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T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Evolution of Glutathione Metabolism
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IL‐2 gene expression and NF‐kappa B activation through CD28 requires reactive oxygen production by 5‐lipoxygenase.
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Reduction of HDL- and LDL-Associated Cholesterylester and Phospholipid Hydroperoxides by Phospholipid Hydroperoxide Glutathione Peroxidase and Ebselen (PZ-51)
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Persistent oxidative stress in cancer
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Comparison between the effects of normoxia and hypoxia on antioxidant enzymes and glutathione redox state in ex vivo culture of CD34+ cells
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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
inferredcites →https://doi.org/10.1016/j.cell.2009.07.006openalex-snapshot
RIP Kinases at the Crossroads of Cell Death and Survival
inferredcites →https://doi.org/10.1016/j.cell.2012.03.042openalex-snapshot
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
inferredcites →https://doi.org/10.1016/j.cell.2013.12.010openalex-snapshot
Regulation of Ferroptotic Cancer Cell Death by GPX4
inferredcites →https://doi.org/10.1016/j.cellsig.2012.01.008openalex-snapshot
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
inferredcites →https://doi.org/10.1016/j.cmet.2008.07.005openalex-snapshot
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
inferredcites →https://doi.org/10.1016/j.immuni.2011.12.007openalex-snapshot
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
inferredcites →https://doi.org/10.1016/j.immuni.2012.10.020openalex-snapshot
Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
inferredcites →https://doi.org/10.1016/j.immuni.2013.04.005openalex-snapshot
Metabolic Pathways in Immune Cell Activation and Quiescence
inferredcites →https://doi.org/10.1016/s0021-9258(19)40252-4openalex-snapshot
Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides.
inferredcites →https://doi.org/10.1016/s0300-483x(02)00448-1openalex-snapshot
Oxy radicals, lipid peroxidation and DNA damage
inferredcites →https://doi.org/10.1016/s0891-5849(02)01360-6openalex-snapshot
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
inferredcites →https://doi.org/10.1016/s0891-5849(03)00101-1openalex-snapshot
Coxsackievirus B3-resistant mice become susceptible in Se/vitamin E deficiency
inferredcites →https://doi.org/10.1016/s1074-7613(00)80147-8openalex-snapshot
Attrition of T Cell Memory
inferredcites →https://doi.org/10.1016/s1074-7613(00)80515-4openalex-snapshot
Targeted Complementation of MHC Class II Deficiency by Intrathymic Delivery of Recombinant Adenoviruses
inferredcites →https://doi.org/10.1016/s1074-7613(00)80549-xopenalex-snapshot
A Role for FADD in T Cell Activation and Development
inferredcites →https://doi.org/10.1016/s1074-7613(01)00227-8openalex-snapshot
A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival
inferredcites →https://doi.org/10.1038/342559a0openalex-snapshot
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
inferredcites →https://doi.org/10.1038/414813aopenalex-snapshot
Biochemistry and molecular cell biology of diabetic complications
inferredcites →https://doi.org/10.1038/nature05292openalex-snapshot
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
inferredcites →https://doi.org/10.1038/nature05859openalex-snapshot
RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
inferredcites →https://doi.org/10.1038/nchembio.85openalex-snapshot
Reconciling the chemistry and biology of reactive oxygen species
inferredcites →https://doi.org/10.1038/nchembio711openalex-snapshot
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
inferredcites →https://doi.org/10.1038/ni.2386openalex-snapshot
Metabolic checkpoints in activated T cells
inferredcites →https://doi.org/10.1038/ni1096openalex-snapshot
T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
inferredcites →https://doi.org/10.1038/nrm2256openalex-snapshot
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
inferredcites →https://doi.org/10.1038/srep00266openalex-snapshot
Activated human CD4+ T cells express transporters for both cysteine and cystine
inferredcites →https://doi.org/10.1073/pnas.022630299openalex-snapshot
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation
inferredcites →https://doi.org/10.1073/pnas.94.13.6874openalex-snapshot
A critical role for neutralizing-antibody-producing B cells, CD4 + T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
inferredcites →https://doi.org/10.1074/jbc.271.39.24055openalex-snapshot
Disruption of 12/15-Lipoxygenase Expression in Peritoneal Macrophages
inferredcites →https://doi.org/10.1083/jcb.201102095openalex-snapshot
Signal transduction by reactive oxygen species
inferredcites →https://doi.org/10.1084/jem.20010659openalex-snapshot
Discrete Generation of Superoxide and Hydrogen Peroxide by T Cell Receptor Stimulation
inferredcites →https://doi.org/10.1084/jem.20110251openalex-snapshot
Mechanisms of necroptosis in T cells
inferredcites →https://doi.org/10.1089/ars.2006.8.1549openalex-snapshot
Role of Nox Family NADPH Oxidases in Host Defense
inferredcites →https://doi.org/10.1093/ndt/gft142openalex-snapshot
Immune and inflammatory mechanisms
inferredcites →https://doi.org/10.1096/fasebj.12.15.1665openalex-snapshot
Vitamin E and selenium deficiency induces expression of the ubiquinone‐dependent antioxidant system at the plasma membrane
inferredcites →https://doi.org/10.1111/j.1365-2567.2007.02621.xopenalex-snapshot
Expression of 5‐lipoxygenase (5‐LOX) in T lymphocytes
inferredcites →https://doi.org/10.1111/j.1474-9726.2007.00312.xopenalex-snapshot
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms
inferredcites →https://doi.org/10.1111/j.1749-6632.1972.tb27851.xopenalex-snapshot
VITAMIN E AND FREE RADICAL PEROXIDATION OF LIPIDS*
inferredcites →https://doi.org/10.1126/science.276.5321.2057openalex-snapshot
Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells
inferredcites →https://doi.org/10.1126/science.281.5381.1305openalex-snapshot
Death Receptors: Signaling and Modulation
inferredcites →https://doi.org/10.1128/mcb.24.4.1464-1469.2004openalex-snapshot
Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4
inferredcites →https://doi.org/10.1146/annurev-immunol-032712-095956openalex-snapshot
Metabolic Regulation of T Lymphocytes
inferredcites →https://doi.org/10.1146/annurev.immunol.021908.132620openalex-snapshot
Immune and Inflammatory Mechanisms of Atherosclerosis
inferredcites →https://doi.org/10.1146/annurev.immunol.021908.132706openalex-snapshot
T Cell Activation
inferredcites →https://doi.org/10.1152/physiolgenomics.00019.2007openalex-snapshot
Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues
inferredcites →https://doi.org/10.1182/blood-2010-09-307041openalex-snapshot
Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress
inferredcites →https://doi.org/10.1246/bcsj.58.1971openalex-snapshot
Oxidation of Lipids. VIII. Synergistic Inhibition of Oxidation of Phosphatidylcholine Liposome in Aqueous Dispersion by Vitamin E and Vitamin C
inferredcites →https://doi.org/10.1593/neo.91782openalex-snapshot
Absence of Glutathione Peroxidase 4 Affects Tumor Angiogenesis through Increased 12/15-Lipoxygenase Activity
inferredcites →https://doi.org/10.4049/jimmunol.0903586openalex-snapshot
Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation
inferredcites →https://doi.org/10.4049/jimmunol.177.2.852openalex-snapshot
Electron Transport Complex I Is Required for CD8+ T Cell Function
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4352898openalex-extracted
Suppressing Ferroptosis Decreases the Multiplication of Mycobacterium Marinum in Human Macrophages
inferred← citeshttps://doi.org/10.1002/adbi.202100396openalex-snapshot
Lipid Metabolism in Ferroptosis
inferred← citeshttps://doi.org/10.1002/adbi.202500460openalex-snapshot
Targeting Ferroptosis in Nasopharyngeal Carcinoma: Mechanisms of Therapy Resistance and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1002/adma.201704007openalex-snapshot
Emerging Strategies of Cancer Therapy Based on Ferroptosis
inferred← citeshttps://doi.org/10.1002/adma.201905823openalex-snapshot
Manganese Oxide Nanomaterials: Synthesis, Properties, and Theranostic Applications
inferred← citeshttps://doi.org/10.1002/advs.202204514openalex-snapshot
Ferroptosis Signature Shapes the Immune Profiles to Enhance the Response to Immune Checkpoint Inhibitors in Head and Neck Cancer
inferred← citeshttps://doi.org/10.1002/advs.75651openalex-snapshot
T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions
inferred← citeshttps://doi.org/10.1002/ajh.26001openalex-snapshot
Cell‐type‐specific insights into iron regulatory processes
inferred← citeshttps://doi.org/10.1002/ange.202300379openalex-snapshot
Ferroptosis Detection: From Approaches to Applications
inferred← citeshttps://doi.org/10.1002/anie.202300379openalex-snapshot
Ferroptosis Detection: From Approaches to Applications
inferred← citeshttps://doi.org/10.1002/ardp.202500010openalex-snapshot
Advances in the Development of Ferroptosis‐Inducing Agents for Cancer Treatment
inferred← citeshttps://doi.org/10.1002/biof.2015openalex-snapshot
Endogenous chemicals guard health through inhibiting ferroptotic cell death
inferred← citeshttps://doi.org/10.1002/cac2.70064openalex-snapshot
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
inferred← citeshttps://doi.org/10.1002/ctm2.70253openalex-snapshot
Ferroptosis of T cell in inflammation and tumour immunity
inferred← citeshttps://doi.org/10.1002/eji.201646342openalex-snapshot
Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice
inferred← citeshttps://doi.org/10.1002/eji.202049114openalex-snapshot
Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis
inferred← citeshttps://doi.org/10.1002/eji.202350836openalex-snapshot
Trappc1 intrinsically prevents ferroptosis of naive T cells to avoid spontaneous autoinflammatory disease in mice
inferred← citeshttps://doi.org/10.1002/hep.28574openalex-snapshot
Metallothionein‐1G facilitates sorafenib resistance through inhibition of ferroptosis
inferred← citeshttps://doi.org/10.1002/iub.1616openalex-snapshot
Iron and ferroptosis: A still ill‐defined liaison
inferred← citeshttps://doi.org/10.1002/jcp.29232openalex-snapshot
Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin
inferred← citeshttps://doi.org/10.1002/jmv.28386openalex-snapshot
Transcriptomic reveals the ferroptosis features of host response in a mouse model of Zika virus infection
inferred← citeshttps://doi.org/10.1002/mco2.70268openalex-snapshot
Oxidative Stress: Signaling Pathways, Biological Functions, and Disease
inferred← citeshttps://doi.org/10.1002/mco2.70349openalex-snapshot
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
inferred← citeshttps://doi.org/10.1002/mco2.70886openalex-snapshot
Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1002/wnan.2010openalex-snapshot
Biomaterial‐Mediated Metabolic Regulation of Ferroptosis for Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/wsbm.70009openalex-snapshot
Friend or Foe? The Dual Role of Ferroptosis in Tumor Immunity and Immunotherapy
inferred← citeshttps://doi.org/10.1007/82_2016_508openalex-snapshot
Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-1-0716-0247-8_11openalex-snapshot
Detection of Ferroptosis by BODIPY™ 581/591 C11
inferred← citeshttps://doi.org/10.1007/978-1-4939-9210-2_18openalex-snapshot
Experimental Cutaneous Leishmaniasis: Mouse Models for Resolution of Inflammation Versus Chronicity of Disease
inferred← citeshttps://doi.org/10.1007/978-3-030-26780-3_15openalex-snapshot
Ferroptosis in Hemolytic Disorders
inferred← citeshttps://doi.org/10.1007/978-3-030-26780-3_4openalex-snapshot
Heat Shock Proteins: Endogenous Modulators of Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-3-030-62026-4_5openalex-snapshot
Emerging Role for Ferroptosis in Infectious Diseases
inferred← citeshttps://doi.org/10.1007/978-3-030-62026-4_6openalex-snapshot
Small Molecule Regulators of Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-3-031-39171-2_1openalex-snapshot
Lipid Metabolism and Homeostasis in Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-3-031-39171-2_16openalex-snapshot
Ferroptosis and Infectious Diseases
inferred← citeshttps://doi.org/10.1007/978-3-032-12166-0_16openalex-snapshot
Fueling Death: The Metabolic Control of Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_17openalex-snapshot
Basics and News on Glutathione Peroxidases
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_43openalex-snapshot
Glutathione Peroxidase 4 and Ferroptosis
inferred← citeshttps://doi.org/10.1007/978-3-319-95390-8_6openalex-snapshot
Oxidative Stress, Selenium Redox Systems Including GPX/TXNRD Families
inferred← citeshttps://doi.org/10.1007/978-981-16-1247-3_145-1openalex-snapshot
Reactive Oxygen Species in Glioma
inferred← citeshttps://doi.org/10.1007/978-981-16-5422-0_145openalex-snapshot
Reactive Oxygen Species in Glioma
inferred← citeshttps://doi.org/10.1007/s00109-023-02361-0openalex-snapshot
The plasma exosomes from patients with primary Sjögren’s syndrome contain epithelial cell–derived proteins involved in ferroptosis
inferred← citeshttps://doi.org/10.1007/s00204-023-03625-xopenalex-snapshot
Ferroptosis: potential targets and emerging roles in pancreatic diseases
inferred← citeshttps://doi.org/10.1007/s00262-025-04133-wopenalex-snapshot
GPX4 is a key ferroptosis regulator orchestrating T cells and CAR-T-cells sensitivity to ferroptosis
inferred← citeshttps://doi.org/10.1007/s00394-022-02940-wopenalex-snapshot
Free docosahexaenoic acid promotes ferroptotic cell death via lipoxygenase dependent and independent pathways in cancer cells
inferred← citeshttps://doi.org/10.1007/s10067-024-07007-1openalex-snapshot
miR-141-3p attenuates RSL3-induced ferroptosis and intestinal epithelial-mesenchymal transition via directly inhabits ZEB1 in intestinal Behçet’s syndrome
inferred← citeshttps://doi.org/10.1007/s10142-026-01918-9openalex-snapshot
Integrative multi-omics analysis and machine learning identify M2 macrophage–induced ferroptosis resistance in glioblastoma
inferred← citeshttps://doi.org/10.1007/s10238-025-01766-0openalex-snapshot
MicroRNAs at the crossroads of exercise and ferroptosis: a regulatory bridge
inferred← citeshttps://doi.org/10.1007/s10238-026-02192-6openalex-snapshot
Zinc supplementation ameliorates colitis in mice by sensitizing pathogenic CD4+ T cells to ferroptosis
inferred← citeshttps://doi.org/10.1007/s10522-016-9642-zopenalex-snapshot
Is immunosenescence influenced by our lifetime “dose” of exercise?
inferred← citeshttps://doi.org/10.1007/s10565-025-10028-4openalex-snapshot
U2AF65 mediated circPVT1 promotes NSCLC cell proliferation and inhibits ferroptosis through the miR-338-3p/GPX4 axis
inferred← citeshttps://doi.org/10.1007/s10753-025-02356-8openalex-snapshot
Non-apoptotic Regulated Cell Death Mechanisms in Sepsis and their Therapeutic Potential
inferred← citeshttps://doi.org/10.1007/s10787-023-01183-3openalex-snapshot
Nutritional deficiencies that may predispose to long COVID
inferred← citeshttps://doi.org/10.1007/s11010-023-04694-3openalex-snapshot
Emerging roles and therapeutic potentials of ferroptosis: from the perspective of 11 human body organ systems
inferred← citeshttps://doi.org/10.1007/s11033-025-11312-6openalex-snapshot
Sepsis-associated immunosuppression: mechanistic Insights, Biomarkers, and therapeutic perspectives
inferred← citeshttps://doi.org/10.1007/s11427-022-2340-4openalex-snapshot
Nanomedicine targeting ferroptosis to overcome anticancer therapeutic resistance
inferred← citeshttps://doi.org/10.1007/s11686-026-01343-9openalex-snapshot
Deferiprone Modulates Ferroptosis to Protect Macrophages and Liver during Neospora caninum Infection
inferred← citeshttps://doi.org/10.1007/s11739-025-04016-zopenalex-snapshot
Associations between serum levels of ferroptosis-related molecules and outcomes in stable COPD: an exploratory prospective observational study
inferred← citeshttps://doi.org/10.1007/s12011-022-03122-9openalex-snapshot
Interaction of Antioxidant Trace Minerals Affecting Blood Picture Including Antioxidant Profile of Healthy Buffalo (Bubalus bubalis) Calves
inferred← citeshttps://doi.org/10.1007/s12672-025-01911-xopenalex-snapshot
Advances in understanding ferroptosis mechanisms and their impact on immune cell regulation and tumour immunotherapy
inferred← citeshttps://doi.org/10.1007/s12672-025-02592-2openalex-snapshot
Specific signaling pathways mediated programmed cell death in tumor microenvironment and target therapies
inferred← citeshttps://doi.org/10.1007/s13311-021-01111-9openalex-snapshot
Characterization of Selenium Compounds for Anti-ferroptotic Activity in Neuronal Cells and After Cerebral Ischemia–Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s13402-023-00804-xopenalex-snapshot
Gallium maltolate shows synergism with cisplatin and activates nucleolar stress and ferroptosis in human breast carcinoma cells
inferred← citeshttps://doi.org/10.1007/s40139-017-0139-5openalex-snapshot
Autophagy and Ferroptosis—What Is the Connection?
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.64220-4openalex-snapshot
Cell Injury and Necrosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.95621-6openalex-snapshot
Glutathione Peroxidases
inferred← citeshttps://doi.org/10.1016/b978-0-12-817558-3.00008-1openalex-snapshot
Mitigating viral invasion: mTORC2’s role in neuroprotection and immunity
inferred← citeshttps://doi.org/10.1016/b978-0-12-818606-0.00010-9openalex-snapshot
Ferroptosis: Physiological and pathophysiological aspects
inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00009-7openalex-snapshot
Glutathione Peroxidases
inferred← citeshttps://doi.org/10.1016/b978-0-443-15447-8.00008-8openalex-snapshot
Adaptive immunity and metabolism
inferred← citeshttps://doi.org/10.1016/bs.acr.2017.07.004openalex-snapshot
Selenium-Dependent Glutathione Peroxidases During Tumor Development
inferred← citeshttps://doi.org/10.1016/bs.acr.2024.05.003openalex-snapshot
Role of antioxidants in modulating anti-tumor T cell immune resposne
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2018.07.004openalex-snapshot
T Cells and Regulated Cell Death
inferred← citeshttps://doi.org/10.1016/bs.mcb.2026.05.017openalex-snapshot
Lipid ROS measurement by spectral flow cytometry based on the ratiometric dye BODIPY™ C11 581/591
inferred← citeshttps://doi.org/10.1016/j.abb.2026.110760openalex-snapshot
Unlocking ferroptosis: A novel link between triple-negative breast cancer and immune regulation
inferred← citeshttps://doi.org/10.1016/j.aca.2023.341571openalex-snapshot
A D-π-A-π-D type structure-based fluorescent probe for revealing the fluctuations of the ER polarity during ferroptosis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2019.09.011openalex-snapshot
Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation–Mediated Cell Death in Mice
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2026.743825openalex-snapshot
Red Sea bream iridovirus (RSIV) infection elicits cell death modes—Apoptosis and ferroptosis in silver Pomfret (Pampus argenteus)
inferred← citeshttps://doi.org/10.1016/j.aquatox.2024.107078openalex-snapshot
LC-MS untargeted metabolomics reveals metabolic disturbance and ferroptosis in MWCNTs-induced hepatotoxicity of Cyprinus carpio
inferred← citeshttps://doi.org/10.1016/j.arr.2020.101206openalex-snapshot
Nrf2: a dark horse in Alzheimer's disease treatment
inferred← citeshttps://doi.org/10.1016/j.arr.2026.103035openalex-snapshot
Targeting the Nrf2/HO-1 aixs: A therapeutic strategy against regulated cell death in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.arres.2026.100156openalex-snapshot
Ferroptosis in gut pathophysiology: Molecular mechanisms and microbial regulation of iron metabolism and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.autrev.2024.103640openalex-snapshot
Targeting ferroptosis in autoimmune diseases: Mechanisms and therapeutic prospects
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188848openalex-snapshot
Ferroptosis and its interaction with tumor immune microenvironment in liver cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.188890openalex-snapshot
GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment
inferred← citeshttps://doi.org/10.1016/j.bbcan.2026.189646openalex-snapshot
Ferroptosis in the tumor immune microenvironment: A double-edged sword in immunotherapy
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.03.052openalex-snapshot
Identification of baicalein as a ferroptosis inhibitor by natural product library screening
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.08.034openalex-snapshot
CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.08.124openalex-snapshot
Identification of ACSL4 as a biomarker and contributor of ferroptosis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.07.100openalex-snapshot
The ferroptosis inducer erastin promotes proliferation and differentiation in human peripheral blood mononuclear cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.08.082openalex-snapshot
PPARG-mediated ferroptosis in dendritic cells limits antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.12.034openalex-snapshot
GPX4 aggravates experimental autoimmune encephalomyelitis by inhibiting the functions of CD4+ T cells
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114584openalex-snapshot
Recent progress on targeting ferroptosis for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.118410openalex-snapshot
CRISPR screens for the discovery of novel ferroptosis targets: progress and perspectives
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113279openalex-snapshot
Ferroptosis and its role in cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113516openalex-snapshot
Ferroptosis, novel therapeutics in asthma
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114245openalex-snapshot
Salidroside facilitates therapeutic angiogenesis in diabetic hindlimb ischemia by inhibiting ferroptosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116667openalex-snapshot
Targeting regulated cell death (RCD) in hematological malignancies: Recent advances and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116722openalex-snapshot
Ferroptosis in ulcerative colitis: Potential mechanisms and promising therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116777openalex-snapshot
Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116971openalex-snapshot
Ferroptosis in thyroid cancer: Potential mechanisms, effective therapeutic targets and predictive biomarker
inferred← citeshttps://doi.org/10.1016/j.brainres.2026.150514openalex-snapshot
Ferroptosis and Alzheimer’s disease: Neuroimmune crosstalk and pharmacological opportunities
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216152openalex-snapshot
Ferroptosis: Promising approach for cancer and cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.217115openalex-snapshot
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor
inferred← citeshttps://doi.org/10.1016/j.ccell.2017.11.004openalex-snapshot
Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
inferred← citeshttps://doi.org/10.1016/j.ccell.2022.03.003openalex-snapshot
CD8+ T cells PUF(A)ing the flames of cancer ferroptotic cell death
inferred← citeshttps://doi.org/10.1016/j.ccell.2024.03.011openalex-snapshot
The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions
inferred← citeshttps://doi.org/10.1016/j.ccell.2026.03.022openalex-snapshot
Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage
inferred← citeshttps://doi.org/10.1016/j.cell.2026.04.049openalex-snapshot
Uncovering spatially resolved functional genomics with CRISPR screen sequencing
inferred← citeshttps://doi.org/10.1016/j.cell.2026.09.024openalex-snapshot
A non-canonical function of glutathione to suppress ferroptosis via FSP1
inferred← citeshttps://doi.org/10.1016/j.cellimm.2023.104774openalex-snapshot
Ferroptosis in the post-transplantation inflammatory response
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.112196openalex-snapshot
CDS1 deficiency promotes colorectal cancer progression by suppressing CDP-DAG-induced ferroptosis in MDSCs
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.112293openalex-snapshot
Role of ferroptosis in gastric cancer
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.12.022openalex-snapshot
c-FLIP Expression in Foxp3-Expressing Cells Is Essential for Survival of Regulatory T Cells and Prevention of Autoimmunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.07.055openalex-snapshot
The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.10.070openalex-snapshot
B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109235openalex-snapshot
The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114636openalex-snapshot
Inherent preference for polyunsaturated fatty acids instigates ferroptosis of Treg cells that aggravates high-fat-diet-related colitis
inferred← citeshttps://doi.org/10.1016/j.chembiol.2020.02.005openalex-snapshot
Autophagy-Dependent Ferroptosis: Machinery and Regulation
inferred← citeshttps://doi.org/10.1016/j.chembiol.2020.03.012openalex-snapshot
Selenium: Tracing Another Essential Element of Ferroptotic Cell Death
inferred← citeshttps://doi.org/10.1016/j.chembiol.2020.03.015openalex-snapshot
Progress in Understanding Ferroptosis and Challenges in Its Targeting for Therapeutic Benefit
inferred← citeshttps://doi.org/10.1016/j.chembiol.2025.11.013openalex-snapshot
Redundant or resilient? A systems view of ferroptosis surveillance mechanisms
inferred← citeshttps://doi.org/10.1016/j.chom.2018.05.009openalex-snapshot
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
inferred← citeshttps://doi.org/10.1016/j.clim.2024.110181openalex-snapshot
Functional consequence of Iron dyshomeostasis and ferroptosis in systemic lupus erythematosus and lupus nephritis
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.06.010openalex-snapshot
Amino Assets: How Amino Acids Support Immunity
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.10.011openalex-snapshot
The Metabolic Underpinnings of Ferroptosis
inferred← citeshttps://doi.org/10.1016/j.cmet.2021.02.015openalex-snapshot
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
inferred← citeshttps://doi.org/10.1016/j.cmet.2023.06.003openalex-snapshot
Beggars banquet: Metabolism in the tumor immune microenvironment and cancer therapy
inferred← citeshttps://doi.org/10.1016/j.cmet.2023.09.004openalex-snapshot
Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
inferred← citeshttps://doi.org/10.1016/j.cmet.2024.01.006openalex-snapshot
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
inferred← citeshttps://doi.org/10.1016/j.cmet.2026.06.002openalex-snapshot
Reactive species as regulators of immune cell metabolism, tolerance, and autoimmunity
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2024.104359openalex-snapshot
The new era of lung cancer therapy: Combining immunotherapy with ferroptosis
inferred← citeshttps://doi.org/10.1016/j.cub.2018.05.094openalex-snapshot
AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2023.08.004openalex-snapshot
Ferroptosis in cancer immunity and immunotherapy: Multifaceted interplay and clinical implications
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2025.06.007openalex-snapshot
Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.06.019openalex-snapshot
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2020.110360openalex-snapshot
Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112842openalex-snapshot
Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116721openalex-snapshot
GPX4 allosteric activators inhibit ferroptosis and exert myocardial protection in doxorubicin-induced myocardial injury mouse model
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.118880openalex-snapshot
Discovery of Trolox amide derivatives as potent membrane-targeted ferroptosis inhibitors for corneal injury therapy
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174319openalex-snapshot
Ferroptosis as a new therapeutic opportunity for nonviral liver disease
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174518openalex-snapshot
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.175304openalex-snapshot
Identification of a new small molecule that initiates ferroptosis in cancer cells by inhibiting the system Xc− to deplete GSH
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.176124openalex-snapshot
Ferroptosis and tumor immunity: In perspective of the major cell components in the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.178108openalex-snapshot
Astragalin inhibits hepatitis B virus through functional reconstitution of CD8+ T cells and a direct effect on HBV control
inferred← citeshttps://doi.org/10.1016/j.envpol.2024.125240openalex-snapshot
Interactions between blood lead (Pb) concentration, oxidative stress, cellular immune response and reproductive status in livestock from a mining area
inferred← citeshttps://doi.org/10.1016/j.exger.2025.112974openalex-snapshot
The interplay between the immune microenvironment and bone aging: From molecular mechanisms to therapeutic interventions
inferred← citeshttps://doi.org/10.1016/j.exphem.2025.105346openalex-snapshot
Emerging paradigms in redox regulation: the role of selenoproteins in normal and malignant hematopoiesis
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.108174openalex-snapshot
Comparative effects of different molecular forms of eicosapentaenoic acid in ameliorating 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease via inhibition of ferroptosis in C57BL/6 mice
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.03.001openalex-snapshot
Selenium and GPX4, a vital symbiosis
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.05.074openalex-snapshot
The tumor suppressor protein p53 and the ferroptosis network
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.09.014openalex-snapshot
Role of GPX4 in ferroptosis and its pharmacological implication
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.09.033openalex-snapshot
Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.09.043openalex-snapshot
The development of the concept of ferroptosis
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.01.013openalex-snapshot
Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.10.008openalex-snapshot
Different functions of vitamin E homologues in the various types of cell death induced by oxysterols
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.10.029openalex-snapshot
Vitamin E research: Past, now and future
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.06.227openalex-snapshot
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later
inferred← citeshttps://doi.org/10.1016/j.fsi.2020.09.036openalex-snapshot
Escherichia coli induced ferroptosis in red blood cells of grass carp (Ctenopharyngodon idella)
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e27194openalex-snapshot
Discovering ferroptosis-associated tumor antigens and ferroptosis subtypes in pancreatic adenocarcinoma to facilitate mRNA vaccine development
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.135147openalex-snapshot
Bioactive polysaccharides mediate ferroptosis to modulate tumor immunotherapy
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.140523openalex-snapshot
Cross-talks of GSH, mitochondria, RNA m6A modification, NRF2, and p53 between ferroptosis and cuproptosis in HCC: A review
inferred← citeshttps://doi.org/10.1016/j.immuni.2017.03.019openalex-snapshot
Glutathione Primes T Cell Metabolism for Inflammation
inferred← citeshttps://doi.org/10.1016/j.immuni.2021.05.003openalex-snapshot
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
inferred← citeshttps://doi.org/10.1016/j.immuni.2021.07.004openalex-snapshot
Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease
inferred← citeshttps://doi.org/10.1016/j.immuni.2023.01.023openalex-snapshot
Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes
inferred← citeshttps://doi.org/10.1016/j.immuni.2024.03.019openalex-snapshot
Ironing out the role of ferroptosis in immunity
inferred← citeshttps://doi.org/10.1016/j.immuni.2024.04.017openalex-snapshot
CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.07.012openalex-snapshot
Mitochondria reactive oxygen species signaling in immune responses
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.11.018openalex-snapshot
Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.109707openalex-snapshot
Evaluation of genetic variants in ferroptosis-related genes and house dust mite-induced allergic rhinitis risk
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110810openalex-snapshot
Metronomic capecitabine with rapamycin exerts an immunosuppressive effect by inducing ferroptosis of CD4+ T cells after liver transplantation in rat
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111377openalex-snapshot
CD4 + T cells ferroptosis is associated with the development of sepsis in severe polytrauma patients
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112203openalex-snapshot
Ferroptosis in antitumor therapy: Unraveling regulatory mechanisms and immunogenic potential
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112433openalex-snapshot
Tumor microenvironment characteristics of lipid metabolism reprogramming related to ferroptosis and EndMT influencing prognosis in gastric cancer
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112819openalex-snapshot
Advances in the study of ferroptosis and its relationship to autoimmune diseases
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114042openalex-snapshot
Genetic analysis of diagnostic and therapeutic potential for ferroptosis in postoperative sepsis
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114320openalex-snapshot
CD4+ T-cell metabolism in the pathogenesis of Sjogren's syndrome
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115876openalex-snapshot
Amino acid transporter SLC7A11 functions in ferroptosis regulation and immune microenvironment in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.isci.2020.101302openalex-snapshot
Systematic Analysis of the Aberrances and Functional Implications of Ferroptosis in Cancer
inferred← citeshttps://doi.org/10.1016/j.isci.2020.101499openalex-snapshot
Chemically Programmed Vaccines: Iron Catalysis in Nanoparticles Enhances Combination Immunotherapy and Immunotherapy-Promoted Tumor Ferroptosis
inferred← citeshttps://doi.org/10.1016/j.isci.2021.102431openalex-snapshot
Apoferritin improves motor deficits in MPTP-treated mice by regulating brain iron metabolism and ferroptosis
inferred← citeshttps://doi.org/10.1016/j.it.2022.02.002openalex-snapshot
Context-dependent regulation of follicular helper T cell survival
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.101617openalex-snapshot
Metabolic regulation of ferroptosis in the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.09.008openalex-snapshot
Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2025.101612openalex-snapshot
Targeting Ferroptosis Restores the Antiviral Activity of CD8+ T Cells During Chronic Hepatitis B Virus Infection
inferred← citeshttps://doi.org/10.1016/j.jcrc.2026.155696openalex-snapshot
Cell death mechanisms in sepsis-associated adaptive immune dysfunction
inferred← citeshttps://doi.org/10.1016/j.jid.2025.06.1289openalex-snapshot
Emerging Roles of Ferroptosis in Skin Pathophysiology
inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100765openalex-snapshot
Do physiological changes in fatty acid composition alter cellular ferroptosis susceptibility and influence cell function?
inferred← citeshttps://doi.org/10.1016/j.jtemb.2018.08.008openalex-snapshot
Selenium and copper interaction at supra-nutritional level affecting blood parameters including immune response against P. multocida antigen in Murrah buffalo (Bubalus bubalis) calves
inferred← citeshttps://doi.org/10.1016/j.jtemb.2025.127766openalex-snapshot
Ferroptosis and iron homeostasis in chronic obstructive pulmonary disease: Therapeutic opportunities of iron chelators
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119958openalex-snapshot
Cashing in on ferroptosis against tumor cells: Usher in the next chapter
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120868openalex-snapshot
Focus on ferroptosis regulation: Exploring novel mechanisms and applications of ferroptosis regulator
inferred← citeshttps://doi.org/10.1016/j.livsci.2019.04.019openalex-snapshot
Supra-nutritional copper influences blood parameters including antioxidant markers and immune response in Murrah buffalo (Bubalus bubalis) calves
inferred← citeshttps://doi.org/10.1016/j.lmd.2026.100128openalex-snapshot
Diet sets the ferroptosis threshold of T cells
inferred← citeshttps://doi.org/10.1016/j.lwt.2023.115235openalex-snapshot
Assessment of antioxidant bioactive properties of iberian dry-cured ham fat-derived essences using the yeast Saccharomyces cerevisiae as experimental model
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