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Cinnamic acid derivatives: inhibitory activity against Escherichia coli β -glucuronidase and structure–activity relationships

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00253-018-9285-xopenalex-snapshot
Characteristics and molecular determinants of a highly selective and efficient glycyrrhizin-hydrolyzing β-glucuronidase from Staphylococcus pasteuri 3I10
inferredcites →https://doi.org/10.1007/s10822-014-9745-zopenalex-snapshot
Structure-based design, synthesis and biological evaluation of β-glucuronidase inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2015.04.081openalex-snapshot
Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: A new class of β-glucuronidase inhibitors and in silico studies
inferredcites →https://doi.org/10.1016/j.bmc.2015.10.037openalex-snapshot
Synthesis of novel benzohydrazone–oxadiazole hybrids as β-glucuronidase inhibitors and molecular modeling studies
inferredcites →https://doi.org/10.1016/j.bmc.2016.03.020openalex-snapshot
Thiadiazole derivatives as New Class of β-glucuronidase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2018.11.056openalex-snapshot
Practical one-step glucuronidation via biotransformation
inferredcites →https://doi.org/10.1016/j.bse.2004.05.011openalex-snapshot
Antioxidant phenylethanoid glycosides from the rhizomes of Eremostachys glabra (Lamiaceae)
inferredcites →https://doi.org/10.1016/j.cell.2014.03.011openalex-snapshot
Role of the Microbiota in Immunity and Inflammation
inferredcites →https://doi.org/10.1016/j.chembiol.2015.08.005openalex-snapshot
Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity
inferredcites →https://doi.org/10.1016/j.fct.2016.02.007openalex-snapshot
Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases
inferredcites →https://doi.org/10.1016/j.fct.2017.03.042openalex-snapshot
Structure-activity relationships of flavonoids as natural inhibitors against E. coli β-glucuronidase
inferredcites →https://doi.org/10.1016/j.foodres.2017.06.025openalex-snapshot
Profiling hydroxycinnamic acid glycosides, iridoid glycosides, and phenylethanoid glycosides in baobab fruit pulp (Adansonia digitata)
inferredcites →https://doi.org/10.1016/j.ijbiomac.2019.12.057openalex-snapshot
The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase
inferredcites →https://doi.org/10.1016/j.jff.2018.07.013openalex-snapshot
Prenylflavonoids sanggenon C and kuwanon G from mulberry (Morus alba L.) as potent broad-spectrum bacterial β-glucuronidase inhibitors: Biological evaluation and molecular docking studies
inferredcites →https://doi.org/10.1016/j.taap.2016.04.009openalex-snapshot
Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases
inferredcites →https://doi.org/10.1016/s0378-8741(00)00189-6openalex-snapshot
Antioxidant activity of phenylethanoid glycosides from Brandisia hancei
inferredcites →https://doi.org/10.1038/mp.2016.50openalex-snapshot
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
inferredcites →https://doi.org/10.1038/s41598-018-36069-wopenalex-snapshot
Structure, function, and inhibition of drug reactivating human gut microbial β-glucuronidases
inferredcites →https://doi.org/10.1039/c7ra03521gopenalex-snapshot
Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample preparation and LC-MS/MS
inferredcites →https://doi.org/10.1073/pnas.1716241115openalex-snapshot
Structural basis for the regulation of β-glucuronidase expression by human gut Enterobacteriaceae
inferredcites →https://doi.org/10.1124/jpet.111.191122openalex-snapshot
Pharmacologic Targeting of Bacterial β-Glucuronidase Alleviates Nonsteroidal Anti-Inflammatory Drug-Induced Enteropathy in Mice
inferredcites →https://doi.org/10.1126/science.1191175openalex-snapshot
Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
inferredcites →https://doi.org/10.1155/2018/9734845openalex-snapshot
Phytochemicals That Influence Gut Microbiota as Prophylactics and for the Treatment of Obesity and Inflammatory Diseases
inferredcites →https://doi.org/10.1177/2472555217725264openalex-snapshot
Amoxapine Demonstrates Incomplete Inhibition of β-Glucuronidase Activity from Human Gut Microbiota
inferredcites →https://doi.org/10.1254/jjp.75.407openalex-snapshot
Preventive Effects of Hange-shashin-to on Irinotecan Hydrochloride-Caused Diarrhea and Its Relevance to the Colonic Prostaglandin E2 and Water Absorption in the Rat
inferredcites →https://doi.org/10.18433/jpps29783openalex-snapshot
Inhibitory Effects of Baicalein Derived from Japanese Traditional Herbal Medicine on SN-38 Glucuronidation
inferredcites →https://doi.org/10.3109/00498254.2013.811314openalex-snapshot
Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics
inferredcites →https://doi.org/10.3389/fphar.2019.00182openalex-snapshot
Herbal Medicines for Irinotecan-Induced Diarrhea
inferredcites →https://doi.org/10.3389/fphys.2019.00428openalex-snapshot
The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release
inferredcites →https://doi.org/10.3390/foods8100440openalex-snapshot
Targeting Gut Microbiota for the Prevention and Management of Diabetes Mellitus by Dietary Natural Products
inferredcites →https://doi.org/10.3390/molecules22081247openalex-snapshot
Multifunctional Cinnamic Acid Derivatives

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4827456openalex-extracted
inferred← citeshttps://doi.org/10.1002/cnr2.70315openalex-snapshot
Flavonoids as Promising Akt1 Inhibitors in Cancer Medicine: Insights From Molecular Docking, Dynamics, DFT Calculations, and In Vitro Validation
inferred← citeshttps://doi.org/10.1007/978-981-96-1305-2_16openalex-snapshot
Human Microbiota and Metabolic Alteration in Cancer Progression and Treatment
inferred← citeshttps://doi.org/10.1007/s10565-024-09922-0openalex-snapshot
Three bioactive compounds from Huangqin decoction ameliorate Irinotecan-induced diarrhea via dual-targeting of Escherichia coli and bacterial β-glucuronidase
inferred← citeshttps://doi.org/10.1007/s12272-026-01616-xopenalex-snapshot
Cinnamic acid attenuates Klebsiella pneumoniae virulence by suppressing capsule biosynthesis
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105306openalex-snapshot
Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109453openalex-snapshot
Amentoflavone from Selaginella tamariscina as a potent inhibitor of gut bacterial β-glucuronidase: Inhibition kinetics and molecular dynamics stimulation
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113322openalex-snapshot
2,5-Disubstituted furan derivatives containing 1,3,4-thiadiazole moiety as potent α-glucosidase and E. coli β-glucuronidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114699openalex-snapshot
Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches
inferred← citeshttps://doi.org/10.1016/j.fochx.2026.103637openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153770openalex-snapshot
Syringa microphylla Diels: A comprehensive review of its phytochemical, pharmacological, pharmacokinetic, and toxicological characteristics and an investigation into its potential health benefits
inferred← citeshttps://doi.org/10.1080/14756366.2020.1816998openalex-snapshot
Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships
inferred← citeshttps://doi.org/10.1080/14756366.2024.2387415openalex-snapshot
Design, synthesis, and biological evaluation of (thio)urea derivatives as potent Escherichia coli β -glucuronidase inhibitors
inferred← citeshttps://doi.org/10.1080/14756366.2025.2596488openalex-snapshot
Advancing infection therapy: the role of novel menthol-based antimicrobials
inferred← citeshttps://doi.org/10.1093/jat/bkab090openalex-snapshot
Factors Compromising Glucuronidase Performance in Urine Drug Testing Potentially Resulting in False Negatives
inferred← citeshttps://doi.org/10.26599/fmh.2026.9420139openalex-snapshot
Targeting Gut Microbiota-derived β-glucuronidase to Reduce Enterotoxicity: Research Progress on Strategies and Prospects for the Application of Food and Medicine Homology
inferred← citeshttps://doi.org/10.3136/fstr.27.797openalex-snapshot
Inhibitory effect of 4-ethylcatechol on β-glucuronidase activity
inferred← citeshttps://doi.org/10.3389/fcell.2021.631552openalex-snapshot
The Role of Gut Microbial β-Glucuronidase in Estrogen Reactivation and Breast Cancer
inferred← citeshttps://doi.org/10.3389/fcimb.2021.710945openalex-snapshot
Microbiota-Host-Irinotecan Axis: A New Insight Toward Irinotecan Chemotherapy
inferred← citeshttps://doi.org/10.34172/ajdr.1879openalex-snapshot
Therapeutic Targeting of Akt1 in Oral Squamous Cell Carcinoma Using Natural Cinnamic Acids
inferred← citeshttps://doi.org/10.47836/mjmhs.v22i1.1476openalex-snapshot
Antibacterial Susceptibilities of Moringa Oleifera Leaf Extract (MOLE) Against Gram-positive and Gram-negative Bacteria: A Preliminary Study
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