortic elastin

inferredcites →https://doi.org/10.1016/s0021-9150(03)00140-0openalex-snapshot

High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes

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Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study

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Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm

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Racial differences in the incidence of femoral bypass and abdominal aortic aneurysmectomy in Massachusetts: Relationship to cardiovascular risk factors

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Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms

inferredcites →https://doi.org/10.1016/s0950-821x(05)80708-xopenalex-snapshot

Modifications of the extracellular matrix of aneurysmal abdominal aortas as a function of their size

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Compliance and diameter in the human abdominal aorta—The influence of age and sex

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Structural-functional correlations of diabetic nephropathy

inferredcites →https://doi.org/10.1038/ng1732openalex-snapshot

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

inferredcites →https://doi.org/10.1046/j.1464-5491.1999.00174.xopenalex-snapshot

High glucose increases growth and collagen synthesis in cultured human tubulointerstitial cells

inferredcites →https://doi.org/10.1046/j.1523-1755.2000.07713.xopenalex-snapshot

Effects of glucose on matrix metalloproteinase and plasmin activities in mesangial cells: Possible role in diabetic nephropathy

inferredcites →https://doi.org/10.1046/j.1523-1755.2003.00824.xopenalex-snapshot

Glucose-induced fibronectin and collagen type III expression in renal fibroblasts can occur independent of TGF-β1

inferredcites →https://doi.org/10.1053/ejvs.2000.1210openalex-snapshot

Abdominal Aortic Aneurysm and Aortic Occlusive Disease: a Comparison of Risk Factors and Inflammatory Response

inferredcites →https://doi.org/10.1053/ejvs.2002.1857openalex-snapshot

Overexpression of transforming growth factor β1 in smooth muscle cells of human abdominal aortic aneurysm

inferredcites →https://doi.org/10.1053/ejvs.2002.1874openalex-snapshot

Genetic linkage of candidate genes in families with abdominal aortic aneurysms?

inferredcites →https://doi.org/10.1055/s-0037-1616230openalex-snapshot

Plasmin and Matrix Metalloproteinases in Vascular Remodeling

inferredcites →https://doi.org/10.1056/nejm199311113292004openalex-snapshot

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy

inferredcites →https://doi.org/10.1067/mlc.2001.115494openalex-snapshot

Advanced glycosylation end products stimulate collagen mRNA synthesis in mesangial cells mediated by protein kinase C and transforming growth factor–beta

inferredcites →https://doi.org/10.1067/mva.2000.104589openalex-snapshot

Association of the 4G/5G polymorphism in the promoter region of plasminogen activator inhibitor-1 with abdominal aortic aneurysms

inferredcites →https://doi.org/10.1067/mva.2001.112810openalex-snapshot

Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors

inferredcites →https://doi.org/10.1067/mva.2001.119040openalex-snapshot

Plasma levels of plasmin-antiplasmin-complexes are predictive for small abdominal aortic aneurysms expanding to operation-recommendable sizes

inferredcites →https://doi.org/10.1067/mva.2001.119401openalex-snapshot

MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen

inferredcites →https://doi.org/10.1074/jbc.274.9.5830openalex-snapshot

Suppression Subtractive Hybridization Identifies High Glucose Levels as a Stimulus for Expression of Connective Tissue Growth Factor and Other Genes in Human Mesangial Cells

inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a010245openalex-snapshot

Risk Factors for Abdominal Aortic Aneurysm: Results of a Case-Control Study

inferredcites →https://doi.org/10.1093/oxfordjournals.epirev.a017997openalex-snapshot

Epidemiology of Abdominal Aortic Aneurysms

inferredcites →https://doi.org/10.1097/00004872-200301000-00002openalex-snapshot

Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes

inferredcites →https://doi.org/10.1097/01.mnh.0000214768.21911.62openalex-snapshot

Managing diabetic nephropathy: recent studies

inferredcites →https://doi.org/10.1113/expphysiol.2005.030130openalex-snapshot

New aspects of vascular remodelling: the involvement of all vascular cell types

inferredcites →https://doi.org/10.1136/bmj.38793.468449.aeopenalex-snapshot

Efficacy of lipid lowering drug treatment for diabetic and non-diabetic patients: metaanalysis of randomised controlled trials

inferredcites →https://doi.org/10.1136/bmj.38953.598947.80openalex-snapshot

Predictive genetic testing for type 2 diabetes

inferredcites →https://doi.org/10.1152/ajpheart.00340.2004openalex-snapshot

Profibrotic influence of high glucose concentration on cardiac fibroblast functions: effects of losartan and vitamin E

inferredcites →https://doi.org/10.1152/ajprenal.00210.2006openalex-snapshot

Glibenclamide prevents increased extracellular matrix formation induced by high glucose concentration in mesangial cells

inferredcites →https://doi.org/10.1159/000064470openalex-snapshot

The Decorin Gene 179 Allelic Variant Is Associated with a Slower Progression of Renal Disease in Patients with Type 1 Diabetes

inferredcites →https://doi.org/10.1159/000147926openalex-snapshot

Altered Kidney Matrix Gene Expression in Early Stages of Experimental Diabetes

inferredcites →https://doi.org/10.1159/000173864openalex-snapshot

Abnormal Gene Expression of Matrix Metalloproteinases and Their Inhibitor in Glomeruli from Diabetic Rats

inferredcites →https://doi.org/10.1161/01.atv.0000094235.78783.d1openalex-snapshot

Role of Angiotensin II in Altered Expression of Molecules Responsible for Coronary Matrix Remodeling in Insulin-Resistant Diabetic Rats

inferredcites →https://doi.org/10.1161/01.atv.0000131783.74034.97openalex-snapshot

Morphologic Findings of Coronary Atherosclerotic Plaques in Diabetics

inferredcites →https://doi.org/10.1161/01.atv.0000214999.12921.4fopenalex-snapshot

Inflammation and Cellular Immune Responses in Abdominal Aortic Aneurysms

inferredcites →https://doi.org/10.1161/01.atv.15.8.1145openalex-snapshot

Inflammation and Matrix Metalloproteinases in the Enlarging Abdominal Aortic Aneurysm

inferredcites →https://doi.org/10.1161/01.atv.18.3.432openalex-snapshot

Extracellular Matrix Modulates Macrophage Functions Characteristic to Atheroma

inferredcites →https://doi.org/10.1161/01.atv.19.3.562openalex-snapshot

Relative Contribution of Insulin and Its Precursors to Fibrinogen and PAI-1 in a Large Population With Different States of Glucose Tolerance

inferredcites →https://doi.org/10.1161/01.cir.0000086014.80477.0dopenalex-snapshot

The Receptor RAGE as a Progression Factor Amplifying Arachidonate-Dependent Inflammatory and Proteolytic Response in Human Atherosclerotic Plaques

inferredcites →https://doi.org/10.1161/01.cir.0000133279.07468.9fopenalex-snapshot

Abdominal Aortic Aneurysm Expansion

inferredcites →https://doi.org/10.1161/01.cir.0000138746.14425.00openalex-snapshot

C-Reactive Protein Levels and the Expansion of Screen-Detected Abdominal Aortic Aneurysms in Men

inferredcites →https://doi.org/10.1161/01.cir.103.18.2222openalex-snapshot

On Genetics, Inflammation, and Abdominal Aortic Aneurysm

inferredcites →https://doi.org/10.1161/01.cir.104.3.304openalex-snapshot

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

inferredcites →https://doi.org/10.1161/01.cir.96.7.2228openalex-snapshot

Size Matters

inferredcites →https://doi.org/10.1161/01.cir.98.3.249openalex-snapshot

Prevention of Aneurysm Development and Rupture by Local Overexpression of Plasminogen Activator Inhibitor-1

inferredcites →https://doi.org/10.1161/01.hyp.0000111829.46090.92openalex-snapshot

Increased Central Artery Stiffness in Impaired Glucose Metabolism and Type 2 Diabetes

inferredcites →https://doi.org/10.1161/01.hyp.0000153308.91043.97openalex-snapshot

Effect of Treatment With Candesartan or Enalapril on Subcutaneous Small Artery Structure in Hypertensive Patients With Noninsulin-Dependent Diabetes Mellitus

inferredcites →https://doi.org/10.1161/01.res.0000061571.49375.e1openalex-snapshot

Urokinase-Type Plasminogen Activator Plays a Critical Role in Angiotensin II–Induced Abdominal Aortic Aneurysm

inferredcites →https://doi.org/10.1161/01.res.86.9.998openalex-snapshot

Allele-Specific Regulation of Matrix Metalloproteinase-12 Gene Activity Is Associated With Coronary Artery Luminal Dimensions in Diabetic Patients With Manifest Coronary Artery Disease

inferredcites →https://doi.org/10.1161/hc0402.102621openalex-snapshot

Stromelysin-1 (Matrix Metalloproteinase-3) and Tissue Inhibitor of Metalloproteinase-3 Are Overexpressed in the Wall of Abdominal Aortic Aneurysms

inferredcites →https://doi.org/10.1161/hh1201.092042openalex-snapshot

Diabetes Mellitus Enhances Vascular Matrix Metalloproteinase Activity

inferredcites →https://doi.org/10.1172/jci0215334openalex-snapshot

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

inferredcites →https://doi.org/10.1172/jci118037openalex-snapshot

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

inferredcites →https://doi.org/10.1172/jci15334openalex-snapshot

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

inferredcites →https://doi.org/10.1172/jci2182openalex-snapshot

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms.

inferredcites →https://doi.org/10.1172/jci7818openalex-snapshot

Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E–deficient mice

inferredcites →https://doi.org/10.1172/jci8931openalex-snapshot

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

inferredcites →https://doi.org/10.1196/annals.1333.088openalex-snapshot

Advanced Glycation End Products in Diabetes‐Associated Atherosclerosis and Renal Disease: Interventional Studies

inferredcites →https://doi.org/10.1196/annals.1383.025openalex-snapshot

Abdominal Aortic Aneurysm as a Complex Multifactorial Disease

inferredcites →https://doi.org/10.1210/en.142.5.1760openalex-snapshot

Advanced Glycosylation End Products Up-Regulate Connective Tissue Growth Factor (Insulin-Like Growth Factor-Binding Protein-Related Protein 2) in Human Fibroblasts: A Potential Mechanism for Expansion of Extracellular Matrix in Diabetes Mellitus

inferredcites →https://doi.org/10.1210/en.2004-0436openalex-snapshot

Connective Tissue Growth Factor Mediates High Glucose Effects on Matrix Degradation through Tissue Inhibitor of Matrix Metalloproteinase Type 1: Implications for Diabetic Nephropathy

inferredcites →https://doi.org/10.1210/en.2006-0686openalex-snapshot

Potential Antiinflammatory Role of Insulin via the Preferential Polarization of Effector T Cells toward a T Helper 2 Phenotype

inferredcites →https://doi.org/10.2174/1566524053766095openalex-snapshot

Type 2 Diabetes As An Inflammatory Cardiovascular Disorder

inferredcites →https://doi.org/10.2337/diabetes.48.10.2066openalex-snapshot

Role of angiotensin II in glucose-induced inhibition of mesangial matrix degradation.

inferredcites →https://doi.org/10.2337/diabetes.51.10.3063openalex-snapshot

Evidence for a Matrix Metalloproteinase Induction/Activation System in Arterial Vasculature and Decreased Synthesis and Activity in Diabetes

inferredcites →https://doi.org/10.2337/diabetes.54.4.1171openalex-snapshot

Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy

inferredcites →https://doi.org/10.2337/diabetes.55.03.06.db05-0832openalex-snapshot

The Ubiquitin-Proteasome System and Inflammatory Activity in Diabetic Atherosclerotic Plaques

inferredcites →https://doi.org/10.2353/ajpath.2006.050868openalex-snapshot

Renewal of Mural Thrombus Releases Plasma Markers and Is Involved in Aortic Abdominal Aneurysm Evolution

inferredcites →https://doi.org/10.3109/15419069609010765openalex-snapshot

Effect of Matrix Glycation on Expression of Type IV Collagen, MMP-2, MMP-9 and TIMP-1 by Human

inferredcites →https://doi.org/10.5694/j.1326-5377.1997.tb123296.xopenalex-snapshot

Prevalence of abdominal aortic aneurysms in men with diabetes

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Screening for abdominal aortic aneurysm: lessons from a population‐based study

inferredcites →https://doi.org/10.7326/0003-4819-126-6-199703150-00004openalex-snapshot

Prevalence and Associations of Abdominal Aortic Aneurysm Detected through Screening

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Paradoxical Associations of Diabetes and Obesity with Abdominal Aortic Aneurysm

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Advanced complicated diabetes mellitus is associated with a reduced risk of thoracic and abdominal aortic aneurysm rupture: a population‐based cohort study

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Medikamentöse Therapie zur Risikoreduktion und Progressionshemmung nicht interventionspflichtiger abdomineller Aortenaneurysmen

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Die Pathophysiologie des abdominalen Aortenaneurysmas

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Epigenetics and Peripheral Artery Disease

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Association Between Cardiovascular Risk Factors and the Diameter of the Thoracic Aorta in an Asymptomatic Population in the Central Appalachian Region

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Diabetes mellitus as a protective factor of abdominal aortic aneurysm: Possible mechanisms

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La diabetes mellitus como factor protector del aneurisma de aorta abdominal: posibles mecanismos

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Socioeconomic Position, Comorbidity, and Mortality in Aortic Aneurysms: A 13-Year Prospective Cohort Study

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The Protective Effects of Diabetes Mellitus on Post-EVAR AAA Growth and Reinterventions

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Animal models of abdominal aortic aneurysm and their role in furthering management of human disease

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Diabetes is not protective against the formation of unruptured cerebral aneurysm

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Diabetes and the Abdominal Aortic Aneurysm

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Diabetes and Abdominal Aortic Aneurysms

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Something Sweet from Uncontrolled Sugar: The Enduring Protection of Impaired Glucose Control on Abdominal Aortic Aneurysm Risk

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4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts

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Systematic review and Meta-Analysis of Mendelian randomisation analyses of Abdominal aortic aneurysms

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Diabetes mellitus and the risk of abdominal aortic aneurysm: A systematic review and meta-analysis of prospective studies

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Cardiovascular risk profile and outcome of patients with abdominal aortic aneurysm in out-patients with atherothrombosis: Data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry

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Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study

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Aneurysmal disease is associated with lower carotid intima-media thickness than occlusive arterial disease

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Abdominal Aortic Aneurysm: Evolving Controversies and Uncertainties

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The Association Between Abdominal Aortic Aneurysms With Cardiovascular and Noncardiovascular Diseases

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Diabetes Mellitus and Noncardiac Atherosclerotic Vascular Disease—Pathogenesis and Pharmacological Treatment Options

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inferred← citeshttps://doi.org/10.1177/23969873241274547openalex-snapshot

Atherosclerosis in patients with cervical artery dissection

inferred← citeshttps://doi.org/10.1186/s12902-022-01008-4openalex-snapshot

Clinical features and prognosis of patients with and without diabetes mellitus undergoing endovascular aortic aneurysm repair

inferred← citeshttps://doi.org/10.1186/s12933-014-0147-2openalex-snapshot

Association of impaired fasting glucose, diabetes and their management with the presentation and outcome of peripheral artery disease: a cohort study

inferred← citeshttps://doi.org/10.1371/journal.pone.0022632openalex-snapshot

Neuropsychiatric Symptoms in Patients with Aortic Aneurysms

inferred← citeshttps://doi.org/10.1371/journal.pone.0083855openalex-snapshot

Hospitalization Rates and Post-Operative Mortality for Abdominal Aortic Aneurysm in Italy over the Period 2000–2011

inferred← citeshttps://doi.org/10.1371/journal.pone.0164015openalex-snapshot

Chronic Kidney Disease Is Positively and Diabetes Mellitus Is Negatively Associated with Abdominal Aortic Aneurysm

inferred← citeshttps://doi.org/10.1586/erc.09.56openalex-snapshot

Pharmacological therapy for patients with abdominal aortic aneurysm

inferred← citeshttps://doi.org/10.2174/1570161116666180828155622openalex-snapshot

Diabetes, Incretin Therapy and Thoracic Aortic Aneurysm – What Does the Evidence Show?

inferred← citeshttps://doi.org/10.2217/17455057.5.1.33openalex-snapshot

Identifying Abdominal Aortic Aneurysm Risk Factors in Postmenopausal Women

inferred← citeshttps://doi.org/10.2337/db17-0134openalex-snapshot

Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1)

inferred← citeshttps://doi.org/10.23736/s0392-9590.20.04362-xopenalex-snapshot

Abdominal aortic aneurysm: a review on the role of oral antidiabetic drugs

inferred← citeshttps://doi.org/10.33612/diss.134374625openalex-snapshot

Overview of one decade developments of an EVAR endograft

inferred← citeshttps://doi.org/10.3389/fcvm.2021.769343openalex-snapshot

Exploring the Correlation and Protective Role of Diabetes Mellitus in Aortic Aneurysm Disease

inferred← citeshttps://doi.org/10.3389/fcvm.2025.1683361openalex-snapshot

Prognostic value of diabetes mellitus for acute type B intramural hematoma patients undergoing endovascular repair

inferred← citeshttps://doi.org/10.3390/designs6010005openalex-snapshot

Photocrosslinking of Adventitial Collagen in the Porcine Abdominal Aorta: A Preliminary Approach to a Strategy for Prevention of Aneurysmal Rupture

inferred← citeshttps://doi.org/10.3390/jcm13123551openalex-snapshot

Endovascular Treatment of Abdominal Aortic Aneurysm: Impact of Diabetes on Endoleaks and Reintervention

inferred← citeshttps://doi.org/10.5603/aa.2019.0001openalex-snapshot

Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland

inferred← citeshttps://doi.org/10.5603/chsin.2019.0038openalex-snapshot

Czynniki charakterystyczne dla tętniaka aorty brzusznej i jego potencjalne biomarkery

inferred← citeshttps://doi.org/10.6084/m9.figshare.19549847openalex-snapshot

Additional file 1 of Clinical features and prognosis of patients with and without diabetes mellitus undergoing endovascular aortic aneurysm repair

inferred← citeshttps://doi.org/10.70675/aa4fb2f8ze6c0z4064z80b0z6ebe02bea928openalex-snapshot

Développement de l'imagerie moléculaire du thrombus artériel

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