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Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

https://doi.org/10.1084/jem.20051921

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Cotransplantation of HLA-Identical Sibling Culture-Expanded Mesenchymal Stem Cells and Hematopoietic Stem Cells in Hematologic Malignancy Patients

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HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells

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Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents

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Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

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Kaposiʼs sarcoma-associated herpesvirus infection prior to onset of Kaposiʼs sarcoma

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The β-core fragment of human chorionic gonadotrophin inhibits growth of Kaposiʼs sarcoma-derived cells and a new immortalized Kaposiʼs sarcoma cell line

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TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

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Gastric Cancer Originating from Bone Marrow-Derived Cells

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Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

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Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues

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Multilineage Potential of Adult Human Mesenchymal Stem Cells

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Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

inferredcites →https://doi.org/10.1128/jvi.75.18.8660-8673.2001openalex-snapshot

Activation of NF-κB by the Human Herpesvirus 8 Chemokine Receptor ORF74: Evidence for a Paracrine Model of Kaposi's Sarcoma Pathogenesis

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Characterization of Biophysical and Metabolic Properties of Cells Labeled with Superparamagnetic Iron Oxide Nanoparticles and Transfection Agent for Cellular MR Imaging

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Inhibitor-κB kinase-β regulates LPS-induced TNF-α production in cardiac myocytes through modulation of NF-κB p65 subunit phosphorylation

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Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis

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Systemic Delivery of Bone Marrow–Derived Mesenchymal Stem Cells to the Infarcted Myocardium

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Local Delivery of Marrow-Derived Stromal Cells Augments Collateral Perfusion Through Paracrine Mechanisms

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Therapeutic Benefit of Intravenous Administration of Bone Marrow Stromal Cells After Cerebral Ischemia in Rats

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Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

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Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI

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Human mesenchymal stem cells modulate allogeneic immune cell responses

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Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells

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Tumor suppressor gene E-cadherin and its role in normal and malignant cells

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Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium

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inferred← citeshttps://doi.org/10.1007/s00441-023-03831-0openalex-snapshot

Exploration of eMSCs with HA-GEL system in repairing damaged endometrium after endometrial cancer with fertility-sparing treatment

inferred← citeshttps://doi.org/10.1007/s00535-015-1040-9openalex-snapshot

Stem cell therapy for inflammatory bowel disease

inferred← citeshttps://doi.org/10.1007/s00535-015-1049-0openalex-snapshot

Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model

inferred← citeshttps://doi.org/10.1007/s00595-011-0107-3openalex-snapshot

Are autologous bone marrow stem cell transplantation and transcatheter arterial embolization the best choices for patients with hepatocellular carcinoma and hepatic dysfunction? Report of a case

inferred← citeshttps://doi.org/10.1007/s10517-016-3561-5openalex-snapshot

Analysis of Proliferation of Melanoma Cells and Mesenchymal Stem Cells in Co-Culture and Contribution of Experimental Conditions into Interpretation of the Results

inferred← citeshttps://doi.org/10.1007/s10549-011-1774-xopenalex-snapshot

The in vitro and in vivo effects of human umbilical cord mesenchymal stem cells on the growth of breast cancer cells

inferred← citeshttps://doi.org/10.1007/s10555-010-9222-7openalex-snapshot

Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

inferred← citeshttps://doi.org/10.1007/s10555-026-10360-zopenalex-snapshot

Sarcoma metastasis: distinct biological principles beyond the carcinoma paradigm

inferred← citeshttps://doi.org/10.1007/s10616-011-9413-2openalex-snapshot

Extended and stable gene expression via nucleofection of MIDGE construct into adult human marrow mesenchymal stromal cells

inferred← citeshttps://doi.org/10.1007/s10911-010-9196-7openalex-snapshot

Mesenchymal Stem Cells in the Pathogenesis and Therapy of Breast Cancer

inferred← citeshttps://doi.org/10.1007/s11010-013-1600-3openalex-snapshot

Differential effects of mesenchymal stem cells on a heterogeneous cell population within lung cancer cell lines

inferred← citeshttps://doi.org/10.1007/s11010-013-1746-zopenalex-snapshot

Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model

inferred← citeshttps://doi.org/10.1007/s11010-013-1836-yopenalex-snapshot

Human umbilical cord mesenchymal stem cells inhibit C6 glioma growth via secretion of dickkopf-1 (DKK1)

inferred← citeshttps://doi.org/10.1007/s11010-016-2909-5openalex-snapshot

Alternative new mesenchymal stem cell source exerts tumor tropism through ALCAM and N-cadherin via regulation of microRNA-192 and -218

inferred← citeshttps://doi.org/10.1007/s11033-011-0760-zopenalex-snapshot

Human amniotic membrane derived-mesenchymal stem cells induce C6 glioma apoptosis in vivo through the Bcl-2/caspase pathways

inferred← citeshttps://doi.org/10.1007/s11515-014-1306-2openalex-snapshot

Mesenchymal stem cells in progression and treatment of cancers

inferred← citeshttps://doi.org/10.1007/s12010-022-04119-9openalex-snapshot

In Vitro and In Vivo Comparative Analysis of Differentially Expressed Genes and Signaling Pathways in Breast Cancer Cells on Interaction with Mesenchymal Stem Cells

inferred← citeshttps://doi.org/10.1007/s12013-014-0420-8openalex-snapshot

Hypoxia-Inducible Factor 1-Alpha Regulates Cancer-Inhibitory Effect of Human Mesenchymal Stem Cells

inferred← citeshttps://doi.org/10.1007/s12015-007-0001-yopenalex-snapshot

The Wnt Signal Transduction Pathway in Stem Cells and Cancer Cells: Influence on Cellular Invasion

inferred← citeshttps://doi.org/10.1007/s12015-008-9030-4openalex-snapshot

Mesenchymal Stem Cells in Cancer

inferred← citeshttps://doi.org/10.1007/s12015-011-9345-4openalex-snapshot

Multipotent Mesenchymal Stromal Cell Therapy and Risk of Malignancies

inferred← citeshttps://doi.org/10.1007/s12015-014-9514-3openalex-snapshot

Human Wharton's Jelly Stem Cells, its Conditioned Medium and Cell-Free Lysate Inhibit the Growth of Human Lymphoma Cells

inferred← citeshttps://doi.org/10.1007/s12015-018-9806-0openalex-snapshot

Human Adipose Tissue Stem Cells Promote the Growth of Acute Lymphoblastic Leukemia Cells in NOD/SCID Mice

inferred← citeshttps://doi.org/10.1007/s12015-018-9824-yopenalex-snapshot

Mesenchymal Stem Cells: Miraculous Healers or Dormant Killers?

inferred← citeshttps://doi.org/10.1007/s12015-023-10568-4openalex-snapshot

Improving Autologous Fat Grafting in Regenerative Surgery through Stem Cell-Assisted Lipotransfer

inferred← citeshttps://doi.org/10.1007/s12029-021-00762-3openalex-snapshot

Evaluation of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells Conditioning Medium (hWJ-MSCs-CM) or Scorpion Venom Breast Cancer Cell Line In Vitro

inferred← citeshttps://doi.org/10.1007/s12094-012-0860-9openalex-snapshot

Murine bone marrow stromal cells pulsed with homologous tumor-derived exosomes inhibit proliferation of liver cancer cells

inferred← citeshttps://doi.org/10.1007/s12094-017-1677-3openalex-snapshot

Inhibitory effect and mechanism of mesenchymal stem cells on melanoma cells

inferred← citeshttps://doi.org/10.1007/s12668-021-00931-5openalex-snapshot

Analysis of the Interaction of Human Neuroblastoma Cell-Derived Cytochalasin B Induced Membrane Vesicles with Mesenchymal Stem Cells Using Imaging Flow Cytometry

inferred← citeshttps://doi.org/10.1007/s13233-016-4107-4openalex-snapshot

Superiority of three-dimensional stem cell clusters over monolayer culture: An archetype to biological application

inferred← citeshttps://doi.org/10.1007/s13277-013-1165-5openalex-snapshot

Inhibitory effect and mechanism of mesenchymal stem cells on liver cancer cells

inferred← citeshttps://doi.org/10.1007/s13402-017-0335-7openalex-snapshot

MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells

inferred← citeshttps://doi.org/10.1007/s13402-018-0378-4openalex-snapshot

The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications

inferred← citeshttps://doi.org/10.1007/s13402-019-00459-7openalex-snapshot

The therapeutic potential of mesenchymal stem cells in lung cancer: benefits, risks and challenges

inferred← citeshttps://doi.org/10.1007/s13577-020-00332-yopenalex-snapshot

Effect of the extracellular component of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis

inferred← citeshttps://doi.org/10.1007/s13770-018-0128-8openalex-snapshot

The Use of Normal Stem Cells and Cancer Stem Cells for Potential Anti-Cancer Therapeutic Strategy

inferred← citeshttps://doi.org/10.1016/b978-0-12-384913-7.00016-2openalex-snapshot

Mesenchymal Stem Cells, Inflammation, and Neurodegenerative Diseases

inferred← citeshttps://doi.org/10.1016/b978-0-12-416606-6.00001-5openalex-snapshot

Genetically Engineered Mesenchymal Stem Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-803102-5.00022-7openalex-snapshot

Therapeutic Purposes and Risks of Ex Vivo Expanded Mesenchymal Stem/Stromal Cells

inferred← citeshttps://doi.org/10.1016/b978-0-12-803892-5.00016-4openalex-snapshot

Adipose Tissue-Derived Stem Cells in Regenerative Medicine and Impact on Cancer

inferred← citeshttps://doi.org/10.1016/b978-0-323-95346-7.00001-4openalex-snapshot

Mesenchymal stem cells: A promising weapon for cancer therapy

inferred← citeshttps://doi.org/10.1016/b978-0-443-15717-2.00128-1openalex-snapshot

Pro- and Anti-Cancer Behaviors of Mesenchymal Stem Cells

inferred← citeshttps://doi.org/10.1016/b978-0-443-45056-3.00016-9openalex-snapshot

Mesenchymal stem cell-derived extracellular vesicles in cancer immunotherapy

inferred← citeshttps://doi.org/10.1016/bs.acr.2015.04.012openalex-snapshot

Stem Cell-Based Therapies for Cancer

inferred← citeshttps://doi.org/10.1016/j.addr.2011.06.010openalex-snapshot

Mesenchymal stem cells engineered for cancer therapy

inferred← citeshttps://doi.org/10.1016/j.ahj.2018.02.009openalex-snapshot

Rationale and Design of the SENECA (StEm cell iNjECtion in cAncer survivors) Trial

inferred← citeshttps://doi.org/10.1016/j.arcmed.2022.11.001openalex-snapshot

Mesenchymal Stem/Stromal Cells in Cancer: from Initiation to Metastasis

inferred← citeshttps://doi.org/10.1016/j.arcmed.2025.103212openalex-snapshot

Effectiveness of Tumor-induced Mesenchymal Stem Cells on Cell Growth and Development in Different Cancer Types In Vitro and In Vivo Models

inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.01.022openalex-snapshot

Bone marrow contributions to fibrosis

inferred← citeshttps://doi.org/10.1016/j.bbcan.2013.10.004openalex-snapshot

Tumor microenvironment: Bone marrow-mesenchymal stem cells as key players

inferred← citeshttps://doi.org/10.1016/j.bbcan.2016.10.004openalex-snapshot

Recent discoveries concerning the tumor - mesenchymal stem cell interactions

inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189277openalex-snapshot

Advancements in immunotherapy for gastric cancer: Unveiling the potential of immune checkpoint inhibitors and emerging strategies

inferred← citeshttps://doi.org/10.1016/j.bbmt.2010.06.004openalex-snapshot

Long-Term Efficacy and Safety of Human Umbilical Cord Mesenchymal Stromal Cells in Rotenone-Induced Hemiparkinsonian Rats

inferred← citeshttps://doi.org/10.1016/j.bihy.2009.01.006openalex-snapshot

A possible mechanism of spontaneous involution of infantile hemangioma

inferred← citeshttps://doi.org/10.1016/j.biocel.2012.04.015openalex-snapshot

IFN-γ-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand

inferred← citeshttps://doi.org/10.1016/j.biocel.2017.12.013openalex-snapshot

The inhibitory influence of adipose tissue-derived mesenchymal stem cell environment and Wnt antagonism on breast tumour cell lines

inferred← citeshttps://doi.org/10.1016/j.biochi.2013.05.010openalex-snapshot

Mesenchymal stem cell secretome and regenerative therapy after cancer

inferred← citeshttps://doi.org/10.1016/j.biochi.2014.06.016openalex-snapshot

Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2011.01.042openalex-snapshot

In vivo magnetic resonance imaging of cell tropsim, trafficking mechanism, and therapeutic impact of human mesenchymal stem cells in a murine glioma model

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.03.014openalex-snapshot

Molecular imaging for assessment of mesenchymal stem cells mediated breast cancer therapy

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2016.02.024openalex-snapshot

Glycoengineered mesenchymal stem cells as an enabling platform for two-step targeting of solid tumors

inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109384openalex-snapshot

The role and prospect of JMJD3 in stem cells and cancer

inferred← citeshttps://doi.org/10.1016/j.biopha.2022.114035openalex-snapshot

Mesenchymal stem cells loaded with Ad5-Ki67/IL-15 enhance oncolytic adenovirotherapy in experimental glioblastoma

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114373openalex-snapshot

The effects of mesenchymal stem cells on the chemotherapy of colorectal cancer

inferred← citeshttps://doi.org/10.1016/j.canlet.2008.04.023openalex-snapshot

Prodrug cancer gene therapy

inferred← citeshttps://doi.org/10.1016/j.canlet.2008.04.032openalex-snapshot

Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling

inferred← citeshttps://doi.org/10.1016/j.canlet.2008.09.039openalex-snapshot

Alveolar rhabdomyosarcoma: Is the cell of origin a mesenchymal stem cell?

inferred← citeshttps://doi.org/10.1016/j.canlet.2009.02.011openalex-snapshot

Naïve human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo

inferred← citeshttps://doi.org/10.1016/j.canlet.2009.02.022openalex-snapshot

Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis

inferred← citeshttps://doi.org/10.1016/j.canlet.2010.04.007openalex-snapshot

Human umbilical cord blood mesenchymal stem cell-derived extracellular matrix prohibits metastatic cancer cell MDA-MB-231 proliferation

inferred← citeshttps://doi.org/10.1016/j.canlet.2011.02.012openalex-snapshot

Potential implications of mesenchymal stem cells in cancer therapy

inferred← citeshttps://doi.org/10.1016/j.canlet.2012.05.027openalex-snapshot

Sarcomas as a mise en abyme of mesenchymal stem cells: Exploiting interrelationships for cell mediated anticancer therapy

inferred← citeshttps://doi.org/10.1016/j.canlet.2014.06.018openalex-snapshot

Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-β and suppress the growth of MCF-7 human breast cancer cells

inferred← citeshttps://doi.org/10.1016/j.canlet.2017.07.024openalex-snapshot

Mesenchymal stroma: Role in osteosarcoma progression

inferred← citeshttps://doi.org/10.1016/j.cis.2024.103331openalex-snapshot

Biohybrid nano-platforms manifesting effective cancer therapy: Fabrication, characterization, challenges and clinical perspective

inferred← citeshttps://doi.org/10.1016/j.colsurfb.2021.112163openalex-snapshot

Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy

inferred← citeshttps://doi.org/10.1016/j.ctrv.2012.03.005openalex-snapshot

Mesenchymal stem cell signaling in cancer progression

inferred← citeshttps://doi.org/10.1016/j.cytogfr.2024.03.002openalex-snapshot

Interleukins and interferons in mesenchymal stromal stem cell-based gene therapy of cancer

inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.172991openalex-snapshot

Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses

inferred← citeshttps://doi.org/10.1016/j.gene.2017.06.012openalex-snapshot

Mesenchymal stem cells can induce regulatory T cells via modulating miR-126a but not miR-10a

inferred← citeshttps://doi.org/10.1016/j.gie.2010.11.008openalex-snapshot

Use of adipose tissue-derived stromal cells for prevention of esophageal stricture after circumferential EMR in a canine model

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e29858openalex-snapshot

Immunogenic cell death mediated TLR3/4-activated MSCs in U87 GBM cell line

inferred← citeshttps://doi.org/10.1016/j.hlc.2012.04.021openalex-snapshot

WITHDRAWN: Molecular Characteristics of Bone Marrow Mesenchymal Stem Cells: An Appealing Source for Regenerative Medicine

inferred← citeshttps://doi.org/10.1016/j.ijcard.2011.11.017openalex-snapshot

Molecular characteristics of bone marrow mesenchymal stem cells, source of regenerative medicine

inferred← citeshttps://doi.org/10.1016/j.ijpx.2025.100375openalex-snapshot

Enhance therapeutic efficacy of BiTE (HER2/CD3) for HER2- positive tumors through in vivo expression

inferred← citeshttps://doi.org/10.1016/j.imlet.2007.04.001openalex-snapshot

IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells

inferred← citeshttps://doi.org/10.1016/j.imlet.2015.06.016openalex-snapshot

Classification and biology of tumour associated stromal cells

inferred← citeshttps://doi.org/10.1016/j.imlet.2015.06.019openalex-snapshot

Organ-specific migration of mesenchymal stromal cells: Who, when, where and why?

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112171openalex-snapshot

Mesenchymal stem cell-derived exosomes for management of prostate cancer: An updated view

inferred← citeshttps://doi.org/10.1016/j.isci.2025.112343openalex-snapshot

NKG2D-CAR-targeted iPSC-derived MSCs efficiently target solid tumors expressing NKG2D ligand

inferred← citeshttps://doi.org/10.1016/j.it.2007.03.001openalex-snapshot

Mesenchymal stem cells: a new strategy for immunosuppression?

inferred← citeshttps://doi.org/10.1016/j.jbo.2019.100231openalex-snapshot

Mesenchymal stromal cells for bone sarcoma treatment: Roadmap to clinical practice

inferred← citeshttps://doi.org/10.1016/j.jconrel.2018.12.005openalex-snapshot

Radiolabeling of cell membrane-based nano-vesicles with 14C-linoleic acid for robust and sensitive quantification of their biodistribution

inferred← citeshttps://doi.org/10.1016/j.jcyt.2013.06.010openalex-snapshot

Immortalized human fetal bone marrow-derived mesenchymal stromal cell expressing suicide gene for anti-tumor therapy in vitro and in vivo

inferred← citeshttps://doi.org/10.1016/j.jcyt.2013.11.012openalex-snapshot

Human adipose-derived mesenchymal stromal cell pigment epithelium–derived factor cytotherapy modifies genetic and epigenetic profiles of prostate cancer cells

inferred← citeshttps://doi.org/10.1016/j.jcyt.2014.05.006openalex-snapshot

Effect of bone marrow–derived mesenchymal stromal cells on hepatoma

inferred← citeshttps://doi.org/10.1016/j.jcyt.2014.10.015openalex-snapshot

Human mesenchymal stromal cell therapy for prevention and recovery of chemo/radiotherapy adverse reactions

inferred← citeshttps://doi.org/10.1016/j.jcyt.2015.03.603openalex-snapshot

Mesenchymal stromal cell delivery of full-length tumor necrosis factor–related apoptosis-inducing ligand is superior to soluble type for cancer therapy

inferred← citeshttps://doi.org/10.1016/j.jcyt.2016.09.003openalex-snapshot

Genetically modified mesenchymal stromal cells in cancer therapy

inferred← citeshttps://doi.org/10.1016/j.jcyt.2016.09.007openalex-snapshot

Mesenchymal stromal/stem cells in drug therapy: New perspective

inferred← citeshttps://doi.org/10.1016/j.jcyt.2018.05.011openalex-snapshot

Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery

inferred← citeshttps://doi.org/10.1016/j.jcyt.2020.04.102openalex-snapshot

Splenic macrophage phagocytosis of intravenously infused mesenchymal stromal cells attenuates tumor localization

inferred← citeshttps://doi.org/10.1016/j.jcyt.2021.12.005openalex-snapshot

Pancreatic cancer growth promoted by bone marrow mesenchymal stromal cell–derived IL-6 is reversed predominantly by IL-6 blockade

inferred← citeshttps://doi.org/10.1016/j.jddst.2024.106315openalex-snapshot

Anti-tumor effects of ellagic acid and mesenchymal stem cell-conditioned medium on breast cancer cells on the 3D printed PCL/agarose scaffolds

inferred← citeshttps://doi.org/10.1016/j.jss.2010.07.019openalex-snapshot

The Immunomodulatory Properties of Mesenchymal Stem Cells: Implications for Surgical Disease

inferred← citeshttps://doi.org/10.1016/j.jss.2014.02.047openalex-snapshot

Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti–high mobility group box 1 activity: targeting of colon cancer

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