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Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers
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Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group
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Contrasting Patterns of Regulation of the Antioxidant Selenoproteins, Thioredoxin Reductase, and Glutathione Peroxidase, in Cancer Cells
inferredcites →https://doi.org/10.1007/0-387-33827-6_14openalex-snapshot
Regulation of glutathione peroxidase-1 expression
inferredcites →https://doi.org/10.1007/0-387-33827-6_29openalex-snapshot
Mouse models for assessing the role of selenoproteins in health and development
inferredcites →https://doi.org/10.1007/bf02778198openalex-snapshot
The decrement of carcinogenesis by dietary selenium and expression of placental form of glutathione-S-transferase in rat glioma
inferredcites →https://doi.org/10.1007/s00125-008-1055-3openalex-snapshot
Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice
inferredcites →https://doi.org/10.1016/0304-4165(88)90123-7openalex-snapshot
Evidence for specific selenium target tissues and new biologically important selenoproteins
inferredcites →https://doi.org/10.1016/j.cell.2007.06.044openalex-snapshot
Human αB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice
inferredcites →https://doi.org/10.1016/j.cell.2008.10.011openalex-snapshot
Real-Time Redox Measurements during Endoplasmic Reticulum Stress Reveal Interlinked Protein Folding Functions
inferredcites →https://doi.org/10.1016/j.cmet.2009.08.009openalex-snapshot
Reactive Oxygen Species Enhance Insulin Sensitivity
inferredcites →https://doi.org/10.1016/j.cmet.2010.09.015openalex-snapshot
A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance
inferredcites →https://doi.org/10.1023/a:1021263027659openalex-snapshot
New Concepts in Selenium Chemoprevention
inferredcites →https://doi.org/10.1038/ng1655openalex-snapshot
Genetic variation in selenoprotein S influences inflammatory response
inferredcites →https://doi.org/10.1038/sj.onc.1208940openalex-snapshot
Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice
inferredcites →https://doi.org/10.1046/j.1464-410x.2003.04167.xopenalex-snapshot
Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial
inferredcites →https://doi.org/10.1073/pnas.0308096101openalex-snapshot
Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase
inferredcites →https://doi.org/10.1073/pnas.0508218103openalex-snapshot
Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model
inferredcites →https://doi.org/10.1073/pnas.0702027104openalex-snapshot
Regulation of the protein disulfide proteome by mitochondria in mammalian cells
inferredcites →https://doi.org/10.1074/jbc.m900392200openalex-snapshot
Glutathione Peroxidase-1 Regulates Mitochondrial Function to Modulate Redox-dependent Cellular Responses
inferredcites →https://doi.org/10.1079/bjn20031015openalex-snapshot
Selenium and its relationship to cancer: an update
inferredcites →https://doi.org/10.1080/15216540601126694openalex-snapshot
The Sep15 protein family: Roles in disulfide bond formation and quality control in the endoplasmic reticulum
inferredcites →https://doi.org/10.1083/jcb.200911086openalex-snapshot
ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis
inferredcites →https://doi.org/10.1089/ars.2009.2865openalex-snapshot
Structure–Function Relations, Physiological Roles, and Evolution of Mammalian ER-Resident Selenoproteins
inferredcites →https://doi.org/10.1091/mbc.e03-08-0629openalex-snapshot
Methionine Sulfoxide Reduction in Mammals: Characterization of Methionine- R -Sulfoxide Reductases
inferredcites →https://doi.org/10.1093/ajcn/85.5.1439aopenalex-snapshot
Present Knowledge in Nutrition
inferredcites →https://doi.org/10.1093/carcin/20.9.1657openalex-snapshot
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase
inferredcites →https://doi.org/10.1093/emboj/19.24.6882openalex-snapshot
SECIS–SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy
inferredcites →https://doi.org/10.1093/jn/127.5.675openalex-snapshot
Overexpression of Cellular Glutathione Peroxidase Does Not Affect Expression of Plasma Glutathione Peroxidase or Phospholipid Hydroperoxide Glutathione Peroxidase in Mice Offered Diets Adequate or Deficient in Selenium
inferredcites →https://doi.org/10.1093/jn/136.5.1311openalex-snapshot
Both Selenoproteins and Low Molecular Weight Selenocompounds Reduce Colon Cancer Risk in Mice with Genetically Impaired Selenoprotein Expression
inferredcites →https://doi.org/10.1093/jnci/85.18.1483openalex-snapshot
Nutrition Intervention Trials in Linxian, China: Supplementation With Specific Vitamin/Mineral Combinations, Cancer Incidence, and Disease-Specific Mortality in the General Population
inferredcites →https://doi.org/10.1126/science.1083516openalex-snapshot
Characterization of Mammalian Selenoproteomes
inferredcites →https://doi.org/10.1128/mcb.21.11.3840-3852.2001openalex-snapshot
Selective Inhibition of Selenocysteine tRNA Maturation and Selenoprotein Synthesis in Transgenic Mice Expressing Isopentenyladenosine-Deficient Selenocysteine tRNA
inferredcites →https://doi.org/10.1172/jci0214550openalex-snapshot
Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes
inferredcites →https://doi.org/10.1172/jci14550openalex-snapshot
Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes
inferredcites →https://doi.org/10.1201/9781482273106openalex-snapshot
Handbook of Nutritionally Essential Mineral Elements
inferredcites →https://doi.org/10.1210/er.2007-0039openalex-snapshot
The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes
inferredcites →https://doi.org/10.2337/diabetes.51.6.1859openalex-snapshot
Tanis: A Link Between Type 2 Diabetes and Inflammation?
inferredcites →https://doi.org/10.7326/0003-4819-147-4-200708210-00175openalex-snapshot
Effects of Long-Term Selenium Supplementation on the Incidence of Type 2 Diabetes
inferredcites →https://doi.org/10.7326/0003-4819-147-4-200708210-00177openalex-snapshot
Selenium and Diabetes: More Bad News for Supplements
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4049557openalex-extracted
Higher Selenium Was Associated with Higher Risk of Diabetes: Consistent Evidence from Longitudinal and Cross-Sectional Studies Based on Nail and Serum Selenium Measures
inferred← citeshttps://doi.org/10.1002/14651858.cd009671.pub2openalex-snapshot
Selenium supplementation for the primary prevention of cardiovascular disease
inferred← citeshttps://doi.org/10.1002/9781118148143.ch14openalex-snapshot
Selenoproteins in Cellular Redox Regulation and Signaling
inferred← citeshttps://doi.org/10.1002/iub.1466openalex-snapshot
Biological activity of selenium: Revisited
inferred← citeshttps://doi.org/10.1002/jcp.27206openalex-snapshot
miR‐200a‐5p augments cardiomyocyte hypertrophy induced by glucose metabolism disorder via the regulation of selenoproteins
inferred← citeshttps://doi.org/10.1002/jcp.28298openalex-snapshot
Oxidative stress, inflammation, and glycometabolism disorder‐induced erythrocyte hemolysis in selenium‐deficient exudative diathesis broilers
inferred← citeshttps://doi.org/10.1002/jcp.30175openalex-snapshot
Endoplasmic reticulum stress and oxidative stress drive endothelial dysfunction induced by high selenium
inferred← citeshttps://doi.org/10.1002/mnfr.201100766openalex-snapshot
Impact of dietary selenium intake on cardiac health: Experimental approaches and human studies
inferred← citeshttps://doi.org/10.1002/mnfr.201200386openalex-snapshot
Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox‐methylation balance
inferred← citeshttps://doi.org/10.1002/tcr.202500128openalex-snapshot
Crosstalk between Nitric Oxide and Bioinorganic Centers: Implications for Cellular Signaling
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_23openalex-snapshot
Selenoprotein T: From Discovery to Functional Studies Using Conditional Knockout Mice
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_32openalex-snapshot
Sex-Specific Differences in Biological Effects and Metabolism of Selenium
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_44openalex-snapshot
Mutations in Humans That Adversely Affect the Selenoprotein Synthesis Pathway
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_46openalex-snapshot
Selenocysteine tRNA[Ser]Sec Mouse Models for Elucidating Roles of Selenoproteins in Health and Development
inferred← citeshttps://doi.org/10.1007/978-3-319-41283-2_49openalex-snapshot
Glutathione Peroxidase 1: Models for Diabetes and Obesity
inferred← citeshttps://doi.org/10.1007/s00109-012-0896-xopenalex-snapshot
Selenoprotein N in skeletal muscle: from diseases to function
inferred← citeshttps://doi.org/10.1007/s00204-021-03003-5openalex-snapshot
Toxicology and pharmacology of synthetic organoselenium compounds: an update
inferred← citeshttps://doi.org/10.1007/s00394-018-1861-4openalex-snapshot
Maternal selenium status is profoundly involved in metabolic fetal programming by modulating insulin resistance, oxidative balance and energy homeostasis
inferred← citeshttps://doi.org/10.1007/s00420-013-0895-4openalex-snapshot
Features of selenium metabolism in humans living under the conditions of North European Russia
inferred← citeshttps://doi.org/10.1007/s00775-020-01821-zopenalex-snapshot
Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice
inferred← citeshttps://doi.org/10.1007/s10528-012-9532-2openalex-snapshot
Effects of Selenium and Exendin-4 on Glucagon-Like Peptide-1 Receptor, IRS-1, and Raf-1 in the Liver of Diabetic Rats
inferred← citeshttps://doi.org/10.1007/s10534-014-9774-zopenalex-snapshot
Metabolic changes associated with selenium deficiency in mice
inferred← citeshttps://doi.org/10.1007/s10654-018-0422-8openalex-snapshot
Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1007/s11695-015-1808-2openalex-snapshot
Longitudinal Changes in Serum Levels of Angiopoietin-Like Protein 6 and Selenoprotein P After Gastric Bypass Surgery
inferred← citeshttps://doi.org/10.1007/s12011-015-0592-0openalex-snapshot
Effect of Inorganic Dietary Selenium Supplementation on Selenoprotein and Lipid Metabolism Gene Expression Patterns in Liver and Loin Muscle of Growing Lambs
inferred← citeshttps://doi.org/10.1007/s12011-017-1013-3openalex-snapshot
Effects of Selenium Supplementation on the Diabetic Condition Depend on the Baseline Selenium Status in KKAy Mice
inferred← citeshttps://doi.org/10.1007/s12011-019-01721-7openalex-snapshot
Serum Selenium and Lead Levels: a Possible Link with Diabetes and Associated Proteinuria
inferred← citeshttps://doi.org/10.1007/s12011-019-1645-6openalex-snapshot
Selenium Levels in Community Dwellers with Type 2 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/s12011-019-1655-4openalex-snapshot
Effects of Vitamin E and Selenium on Growth Performance, Antioxidant Capacity, and Metabolic Parameters in Growing Furring Blue Foxes (Alopex lagopus)
inferred← citeshttps://doi.org/10.1007/s12011-020-02140-9openalex-snapshot
Selenium Deficiency-Induced Pancreatic Pathology Is Associated with Oxidative Stress and Energy Metabolism Disequilibrium
inferred← citeshttps://doi.org/10.1007/s12011-024-04079-7openalex-snapshot
Increased Expression of PHGDH Under High-Selenium Stress In Vivo
inferred← citeshttps://doi.org/10.1007/s12011-024-04311-4openalex-snapshot
Changes in Cerebrospinal Fluid Concentrations of Selenium Species Induced by Tofersen Administration in Subjects with Amyotrophic Lateral Sclerosis Carrying SOD1 Gene Mutations
inferred← citeshttps://doi.org/10.1007/s12011-024-04492-yopenalex-snapshot
Activation of the De Novo Serine Synthesis Pathway and Disruption of Insulin Signaling Induced by Supplemental SeMet in Vitro
inferred← citeshttps://doi.org/10.1007/s12011-025-04894-6openalex-snapshot
Serine Supplementation Attenuates High-Selenium-Induced Insulin Resistance via Feedback Inhibition of PHGDH in Mice
inferred← citeshttps://doi.org/10.1007/s12012-011-9134-yopenalex-snapshot
Dietary Selenium (Se) and Vitamin E (VE) Supplementation Modulated Methylmercury-Mediated Changes in Markers of Cardiovascular Diseases in Rats
inferred← citeshttps://doi.org/10.1007/s12668-025-01830-9openalex-snapshot
Unveiling the Ameliorative Effects of Phyto-selenium Nanoparticles (PSeNPs) on Anti-hyperglycemic Activity and Hyperglycemia Irradiated Complications
inferred← citeshttps://doi.org/10.1007/s13105-021-00797-xopenalex-snapshot
Associations of methyl donor and methylation inhibitor levels during anti-oxidant therapy in heart failure
inferred← citeshttps://doi.org/10.1007/s13410-013-0111-9openalex-snapshot
Evaluation of serum metallothionein-1, selenium, zinc, and copper in Ghanaian type 2 diabetes mellitus patients
inferred← citeshttps://doi.org/10.1007/s40572-018-0213-0openalex-snapshot
Environmental Selenium and Human Health: an Update
inferred← citeshttps://doi.org/10.1016/b978-0-12-805377-5.00017-5openalex-snapshot
Selenium for Prevention and Mitigation of Oxidative Stress-related Diseases in the Gastrointestinal Tract
inferred← citeshttps://doi.org/10.1016/j.abb.2022.109400openalex-snapshot
Selenium status and type 2 diabetes risk
inferred← citeshttps://doi.org/10.1016/j.aquatox.2018.02.022openalex-snapshot
Cardiometabolic response of juvenile rainbow trout exposed to dietary selenomethionine
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2022.194814openalex-snapshot
Selenoprotein F (SELENOF)-mediated AKT1-FOXO3a-PYGL axis contributes to selenium supranutrition-induced glycogenolysis and lipogenesis
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2012.02.018openalex-snapshot
Understanding selenoprotein function and regulation through the use of rodent models
inferred← citeshttps://doi.org/10.1016/j.cbpb.2015.01.005openalex-snapshot
Molecular cloning and sequence analysis of selenoprotein W gene and its mRNA expression patterns in response to metabolic status and cadmium exposure in goldfish, Carassius auratus
inferred← citeshttps://doi.org/10.1016/j.cbpb.2016.09.004openalex-snapshot
Identification of three selenoprotein T paralogs in goldfish (Carassius auratus) and expression analysis in response to environmental stressors
inferred← citeshttps://doi.org/10.1016/j.cellsig.2017.07.012openalex-snapshot
Selenium deficiency-induced thioredoxin suppression and thioredoxin knock down disbalanced insulin responsiveness in chicken cardiomyocytes through PI3K/Akt pathway inhibition
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.117941openalex-snapshot
Associations of multiple plasma metals with the risk of type 2 diabetes in Chinese adults: A cross-sectional study
inferred← citeshttps://doi.org/10.1016/j.envpol.2019.113325openalex-snapshot
Association between exposure to arsenic, nickel, cadmium, selenium, and zinc and fasting blood glucose levels
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.01.017openalex-snapshot
A high-selenium diet induces insulin resistance in gestating rats and their offspring
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2013.04.003openalex-snapshot
Epidemiology of selenium and type 2 diabetes: Can we make sense of it?
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2013.07.012openalex-snapshot
Selenium and diabetes—Evidence from animal studies
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2013.07.016openalex-snapshot
Interference of selenium and selenoproteins with the insulin-regulated carbohydrate and lipid metabolism
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.12.006openalex-snapshot
Responses to reductive stress in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.02.038openalex-snapshot
Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.04.560openalex-snapshot
Evolution, regulation, and function of porcine selenogenome
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.05.075openalex-snapshot
Selenoproteins in colon cancer
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.05.076openalex-snapshot
Selenoprotein T is a key player in ER proteostasis, endocrine homeostasis and neuroprotection
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.05.077openalex-snapshot
Role of glutathione peroxidase 1 in glucose and lipid metabolism-related diseases
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.06.002openalex-snapshot
Selenium at the redox interface of the genome, metabolome and exposome
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.01.024openalex-snapshot
Glutathione peroxidase-1 inhibits transcription of regenerating islet-derived protein-2 in pancreatic islets
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.08.030openalex-snapshot
Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.06.004openalex-snapshot
The role of glutathione peroxidase-1 in health and disease
inferred← citeshttps://doi.org/10.1016/j.jes.2026.105725openalex-snapshot
Phenolic environmental estrogens exposure, urinary metabolites, and gestational diabetes mellitus: A meet-in-metabolite analysis in pregnant women
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2023.132329openalex-snapshot
Urinary essential and toxic metal mixtures, and type 2 diabetes mellitus: Telomere shortening as an intermediary factor?
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2012.04.011openalex-snapshot
Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2016.12.012openalex-snapshot
Supranutritional selenium intake from enriched milk casein impairs hepatic insulin sensitivity via attenuated IRS/PI3K/AKT signaling and decreased PGC-1α expression in male Sprague–Dawley rats
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.07.002openalex-snapshot
Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2025.110205openalex-snapshot
Betaine supplementation attenuates high-Se induced insulin resistance in C57BL/6 mice
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2026.110326openalex-snapshot
Selenium accumulated exposure aggravates the progression of type 2 diabetes mellitus via activating the IRF2/Caspase-4/GSDMD pyroptosis pathway
inferred← citeshttps://doi.org/10.1016/j.jprot.2020.103653openalex-snapshot
Hepatic proteomic analysis of selenoprotein F knockout mice by iTRAQ: An implication for the roles of selenoprotein F in metabolism and diseases
inferred← citeshttps://doi.org/10.1016/j.jtemb.2016.01.002openalex-snapshot
Effects of selenium supplementation on glucose homeostasis and free androgen index in women with polycystic ovary syndrome: A randomized, double blinded, placebo controlled clinical trial
inferred← citeshttps://doi.org/10.1016/j.jtemb.2016.12.017openalex-snapshot
Alterations of serum trace elements in patients with type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.jtemb.2017.09.023openalex-snapshot
High serum selenium levels are associated with impaired fasting glucose and elevated fasting serum glucose in Linyi, China
inferred← citeshttps://doi.org/10.1016/j.jtemb.2021.126873openalex-snapshot
Association of allelic combinations in selenoprotein and redox related genes with markers of lipid metabolism and oxidative stress – multimarkers analysis in a cross-sectional study
inferred← citeshttps://doi.org/10.1016/j.jtemb.2022.127099openalex-snapshot
Relationship between selenium status, selenoproteins and COVID-19 and other inflammatory diseases: A critical review
inferred← citeshttps://doi.org/10.1016/j.jtemb.2024.127410openalex-snapshot
Dosage-effect of selenium supplementation on blood glucose and oxidative stress in type 2 diabetes mellitus and normal mice
inferred← citeshttps://doi.org/10.1016/j.lfs.2019.116689openalex-snapshot
Maternal metabolic syndrome and selenium: Endocrine energy balance during early programming
inferred← citeshttps://doi.org/10.1016/j.metabol.2019.01.017openalex-snapshot
The tRNA-associated dysregulation in diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.neuro.2013.12.012openalex-snapshot
The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.nutres.2021.06.008openalex-snapshot
Dietary copper and selenium are associated with insulin resistance in overweight and obese Malaysian adults
inferred← citeshttps://doi.org/10.1016/j.redox.2021.102048openalex-snapshot
Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102236openalex-snapshot
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102457openalex-snapshot
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction
inferred← citeshttps://doi.org/10.1016/j.taap.2015.10.019openalex-snapshot
Selenite exacerbates hepatic insulin resistance in mouse model of type 2 diabetes through oxidative stress-mediated JNK pathway
inferred← citeshttps://doi.org/10.1016/j.taap.2019.114744openalex-snapshot
High- and low- selenium diets affect endocrine energy balance during early programming
inferred← citeshttps://doi.org/10.1016/j.tem.2024.03.004openalex-snapshot
Selenium, diabetes, and their intricate sex-specific relationship
inferred← citeshttps://doi.org/10.1016/j.tjnut.2024.10.041openalex-snapshot
Possible Metabolic Remodeling based on de novo Biosynthesis of L-serine in Se-Subtoxic or -Deficient Mammals
inferred← citeshttps://doi.org/10.1016/j.tjnut.2025.11.001openalex-snapshot
Body Selenium Status and Diabetes and Complications: The Multiphased Effect of Selenium
inferred← citeshttps://doi.org/10.1016/s0140-6736(11)61452-9openalex-snapshot
Selenium and human health
inferred← citeshttps://doi.org/10.1017/s0007114518001228openalex-snapshot
Invited commentary in response to: selenium supplementation lowers insulin resistance and markers of cardio-metabolic risk in patients with congestive heart failure: a randomised, double-blind, placebo-controlled trial
inferred← citeshttps://doi.org/10.1017/s0007114522003506openalex-snapshot
Effects of selenium supplementation on glycaemic control markers in healthy rodents: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1017/s0007114522004032openalex-snapshot
Dietary selenium supplementation alleviates low salinity stress in the Pacific white shrimp Litopenaeus vannamei: growth, antioxidative capacity and hepatopancreas transcriptomic responses
inferred← citeshttps://doi.org/10.1021/acs.analchem.6b03136openalex-snapshot
Highly Selective Fluorescent Probe for Imaging H2Se in Living Cells and in Vivo Based on the Disulfide Bond
inferred← citeshttps://doi.org/10.1038/ijo.2014.45openalex-snapshot
Levels of circulating selenoprotein P, fibroblast growth factor (FGF) 21 and FGF23 in relation to the metabolic syndrome in young children
inferred← citeshttps://doi.org/10.1038/s41433-020-01208-zopenalex-snapshot
Association between dietary antioxidants and risk for diabetic retinopathy in a Chinese population
inferred← citeshttps://doi.org/10.1038/s41598-020-75595-4openalex-snapshot
Selenocysteine insertion sequence binding protein 2 (Sbp2) in the sex-specific regulation of selenoprotein gene expression in mouse pancreatic islets
inferred← citeshttps://doi.org/10.1039/c5sc03471jopenalex-snapshot
A highly selective near-infrared fluorescent probe for imaging H 2 Se in living cells and in vivo
inferred← citeshttps://doi.org/10.1039/c6fo00595kopenalex-snapshot
Metabolic syndrome and selenium in fetal programming: gender differences
inferred← citeshttps://doi.org/10.1039/c6ra14932dopenalex-snapshot
Supranutritional dietary selenium induced hyperinsulinemia and dyslipidemia via affected expression of selenoprotein genes and insulin signal-related genes in broiler
inferred← citeshttps://doi.org/10.1039/d0fo00264jopenalex-snapshot
Selenoproteins and renal programming in metabolic syndrome-exposed rat offspring
inferred← citeshttps://doi.org/10.1039/d0mt00165aopenalex-snapshot
Se deficiency induces renal pathological changes by regulating selenoprotein expression, disrupting redox balance, and activating inflammation
inferred← citeshttps://doi.org/10.1042/bcj20170920openalex-snapshot
Emerging roles of endoplasmic reticulum-resident selenoproteins in the regulation of cellular stress responses and the implications for metabolic disease
inferred← citeshttps://doi.org/10.1055/a-2815-9058openalex-snapshot
Adipositas und Spurenelemente – Selen als komplementärer Regulator des metabolischen Systems
inferred← citeshttps://doi.org/10.1074/jbc.m113.471235openalex-snapshot
Deletion of Selenoprotein M Leads to Obesity without Cognitive Deficits
inferred← citeshttps://doi.org/10.1080/10590501.2015.1055163openalex-snapshot
Selenium and Human Health: Witnessing a Copernican Revolution?
inferred← citeshttps://doi.org/10.1080/13813455.2020.1839501openalex-snapshot
Interference of altered plasma trace elements profile with hyperhomocysteinemia and oxidative stress damage to insulin secretion dysfunction in Psammomys obesus : focus on the selenium
inferred← citeshttps://doi.org/10.1089/ars.2011.4145openalex-snapshot
The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1089/ars.2013.5361openalex-snapshot
Glutathione Peroxidase Mimic Ebselen Improves Glucose-Stimulated Insulin Secretion in Murine Islets
inferred← citeshttps://doi.org/10.1093/jn/nxab053openalex-snapshot
Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice
inferred← citeshttps://doi.org/10.1093/jn/nxy036openalex-snapshot
Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice
inferred← citeshttps://doi.org/10.1096/fj.11-180885openalex-snapshot
Adaptive dysfunction of selenoproteins from the perspective of the triage theory: why modest selenium deficiency may increase risk of diseases of aging
inferred← citeshttps://doi.org/10.1096/fj.202400575rropenalex-snapshot
Hepatocyte‐specific Selenoi deficiency predisposes mice to hepatic steatosis and obesity
inferred← citeshttps://doi.org/10.1097/maj.0b013e3182638716openalex-snapshot
Selenium and Cardiometabolic Health: Inconclusive Yet Intriguing Evidence
inferred← citeshttps://doi.org/10.1097/md.0000000000030877openalex-snapshot
Plasma and vitreous selenium concentrations in patients with type 2 diabetes and diabetic retinopathy
inferred← citeshttps://doi.org/10.1111/acel.12529openalex-snapshot
Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice
inferred← citeshttps://doi.org/10.1111/dme.12429openalex-snapshot
Serum selenium in relation to measures of glucose metabolism and incidence of Type 2 diabetes in an older Swedish population
inferred← citeshttps://doi.org/10.1136/bmjdrc-2016-000253openalex-snapshot
High serum selenium levels are associated with increased risk for diabetes mellitus independent of central obesity and insulin resistance
inferred← citeshttps://doi.org/10.1152/physrev.00010.2014openalex-snapshot
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
inferred← citeshttps://doi.org/10.1152/physrev.00039.2013openalex-snapshot
Selenoproteins: Molecular Pathways and Physiological Roles
inferred← citeshttps://doi.org/10.1155/2020/8058463openalex-snapshot
The Correlation between Dietary Selenium Intake and Type 2 Diabetes: A Cross‐Sectional Population‐Based Study on North Chinese Adults
inferred← citeshttps://doi.org/10.1155/2021/5527107openalex-snapshot
Effects of Bariatric Surgeries on Fetuin-A, Selenoprotein P, Angiopoietin-Like Protein 6, and Fibroblast Growth Factor 21 Concentration
inferred← citeshttps://doi.org/10.1172/jci.insight.136283openalex-snapshot
GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity
inferred← citeshttps://doi.org/10.1186/s12937-016-0169-6openalex-snapshot
Association between serum selenium level and type 2 diabetes mellitus: a non-linear dose–response meta-analysis of observational studies
inferred← citeshttps://doi.org/10.1201/b18810-7openalex-snapshot
Selenocysteine tRNA[Ser]Sec: The Central Component of Selenoprotein Biosynthesis
inferred← citeshttps://doi.org/10.1210/en.2013-1167openalex-snapshot
The PACAP-Regulated Gene Selenoprotein T Is Abundantly Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Glucose Tolerance
inferred← citeshttps://doi.org/10.1210/jc.2011-0620openalex-snapshot
Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis
inferred← citeshttps://doi.org/10.1248/bpb.b17-00622openalex-snapshot
Role of Supplementary Selenium on the Induction of Insulin Resistance and Oxidative Stress in NSY Mice Fed a High Fat Diet
inferred← citeshttps://doi.org/10.1371/journal.pone.0045269openalex-snapshot
A Randomized Trial of Selenium Supplementation and Risk of Type-2 Diabetes, as Assessed by Plasma Adiponectin
inferred← citeshttps://doi.org/10.1371/journal.pone.0058278openalex-snapshot
High Dietary Magnesium Intake Is Associated with Low Insulin Resistance in the Newfoundland Population
inferred← citeshttps://doi.org/10.1371/journal.pone.0101315openalex-snapshot
Long-Term Supranutritional Supplementation with Selenate Decreases Hyperglycemia and Promotes Fatty Liver Degeneration by Inducing Hyperinsulinemia in Diabetic db/db Mice
inferred← citeshttps://doi.org/10.1371/journal.pone.0174149openalex-snapshot
High dietary selenium intake is associated with less insulin resistance in the Newfoundland population
inferred← citeshttps://doi.org/10.1371/journal.pone.0182079openalex-snapshot
Pancreatic atrophy caused by dietary selenium deficiency induces hypoinsulinemic hyperglycemia via global down-regulation of selenoprotein encoding genes in broilers
inferred← citeshttps://doi.org/10.15416/ijcp.2019.8.4.301openalex-snapshot
Selenium sebagai Suplemen Terapi Kanker: Sebuah Review
inferred← citeshttps://doi.org/10.1590/s2175-97902018000100139openalex-snapshot
The role of selenium in insulin resistance
inferred← citeshttps://doi.org/10.18632/oncotarget.7814openalex-snapshot
Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2024640/v1openalex-snapshot
The abnormal glucose metabolism due to endogenous serine synthesis for selenoprotein expression in vitro under high-Se
inferred← citeshttps://doi.org/10.2147/dmso.s303146openalex-snapshot
The Involvement of Selenium in Type 2 Diabetes Development Related to Obesity and Low Grade Inflammation
inferred← citeshttps://doi.org/10.2174/0115665240268180231113045836openalex-snapshot
The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats
inferred← citeshttps://doi.org/10.2174/092986711797379249openalex-snapshot
Selenium and Clinical Trials: New Therapeutic Evidence for Multiple Diseases
inferred← citeshttps://doi.org/10.2174/0929867325666180201111159openalex-snapshot
The Role of Selenium in Oxidative Stress and in Nonthyroidal Illness Syndrome (NTIS): An Overview
inferred← citeshttps://doi.org/10.29328/journal.afns.1001013openalex-snapshot
Micronutrient deficiency, a novel nutritional risk factor for insulin resistance and Syndrom X
inferred← citeshttps://doi.org/10.3389/fimmu.2022.952852openalex-snapshot
Mechanism of selenomethionine inhibiting of PDCoV replication in LLC-PK1 cells based on STAT3/miR-125b-5p-1/HK2 signaling
inferred← citeshttps://doi.org/10.3389/fnut.2021.667587openalex-snapshot
Juvenile Selenium Deficiency Impairs Cognition, Sensorimotor Gating, and Energy Homeostasis in Mice
inferred← citeshttps://doi.org/10.3389/fnut.2022.1027629openalex-snapshot
Emerging roles of selenium on metabolism and type 2 diabetes
inferred← citeshttps://doi.org/10.3389/fnut.2022.838613openalex-snapshot
Novel Strategies for Assessing Associations Between Selenium Biomarkers and Cardiometabolic Risk Factors: Concentration, Visit-to-Visit Variability, or Individual Mean? Evidence From a Repeated-Measures Study of Older Adults With High Selenium
inferred← citeshttps://doi.org/10.3389/fpubh.2022.1047605openalex-snapshot
A national cross-sectional analysis of selenium intake and risk of osteoarthritis: NHANES 2003–2016
inferred← citeshttps://doi.org/10.3390/antiox10101558openalex-snapshot
Hydroxy Selenomethionine Improves Meat Quality through Optimal Skeletal Metabolism and Functions of Selenoproteins of Pigs under Chronic Heat Stress
inferred← citeshttps://doi.org/10.3390/antiox11050862openalex-snapshot
Obesity Hinders the Protective Effect of Selenite Supplementation on Insulin Signaling
inferred← citeshttps://doi.org/10.3390/antiox12040846openalex-snapshot
SXRF for Studying the Distribution of Trace Metals in the Pancreas and Liver
inferred← citeshttps://doi.org/10.3390/antiox8050145openalex-snapshot
Maternal Selenium and Developmental Programming
inferred← citeshttps://doi.org/10.3390/biology13040253openalex-snapshot
Mesenchymal Stem Cell-Derived Exosomes Loaded with Selenium or Nano Selenium as a Novel Therapeutic Paradigm for Streptozotocin-Induced Type 1 Diabetes in Rats
inferred← citeshttps://doi.org/10.3390/biom10040658openalex-snapshot
Selenium and Selenoproteins in Adipose Tissue Physiology and Obesity
inferred← citeshttps://doi.org/10.3390/biom13030486openalex-snapshot
Distinct Roles of SELENOF in Different Human Cancers
inferred← citeshttps://doi.org/10.3390/ijms22020496openalex-snapshot
tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors
inferred← citeshttps://doi.org/10.3390/ijms23010005openalex-snapshot
Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly
inferred← citeshttps://doi.org/10.3390/ijms23010106openalex-snapshot
Understanding Cellular Redox Homeostasis: A Challenge for Precision Medicine
inferred← citeshttps://doi.org/10.3390/nano13030424openalex-snapshot
Biogenic Selenium Nanoparticles in Biomedical Sciences: Properties, Current Trends, Novel Opportunities and Emerging Challenges in Theranostic Nanomedicine
inferred← citeshttps://doi.org/10.3390/nu11112584openalex-snapshot
Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice
inferred← citeshttps://doi.org/10.3390/nu13082894openalex-snapshot
Dietary Selenium Deficiency Partially Mimics the Metabolic Effects of Arsenic
inferred← citeshttps://doi.org/10.3390/nu13093238openalex-snapshot
Selenium, a Micronutrient That Modulates Cardiovascular Health via Redox Enzymology
inferred← citeshttps://doi.org/10.3390/nu17020311openalex-snapshot
The Inhibitory Effects of NCT503 and Exogenous Serine on High-Selenium Induced Insulin Resistance in Mice
inferred← citeshttps://doi.org/10.3390/nu17111872openalex-snapshot
Diet in Knee Osteoarthritis—Myths and Facts
inferred← citeshttps://doi.org/10.3390/nu5020340openalex-snapshot
Selenistasis: Epistatic Effects of Selenium on Cardiovascular Phenotype
inferred← citeshttps://doi.org/10.3390/nu5041349openalex-snapshot
Selenium Supranutrition: Are the Potential Benefits of Chemoprevention Outweighed by the Promotion of Diabetes and Insulin Resistance?
inferred← citeshttps://doi.org/10.3390/nu8020080openalex-snapshot
Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes Risk
inferred← citeshttps://doi.org/10.3892/mmr.2015.4006openalex-snapshot
Erythropoietin improves glucose metabolism and pancreatic β-cell damage in experimental diabetic rats
inferred← citeshttps://doi.org/10.3945/jn.112.159020openalex-snapshot
Prolonged Dietary Selenium Deficiency or Excess Does Not Globally Affect Selenoprotein Gene Expression and/or Protein Production in Various Tissues of Pigs
inferred← citeshttps://doi.org/10.3945/jn.112.164764openalex-snapshot
Dietary Selenium Deficiency Partially Rescues Type 2 Diabetes–Like Phenotypes of Glutathione Peroxidase-1–Overexpressing Male Mice3
inferred← citeshttps://doi.org/10.3945/jn.114.198010openalex-snapshot
Optimal Serum Selenium Concentrations Are Associated with Lower Depressive Symptoms and Negative Mood among Young Adults
inferred← citeshttps://doi.org/10.3967/bes2016.109openalex-snapshot
Nail Selenium Level and Diabetes in Older People in Rural China.
inferred← citeshttps://doi.org/10.4010/jln.22.173openalex-snapshot
Statins are Contraindicant to Diabetics - Urgent Proposal
inferred← citeshttps://doi.org/10.4172/2161-1017.1000262openalex-snapshot
Serum Levels of Zinc, Magnesium and Selenium among First Trimester Pregnant Saudi Women with Pre-Diabetes and Diabetes
inferred← citeshttps://doi.org/10.5445/ksp/1000036003openalex-snapshot
Nutzen-Risiko-Bewertung von Mineralstoffen und Spurenelementen : Biochemische, physiologische und toxikologische Aspekte
inferred← citeshttps://doi.org/10.70675/c43c3285z362ez4c6bzb3dczb6ef075d32f9openalex-snapshot
Selenoprotein N as a novel regulator of the muscle progenitor’s cell fate decision process : balancing differentiation and self-renewal
inferred← citeshttps://doi.org/10.70675/f17724cbz825ez4a0az9c31z0b10d6d5f706openalex-snapshot
Rôle de la Sélénoprotéine T dans le remodelage cardiaque post-infarctus et le développement de l'insuffisance cardiaque.
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