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The transcriptional program, functional heterogeneity, and clinical targeting of mast cells

https://doi.org/10.1084/jem.20170910

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Omalizumab for asthma in adults and children

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Key regulators control distinct transcriptional programmes in blood progenitor and mast cells

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Adipose Tissue as a Dedicated Reservoir of Functional Mast Cell Progenitors

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Evidence that Meningeal Mast Cells Can Worsen Stroke Pathology in Mice

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Mast cells and IgE in defense against venoms: Possible “good side” of allergy?

inferredcites →https://doi.org/10.1016/j.aller.2014.05.002openalex-snapshot

Clinical characteristics and risk profile of patients with elevated baseline serum tryptase

inferredcites →https://doi.org/10.1016/j.bbadis.2010.12.024openalex-snapshot

Mast cell transcription factors—Regulators of cell fate and phenotype

inferredcites →https://doi.org/10.1016/j.cell.2008.05.050openalex-snapshot

Phosphorylation of SNAP-23 by IκB Kinase 2 Regulates Mast Cell Degranulation

inferredcites →https://doi.org/10.1016/j.celrep.2013.12.029openalex-snapshot

Critical Role for Mast Cell Stat5 Activity in Skin Inflammation

inferredcites →https://doi.org/10.1016/j.celrep.2014.07.046openalex-snapshot

IκB Kinase 2 Is Essential for IgE-Induced Mast Cell De Novo Cytokine Production but Not for Degranulation

inferredcites →https://doi.org/10.1016/j.celrep.2016.04.044openalex-snapshot

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities

inferredcites →https://doi.org/10.1016/j.cmet.2015.04.013openalex-snapshot

Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance

inferredcites →https://doi.org/10.1016/j.immuni.2011.03.028openalex-snapshot

Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

inferredcites →https://doi.org/10.1016/j.immuni.2011.09.015openalex-snapshot

Cre-Mediated Cell Ablation Contests Mast Cell Contribution in Models of Antibody- and T Cell-Mediated Autoimmunity

inferredcites →https://doi.org/10.1016/j.immuni.2012.09.022openalex-snapshot

Perivascular Mast Cells Dynamically Probe Cutaneous Blood Vessels to Capture Immunoglobulin E

inferredcites →https://doi.org/10.1016/j.immuni.2013.04.007openalex-snapshot

A Truncated Splice-Variant of the FcεRIβ Receptor Subunit Is Critical for Microtubule Formation and Degranulation in Mast Cells

inferredcites →https://doi.org/10.1016/j.immuni.2013.06.012openalex-snapshot

Antagonistic Regulation by the Transcription Factors C/EBPα and MITF Specifies Basophil and Mast Cell Fates

inferredcites →https://doi.org/10.1016/j.immuni.2015.08.020openalex-snapshot

Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy

inferredcites →https://doi.org/10.1016/j.immuni.2016.11.003openalex-snapshot

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules

inferredcites →https://doi.org/10.1016/j.immuni.2017.04.017openalex-snapshot

Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections

inferredcites →https://doi.org/10.1016/j.it.2012.09.008openalex-snapshot

New models for analyzing mast cell functions in vivo

inferredcites →https://doi.org/10.1016/j.jaci.2012.12.1564openalex-snapshot

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

inferredcites →https://doi.org/10.1016/j.jaci.2014.03.031openalex-snapshot

Siglec-7 is an inhibitory receptor on human mast cells and basophils

inferredcites →https://doi.org/10.1016/j.jaci.2014.05.004openalex-snapshot

Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria

inferredcites →https://doi.org/10.1016/j.jaci.2015.09.059openalex-snapshot

IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3

inferredcites →https://doi.org/10.1016/j.jaci.2016.01.049openalex-snapshot

Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis

inferredcites →https://doi.org/10.1016/j.jaci.2016.09.019openalex-snapshot

Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes

inferredcites →https://doi.org/10.1016/j.jaci.2016.09.049openalex-snapshot

IL-33 fine tunes mast cell degranulation and chemokine production at the single-cell level

inferredcites →https://doi.org/10.1016/j.jaci.2016.11.044openalex-snapshot

Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

inferredcites →https://doi.org/10.1016/j.molmed.2006.07.008openalex-snapshot

MITF: master regulator of melanocyte development and melanoma oncogene

inferredcites →https://doi.org/10.1016/j.molmed.2013.05.001openalex-snapshot

Chronic adipose tissue inflammation: all immune cells on the stage

inferredcites →https://doi.org/10.1016/j.molmed.2016.03.002openalex-snapshot

Noncanonical NF-κB Signaling in Health and Disease

inferredcites →https://doi.org/10.1016/j.pharmthera.2012.06.005openalex-snapshot

Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions

inferredcites →https://doi.org/10.1016/s0014-5793(01)02663-1openalex-snapshot

Mice lacking histidine decarboxylase exhibit abnormal mast cells

inferredcites →https://doi.org/10.1016/s0140-6736(15)00388-8openalex-snapshot

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

inferredcites →https://doi.org/10.1016/s0140-6736(16)30307-5openalex-snapshot

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

inferredcites →https://doi.org/10.1038/23488openalex-snapshot

Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

inferredcites →https://doi.org/10.1038/embor.2011.110openalex-snapshot

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

inferredcites →https://doi.org/10.1038/leu.2015.284openalex-snapshot

Additional mutations in SRSF2, ASXL1 and/or RUNX1 identify a high-risk group of patients with KIT D816V+ advanced systemic mastocytosis

inferredcites →https://doi.org/10.1038/nature12655openalex-snapshot

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

inferredcites →https://doi.org/10.1038/nature14022openalex-snapshot

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

inferredcites →https://doi.org/10.1038/nchembio.2334openalex-snapshot

In silico design of novel probes for the atypical opioid receptor MRGPRX2

inferredcites →https://doi.org/10.1038/ncomms13696openalex-snapshot

A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

inferredcites →https://doi.org/10.1038/ng.3696openalex-snapshot

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

inferredcites →https://doi.org/10.1038/ni.1886openalex-snapshot

An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E–mediated immediate hypersensitivity reactions

inferredcites →https://doi.org/10.1038/ni.2065openalex-snapshot

Crosstalk in NF-κB signaling pathways

inferredcites →https://doi.org/10.1038/ni.2109openalex-snapshot

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

inferredcites →https://doi.org/10.1038/ni.2230openalex-snapshot

Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling

inferredcites →https://doi.org/10.1038/ni.2586openalex-snapshot

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis

inferredcites →https://doi.org/10.1038/ni.3412openalex-snapshot

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

inferredcites →https://doi.org/10.1038/ni.3445openalex-snapshot

Expression profiling of constitutive mast cells reveals a unique identity within the immune system

inferredcites →https://doi.org/10.1038/ni.3486openalex-snapshot

The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation

inferredcites →https://doi.org/10.1038/ni768openalex-snapshot

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

inferredcites →https://doi.org/10.1038/nm.2754openalex-snapshot

Therapies for allergic inflammation: refining strategies to induce tolerance

inferredcites →https://doi.org/10.1038/nm.2755openalex-snapshot

IgE and mast cells in allergic disease

inferredcites →https://doi.org/10.1038/nri2782openalex-snapshot

Mast cell-orchestrated immunity to pathogens

inferredcites →https://doi.org/10.1038/nri3427openalex-snapshot

Protective and pathological roles of mast cells and basophils

inferredcites →https://doi.org/10.1038/nri3690openalex-snapshot

Mast cell secretory granules: armed for battle

inferredcites →https://doi.org/10.1042/bsr20140021openalex-snapshot

Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology

inferredcites →https://doi.org/10.1056/nejmoa1403290openalex-snapshot

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

inferredcites →https://doi.org/10.1056/nejmoa1411776openalex-snapshot

Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme

inferredcites →https://doi.org/10.1067/mai.2000.104942openalex-snapshot

Dependence of mast cell IgE-mediated cytokine production on nuclear factor-κB activity

inferredcites →https://doi.org/10.1073/pnas.0801074105openalex-snapshot

Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate

inferredcites →https://doi.org/10.1073/pnas.1111048108openalex-snapshot

Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue

inferredcites →https://doi.org/10.1073/pnas.1112268109openalex-snapshot

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

inferredcites →https://doi.org/10.1073/pnas.1608520113openalex-snapshot

Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy

inferredcites →https://doi.org/10.1073/pnas.1616420114openalex-snapshot

Dnmt3a restrains mast cell inflammatory responses

inferredcites →https://doi.org/10.1074/jbc.m112.358119openalex-snapshot

Genetic Evidence for Critical Roles of P38α Protein in Regulating Mast Cell Differentiation and Chemotaxis through Distinct Mechanisms

inferredcites →https://doi.org/10.1074/jbc.m113.546895openalex-snapshot

Proteolytic Histone Modification by Mast Cell Tryptase, a Serglycin Proteoglycan-dependent Secretory Granule Protease

inferredcites →https://doi.org/10.1074/jbc.m405856200openalex-snapshot

Serglycin Is Essential for Maturation of Mast Cell Secretory Granule

inferredcites →https://doi.org/10.1074/jbc.m610859200openalex-snapshot

The Early Growth Response Factor-1 Is Involved in Stem Cell Factor (SCF)-induced Interleukin 13 Production by Mast Cells, but Is Dispensable for SCF-dependent Mast Cell Growth

inferredcites →https://doi.org/10.1084/jem.20091513openalex-snapshot

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

inferredcites →https://doi.org/10.1084/jem.20150388openalex-snapshot

Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation

inferredcites →https://doi.org/10.1084/jem.20160081openalex-snapshot

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction

inferredcites →https://doi.org/10.1093/intimm/dxs105openalex-snapshot

Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells

inferredcites →https://doi.org/10.1096/fj.10-158378openalex-snapshot

A novel FcεRIβ‐chain truncation regulates human mast cell proliferation and survival

inferredcites →https://doi.org/10.1101/gad.276568.115openalex-snapshot

Role of TET enzymes in DNA methylation, development, and cancer

inferredcites →https://doi.org/10.1111/1753-6405.12325openalex-snapshot

Differences in grass pollen allergen exposure across Australia

inferredcites →https://doi.org/10.1111/j.1365-2222.2006.02443.xopenalex-snapshot

A polymorphism of MS4A2 (−109T>C) encoding the β‐chain of the high‐affinity immunoglobulin E receptor (FcɛR1β) is associated with a susceptibility to aspirin‐intolerant asthma

inferredcites →https://doi.org/10.1126/science.1246976openalex-snapshot

Molecular Editing of Cellular Responses by the High-Affinity Receptor for IgE

inferredcites →https://doi.org/10.1126/scisignal.aag1401openalex-snapshot

Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils

inferredcites →https://doi.org/10.1128/iai.00053-17openalex-snapshot

Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis

inferredcites →https://doi.org/10.1128/mcb.01524-13openalex-snapshot

Transcription Factor GATA1 Is Dispensable for Mast Cell Differentiation in Adult Mice

inferredcites →https://doi.org/10.1128/mcb.25.14.6199-6210.2005openalex-snapshot

Loss of Histochemical Identity in Mast Cells Lacking Carboxypeptidase A

inferredcites →https://doi.org/10.1136/bmjopen-2013-004587openalex-snapshot

Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis

inferredcites →https://doi.org/10.1136/thx.2008.101683openalex-snapshot

Novel site-specific mast cell subpopulations in the human lung

inferredcites →https://doi.org/10.1158/0008-5472.can-16-2234openalex-snapshot

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future

inferredcites →https://doi.org/10.1172/jci73451openalex-snapshot

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

inferredcites →https://doi.org/10.1172/jci75212openalex-snapshot

Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis

inferredcites →https://doi.org/10.1172/jci85538openalex-snapshot

Different activation signals induce distinct mast cell degranulation strategies

inferredcites →https://doi.org/10.1177/0310057x1204000204openalex-snapshot

Histamine-Releasing and Allergenic Properties of Opioid Analgesic Drugs: Resolving the Two

inferredcites →https://doi.org/10.1182/blood-2002-11-3490openalex-snapshot

Stat5 expression is critical for mast cell development and survival

inferredcites →https://doi.org/10.1182/blood-2004-01-0247openalex-snapshot

Roles of MITF for development of mast cells in mice: effects on both precursors and tissue environments

inferredcites →https://doi.org/10.1182/blood-2005-09-3610openalex-snapshot

De novo synthesis of early growth response factor-1 is required for the full responsiveness of mast cells to produce TNF and IL-13 by IgE and antigen stimulation

inferredcites →https://doi.org/10.1182/blood-2009-03-213512openalex-snapshot

A key role for ATF3 in regulating mast cell survival and mediator release

inferredcites →https://doi.org/10.1182/blood-2010-09-309955openalex-snapshot

PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability

inferredcites →https://doi.org/10.1182/blood-2011-03-343962openalex-snapshot

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice

inferredcites →https://doi.org/10.1182/blood-2012-08-453597openalex-snapshot

Aryl hydrocarbon receptor controls murine mast cell homeostasis

inferredcites →https://doi.org/10.1182/blood-2013-02-483792openalex-snapshot

Redefinition of the human mast cell transcriptome by deep-CAGE sequencing

inferredcites →https://doi.org/10.1182/blood-2013-04-496448openalex-snapshot

Comprehensive mutational profiling in advanced systemic mastocytosis

inferredcites →https://doi.org/10.1182/blood-2014-11-612465openalex-snapshot

GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow

inferredcites →https://doi.org/10.1369/0022155412458927openalex-snapshot

Mast Cell Proteoglycans

inferredcites →https://doi.org/10.1371/journal.pone.0043090openalex-snapshot

Single Nucleotide Polymorphism Array Lesions, TET2, DNMT3A, ASXL1 and CBL Mutations Are Present in Systemic Mastocytosis

inferredcites →https://doi.org/10.3324/haematol.2016.146563openalex-snapshot

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

inferredcites →https://doi.org/10.3389/fimmu.2012.00130openalex-snapshot

Cytoskeleton in Mast Cell Signaling

inferredcites →https://doi.org/10.3389/fimmu.2012.00143openalex-snapshot

The SNARE Machinery in Mast Cell Secretion

inferredcites →https://doi.org/10.3389/fimmu.2014.00453openalex-snapshot

Vesicular Trafficking and Signaling for Cytokine and Chemokine Secretion in Mast Cells

inferredcites →https://doi.org/10.3389/fimmu.2016.00524openalex-snapshot

No Role for Mast Cells in Obesity-Related Metabolic Dysregulation

inferredcites →https://doi.org/10.4049/jimmunol.1102660openalex-snapshot

The Transcription Factor Zeb2 Regulates Signaling in Mast Cells

inferredcites →https://doi.org/10.4049/jimmunol.1203158openalex-snapshot

Mast Cell FcεRI-Induced Early Growth Response 2 Regulates CC Chemokine Ligand 1–Dependent CD4+ T Cell Migration

inferredcites →https://doi.org/10.4049/jimmunol.1500018openalex-snapshot

The STAT5–GATA2 Pathway Is Critical in Basophil and Mast Cell Differentiation and Maintenance

inferredcites →https://doi.org/10.4049/jimmunol.161.12.6463openalex-snapshot

Cutting Edge: Impaired Mast Cell Development and Innate Immunity in Mac-1 (CD11b/CD18, CR3)-Deficient Mice

inferredcites →https://doi.org/10.4049/jimmunol.173.4.2571openalex-snapshot

c-Fos as a Regulator of Degranulation and Cytokine Production in FcεRI-Activated Mast Cells

inferredcites →https://doi.org/10.4049/jimmunol.177.10.6667openalex-snapshot

Specific and Redundant Roles for NFAT Transcription Factors in the Expression of Mast Cell-Derived Cytokines

inferredcites →https://doi.org/10.4049/jimmunol.178.1.378openalex-snapshot

Distinct and Shared Transcriptomes Are Regulated by Microphthalmia-Associated Transcription Factor Isoforms in Mast Cells

inferredcites →https://doi.org/10.4193/rhino11.249openalex-snapshot

Steroid resistance in nasal polyposis: role of glucocorticoid receptor and TGF-beta1

inferredcites →https://doi.org/10.4193/rhino11.256openalex-snapshot

Prevalence of chronic rhinosinusitis in Sao Paulo

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Genetic Basis and Clinical Impact of Hereditary Alpha-Tryptasemia

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Endogenous sulfur dioxide is a novel inhibitor of hypoxia-induced mast cell degranulation

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inferred← citeshttps://doi.org/10.1016/j.smim.2022.101606openalex-snapshot

Non-coding RNA-based regulation of inflammation

inferred← citeshttps://doi.org/10.1038/s41467-023-37873-3openalex-snapshot

Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation

inferred← citeshttps://doi.org/10.1038/s41467-023-39614-yopenalex-snapshot

The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells

inferred← citeshttps://doi.org/10.1038/s41467-023-44304-wopenalex-snapshot

Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis

inferred← citeshttps://doi.org/10.1038/s41598-025-07076-5openalex-snapshot

Exploring the association between depression and telomere length: A systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1042/bsr20193220openalex-snapshot

Engineering anti-cancer nanovaccine based on antigen cross-presentation

inferred← citeshttps://doi.org/10.1042/bsr20200256openalex-snapshot

Mechanisms of allergen-specific immunotherapy for allergic rhinitis and food allergies

inferred← citeshttps://doi.org/10.1084/jem.20191169openalex-snapshot

When alpha meets beta, mast cells get hyper

inferred← citeshttps://doi.org/10.1089/ten.tea.2020.0142openalex-snapshot

Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation

inferred← citeshttps://doi.org/10.1097/cmr.0000000000001057openalex-snapshot

Compound 48/80 suppresses melanoma growth by inducing apoptosis and enhancing immune response

inferred← citeshttps://doi.org/10.1097/rli.0000000000000644openalex-snapshot

HLA-DRB1*15:02 Is Associated With Iodinated Contrast Media–Related Anaphylaxis

inferred← citeshttps://doi.org/10.1111/imr.70026openalex-snapshot

Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation

inferred← citeshttps://doi.org/10.1111/jpi.12699openalex-snapshot

The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators

inferred← citeshttps://doi.org/10.1126/sciadv.abb2497openalex-snapshot

ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization

inferred← citeshttps://doi.org/10.1126/science.aat5031openalex-snapshot

Spatiotemporal immune zonation of the human kidney

inferred← citeshttps://doi.org/10.1126/scisignal.adr3411openalex-snapshot

USP5 deubiquitylates and stabilizes FcεRIγ to enhance IgE-induced mast cell activation and allergic inflammation

inferred← citeshttps://doi.org/10.1155/2018/7396136openalex-snapshot

The Mast Cell-Aryl Hydrocarbon Receptor Interplay at the Host-Microbe Interface

inferred← citeshttps://doi.org/10.1155/2019/4204512openalex-snapshot

Type 2 Inflammatory Responses in Autoimmune Demyelination of the Central Nervous System: Recent Advances

inferred← citeshttps://doi.org/10.1159/000500088openalex-snapshot

Physiological Roles of Mast Cells: Collegium Internationale Allergologicum Update 2019

inferred← citeshttps://doi.org/10.1172/jci.insight.125057openalex-snapshot

Targeting tumor-resident mast cells for effective anti-melanoma immune responses

inferred← citeshttps://doi.org/10.12688/f1000research.12384.1openalex-snapshot

Epigenetic and transcriptional control of mast cell responses

inferred← citeshttps://doi.org/10.1371/journal.pone.0190453openalex-snapshot

Mast cell heterogeneity underlies different manifestations of food allergy in mice

inferred← citeshttps://doi.org/10.1371/journal.ppat.1007803openalex-snapshot

Histamine release from intestinal mast cells induced by staphylococcal enterotoxin A (SEA) evokes vomiting reflex in common marmoset

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3070760/v1openalex-snapshot

Mast cell-derived TSLP triggers an allergic response to induce autophagy, thereby inhibiting the development of melanoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3613559/v1openalex-snapshot

Mast Cell-Derived TSLP Triggers an Allergic Response, Thereby Suppressing the Early Stage of Melanoma Development

inferred← citeshttps://doi.org/10.22541/au.170671012.27525086/v1openalex-snapshot

On the role of allergen-specific IgG subclasses for blocking human basophil activation

inferred← citeshttps://doi.org/10.25040/ntsh2023.02.10openalex-snapshot

MAST CELLS IN THE MILIEU: A COMPARATIVE STUDY IN THE TONGUE AND LIVER

inferred← citeshttps://doi.org/10.3389/fcell.2021.630166openalex-snapshot

Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells

inferred← citeshttps://doi.org/10.3389/fcell.2026.1830394openalex-snapshot

Mast cell driven immunometabolism as a therapeutic entry point in ESCC

inferred← citeshttps://doi.org/10.3389/fimmu.2018.01067openalex-snapshot

Effect of Dietary Fiber and Metabolites on Mast Cell Activation and Mast Cell-Associated Diseases

inferred← citeshttps://doi.org/10.3389/fimmu.2018.01109openalex-snapshot

Immobilized Osteopontin Enhances Adhesion but Suppresses Cytokine Release of Anti-IgE Activated Human Mast Cells

inferred← citeshttps://doi.org/10.3389/fimmu.2018.01392openalex-snapshot

Molecular Regulation of Histamine Synthesis

inferred← citeshttps://doi.org/10.3389/fimmu.2018.01526openalex-snapshot

The Circadian Clock Drives Mast Cell Functions in Allergic Reactions

inferred← citeshttps://doi.org/10.3389/fimmu.2018.03027openalex-snapshot

Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions

inferred← citeshttps://doi.org/10.3389/fimmu.2019.02470openalex-snapshot

Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease

inferred← citeshttps://doi.org/10.3389/fimmu.2020.01389openalex-snapshot

IL33 and Mast Cells—The Key Regulators of Immune Responses in Gastrointestinal Cancers?

inferred← citeshttps://doi.org/10.3389/fimmu.2021.664576openalex-snapshot

In Patients With Obesity, the Number of Adipose Tissue Mast Cells Is Significantly Lower in Subjects With Type 2 Diabetes

inferred← citeshttps://doi.org/10.3389/fimmu.2022.879754openalex-snapshot

The Role of Crosstalk of Immune Cells in Pathogenesis of Chronic Spontaneous Urticaria

inferred← citeshttps://doi.org/10.3389/fimmu.2022.892631openalex-snapshot

On the role of allergen-specific IgG subclasses for blocking human basophil activation

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1171380openalex-snapshot

ELK4 exerts opposite roles in cytokine/chemokine production and degranulation in activated mast cells

inferred← citeshttps://doi.org/10.3390/biom16040539openalex-snapshot

Mast Cells and Substance P: Neuroinflammatory Loops at the Molecular and Translational Clinical Levels

inferred← citeshttps://doi.org/10.3390/biomedicines11030929openalex-snapshot

Mechanisms of COVID-19 Associated Pulmonary Thrombosis: A Narrative Review

inferred← citeshttps://doi.org/10.3390/cancers11030404openalex-snapshot

Allergic Signs in Glioma Pathology: Current Knowledge and Future Perspectives

inferred← citeshttps://doi.org/10.3390/cancers12082203openalex-snapshot

Targeting NF-κB Signaling for Multiple Myeloma

inferred← citeshttps://doi.org/10.3390/cells10081875openalex-snapshot

Mast Cells and the Pancreas in Human Type 1 and Type 2 Diabetes

inferred← citeshttps://doi.org/10.3390/cells8050437openalex-snapshot

The Role of Mast Cells in Stroke

inferred← citeshttps://doi.org/10.3390/ijerph18062889openalex-snapshot

Association of Allergic Diseases and Related Conditions with Dietary Fiber Intake in Korean Adults

inferred← citeshttps://doi.org/10.3390/ijms20082040openalex-snapshot

Mast Cells in Early Rheumatoid Arthritis

inferred← citeshttps://doi.org/10.3390/ijms20184603openalex-snapshot

Mouse Tryptase Gene Expression is Coordinately Regulated by GATA1 and GATA2 in Bone Marrow-Derived Mast Cells

inferred← citeshttps://doi.org/10.3390/ijms21113835openalex-snapshot

Phenotypic and Functional Diversity of Mast Cells

inferred← citeshttps://doi.org/10.3390/ijms21145164openalex-snapshot

Small Molecule NF-κB Pathway Inhibitors in Clinic

inferred← citeshttps://doi.org/10.3390/ijms21155464openalex-snapshot

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes

inferred← citeshttps://doi.org/10.3390/ijms22094935openalex-snapshot

Anaphylaxis: Focus on Transcription Factor Activity

inferred← citeshttps://doi.org/10.3390/jcdd11020054openalex-snapshot

Mast Cells in Cardiac Remodeling: Focus on the Right Ventricle

inferred← citeshttps://doi.org/10.3390/jmse13040811openalex-snapshot

Possible Evolutionary Precursors of Mast Cells: The ‘Granular Cell’ Immunocyte of Botrylloides leachii (Tunicata; Ascidiacea)

inferred← citeshttps://doi.org/10.4103/1673-5374.282238openalex-snapshot

Should mast cells be considered therapeutic targets in multiple sclerosis?

inferred← citeshttps://doi.org/10.55095/achot2018/060openalex-snapshot

Immunohistochemical Detection of Mast and Dendritic Cells in Periprosthetic Tissues of Aseptically Loosened Total Prostheses

inferred← citeshttps://doi.org/10.70675/828c9877z8b20z487ezacb6z3ea67e4f5d73openalex-snapshot

Mast cells, basophils and substance P in sickle cell disease

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