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Health Care–AssociatedClostridium difficileInfection in Canada: Patient Age and Infecting Strain Type Are Highly Predictive of Severe Outcome and Mortality
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.cgh.2009.05.018openalex-snapshot
Clostridium difficile Strain NAP-1 Is Not Associated With Severe Disease in a Nonepidemic Setting
inferredcites →https://doi.org/10.1016/s0140-6736(05)67420-xopenalex-snapshot
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
inferredcites →https://doi.org/10.1056/nejmoa051590openalex-snapshot
An Epidemic, Toxin Gene–Variant Strain of Clostridium difficile
inferredcites →https://doi.org/10.1056/nejmoa051639openalex-snapshot
A Predominantly Clonal Multi-Institutional Outbreak ofClostridium difficile–Associated Diarrhea with High Morbidity and Mortality
inferredcites →https://doi.org/10.1086/502539openalex-snapshot
A Large Outbreak ofClostridium difficile–Associated Disease with an Unexpected Proportion of Deaths and Colectomies at a Teaching Hospital Following Increased Fluoroquinolone Use
inferredcites →https://doi.org/10.1086/510391openalex-snapshot
A Portrait of the Geographic Dissemination of the Clostridium difficile North American Pulsed-Field Type 1 Strain and the Epidemiology of C. difficile-Associated Disease in Quebec
inferredcites →https://doi.org/10.1086/511798openalex-snapshot
Recommendations for Surveillance of Clostridium difficile–Associated Disease
inferredcites →https://doi.org/10.1086/520984openalex-snapshot
Spread and Epidemiology of Clostridium difficile Polymerase Chain Reaction Ribotype 027/Toxinotype III in The Netherlands
inferredcites →https://doi.org/10.1086/596703openalex-snapshot
Health Care–AssociatedClostridium difficileInfection in Adults Admitted to Acute Care Hospitals in Canada: A Canadian Nosocomial Infection Surveillance Program Study
inferredcites →https://doi.org/10.1099/jmm.0.45682-0openalex-snapshot
Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periods
inferredcites →https://doi.org/10.1111/j.1469-0691.2006.01580.xopenalex-snapshot
Emergence of Clostridium difficile-associated disease in North America and Europe
inferredcites →https://doi.org/10.1111/j.1469-0691.2007.01824.xopenalex-snapshot
Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates
inferredcites →https://doi.org/10.1128/aac.00146-08openalex-snapshot
Clostridium difficileInfections in a Canadian Tertiary Care Hospital before and during a Regional Epidemic Associated with the BI/NAP1/027 Strain
inferredcites →https://doi.org/10.1128/aac.00479-06openalex-snapshot
In Vitro Susceptibility of Clostridium difficile Clinical Isolates from a Multi-Institutional Outbreak in Southern Quebec, Canada
inferredcites →https://doi.org/10.1128/jcm.01305-07openalex-snapshot
Yield of Stool Culture with Isolate Toxin Testing versus a Two-Step Algorithm Including Stool Toxin Testing for Detection of Toxigenic Clostridium difficile
inferredcites →https://doi.org/10.1128/jcm.01484-07openalex-snapshot
Comparison of Seven Techniques for Typing International Epidemic Strains of Clostridium difficile : Restriction Endonuclease Analysis, Pulsed-Field Gel Electrophoresis, PCR-Ribotyping, Multilocus Sequence Typing, Multilocus Variable-Number Tandem-Repeat Analysis, Amplified Fragment Length…
inferredcites →https://doi.org/10.1128/jcm.01764-07openalex-snapshot
Use of Highly Discriminatory Fingerprinting to Analyze Clusters of Clostridium difficile Infection Cases Due to Epidemic Ribotype 027 Strains
inferredcites →https://doi.org/10.1128/jcm.02563-05openalex-snapshot
Molecular Analysis of Clostridium difficile PCR Ribotype 027 Isolates from Eastern and Western Canada
inferredcites →https://doi.org/10.1128/jcm.27.10.2386-2387.1989openalex-snapshot
Detection of asymptomatic Clostridium difficile carriage by an alcohol shock procedure
inferredcites →https://doi.org/10.1128/jcm.42.12.5710-5714.2004openalex-snapshot
Multiplex PCR Targetingtpi(Triose Phosphate Isomerase),tcdA(Toxin A), andtcdB(Toxin B) Genes for Toxigenic Culture ofClostridium difficile
inferredcites →https://doi.org/10.1128/jcm.42.9.4316-4318.2004openalex-snapshot
Community-Acquired Clostridium difficile Diarrhea Caused by Binary Toxin, Toxin A, and Toxin B Gene-Positive Isolates in Hungary
inferredcites →https://doi.org/10.1371/journal.pone.0001812openalex-snapshot
Clinical Severity of Clostridium difficile PCR Ribotype 027: A Case-Case Study
inferredcites →https://doi.org/10.1503/cmaj.1041104openalex-snapshot
Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity
inferredcites →https://doi.org/10.2807/ese.13.31.18942-enopenalex-snapshot
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008
inferredcites →https://doi.org/10.3201/eid1203.051064openalex-snapshot
Clostridium difficileInfection in Patients Discharged from US Short-stay Hospitals, 1996–20031
inferredcites →https://doi.org/10.3201/eid1407.070867openalex-snapshot
Attributable Outcomes of EndemicClostridium difficile–associated Disease in Nonsurgical Patients
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Comment traiter une infection digestive à Clostridium difficile en 2014 ?
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Issues Surrounding Antibiotic Use in Older Adults
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Editorial: How Much Do PPIs Contribute to C. difficile Infections?
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Was gibt es Neues in den neuen Leitlinien zur Clostridium difficile-Infektion?
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Clostridium difficile Outbreak Strain BI Is Highly Endemic in Chicago Area Hospitals
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Frequent Hospital Readmissions for Clostridium difficile Infection and the Impact on Estimates of Hospital-Associated C. difficile Burden
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A Multicenter Study ofClostridium difficileInfection—Related Colectomy, 2000—2006
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Clostridium difficileInfection and Limitations of Markers for Severity in Patients with Hematologic Malignancy
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Attributable Burden of Hospital-OnsetClostridium difficileInfection: A Propensity Score Matching Study
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Strategies to Prevent Clostridium difficile Infections in Acute Care Hospitals: 2014 Update
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Efficacy of Bezlotoxumab in Trial Participants Infected With Clostridioides difficile Strain BI Associated With Poor Outcomes
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Type-Specific Risk Factors and Outcome in an Outbreak With 2 Different Clostridium difficile Types Simultaneously in 1 Hospital
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Risk Factors for Mortality in Patients With Clostridium difficile Infection
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Virulence and Clinical Outcomes in Clostridium difficile Infection: A Complex Business
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Renal Failure and Leukocytosis Are Predictors of a Complicated Course of Clostridium difficile Infection if Measured on Day of Diagnosis
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Decreased Cure and Increased Recurrence Rates for Clostridium difficile Infection Caused by the Epidemic C. difficile BI Strain
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Fidaxomicin Versus Vancomycin for Clostridium difficile Infection: Meta-analysis of Pivotal Randomized Controlled Trials
inferred← citeshttps://doi.org/10.1093/cid/cis614openalex-snapshot
Changing Epidemiology of Clostridium difficile Infection Following the Introduction of a National Ribotyping-Based Surveillance Scheme in England
inferred← citeshttps://doi.org/10.1093/cid/cis790openalex-snapshot
Editorial Commentary: 027, 078, and Others: Going Beyond the Numbers (and Away From the Hypervirulence)
inferred← citeshttps://doi.org/10.1093/cid/cit127openalex-snapshot
Relationship Between Bacterial Strain Type, Host Biomarkers, and Mortality in Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1093/cid/cit133openalex-snapshot
Editorial Commentary: Does Infection With Specific Clostridium difficile Strains or Clades Influence Clinical Outcome?
inferred← citeshttps://doi.org/10.1093/cid/cit147openalex-snapshot
Markers of Intestinal Inflammation, Not Bacterial Burden, Correlate With Clinical Outcomes in Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1093/cid/cit346openalex-snapshot
Is Fidaxomicin Worth the Cost? An Economic Analysis
inferred← citeshttps://doi.org/10.1093/cid/cit774openalex-snapshot
Is Fidaxomicin Worth the Cost? The Verdict Is Still Out!
inferred← citeshttps://doi.org/10.1093/cid/ciu125openalex-snapshot
NAP1 Strain Type Predicts Outcomes From Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1093/cid/ciu141openalex-snapshot
Editorial Commentary: Host-Pathogen Interactions in Clostridium difficile Infection: It Takes Two to Tango
inferred← citeshttps://doi.org/10.1093/cid/ciu203openalex-snapshot
Emergence of a Ribotype 244 Strain of Clostridium difficile Associated With Severe Disease and Related to the Epidemic Ribotype 027 Strain
inferred← citeshttps://doi.org/10.1093/cid/ciu316openalex-snapshot
Editorial Commentary: The Trials and Tribulations of Treating Clostridium difficile Infection--One Step Backward, One Step Forward, but Still Progress
inferred← citeshttps://doi.org/10.1093/cid/ciy252openalex-snapshot
Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread
inferred← citeshttps://doi.org/10.1093/gbe/evt204openalex-snapshot
Evolutionary History of the Clostridium difficile Pathogenicity Locus
inferred← citeshttps://doi.org/10.1093/gerona/glv229openalex-snapshot
Older Is Not Wiser, Immunologically Speaking: Effect of Aging on Host Response toClostridium difficileInfections
inferred← citeshttps://doi.org/10.1093/jac/dkaa118openalex-snapshot
Antimicrobial susceptibility of Clostridioides difficile isolated from diarrhoeal stool specimens of Canadian patients: summary of results from the Canadian Clostridioides difficile (CAN-DIFF) surveillance study from 2013 to 2017
inferred← citeshttps://doi.org/10.1093/jac/dks203openalex-snapshot
Policy development for Clostridium difficile
inferred← citeshttps://doi.org/10.1093/jpids/piv011openalex-snapshot
Healthcare-Associated Clostridium difficile Infections and Strain Diversity in Pediatric Hospitals in the Canadian Nosocomial Infection Surveillance Program, 2007-2011
inferred← citeshttps://doi.org/10.1093/ofid/ofv113openalex-snapshot
Association Between Outpatient Antibiotic Prescribing Practices and Community-Associated Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1093/ofid/ofx148openalex-snapshot
Cost-Effectiveness Analysis of Probiotic Use to Prevent Clostridium difficile Infection in Hospitalized Adults Receiving Antibiotics
inferred← citeshttps://doi.org/10.1093/ofid/ofz523openalex-snapshot
The Clinical Burden of Clostridioides difficile in Ontario, Canada
inferred← citeshttps://doi.org/10.1093/ofid/ofz552openalex-snapshot
Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients With Clostridioides difficile Infection
inferred← citeshttps://doi.org/10.1093/pch/19.1.43openalex-snapshot
Clostridium difficile in paediatric populations
inferred← citeshttps://doi.org/10.1093/pch/19.1.49openalex-snapshot
Le Clostridium difficile dans les populations d’âge pédiatrique
inferred← citeshttps://doi.org/10.1097/inf.0b013e318296b424openalex-snapshot
Clostridium difficile Vertebral Osteomyelitis
inferred← citeshttps://doi.org/10.1097/ipc.0000000000000375openalex-snapshot
Initial Therapy for Mild to Moderate Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1097/maj.0b013e3181e939d8openalex-snapshot
Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1097/mog.0b013e32834bc9a9openalex-snapshot
Clostridium difficile infection
inferred← citeshttps://doi.org/10.1097/mrm.0b013e3283573643openalex-snapshot
Clostridium difficile infections
inferred← citeshttps://doi.org/10.1099/acmi.0.000362openalex-snapshot
Comparison of clinical severity, genotype and toxin gene expression of binary toxin-producing Clostridioides difficile clinical isolates in Japan
inferred← citeshttps://doi.org/10.1099/jmm.0.000149openalex-snapshot
Predominance of PCR-ribotypes, 018 (smz) and 369 (trf) of Clostridium difficile in Japan: a potential relationship with other global circulating strains?
inferred← citeshttps://doi.org/10.1099/jmm.0.001991openalex-snapshot
Management of severe and fulminant Clostridioides difficile infection in adults
inferred← citeshttps://doi.org/10.1099/jmm.0.041053-0openalex-snapshot
Multidrug-resistant North American pulsotype 2 Clostridium difficile was the predominant toxigenic hospital-acquired strain in the province of Manitoba, Canada, in 2006–2007
inferred← citeshttps://doi.org/10.1099/jmm.0.056796-0openalex-snapshot
Systemic antibody responses induced by a two-component Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters
inferred← citeshttps://doi.org/10.1099/jmm.0.057968-0openalex-snapshot
Two cases of fulminant colitis due to binary toxin-positive Clostridium difficile that are not PCR ribotype 027 or type 078
inferred← citeshttps://doi.org/10.1099/jmm.0.066399-0openalex-snapshot
Spread of epidemic Clostridium difficile NAP1/027 in Latin America: case reports in Panama
inferred← citeshttps://doi.org/10.1101/2023.09.21.557191openalex-snapshot
A monoclonal antibody collection for C. difficile typing
inferred← citeshttps://doi.org/10.1111/1469-0691.12391openalex-snapshot
Predicting a complicated course of Clostridium difficile infection at the bedside
inferred← citeshttps://doi.org/10.1111/1469-0691.12418openalex-snapshot
European Society of Clinical Microbiology and Infectious Diseases: Update of the Treatment Guidance Document for Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1111/codi.12134openalex-snapshot
Is colectomy for fulminant Clostridium difficile colitis life saving? A systematic review
inferred← citeshttps://doi.org/10.1111/ggi.12866openalex-snapshot
Risk factors for short‐ and long‐term mortality in very old patients with Clostridium difficile infection: A retrospective study
inferred← citeshttps://doi.org/10.1111/ggi.13186openalex-snapshot
Clostridium difficile infection in hospitalized octogenarian patients
inferred← citeshttps://doi.org/10.1111/j.1469-0691.2010.03384.xopenalex-snapshot
Incidence, case fatality and genotypes causing Clostridium difficile infections, Finland, 2008* *Parts of the results were previously presented at the 19th Annual Scientific Meeting of The Society for Healthcare Epidemiology of America (SHEA) 03/2009, San Diego, CA, USA and the 19th European…
inferred← citeshttps://doi.org/10.1111/j.1472-765x.2010.02933.xopenalex-snapshot
Clostridium difficile in vegetables, Canada
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2010.05863.xopenalex-snapshot
Clostridium difficile: progress and challenges
inferred← citeshttps://doi.org/10.1111/j.1863-2378.2010.01352.xopenalex-snapshot
The Ecology and Pathobiology of Clostridium difficile Infections: An Interdisciplinary Challenge
inferred← citeshttps://doi.org/10.1111/jam.12575openalex-snapshot
Fate ofClostridium difficileduring wastewater treatment and incidence in Southern Ontario watersheds
inferred← citeshttps://doi.org/10.1111/jgs.12090openalex-snapshot
Effect of Age on Treatment Outcomes in C lostridium difficile Infection
inferred← citeshttps://doi.org/10.1111/scd.12130openalex-snapshot
Antibiotic‐associated diarrhea and the older dental patient: how do dentists respond?
inferred← citeshttps://doi.org/10.1111/tid.13459openalex-snapshot
Outcomes of C difficile infection in solid‐organ transplant recipients: The National Inpatient Sample (NIS) 2015‐2016
inferred← citeshttps://doi.org/10.11150/kansenshogakuzasshi.90.31openalex-snapshot
JAID/JSC 感染症治療ガイドライン2015 ―腸管感染症―
inferred← citeshttps://doi.org/10.1128/9781555818814.ch3.8openalex-snapshot
Fecal and Other Gastrointestinal Cultures and Toxin Assays
inferred← citeshttps://doi.org/10.1128/9781555818814.ch3.8.1openalex-snapshot
Fecal and Other Gastrointestinal Cultures and Toxin Assays
inferred← citeshttps://doi.org/10.1128/9781555819040.ch20openalex-snapshot
Selected Topics in Anaerobic Bacteriology
inferred← citeshttps://doi.org/10.1128/9781555819453.ch15openalex-snapshot
Clostridium difficileInfection
inferred← citeshttps://doi.org/10.1128/aac.00191-12openalex-snapshot
Characterizations of Clinical Isolates of Clostridium difficile by Toxin Genotypes and by Susceptibility to 12 Antimicrobial Agents, Including Fidaxomicin (OPT-80) and Rifaximin: a Multicenter Study in Taiwan
inferred← citeshttps://doi.org/10.1128/aac.00642-15openalex-snapshot
Risk Factors for Acquisition and Loss of Clostridium difficile Colonization in Hospitalized Patients
inferred← citeshttps://doi.org/10.1128/aac.01170-20openalex-snapshot
In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile
inferred← citeshttps://doi.org/10.1128/cvi.00763-14openalex-snapshot
A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in the Hamster Model
inferred← citeshttps://doi.org/10.1128/iai.00742-17openalex-snapshot
Clostridium difficile Toxoid Vaccine Candidate Confers Broad Protection against a Range of Prevalent Circulating Strains in a Nonclinical Setting
inferred← citeshttps://doi.org/10.1128/iai.01524-14openalex-snapshot
Epidemic Clostridium difficile Strains Demonstrate Increased Competitive Fitness Compared to Nonepidemic Isolates
inferred← citeshttps://doi.org/10.1128/iai.02955-14openalex-snapshot
New Role for Human α-Defensin 5 in the Fight against Hypervirulent Clostridium difficile Strains
inferred← citeshttps://doi.org/10.1128/jcm.00056-13openalex-snapshot
Clostridium difficile Ribotype Diversity at Six Health Care Institutions in the United States
inferred← citeshttps://doi.org/10.1128/jcm.00196-19openalex-snapshot
To Lump or To Split: Does Strain Lineage for Clostridioides difficile Matter?
inferred← citeshttps://doi.org/10.1128/jcm.02970-12openalex-snapshot
Performance of Clostridium difficile Toxin Enzyme Immunoassay and Nucleic Acid Amplification Tests Stratified by Patient Disease Severity
inferred← citeshttps://doi.org/10.1128/jcm.05053-11openalex-snapshot
Lack of Association between Clinical Outcome of Clostridium difficile Infections, Strain Type, and Virulence-Associated Phenotypes
inferred← citeshttps://doi.org/10.1128/jcm.05711-11openalex-snapshot
Clinical and Laboratory Characteristics of Clostridium difficile Infection in Patients with Discordant Diagnostic Test Results
inferred← citeshttps://doi.org/10.1128/mbio.00338-12openalex-snapshot
Toward an Understanding of Changes in Diversity Associated with Fecal Microbiome Transplantation Based on 16S rRNA Gene Deep Sequencing
inferred← citeshttps://doi.org/10.1128/mbio.02368-14openalex-snapshot
A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity
inferred← citeshttps://doi.org/10.1128/microbiolspec.dmih2-0015-2015openalex-snapshot
Selected Topics in Anaerobic Bacteriology
inferred← citeshttps://doi.org/10.1128/microbiolspec.ei10-0007-2015openalex-snapshot
Clostridium difficile Infection
inferred← citeshttps://doi.org/10.1155/2014/793532openalex-snapshot
Clinical and Economic Consequences of Vancomycin and Fidaxomicin for the Treatment of Clostridium difficile Infection in Canada
inferred← citeshttps://doi.org/10.1155/2015/468987openalex-snapshot
Prevalence of Antimicrobial Use in a Network of Canadian Hospitals in 2002 and 2009
inferred← citeshttps://doi.org/10.1155/2016/8048757openalex-snapshot
Fidaxomicin versus Vancomycin in the Treatment ofClostridium difficileInfection: Canadian Outcomes
inferred← citeshttps://doi.org/10.1155/2016/8207418openalex-snapshot
Characterization ofClostridium difficileStrains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region
inferred← citeshttps://doi.org/10.1177/000313481408000628openalex-snapshot
Patience is a Virtue: An Argument for Delayed Surgical Intervention in Fulminant Clostridium difficile Colitis
inferred← citeshttps://doi.org/10.1177/17571774251366935openalex-snapshot
Reduction of C. difficile- associated disease using a multifaceted approach
inferred← citeshttps://doi.org/10.1185/03007995.2013.803058openalex-snapshot
Clostridium difficileinfection in children: a comprehensive review
inferred← citeshttps://doi.org/10.1186/1471-2334-12-370openalex-snapshot
Clostridium difficile 027 infection in Central Italy
inferred← citeshttps://doi.org/10.1186/1471-2334-13-148openalex-snapshot
Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy
inferred← citeshttps://doi.org/10.1186/1471-2431-14-28openalex-snapshot
Severe clinical outcome is uncommon in Clostridium difficile infection in children: a retrospective cohort study
inferred← citeshttps://doi.org/10.1186/1746-6148-8-38openalex-snapshot
Prevalence and molecular characterization of Clostridium difficileisolated from feedlot beef cattle upon arrival and mid-feeding period
inferred← citeshttps://doi.org/10.1186/1756-0500-5-609openalex-snapshot
Clostridium difficile 027-associated pseudomembranous colitis after short-term treatment with cefuroxime and cephalexin in an elderly orthopedic patient: a case report
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