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Opposite-polarity motors activate one another to trigger cargo transport in live cells

https://doi.org/10.1083/jcb.200908075
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/dvdy.20770openalex-snapshot
Microtubule polarity and axis formation in the Drosophila oocyte
inferredcites →https://doi.org/10.1006/jmbi.1997.1319openalex-snapshot
Kinetic evidence for low chemical processivity in ncd and Eg5
inferredcites →https://doi.org/10.1007/s00249-007-0134-6openalex-snapshot
Load-dependent release limits the processive stepping of the tetrameric Eg5 motor
inferredcites →https://doi.org/10.1016/j.bpj.2009.01.015openalex-snapshot
Obstacles on the Microtubule Reduce the Processivity of Kinesin-1 in a Minimal In Vitro System and in Cell Extract
inferredcites →https://doi.org/10.1016/j.ceb.2006.12.011openalex-snapshot
To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5
inferredcites →https://doi.org/10.1016/j.cell.2008.10.021openalex-snapshot
Consequences of Motor Copy Number on the Intracellular Transport of Kinesin-1-Driven Lipid Droplets
inferredcites →https://doi.org/10.1016/j.cell.2008.11.046openalex-snapshot
The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility
inferredcites →https://doi.org/10.1016/j.conb.2004.08.011openalex-snapshot
Molecular motors in neuronal development, intracellular transport and diseases
inferredcites →https://doi.org/10.1016/j.cub.2003.08.032openalex-snapshot
A Determinant for Directionality of Organelle Transport in Drosophila Embryos
inferredcites →https://doi.org/10.1016/j.cub.2003.10.046openalex-snapshot
Halo: A Guiding Light for Transport
inferredcites →https://doi.org/10.1016/j.cub.2004.05.030openalex-snapshot
Monastrol stabilises an attached low-friction mode of Eg5
inferredcites →https://doi.org/10.1016/j.cub.2004.06.045openalex-snapshot
Bidirectional Transport along Microtubules
inferredcites →https://doi.org/10.1016/j.cub.2005.08.027openalex-snapshot
Microtubule Motors: LSD2 Trips the Toggle
inferredcites →https://doi.org/10.1016/j.cub.2007.06.062openalex-snapshot
Control of a Kinesin-Cargo Linkage Mechanism by JNK Pathway Kinases
inferredcites →https://doi.org/10.1016/j.cub.2007.12.056openalex-snapshot
Minus-End-Directed Motor Ncd Exhibits Processive Movement that Is Enhanced by Microtubule Bundling In Vitro
inferredcites →https://doi.org/10.1016/j.cub.2008.12.043openalex-snapshot
ARF6 Interacts with JIP4 to Control a Motor Switch Mechanism Regulating Endosome Traffic in Cytokinesis
inferredcites →https://doi.org/10.1016/j.devcel.2008.06.014openalex-snapshot
Multiple Kinesin Motors Coordinate Cytoplasmic RNA Transport on a Subpopulation of Microtubules in Xenopus Oocytes
inferredcites →https://doi.org/10.1016/j.jmb.2006.04.062openalex-snapshot
Molecular Dissection of the Inhibitor Binding Pocket of Mitotic Kinesin Eg5 Reveals Mutants that Confer Resistance to Antimitotic Agents
inferredcites →https://doi.org/10.1016/j.tcb.2004.12.007openalex-snapshot
Kinesin: walking, crawling or sliding along?
inferredcites →https://doi.org/10.1016/j.tcb.2009.01.005openalex-snapshot
Huntingtin as an essential integrator of intracellular vesicular trafficking
inferredcites →https://doi.org/10.1016/s0092-8674(02)00708-0openalex-snapshot
Role of Phosphatidylinositol(4,5)bisphosphate Organization in Membrane Transport by the Unc104 Kinesin Motor
inferredcites →https://doi.org/10.1016/s0960-9822(00)00316-xopenalex-snapshot
Role of the kinesin neck linker and catalytic core in microtubule-based motility
inferredcites →https://doi.org/10.1016/s0960-9822(02)01303-9openalex-snapshot
The Cytoplasmic Dynein and Kinesin Motors Have Interdependent Roles in Patterning the Drosophila Oocyte
inferredcites →https://doi.org/10.1021/bi991500bopenalex-snapshot
Kinetic Studies of Dimeric Ncd: Evidence That Ncd Is Not Processive
inferredcites →https://doi.org/10.1038/27463openalex-snapshot
Direction determination in the minus-end-directed kinesin motor ncd
inferredcites →https://doi.org/10.1038/312237a0openalex-snapshot
Dynamic instability of microtubule growth
inferredcites →https://doi.org/10.1038/35024000openalex-snapshot
Microtubule motors in mitosis
inferredcites →https://doi.org/10.1038/379270a0openalex-snapshot
A bipolar kinesin
inferredcites →https://doi.org/10.1038/emboj.2008.133openalex-snapshot
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
inferredcites →https://doi.org/10.1038/nature03503openalex-snapshot
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
inferredcites →https://doi.org/10.1038/ncb1394openalex-snapshot
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
inferredcites →https://doi.org/10.1038/nchembio812openalex-snapshot
Allosteric inhibition of kinesin-5 modulates its processive directional motility
inferredcites →https://doi.org/10.1038/nn1936openalex-snapshot
A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport
inferredcites →https://doi.org/10.1038/sj.emboj.7601108openalex-snapshot
A structural model for monastrol inhibition of dimeric kinesin Eg5
inferredcites →https://doi.org/10.1073/pnas.0408114101openalex-snapshot
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein
inferredcites →https://doi.org/10.1073/pnas.0436709100openalex-snapshot
Probing the kinesin reaction cycle with a 2D optical force clamp
inferredcites →https://doi.org/10.1073/pnas.0606794103openalex-snapshot
Two modes of microtubule sliding driven by cytoplasmic dynein
inferredcites →https://doi.org/10.1073/pnas.0610628104openalex-snapshot
Huntingtin facilitates dynein/dynactin-mediated vesicle transport
inferredcites →https://doi.org/10.1073/pnas.0706825105openalex-snapshot
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
inferredcites →https://doi.org/10.1073/pnas.0906524106openalex-snapshot
Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes
inferredcites →https://doi.org/10.1073/pnas.110149597openalex-snapshot
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
inferredcites →https://doi.org/10.1073/pnas.94.22.12180openalex-snapshot
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
inferredcites →https://doi.org/10.1074/jbc.m511735200openalex-snapshot
S-Trityl-L-cysteine Is a Reversible, Tight Binding Inhibitor of the Human Kinesin Eg5 That Specifically Blocks Mitotic Progression
inferredcites →https://doi.org/10.1083/jcb.143.6.1547openalex-snapshot
Heterotrimeric Kinesin II Is the Microtubule Motor Protein Responsible for Pigment Dispersion in Xenopus Melanophores
inferredcites →https://doi.org/10.1083/jcb.152.5.959openalex-snapshot
Cargo of Kinesin Identified as Jip Scaffolding Proteins and Associated Signaling Molecules
inferredcites →https://doi.org/10.1083/jcb.200105055openalex-snapshot
Interactions and regulation of molecular motors in Xenopus melanophores
inferredcites →https://doi.org/10.1083/jcb.200109047openalex-snapshot
Coordination of opposite-polarity microtubule motors
inferredcites →https://doi.org/10.1083/jcb.200303022openalex-snapshot
The roles of microtubule-based motor proteins in mitosis
inferredcites →https://doi.org/10.1083/jcb.200608128openalex-snapshot
Microtubule binding by dynactin is required for microtubule organization but not cargo transport
inferredcites →https://doi.org/10.1083/jcb.45.2.334openalex-snapshot
THE ASSOCIATION OF A CLASS OF SALTATORY MOVEMENTS WITH MICROTUBULES IN CULTURED CELLS
inferredcites →https://doi.org/10.1091/mbc.10.11.3717openalex-snapshot
Cytoplasmic Dynein, the Dynactin Complex, and Kinesin Are Interdependent and Essential for Fast Axonal Transport
inferredcites →https://doi.org/10.1091/mbc.e05-06-0526openalex-snapshot
Kinesin-1 and Dynein Are the Primary Motors for Fast Transport of Mitochondria in Drosophila Motor Axons
inferredcites →https://doi.org/10.1091/mbc.e07-03-0261openalex-snapshot
Identification of an Axonal Kinesin-3 Motor for Fast Anterograde Vesicle Transport that Facilitates Retrograde Transport of Neuropeptides
inferredcites →https://doi.org/10.1091/mbc.e09-04-0304openalex-snapshot
Tight Functional Coupling of Kinesin-1A and Dynein Motors in the Bidirectional Transport of Neurofilaments
inferredcites →https://doi.org/10.1093/emboj/19.20.5308openalex-snapshot
Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head–Nkin neck chimera with conventional kinesin
inferredcites →https://doi.org/10.1093/emboj/cdg592openalex-snapshot
Bicaudal D induces selective dynein‐mediated microtubule minus end‐directed transport
inferredcites →https://doi.org/10.1126/science.1073386openalex-snapshot
Conversion of Unc104/KIF1A Kinesin into a Processive Motor After Dimerization
inferredcites →https://doi.org/10.1126/science.1093753openalex-snapshot
Kinesin Walks Hand-Over-Hand
inferredcites →https://doi.org/10.1126/science.1108408openalex-snapshot
Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?
inferredcites →https://doi.org/10.1126/science.1157983openalex-snapshot
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
inferredcites →https://doi.org/10.1128/jvi.01718-08openalex-snapshot
Herpesvirus Interactions with the Host Cytoskeleton
inferredcites →https://doi.org/10.1128/mcb.25.7.2733-2743.2005openalex-snapshot
Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways
inferredcites →https://doi.org/10.1146/annurev.biophys.050708.133732openalex-snapshot
Mechanical Signaling in Networks of Motor and Cytoskeletal Proteins
inferredcites →https://doi.org/10.1152/physrev.00023.2007openalex-snapshot
Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics
inferredcites →https://doi.org/10.1242/dev.02514openalex-snapshot
Milton controls the early acquisition of mitochondria byDrosophilaoocytes
inferredcites →https://doi.org/10.1242/jcs.02745openalex-snapshot
The axonal transport of mitochondria
inferredcites →https://doi.org/10.1242/jcs.02979openalex-snapshot
Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites
inferredcites →https://doi.org/10.1242/jcs.038497openalex-snapshot
Ncd motor binding and transport in the spindle
inferredcites →https://doi.org/10.1242/jcs.053850openalex-snapshot
The axonal transport of mitochondria

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A Sphingolipid-mTORC1 Nutrient-Sensing Machinery Enables Animal Development by Suppression of the Intestinal Peroxisome Relocation, Hormone Secretion and the Gut-Brain Crosstalk
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Numerical investigation of axonal cargo rerouting in a dendrite: A three kinetic state model
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inferred← citeshttps://doi.org/10.1002/jnr.23388openalex-snapshot
Live cell imaging reveals differential modifications to cytoplasmic dynein properties by phospho‐ and dephosphomimic mutations of the intermediate chain 2C S84
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Insights on UNC‐104‐dynein/dynactin interactions and their implications on axonal transport in Caenorhabditis elegans
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Reconstitution of Organelle Transport Along Microtubules In Vitro
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Manipulation and Visualization of Peroxisomes in Drosophila
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Organization of Intracellular Transport
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Live Imaging of Peroxisomes and Peroxules in Plants
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Regulation of peroxisomal trafficking and distribution
inferred← citeshttps://doi.org/10.1007/s10571-015-0165-yopenalex-snapshot
Habituation-Like Decrease of Acetylcholine-Induced Inward Current in Helix Command Neurons: Role of Microtubule Motor Proteins
inferred← citeshttps://doi.org/10.1007/s10955-010-0037-2openalex-snapshot
A Hopping Mechanism for Cargo Transport by Molecular Motors on Crowded Microtubules
inferred← citeshttps://doi.org/10.1007/s10955-017-1894-8openalex-snapshot
Role of Interactions and Correlations on Collective Dynamics of Molecular Motors Along Parallel Filaments
inferred← citeshttps://doi.org/10.1007/s11538-012-9745-xopenalex-snapshot
From the Cell Membrane to the Nucleus: Unearthing Transport Mechanisms for Dynein
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Analysis of Cooperative Behavior in Multiple Kinesins Motor Protein Transport by Varying Structural and Chemical Properties
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.30033-5openalex-snapshot
Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair
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Modeling Intracellular Transport in Neurons
inferred← citeshttps://doi.org/10.1016/b978-0-12-809470-9.00007-2openalex-snapshot
Mechanics of bidirectional cargo transport
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00161-9openalex-snapshot
Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2023.12.005openalex-snapshot
Coordination, cooperation, competition, crowding and congestion of molecular motors: Theoretical models and computer simulations
inferred← citeshttps://doi.org/10.1016/bs.mcb.2015.06.014openalex-snapshot
Imaging of motor-dependent transport in neuronal and nonneuronal cells at high spatial and temporal resolution
inferred← citeshttps://doi.org/10.1016/j.bbagen.2017.09.009openalex-snapshot
Mechanical coupling of microtubule-dependent motor teams during peroxisome transport in Drosophila S2 cells
inferred← citeshttps://doi.org/10.1016/j.bbalip.2015.04.002openalex-snapshot
As the fat flies: The dynamic lipid droplets of Drosophila embryos
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2013.08.002openalex-snapshot
Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2019.118572openalex-snapshot
Fluorescence correlation spectroscopy reveals the dynamics of kinesins interacting with organelles during microtubule-dependent transport in cells
inferred← citeshttps://doi.org/10.1016/j.bpj.2010.07.055openalex-snapshot
Probing Intracellular Motor Protein Activity Using an Inducible Cargo Trafficking Assay
inferred← citeshttps://doi.org/10.1016/j.bpj.2011.05.067openalex-snapshot
Productive Cooperation among Processive Motors Depends Inversely on Their Mechanochemical Efficiency
inferred← citeshttps://doi.org/10.1016/j.bpj.2013.03.050openalex-snapshot
Kinesin-5 Seems to Step to its Own Unique Tune, but Really it’s a Cover
inferred← citeshttps://doi.org/10.1016/j.bpj.2019.01.036openalex-snapshot
Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors
inferred← citeshttps://doi.org/10.1016/j.ceb.2009.12.014openalex-snapshot
Coordination of molecular motors: from in vitro assays to intracellular dynamics
inferred← citeshttps://doi.org/10.1016/j.ceb.2010.04.008openalex-snapshot
Linking molecular motors to membrane cargo
inferred← citeshttps://doi.org/10.1016/j.ceb.2013.02.018openalex-snapshot
The journey of the organelle: teamwork and regulation in intracellular transport
inferred← citeshttps://doi.org/10.1016/j.cell.2011.01.021openalex-snapshot
Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.12.051openalex-snapshot
A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.08.076openalex-snapshot
Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.08.027openalex-snapshot
Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity
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A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114649openalex-snapshot
Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport
inferred← citeshttps://doi.org/10.1016/j.cub.2010.03.018openalex-snapshot
Bidirectional Transport: Matchmaking for Motors
inferred← citeshttps://doi.org/10.1016/j.cub.2013.03.068openalex-snapshot
Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin
inferred← citeshttps://doi.org/10.1016/j.cub.2013.04.050openalex-snapshot
Initial Neurite Outgrowth in Drosophila Neurons Is Driven by Kinesin-Powered Microtubule Sliding
inferred← citeshttps://doi.org/10.1016/j.cub.2016.01.048openalex-snapshot
Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity
inferred← citeshttps://doi.org/10.1016/j.cub.2018.03.041openalex-snapshot
Coin Tossing Explains the Activity of Opposing Microtubule Motors on Phagosomes
inferred← citeshttps://doi.org/10.1016/j.cub.2026.07.018openalex-snapshot
Bicaudal D acts as a sensor to enable dynein-kinesin co-dependence
inferred← citeshttps://doi.org/10.1016/j.devcel.2012.11.005openalex-snapshot
Directional Persistence of Migrating Cells Requires Kif1C-Mediated Stabilization of Trailing Adhesions
inferred← citeshttps://doi.org/10.1016/j.devcel.2015.08.020openalex-snapshot
Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells
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The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance
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Multiple roles for the cytoskeleton in ALS
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Coupling a dynein transport model with a model of anterograde and retrograde transport of intracellular organelles
inferred← citeshttps://doi.org/10.1016/j.icheatmasstransfer.2011.08.016openalex-snapshot
An analytical solution describing retrograde viral transport in an axon
inferred← citeshttps://doi.org/10.1016/j.icheatmasstransfer.2011.08.018openalex-snapshot
Effect of pharmaceutical agent degradation on axonal transport drug delivery: An analytical solution for a transient situation
inferred← citeshttps://doi.org/10.1016/j.icheatmasstransfer.2012.01.013openalex-snapshot
Modeling transport of tau in an axon after a photobleaching experiment
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102150openalex-snapshot
The sodium proton exchanger NHE9 regulates phagosome maturation and bactericidal activity in macrophages
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Modeling bidirectional transport of quantum dot nanoparticles in membrane nanotubes
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Which way to go? Cytoskeletal organization and polarized transport in neurons
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Tau/PTL-1 associates with kinesin-3 KIF1A/UNC-104 and affects the motor's motility characteristics in C. elegans neurons
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KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons
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Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease
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TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites
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The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.04.011openalex-snapshot
The role of the cytoskeleton and molecular motors in endosomal dynamics
inferred← citeshttps://doi.org/10.1016/j.tcb.2013.06.003openalex-snapshot
Teamwork in microtubule motors
inferred← citeshttps://doi.org/10.1016/j.tcb.2016.09.005openalex-snapshot
Hitchhiking: A Non-Canonical Mode of Microtubule-Based Transport
inferred← citeshttps://doi.org/10.1016/j.tcb.2017.02.005openalex-snapshot
Moonlighting Motors: Kinesin, Dynein, and Cell Polarity
inferred← citeshttps://doi.org/10.1016/j.tibs.2020.02.002openalex-snapshot
Activation and Regulation of Cytoplasmic Dynein
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.09.014openalex-snapshot
Lysosome-associated membrane proteins (LAMPs) regulate intracellular positioning of mitochondria in MC3T3-E1 cells
inferred← citeshttps://doi.org/10.1021/acs.biochem.9b00907openalex-snapshot
Adapter Proteins for Opposing Motors Interact Simultaneously with Nuclear Pore Protein Nup358
inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00638openalex-snapshot
Manipulation and Motion of Organelles and Single Molecules in Living Cells
inferred← citeshttps://doi.org/10.1021/acs.jpcb.2c05194openalex-snapshot
Tug-of-War and Coordination in Bidirectional Transport by Molecular Motors
inferred← citeshttps://doi.org/10.1021/acs.jpclett.2c01659openalex-snapshot
Cooperation and Competition Coexist in Bidirectional Transport by Motor Proteins
inferred← citeshttps://doi.org/10.1021/cr4005555openalex-snapshot
Single-Molecule Fluorescence and in Vivo Optical Traps: How Multiple Dyneins and Kinesins Interact
inferred← citeshttps://doi.org/10.1021/jp304018bopenalex-snapshot
How the Interplay between Mechanical and Nonmechanical Interactions Affects Multiple Kinesin Dynamics
inferred← citeshttps://doi.org/10.1038/emboj.2011.283openalex-snapshot
Coupling viruses to dynein and kinesin‐1
inferred← citeshttps://doi.org/10.1038/ncomms12259openalex-snapshot
Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro
inferred← citeshttps://doi.org/10.1038/ncomms2037openalex-snapshot
Rotational dynamics of cargos at pauses during axonal transport
inferred← citeshttps://doi.org/10.1038/ncomms7660openalex-snapshot
HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus
inferred← citeshttps://doi.org/10.1038/nrm2845openalex-snapshot
In brief
inferred← citeshttps://doi.org/10.1038/nrm3853openalex-snapshot
Bidirectional cargo transport: moving beyond tug of war
inferred← citeshttps://doi.org/10.1038/nrn.2016.100openalex-snapshot
The cellular mechanisms that maintain neuronal polarity
inferred← citeshttps://doi.org/10.1038/s41582-019-0257-2openalex-snapshot
Axonal transport and neurological disease
inferred← citeshttps://doi.org/10.1038/s41594-024-01418-zopenalex-snapshot
KIF1C activates and extends dynein movement through the FHF cargo adapter
inferred← citeshttps://doi.org/10.1038/s41594-025-01524-6openalex-snapshot
Microtubule motors of opposite polarity cooperate rather than compete in cargo transport
inferred← citeshttps://doi.org/10.1038/s41598-018-29818-4openalex-snapshot
The actin capping protein in Aspergillus nidulans enhances dynein function without significantly affecting Arp1 filament assembly
inferred← citeshttps://doi.org/10.1039/c0sm00927jopenalex-snapshot
Crosstalk between non-processive myosin motors mediated by the actin filament elasticity
inferred← citeshttps://doi.org/10.1039/c5sm01609fopenalex-snapshot
Collective dynamics of processive cytoskeletal motors
inferred← citeshttps://doi.org/10.1042/bst0391126openalex-snapshot
Bidirectional intracellular transport: utility and mechanism
inferred← citeshttps://doi.org/10.1042/bst0391169openalex-snapshot
Cytoplasmic dynein
inferred← citeshttps://doi.org/10.1042/cbi20110413openalex-snapshot
Bidirectional transport of organelles: unity and struggle of opposing motors
inferred← citeshttps://doi.org/10.1063/1.4921591openalex-snapshot
Real-time investigation of dynamic protein crystallization in living cells
inferred← citeshttps://doi.org/10.1063/1.4921591.4openalex-snapshot
10.1063/1.4921591.4
inferred← citeshttps://doi.org/10.1063/1.4921591.7openalex-snapshot
10.1063/1.4921591.7
inferred← citeshttps://doi.org/10.1073/pnas.1004736107openalex-snapshot
Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
inferred← citeshttps://doi.org/10.1073/pnas.1015839108openalex-snapshot
Transient binding of dynein controls bidirectional long-range motility of early endosomes
inferred← citeshttps://doi.org/10.1073/pnas.1104298108openalex-snapshot
Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport
inferred← citeshttps://doi.org/10.1073/pnas.1107841108openalex-snapshot
Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport
inferred← citeshttps://doi.org/10.1073/pnas.1201390110openalex-snapshot
Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors
inferred← citeshttps://doi.org/10.1073/pnas.1219961110openalex-snapshot
In vivo optical trapping indicates kinesin’s stall force is reduced by dynein during intracellular transport
inferred← citeshttps://doi.org/10.1073/pnas.1522424113openalex-snapshot
Microtubule–microtubule sliding by kinesin-1 is essential for normal cytoplasmic streaming in Drosophila oocytes
inferred← citeshttps://doi.org/10.1073/pnas.2113795119openalex-snapshot
De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors
inferred← citeshttps://doi.org/10.1074/jbc.m111.296582openalex-snapshot
Cooperative Responses of Multiple Kinesins to Variable and Constant Loads
inferred← citeshttps://doi.org/10.1080/10255842.2011.607445openalex-snapshot
Analytical modelling of retrograde transport of nerve growth factors in an axon: a transient problem
inferred← citeshttps://doi.org/10.1080/10255842.2011.632376openalex-snapshot
An analytical solution describing the propagation of positive injury signals in an axon: effect of dynein velocity distribution
inferred← citeshttps://doi.org/10.1080/10255842.2012.662679openalex-snapshot
An exact solution of transient equations describing slow axonal transport
inferred← citeshttps://doi.org/10.1083/jcb.1877iti1openalex-snapshot
Opposing motors take the strain
inferred← citeshttps://doi.org/10.1083/jcb.201004118openalex-snapshot
Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei
inferred← citeshttps://doi.org/10.1083/jcb.201104076openalex-snapshot
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
inferred← citeshttps://doi.org/10.1083/jcb.201112101openalex-snapshot
Lis1 is an initiation factor for dynein-driven organelle transport
inferred← citeshttps://doi.org/10.1083/jcb.201307116openalex-snapshot
PKA-dependent dynein switching from lysosomes to adenovirus: A novel form of host–virus competition
inferred← citeshttps://doi.org/10.1083/jcb.201708122openalex-snapshot
New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes
inferred← citeshttps://doi.org/10.1083/jcb.201709174openalex-snapshot
Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination
inferred← citeshttps://doi.org/10.1083/jcb.202205136openalex-snapshot
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport
inferred← citeshttps://doi.org/10.1083/jcb.202309084openalex-snapshot
Dynein and dynactin move long-range but are delivered separately to the axon tip
inferred← citeshttps://doi.org/10.1083/jcb.202405032openalex-snapshot
Nesprin-2 coordinates opposing microtubule motors during nuclear migration in neurons
inferred← citeshttps://doi.org/10.1088/0953-8984/25/46/463101openalex-snapshot
Motor proteins and molecular motors: how to operate machines at the nanoscale
inferred← citeshttps://doi.org/10.1088/1478-3975/10/1/016003openalex-snapshot
Characterization of bidirectional molecular motor-assisted transport models
inferred← citeshttps://doi.org/10.1088/1478-3975/aba5e5openalex-snapshot
Getting around the cell: physical transport in the intracellular world
inferred← citeshttps://doi.org/10.1091/mbc.e10-09-0741openalex-snapshot
CK1 activates minus-end–directed transport of membrane organelles along microtubules
inferred← citeshttps://doi.org/10.1091/mbc.e11-03-0217openalex-snapshot
Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array
inferred← citeshttps://doi.org/10.1091/mbc.e11-11-0938openalex-snapshot
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis inDrosophila
inferred← citeshttps://doi.org/10.1091/mbc.e12-12-0858openalex-snapshot
Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons
inferred← citeshttps://doi.org/10.1091/mbc.e14-10-1423openalex-snapshot
Kinesin-1–powered microtubule sliding initiates axonal regeneration in Drosophila cultured neurons
inferred← citeshttps://doi.org/10.1091/mbc.e23-01-0020openalex-snapshot
Tubulin CFEOM mutations both inhibit or activate kinesin motor activity
inferred← citeshttps://doi.org/10.1093/brain/awu097openalex-snapshot
DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy
inferred← citeshttps://doi.org/10.1096/fj.14-250019openalex-snapshot
Microtubule‐dependent transport of vimentin filament precursors is regulated by actin and by the concerted action of Rho‐ and p21‐activated kinases
inferred← citeshttps://doi.org/10.1098/rsob.120183openalex-snapshot
Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2
inferred← citeshttps://doi.org/10.1098/rspa.2012.0061openalex-snapshot
An exact solution describing slow axonal transport of cytoskeletal elements: the effect of a finite half-life
inferred← citeshttps://doi.org/10.1101/2021.05.06.443034openalex-snapshot
Coil-to-Helix Transition at the Nup358-BicD2 Interface Activates BicD2 for Dynein Recruitment
inferred← citeshttps://doi.org/10.1101/2021.05.15.444169openalex-snapshot
A lipid-mTORC1 nutrient sensing pathway regulates animal development by peroxisome-derived hormones
inferred← citeshttps://doi.org/10.1101/2021.06.10.447989openalex-snapshot
Cargo-mediated mechanisms reduce inter-motor mechanical interference, promote load-sharing and enhance processivity in teams of molecular motors
inferred← citeshttps://doi.org/10.1101/2023.03.19.533383openalex-snapshot
Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling
inferred← citeshttps://doi.org/10.1101/250175openalex-snapshot
Dynein catch bond as a mediator of codependent bidirectional cellular transport
inferred← citeshttps://doi.org/10.1103/physreve.101.062416openalex-snapshot
Intracellular motor-driven transport of rodlike smooth organelles along microtubules
inferred← citeshttps://doi.org/10.1103/physrevresearch.1.023019openalex-snapshot
Dynein catch bond as a mediator of codependent bidirectional cellular transport
inferred← citeshttps://doi.org/10.1111/tra.12037openalex-snapshot
Endogenous GSK ‐3/Shaggy Regulates Bidirectional Axonal Transport of the Amyloid Precursor Protein
inferred← citeshttps://doi.org/10.1111/tra.12070openalex-snapshot
Distinct Functions of Nuclear Distribution Proteins LIS1 , Ndel1 and NudCL in Regulating Axonal Mitochondrial Transport
inferred← citeshttps://doi.org/10.1111/tra.12475openalex-snapshot
Regulation of dynein‐dynactin‐driven vesicular transport
inferred← citeshttps://doi.org/10.1111/tra.12537openalex-snapshot
Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams
inferred← citeshttps://doi.org/10.1115/1.4056915openalex-snapshot
Dynein Dysfunction Prevents Maintenance of High Concentrations of Slow Axonal Transport Cargos at the Axon Terminal: A Computational Study
inferred← citeshttps://doi.org/10.1134/s0006297917070057openalex-snapshot
Intracellular cargo transport by kinesin-3 motors
inferred← citeshttps://doi.org/10.1142/s021951941100468xopenalex-snapshot
A THREE-KINETIC-STATE MODEL OF AXONAL TRANSPORT DRUG DELIVERY
inferred← citeshttps://doi.org/10.1146/annurev-biophys-042910-155310openalex-snapshot
Kinesin Assembly and Movement in Cells
inferred← citeshttps://doi.org/10.1146/annurev-biophys-051013-022746openalex-snapshot
Biophysical Challenges to Axonal Transport: Motor-Cargo Deficiencies and Neurodegeneration
inferred← citeshttps://doi.org/10.1146/annurev-micro-092611-150051openalex-snapshot
Herpesvirus Transport to the Nervous System and Back Again
inferred← citeshttps://doi.org/10.1152/ajpgi.00118.2013openalex-snapshot
Rab1a regulates sorting of early endocytic vesicles
inferred← citeshttps://doi.org/10.1152/ajpregu.00002.2010openalex-snapshot
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure
inferred← citeshttps://doi.org/10.1152/physrev.00023.2007openalex-snapshot
Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics
inferred← citeshttps://doi.org/10.1242/bio.2012307openalex-snapshot
Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon
inferred← citeshttps://doi.org/10.1242/bio.20147633openalex-snapshot
Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport
inferred← citeshttps://doi.org/10.1242/dmm.052405openalex-snapshot
14-3-3θ phosphorylation at S232 reduces its interactome and regulates axonal trafficking
inferred← citeshttps://doi.org/10.1242/jcs.053850openalex-snapshot
The axonal transport of mitochondria
inferred← citeshttps://doi.org/10.1242/jcs.062208openalex-snapshot
Towards a quantitative understanding of mitotic spindle assembly and mechanics
inferred← citeshttps://doi.org/10.1242/jcs.075259openalex-snapshot
The microtubule plus-end localization ofAspergillusdynein is important for dynein–early-endosome interaction but not for dynein ATPase activation
inferred← citeshttps://doi.org/10.1242/jcs.097675openalex-snapshot
Functional coupling of microtubules to membranes – implications for membrane structure and dynamics
inferred← citeshttps://doi.org/10.1242/jcs.115030openalex-snapshot
Microtubule-based transport – basic mechanisms, traffic rules and role in neurological pathogenesis
inferred← citeshttps://doi.org/10.1242/jcs.122317openalex-snapshot
Microtubule motors mediate endosomal sorting by maintaining functional domain organization.
inferred← citeshttps://doi.org/10.1242/jcs.123885openalex-snapshot
Protein kinase Darkener of apricot and its substrate EF1γ regulate organelle transport along microtubules
inferred← citeshttps://doi.org/10.1242/jcs.237016openalex-snapshot
The role of microtubules in secretory protein transport
inferred← citeshttps://doi.org/10.1242/jcs.249938openalex-snapshot
Stable tug-of-war between kinesin-1 and cytoplasmic dynein upon different ATP and roadblock concentrations
inferred← citeshttps://doi.org/10.1242/jcs.262148openalex-snapshot
The role of kinesin-1 in neuronal dense core vesicle transport, locomotion and lifespan regulation in C. elegans
inferred← citeshttps://doi.org/10.1242/jcs.264245openalex-snapshot
Auxin-inducible degradation of UNC-116 in C. elegans inhibits bidirectional dense core vesicle transport and worm locomotion on different timescales
inferred← citeshttps://doi.org/10.1371/journal.pbio.1001551openalex-snapshot
Directional Transport Is Mediated by a Dynein-Dependent Step in an RNA Localization Pathway
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002273openalex-snapshot
Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1010217openalex-snapshot
Cargo surface fluidity can reduce inter-motor mechanical interference, promote load-sharing and enhance processivity in teams of molecular motors
inferred← citeshttps://doi.org/10.1371/journal.pgen.1003066openalex-snapshot
Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model
inferred← citeshttps://doi.org/10.1371/journal.pone.0024479openalex-snapshot
Roles of Dynein and Dynactin in Early Endosome Dynamics Revealed Using Automated Tracking and Global Analysis
inferred← citeshttps://doi.org/10.1371/journal.ppat.1007055openalex-snapshot
Role of kinesins in directed adenovirus transport and cytoplasmic exploration
inferred← citeshttps://doi.org/10.1523/jneurosci.1074-10.2010openalex-snapshot
Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
inferred← citeshttps://doi.org/10.1523/jneurosci.1233-11.2012openalex-snapshot
Mitochondrial Dynamics and Bioenergetic Dysfunction Is Associated with Synaptic Alterations in Mutant SOD1 Motor Neurons
inferred← citeshttps://doi.org/10.17116/molgen2019370113openalex-snapshot
mRNP transport. mRNP transport in the cytoplasm
inferred← citeshttps://doi.org/10.2147/dnnd.s57502openalex-snapshot
Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulation
inferred← citeshttps://doi.org/10.2478/s11534-011-0051-2openalex-snapshot
Analytical investigation of various regimes of retrograde trafficking of neurotropic viruses in axons
inferred← citeshttps://doi.org/10.2478/s11534-011-0070-zopenalex-snapshot
Merging of viral concentration waves in retrograde viral transport in axons
inferred← citeshttps://doi.org/10.2478/s11534-011-0116-2openalex-snapshot
A model of axonal transport drug delivery
inferred← citeshttps://doi.org/10.2478/s11534-012-0051-xopenalex-snapshot
Effect of kinesin velocity distribution on slow axonal transport
inferred← citeshttps://doi.org/10.3103/s089141681901004xopenalex-snapshot
mRNP Transport in Eukaryots: Transport of mRNP Particles in Cytoplasm
inferred← citeshttps://doi.org/10.3109/10409238.2011.572861openalex-snapshot
Molecular motors: directing traffic during RNA localization
inferred← citeshttps://doi.org/10.31274/td-20240329-164openalex-snapshot
Consequences of pathogenic tubulin-mutations on molecular motor proteins and their implications in tubulinopathies
inferred← citeshttps://doi.org/10.3389/fcell.2020.00022openalex-snapshot
The Generation of Dynein Networks by Multi-Layered Regulation and Their Implication in Cell Division
inferred← citeshttps://doi.org/10.3389/fcell.2020.00835openalex-snapshot
Rosy Beginnings: Studying Peroxisomes in Drosophila
inferred← citeshttps://doi.org/10.3389/fncel.2019.00470openalex-snapshot
Crowd Control: Effects of Physical Crowding on Cargo Movement in Healthy and Diseased Neurons
inferred← citeshttps://doi.org/10.3389/fncel.2023.1215945openalex-snapshot
Axonal transport during injury on a theoretical axon
inferred← citeshttps://doi.org/10.3389/fnmol.2017.00424openalex-snapshot
VEGF Axonal Transport Dependent on Kinesin-1B and Microtubules Dynamics
inferred← citeshttps://doi.org/10.3389/fnsyn.2016.00003openalex-snapshot
The Roles of Microtubule-Based Transport at Presynaptic Nerve Terminals
inferred← citeshttps://doi.org/10.3390/cells10020262openalex-snapshot
Mechanisms and Therapeutic Implications of GSK-3 in Treating Neurodegeneration
inferred← citeshttps://doi.org/10.3390/md14050102openalex-snapshot
Axonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of Therapeutics
inferred← citeshttps://doi.org/10.3390/v3030233openalex-snapshot
The Dynactin Complex Enhances the Speed of Microtubule-Dependent Motions of Adenovirus Both Towards and Away from the Nucleus
inferred← citeshttps://doi.org/10.3410/f.717497850.792902901openalex-snapshot
Faculty Opinions recommendation of Lis1 is an initiation factor for dynein-driven organelle transport.
inferred← citeshttps://doi.org/10.3791/50838openalex-snapshot
Organelle Transport in Cultured Drosophila Cells: S2 Cell Line and Primary Neurons.
inferred← citeshttps://doi.org/10.4161/bioa.1.1.14629openalex-snapshot
Watching nuclei move
inferred← citeshttps://doi.org/10.4161/cib.13780openalex-snapshot
Bi-directional transport of the nucleus by dynein and kinesin-1
inferred← citeshttps://doi.org/10.48550/arxiv.1006.5161openalex-snapshot
A hopping mechanism for cargo transport by molecular motors in crowded microtubules
inferred← citeshttps://doi.org/10.48550/arxiv.1107.1507openalex-snapshot
Jamming of molecular motors as a tool for transport cargos along microtubules
inferred← citeshttps://doi.org/10.64898/2026.01.17.700114openalex-snapshot
Structural characterization of a minimal KLC2/Nup358/BicD2 complex
inferred← citeshttps://doi.org/10.70675/1d94d1cdze6b7z41ccz80baz3c7fa8e55e69openalex-snapshot
Etude de l'implication des microtubules dans le trafic intracellulaire
inferred← citeshttps://doi.org/10.70675/25af38bbz9dd0z48fbzb24cza35d0a181013openalex-snapshot
Understanding internal cell coordination during migration
inferred← citeshttps://doi.org/10.70675/5a5d3bacz6b6ez4a35z9159z6459b40efcdfopenalex-snapshot
Huntingtin functions in the regulation of axonal transport : consequences on neuronal network homeostasis and behavior, in health and disease
inferred← citeshttps://doi.org/10.70675/c735a183z2524z4e97z8d81ze3f04b47a7eeopenalex-snapshot
Application of statistical physics tools to intracellular transport
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