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Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s10549-017-4518-8openalex-snapshot
Ribociclib plus letrozole versus letrozole alone in patients with de novo HR+, HER2− advanced breast cancer in the randomized MONALEESA-2 trial
inferredcites →https://doi.org/10.1007/s10549-017-4523-yopenalex-snapshot
Ribociclib with letrozole vs letrozole alone in elderly patients with hormone receptor-positive, HER2-negative breast cancer in the randomized MONALEESA-2 trial
inferredcites →https://doi.org/10.1016/j.ejca.2008.10.026openalex-snapshot
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
inferredcites →https://doi.org/10.1016/s1470-2045(15)00613-0openalex-snapshot
Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial
inferredcites →https://doi.org/10.1056/nejmoa1607303openalex-snapshot
Palbociclib and Letrozole in Advanced Breast Cancer
inferredcites →https://doi.org/10.1056/nejmoa1609709openalex-snapshot
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer
inferredcites →https://doi.org/10.1093/annonc/mdw435.03openalex-snapshot
breast cancer, locally advanced and metastatic First-line ribociclib + letrozole for postmenopausal women with hormone receptor-positive (HR+), HER2-negative (HER2–), advanced breast cancer (ABC)
inferredcites →https://doi.org/10.1126/scitranslmed.aac7551openalex-snapshot
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-1029openalex-snapshot
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.
inferredcites →https://doi.org/10.1200/jco.2017.35.15_suppl.1020openalex-snapshot
Health-related quality of life (HRQoL) of postmenopausal women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) treated with ribociclib + letrozole: Results from MONALEESA-2.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Discovery of Kisqali ® (Ribociclib): A CDK 4/6 Inhibitor for the Treatment of HR +/ HER 2− Advanced Breast Cancer
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Treatment patterns and clinical outcomes of chidamide combined with endocrine therapy in hormone receptor‐positive, HER2 ‐negative metastatic breast cancer: A real‐world multicenter study
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Timing and Patterns of Relapse‐Related Events Following Adjuvant CDK4 /6 Inhibitors Combined With Endocrine Therapy in Patients With HR ‐Positive, HER2 ‐Negative Early Breast Cancer
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The impact of new systemic therapies on survival and time on hormonal treatment in hormone receptor–positive, human epidermal growth factor receptor 2–negative metastatic breast cancer: A population‐based study in British Columbia from 2003 to 2013
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Real‐world study of palbociclib combined with endocrine therapy for patients with metastatic breast cancer: A comparison of subsequent treatment patterns and HER2 expression analysis
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Cost‐effectiveness of ribociclib as initial treatment for premenopausal women with advanced breast cancer in Singapore
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Evaluation of Absolute Oral Bioavailability and Bioequivalence of Ribociclib, a Cyclin‐Dependent Kinase 4/6 Inhibitor, in Healthy Subjects
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Alternative Splicing in Cyclin‐Dependent Kinase 4/6 Inhibitor Resistance in Estrogen Receptor‐Positive Breast Cancer
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Dependency of Cholangiocarcinoma on Cyclin D–Dependent Kinase Activity
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Predictive Role of Serum Inflammatory Markers in Metastatic Luminal A/B Breast Cancers Receiving CDK‐4/6 Inhibitors Therapy
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Palbociclib plus endocrine therapy significantly enhances overall survival of HR +/ HER2 − metastatic breast cancer patients compared to endocrine therapy alone in the second‐line setting: A large institutional study
inferred← citeshttps://doi.org/10.1002/ijc.34570openalex-snapshot
The trichotomy of HER2 expression confers new insights into the understanding and managing for breast cancer stratified by HER2 status
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Head‐to‐head comparison of palbociclib and ribociclib in first‐line treatment of HR ‐positive/ HER2 ‐negative metastatic breast cancer with real‐world data from the OPAL registry
inferred← citeshttps://doi.org/10.1002/ijc.70433openalex-snapshot
Prediction of dose reductions and impact of reduced starting doses of CDK4 /6i on effectiveness in HR ‐positive/ HER2 ‐negative metastatic breast cancer: Real‐world data from the OPAL registry
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Pharmacokinetics of Ribociclib in Subjects With Hepatic Impairment
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Quantitative Assessment of Ribociclib Exposure–Response Relationship to Justify Dose Regimen in Patients with Advanced Breast Cancer
inferred← citeshttps://doi.org/10.1002/jms.4984openalex-snapshot
Simple and rapid quantification of ribociclib in rat plasma by protein precipitation and LC‐MS/MS: An application to pharmacokinetics of ribociclib nanoparticles in rats
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Small molecule inhibitors targeting the cancers
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Breast Cancer: Molecular Pathogenesis and Targeted Therapy
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Analyzing the scaffold diversity of cyclin‐dependent kinase inhibitors and revisiting the clinical and preclinical pipeline
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CDK4 /6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy‐induced diarrhea
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Thrombosis Across Female‐Specific Malignancies: From Chemotherapy‐Driven Risk to Prophylaxis and Drug Interactions
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An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
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A Hormone Immunotherapy (HIT) Combination in Advanced Breast Cancer
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Treatment of Metastatic Breast Cancer: Endocrine Therapy
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Systemic Treatment Drugs/Regimens and Dose Modifications
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Neurological Complications of Targeted Therapies
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Management of Advanced Breast Cancer in Young Women: What’s New in Systemic Treatment
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Cardiotoxicity
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New Concepts in Cardio-Oncology
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CDK4/6 Inhibitor Resistance in ER+ Breast Cancer
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Borderline Ovarian Tumours and Low-Grade Serous Carcinoma
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Neurological Complications of Targeted Therapies
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Endocrine Therapy of Metastatic Breast Cancer
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Endokrine Therapie des metastasierten Mammakarzinoms
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Endokrine Kombinationstherapien beim lokal fortgeschrittenen, metastasierten Mammakarzinom – zusammen besser als allein
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Das metastasierte Mammakarzinom – ein Überblick über die Therapiestandards
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R-5780, a SagA-engineered Lactococcus lactis, is a safe oral synthetic-biology microbial therapy that potentiates PD-1 blockade
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Cardiovascular toxicity of breast cancer treatment: an update
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Neuroendocrine neoplasms of the breast: a review of literature
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Characterization of clinicopathological features, treatment practices, and outcomes among Finnish advanced breast cancer patients in real-life clinical practice
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Management of hepatotoxicity associated with CDK4/6 inhibitors and rechallenge strategies in metastatic hormone-positive, HER2-negative breast cancer
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Updated Austrian treatment algorithm for metastatic triple-negative breast cancer
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Was kommt nach CDK4/6-Inhibition? Perspektiven beim fortgeschrittenen Mammakarzinom
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Cardiac safety of ribociclib evaluated with 24-hour rhythm Holter electrocardiogram
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Hepatotoxicity across CDK 4/6 inhibitors: a Narrative Review
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Neue Entwicklungen der Systemtherapie maligner Erkrankungen
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Endokrine Therapie des metastasierten Mammakarzinoms
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Health-related quality of life of postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer treated with ribociclib + letrozole: results from MONALEESA-2
inferred← citeshttps://doi.org/10.1007/s10549-018-4901-0openalex-snapshot
CDK4/6 inhibitors in advanced hormone receptor-positive/HER2-negative breast cancer: a systematic review and meta-analysis of randomized trials
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Real-world clinical outcomes and toxicity in metastatic breast cancer patients treated with palbociclib and endocrine therapy
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Cost-effectiveness analysis of palbociclib or ribociclib in the treatment of advanced hormone receptor-positive, HER2-negative breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-019-05261-5openalex-snapshot
Management of toxicities associated with targeted therapies for HR-positive metastatic breast cancer: a multidisciplinary approach is the key to success
inferred← citeshttps://doi.org/10.1007/s10549-019-05349-yopenalex-snapshot
PIK3CA mutations early persistence in cell-free tumor DNA as a negative prognostic factor in metastatic breast cancer patients treated with hormonal therapy
inferred← citeshttps://doi.org/10.1007/s10549-020-05617-2openalex-snapshot
Computed tomography-based analyses of baseline body composition parameters and changes in breast cancer patients under treatment with CDK 4/6 inhibitors
inferred← citeshttps://doi.org/10.1007/s10549-021-06215-6openalex-snapshot
Dose modifications of ribociclib and endocrine therapy for treatment of ER+ HER2− metastatic breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-021-06334-0openalex-snapshot
Full population results from the core phase of CompLEEment-1, a phase 3b study of ribociclib plus letrozole as first-line therapy for advanced breast cancer in an expanded population
inferred← citeshttps://doi.org/10.1007/s10549-021-06382-6openalex-snapshot
Progression-free survival on endocrine therapy, before or after chemotherapy, in hormone receptor-positive HER2-negative metastatic breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-022-06543-1openalex-snapshot
Ribociclib plus letrozole in male patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: subgroup analysis of the phase IIIb CompLEEment-1 trial
inferred← citeshttps://doi.org/10.1007/s10549-023-06967-3openalex-snapshot
Plasma cell-free tumor DNA, PIK3CA and TP53 mutations predicted inferior endocrine-based treatment outcome in endocrine receptor-positive metastatic breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-023-07073-0openalex-snapshot
A phase Ib/II study of eribulin in combination with cyclophosphamide in patients with advanced breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-023-07145-1openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10549-023-07226-1openalex-snapshot
The association between HER2-low status and survival in patients with metastatic breast cancer treated with Cyclin-dependent kinases 4 and 6 inhibitors: a systematic review and meta-analysis
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The effects of low HER2 expression on survival in patients with metastatic breast cancer treated with CDK 4/6 inhibitors: a multicenter retrospective study
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First- vs second-line CDK 4/6 inhibitor use for patients with hormone receptor positive, human epidermal growth-factor receptor-2 negative, metastatic breast cancer in the real world setting
inferred← citeshttps://doi.org/10.1007/s10549-025-07879-0openalex-snapshot
Prognostic performance of thymidine kinase 1 activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with CDK4/6 and aromatase inhibitors
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Second-line treatment strategy following CDK4/6 inhibitors for HR-positive and HER2-negative metastatic breast cancer patients: a multicentric, retrospective, observational study
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Real-world second- and third-line progression-free survival after progression on first-line CDK4/6 inhibitors in HR+/HER2- metastatic breast cancer by PAM50 intrinsic subtype: the SOLTI-1801 CDK-PREDICT study
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Alpelisib and Fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the German PRAEGNANT trial
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EVERolimus effectiveness after proGREssion on ENdocrine therapy plus CDK4/6 inhibitor for ER-positive/HER2-negative advanced breast cancer: EVERGREEN study
inferred← citeshttps://doi.org/10.1007/s10549-026-08060-xopenalex-snapshot
Real-world estrogen receptor alpha 1 (ESR1) testing patterns and results for ER+/HER2- metastatic breast cancer in the United States, 2018–2024
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Systematic review of the management of brain metastases from hormone receptor positive breast cancer
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Safety and Efficacy of Ribociclib in Combination with Letrozole in Patients with HR+, HER2− Advanced Breast Cancer: Results from the Italian Subpopulation of Phase 3b CompLEEment-1 Study
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PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degraders for Treatment of Estrogen Receptor–Positive Advanced Breast Cancer
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QT Interval Prolongation Associated With Cytotoxic and Targeted Cancer Therapeutics
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Oligometastatic Breast Cancer: Seeking the Cure by Redefining Stage IV Disease?
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Advances in Endocrine Therapy for Hormone Receptor-Positive Advanced Breast Cancer
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SEOM clinical guidelines in advanced and recurrent breast cancer (2018)
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Expert consensus to optimize the treatment of elderly patients with luminal metastatic breast cancer
inferred← citeshttps://doi.org/10.1007/s12094-023-03247-wopenalex-snapshot
Cost-effectiveness of the addition of CDK4/6 inhibitors to standard endocrine therapy in first-line treatment of women with advanced HR+/HER2− breast cancer in Mexico
inferred← citeshttps://doi.org/10.1007/s12094-024-03399-3openalex-snapshot
Elderly patients with hormone receptor-positive HER2-negative metastatic breast cancer treated with CDK4/6 inhibitors in a multicentre cohort
inferred← citeshttps://doi.org/10.1007/s12094-026-04369-7openalex-snapshot
Expert consensus on optimal management of liver-related adverse events during CDK4/6 inhibitor therapy
inferred← citeshttps://doi.org/10.1007/s12254-021-00718-0openalex-snapshot
Post San Antonio update—my top three abstracts!
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Incidence of and risk factors for non-hematologic toxicity with combined radiotherapy and CDK4/6 inhibitors in metastatic breast cancer using dose-volume parameters analysis: a multicenter cohort study
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The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition
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A genome-wide CRISPR/Cas9 knockout screen identifies SEMA3F gene for resistance to cyclin-dependent kinase 4 and 6 inhibitors in breast cancer
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Advances in the intrinsic signaling pathway interactions and clinical translation of HR+/HER2+ breast cancer
inferred← citeshttps://doi.org/10.1007/s12325-020-01552-2openalex-snapshot
Clinical Challenges in the Management of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer: A Literature Review
inferred← citeshttps://doi.org/10.1007/s12609-019-0308-0openalex-snapshot
Role of Liquid Biopsy in Clinical Decision-Making for Breast Cancer
inferred← citeshttps://doi.org/10.1007/s12609-022-00461-3openalex-snapshot
Mechanisms of Resistance to CDK4/6 Inhibitors in Hormone Receptor-Positive (HR +) Breast Cancer: Spotlight on Convergent CDK6 Upregulation and Immune Signaling
inferred← citeshttps://doi.org/10.1007/s12609-025-00606-0openalex-snapshot
Progress in Clinical Trials of CDK4/6 Inhibitors
inferred← citeshttps://doi.org/10.1007/s12672-025-02820-9openalex-snapshot
Drug treatment of breast cancer brain metastases: progress and challenges
inferred← citeshttps://doi.org/10.1007/s15013-019-1638-8openalex-snapshot
Mammakarzinom: neue Daten zu Ribociclib
inferred← citeshttps://doi.org/10.1007/s15015-018-4353-8openalex-snapshot
Mammakarzinom: CDK4/6-Hemmung auch nach zwei Jahren vorteilhaft
inferred← citeshttps://doi.org/10.1007/s40259-019-00382-1openalex-snapshot
Different Cardiotoxicity of Palbociclib and Ribociclib in Breast Cancer: Gene Expression and Pharmacological Data Analyses, Biological Basis, and Therapeutic Implications
inferred← citeshttps://doi.org/10.1007/s40262-020-00930-xopenalex-snapshot
Clinical Pharmacokinetics and Pharmacodynamics of the Cyclin-Dependent Kinase 4 and 6 Inhibitors Palbociclib, Ribociclib, and Abemaciclib
inferred← citeshttps://doi.org/10.1007/s40262-022-01206-2openalex-snapshot
Justifying Ribociclib Dose in Patients with Advanced Breast Cancer with Renal Impairment Based on PK, Safety, and Efficacy Data: An Innovative Approach Integrating Data from a Dedicated Renal Impairment Study and Oncology Clinical Trials
inferred← citeshttps://doi.org/10.1007/s40262-023-01338-zopenalex-snapshot
Use of Pharmacokinetic and Pharmacodynamic Data to Develop the CDK4/6 Inhibitor Ribociclib for Patients with Advanced Breast Cancer
inferred← citeshttps://doi.org/10.1007/s40264-023-01334-zopenalex-snapshot
Disproportionality Analysis of Abemaciclib in the FDA Adverse Event Reporting System: A Real-World Post-Marketing Pharmacovigilance Assessment
inferred← citeshttps://doi.org/10.1007/s40265-020-01394-wopenalex-snapshot
Targeting the PI3K/AKT/mTOR Pathway in Hormone-Positive Breast Cancer
inferred← citeshttps://doi.org/10.1007/s40265-022-01781-5openalex-snapshot
Emerging Targeted Therapies for Early Breast Cancer
inferred← citeshttps://doi.org/10.1007/s40265-024-02144-yopenalex-snapshot
Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2− Early Breast Cancer
inferred← citeshttps://doi.org/10.1007/s40273-023-01245-yopenalex-snapshot
Cost Effectiveness of CDK4/6 Inhibitors in the First-Line Treatment of HR+/HER2− Metastatic Breast Cancer in Postmenopausal Women in the USA
inferred← citeshttps://doi.org/10.1007/s40487-018-0090-6openalex-snapshot
The Roles of Common Variation and Somatic Mutation in Cancer Pharmacogenomics
inferred← citeshttps://doi.org/10.1007/s40801-022-00327-1openalex-snapshot
Real-World Patient Characteristics, Utilization Patterns, and Outcomes of US Patients with HR+, HER2− Metastatic Breast Cancer Treated with Abemaciclib
inferred← citeshttps://doi.org/10.1007/s40801-023-00391-1openalex-snapshot
Real-World Analysis of Clinical and Demographic Characteristics, Treatment Patterns, and Outcomes in Predominantly Older Patients with HR+/HER2− Metastatic Breast Cancer Receiving Abemaciclib in Routine Clinical Practice
inferred← citeshttps://doi.org/10.1007/s41974-022-00226-xopenalex-snapshot
Kongress-Update zum Mammakarzinom
inferred← citeshttps://doi.org/10.1016/b978-0-12-821666-8.00069-4openalex-snapshot
The effects of anticancer therapies on bone metastases in breast cancer
inferred← citeshttps://doi.org/10.1016/b978-0-323-95116-6.00004-9openalex-snapshot
Somatic mutation: Pharmacogenomics in oncology care
inferred← citeshttps://doi.org/10.1016/b978-0-443-13825-6.00375-7openalex-snapshot
Hormonal treatment of breast cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-23932-8.00022-4openalex-snapshot
Palbociclib, ribociclib, and abemaciclib: potent and selective CDK4/6 inhibitors for the treatment of breast cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-30050-9.00053-9openalex-snapshot
Breast cancer
inferred← citeshttps://doi.org/10.1016/j.annonc.2020.12.003openalex-snapshot
SOLAR1s: alpelisib returns to earth?
inferred← citeshttps://doi.org/10.1016/j.annonc.2020.12.013openalex-snapshot
Palbociclib in combination with endocrine therapy versus capecitabine in hormonal receptor-positive, human epidermal growth factor 2-negative, aromatase inhibitor-resistant metastatic breast cancer: a phase III randomised controlled trial—PEARL
inferred← citeshttps://doi.org/10.1016/j.annonc.2021.09.015openalex-snapshot
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
inferred← citeshttps://doi.org/10.1016/j.annonc.2021.10.214openalex-snapshot
Adjuvant abemaciclib for high-risk breast cancer: the story continues
inferred← citeshttps://doi.org/10.1016/j.annonc.2022.05.006openalex-snapshot
Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer
inferred← citeshttps://doi.org/10.1016/j.annonc.2023.08.011openalex-snapshot
Pooled ctDNA analysis of MONALEESA phase III advanced breast cancer trials
inferred← citeshttps://doi.org/10.1016/j.annonc.2023.11.003openalex-snapshot
Is there a role for continuation of CDK4/6 inhibition after progression on a prior CDK4/6 inhibitor in HR+/HER2− metastatic breast cancer?
inferred← citeshttps://doi.org/10.1016/j.annonc.2024.04.013openalex-snapshot
Abemaciclib plus a nonsteroidal aromatase inhibitor as initial therapy for HR+, HER2− advanced breast cancer: final overall survival results of MONARCH 3
inferred← citeshttps://doi.org/10.1016/j.annonc.2025.03.023openalex-snapshot
Real-world effectiveness comparison of first-line palbociclib, ribociclib or abemaciclib plus endocrine therapy in advanced HR-positive/HER2-negative BC patients: results from the multicenter PALMARES-2 study
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.07.050openalex-snapshot
Post CDK4/6 inhibitors: Novel targeted combinations based on SERDs in HR+/HER2– advanced breast cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188830openalex-snapshot
ESR1 activating mutations: From structure to clinical application
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115209openalex-snapshot
Targeted therapy for breast cancer: An overview of drug classes and outcomes
inferred← citeshttps://doi.org/10.1016/j.breast.2018.10.001openalex-snapshot
Targeting CDK4/6 pathways and beyond in breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2018.11.008openalex-snapshot
Why upfront use of CDK inhibitors for the treatment of advanced breast cancer may be wasteful, and how we can increase their value
inferred← citeshttps://doi.org/10.1016/j.breast.2019.05.001openalex-snapshot
Concurrent radiotherapy with palbociclib or ribociclib for metastatic breast cancer patients: Preliminary assessment of toxicity
inferred← citeshttps://doi.org/10.1016/j.breast.2019.10.016openalex-snapshot
Stereotactic ablative body radiotherapy (SABR) for bone only oligometastatic breast cancer: A prospective clinical trial
inferred← citeshttps://doi.org/10.1016/j.breast.2020.09.008openalex-snapshot
Ribociclib plus fulvestrant for advanced breast cancer: Health-related quality-of-life analyses from the MONALEESA-3 study
inferred← citeshttps://doi.org/10.1016/j.breast.2021.02.015openalex-snapshot
First- and second-line treatment strategies for hormone-receptor (HR)-positive HER2-negative metastatic breast cancer: A real-world study
inferred← citeshttps://doi.org/10.1016/j.breast.2021.05.008openalex-snapshot
The role of CDK4/6 inhibitors in early breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2021.07.002openalex-snapshot
Adjuvant CDK4/6 inhibitors combined with endocrine therapy in HR-positive, HER2-negative early breast cancer: A meta-analysis of randomized clinical trials
inferred← citeshttps://doi.org/10.1016/j.breast.2021.10.001openalex-snapshot
Safety of cyclin-dependent kinase4/6 inhibitor combined with palliative radiotherapy in patients with metastatic breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2021.12.008openalex-snapshot
Integrating CDK4/6 inhibitors in the treatment of patients with early breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2022.09.006openalex-snapshot
Safety and efficacy of ribociclib plus letrozole in patients with HR+, HER2– advanced breast cancer: Results from the Spanish sub-population of the phase 3b CompLEEment-1 trial
inferred← citeshttps://doi.org/10.1016/j.breast.2022.09.009openalex-snapshot
Clinical outcomes of cyclin-dependent kinase 4–6 (CDK 4–6) inhibitors in patients with male breast cancer: A multicenter study
inferred← citeshttps://doi.org/10.1016/j.breast.2022.10.005openalex-snapshot
Concomitant administration of proton pump inhibitors does not significantly affect clinical outcomes in metastatic breast cancer patients treated with ribociclib
inferred← citeshttps://doi.org/10.1016/j.breast.2023.01.005openalex-snapshot
How I treat HER2-low advanced breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2024.103859openalex-snapshot
Beyond Hormone Receptors: liquid biopsy tools to unveil new clinical meanings and empower therapeutic decision-making in Luminal-like metastatic breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2024.103863openalex-snapshot
Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i): Mechanisms of resistance and where to find them
inferred← citeshttps://doi.org/10.1016/j.breast.2025.103875openalex-snapshot
Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer
inferred← citeshttps://doi.org/10.1016/j.breast.2025.104448openalex-snapshot
Real-world palbociclib dose modifications and clinical outcomes in patients with HR+/HER2− metastatic breast cancer: A Flatiron Health database analysis
inferred← citeshttps://doi.org/10.1016/j.breast.2025.104485openalex-snapshot
Expert consensus on treating HR+/HER2- metastatic breast cancer based on real-world practice patterns observed in the RETRACT survey of US oncologists
inferred← citeshttps://doi.org/10.1016/j.breast.2025.104527openalex-snapshot
BEBT-209, a primary CDK4 selective inhibitor, for the treatment of HR+/HER2- advanced breast cancer (BECTOP1): a phase 1, multicentre, open-label study
inferred← citeshttps://doi.org/10.1016/j.breast.2025.104568openalex-snapshot
Baseline neutrophil-lymphocyte ratio (NLR) predicts toxicity and survival in HR+/HER-2 breast cancer patients treated with CDK4/6 inhibitors
inferred← citeshttps://doi.org/10.1016/j.breast.2025.104607openalex-snapshot
Improving survival outcomes of people with ABC: a global expert review and call-to-action for 2025–2035 (Goal 1)
inferred← citeshttps://doi.org/10.1016/j.breast.2026.104692openalex-snapshot
Effectiveness comparison of first-line CDK4/6 inhibitors in patients with hormone-positive HER2-negative advanced breast cancer according to tumor histology: a sub-analysis of the real-world, multicenter, Italian study PALMARES-2
inferred← citeshttps://doi.org/10.1016/j.breast.2026.104769openalex-snapshot
Real-world effectiveness of CDK4/6 inhibitors in older patients with HR+/HER2- advanced breast cancer: a sub-analysis of the multicenter, PALMARES-2 study
inferred← citeshttps://doi.org/10.1016/j.breast.2026.104817openalex-snapshot
Interplay between HER2-Low status, hormone receptor expression, and therapeutic response to cyclin-dependent kinase 4/6 inhibitors as first-line treatment in luminal-like metastatic breast cancer: The CYCLHER study
inferred← citeshttps://doi.org/10.1016/j.bulcan.2021.04.007openalex-snapshot
Place des inhibiteurs de kinases dépendantes des cyclines 4/6 dans la prise en charge du cancer du sein avancé
inferred← citeshttps://doi.org/10.1016/j.bulcan.2021.12.009openalex-snapshot
Actualités 2021 sur le cancer du sein localement avancé ou métastatique RH+/HER2−
inferred← citeshttps://doi.org/10.1016/j.bulcan.2023.01.002openalex-snapshot
2022 : nouvelles pratiques thérapeutiques en oncologie mammaire
inferred← citeshttps://doi.org/10.1016/j.canlet.2026.218737openalex-snapshot
Membrane bionic supramolecular nanomaterials for co-delivered of ribociclib and PEG10 siRNA for targeted therapy in breast cancer
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.110278openalex-snapshot
Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112314openalex-snapshot
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
inferred← citeshttps://doi.org/10.1016/j.clbc.2019.02.004openalex-snapshot
Palbociclib or Ribociclib in First-Line Treatment in Patients With Hormone Receptor–Positive/Human Epidermal Receptor 2–Negative Advanced or Metastatic Breast Cancer? A Perspective Based on Pharmacologic Costs
inferred← citeshttps://doi.org/10.1016/j.clbc.2019.06.011openalex-snapshot
First-Line Treatment for Endocrine-Sensitive Bone-Only Metastatic Breast Cancer: Systematic Review and Meta-analysis
inferred← citeshttps://doi.org/10.1016/j.clbc.2019.06.017openalex-snapshot
Practical Treatment Strategies and Future Directions After Progression While Receiving CDK4/6 Inhibition and Endocrine Therapy in Advanced HR+/HER2− Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.clbc.2021.07.013openalex-snapshot
Incidence and Severity of Myelosuppression With Palbociclib After Palliative Bone Radiation in Advanced Breast Cancer: A Single Center Experience and Review of Literature
inferred← citeshttps://doi.org/10.1016/j.clbc.2021.08.002openalex-snapshot
Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?
inferred← citeshttps://doi.org/10.1016/j.clbc.2021.08.007openalex-snapshot
The Effects of HER2 on CDK4/6 Activity in Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.clbc.2021.10.007openalex-snapshot
The Place of Chemotherapy in The Evolving Treatment Landscape for Patients With HR-positive/HER2-negative MBC
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