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Therapeutic advantage of genetically engineered Salmonella typhimurium carrying short hairpin RNA against inhibin alpha subunit in cancer treatment

https://doi.org/10.1093/annonc/mdy240
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.1489openalex-snapshot
Oral cytokine gene therapy against murine tumor using attenuatedSalmonella typhimurium
inferredcites →https://doi.org/10.1007/0-306-46817-4_6openalex-snapshot
Tumor-Targeted Salmonella
inferredcites →https://doi.org/10.1007/978-1-4939-3515-4_8openalex-snapshot
Employment of Salmonella in Cancer Gene Therapy
inferredcites →https://doi.org/10.1016/j.mce.2004.02.015openalex-snapshot
Re-evaluation of inhibin α subunit as a tumour suppressor in prostate cancer
inferredcites →https://doi.org/10.1016/s0034-5288(18)32968-0openalex-snapshot
Experimental Salmonella typhimurium infection in calves
inferredcites →https://doi.org/10.1016/s0168-3659(01)00340-6openalex-snapshot
Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET™) for diagnostic imaging
inferredcites →https://doi.org/10.1038/360313a0openalex-snapshot
α-lnhibin is a tumour-suppressor gene with gonadal specificity in mice
inferredcites →https://doi.org/10.1038/nbt0892-888openalex-snapshot
Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine
inferredcites →https://doi.org/10.1073/pnas.91.19.8817openalex-snapshot
Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice.
inferredcites →https://doi.org/10.1097/01.ju.0000100048.98807.b7openalex-snapshot
Elevated Expression of Inhibin α in Prostate Cancer
inferredcites →https://doi.org/10.1128/jb.156.1.471-474.1983openalex-snapshot
Salmonella typhimurium LT2 strains which are r- m+ for all three chromosomally located systems of DNA restriction and modification

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4064543openalex-extracted
Efficacy of Bivalent CEACAM6/4-1BBL Genetic Vaccine Combined with Anti-PD1 Antibody in MC38 Tumor Model of Mice
inferred← citeshttps://doi.org/10.1002/adhm.202401076openalex-snapshot
Recent Advances in Bacterium‐Based Therapeutic Modalities for Melanoma Treatment
inferred← citeshttps://doi.org/10.1002/adhm.202401538openalex-snapshot
The Rational Engineered Bacteria Based Biohybrid Living System for Tumor Therapy
inferred← citeshttps://doi.org/10.1002/advs.202301835openalex-snapshot
Neutrophil‐Mediated Tumor‐Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy
inferred← citeshttps://doi.org/10.1002/bab.2738openalex-snapshot
Genetically Engineered Bacteria as a Promising Therapeutic Strategy Against Cancer: A Comprehensive Review
inferred← citeshttps://doi.org/10.1002/mco2.71052openalex-snapshot
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
inferred← citeshttps://doi.org/10.1002/smll.202305764openalex-snapshot
Image‐Guided Photothermal and Immune Therapy of Tumors via Melanin‐Producing Genetically Engineered Bacteria
inferred← citeshttps://doi.org/10.1007/978-981-13-8844-6_3openalex-snapshot
Microbial-Based Cancer Therapy: Diagnostic Tools and Therapeutic Strategies
inferred← citeshttps://doi.org/10.1007/s00262-020-02817-zopenalex-snapshot
Immune signature-based risk stratification and prediction of immune checkpoint inhibitor’s efficacy for lung adenocarcinoma
inferred← citeshttps://doi.org/10.1007/s10555-026-10318-1openalex-snapshot
Shaping death: how the microbiome regulates tumour cell demise and therapy response
inferred← citeshttps://doi.org/10.1007/s11095-022-03240-yopenalex-snapshot
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies
inferred← citeshttps://doi.org/10.1007/s11274-025-04716-wopenalex-snapshot
Exploiting Salmonella typhimurium as a novel cancer therapeutic agent: from tumor colonization to metabolic engineering
inferred← citeshttps://doi.org/10.1007/s40588-019-00132-5openalex-snapshot
Salmonella Typhimurium as an Anticancer Therapy: Recent Advances and Perspectives
inferred← citeshttps://doi.org/10.1016/j.addr.2022.114363openalex-snapshot
Bacterially mediated drug delivery and therapeutics: Strategies and advancements
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188846openalex-snapshot
Intratumoral bacteria are an important “accomplice” in tumor development and metastasis
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.09.012openalex-snapshot
Engineered bacteria and bacteria-derived nanomaterials for cancer therapy: Mechanisms, designs and advances
inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101733openalex-snapshot
The specific hallmarks, emerging roles, key mechanisms, and clinical applications of intra-tumoral microbiota in human cancers
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e10775openalex-snapshot
Efficacy of bivalent CEACAM6/4-1BBL genetic vaccine combined with anti-PD1 antibody in MC38 tumor model of mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.106944openalex-snapshot
Therapeutic vaccines for colorectal cancer: The progress and future prospect
inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108366openalex-snapshot
Microbial therapeutic agents as a new frontier in tumor-targeted drug delivery
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.05.003openalex-snapshot
Microbial cancer therapeutics: A promising approach
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.06.011openalex-snapshot
Multidimensional role of bacteria in cancer: Mechanisms insight, diagnostic, preventive and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.tranon.2023.101679openalex-snapshot
INHA acts as a novel and potential biomarker in lung adenocarcinoma and shapes the immune-suppressive tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.trecan.2020.11.004openalex-snapshot
Tweak to Treat: Reprograming Bacteria for Cancer Treatment
inferred← citeshttps://doi.org/10.1038/s41526-023-00285-0openalex-snapshot
Microbial applications for sustainable space exploration beyond low Earth orbit
inferred← citeshttps://doi.org/10.1038/s41598-020-72864-0openalex-snapshot
Transcriptional characterization of conjunctival melanoma identifies the cellular tumor microenvironment and prognostic gene signatures
inferred← citeshttps://doi.org/10.1080/21505594.2026.2696642openalex-snapshot
Colorectal cancer landscape from gut microbiota: Insights into mutations, epigenetic dysregulation, and immune microenvironment alterations
inferred← citeshttps://doi.org/10.1093/g3journal/jkab226openalex-snapshot
Genome archaeology of two laboratory Salmonella enterica enterica sv Typhimurium
inferred← citeshttps://doi.org/10.1097/cm9.0000000000003807openalex-snapshot
Engineered bacteria for cancer therapy: Advancements, challenges, and future directions
inferred← citeshttps://doi.org/10.1097/js9.0000000000002573openalex-snapshot
Colorectal cancer: the immune microenvironment and the gut microbiota – new perspectives, challenges, and opportunities
inferred← citeshttps://doi.org/10.1186/s13568-019-0910-6openalex-snapshot
Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1β in two pathways
inferred← citeshttps://doi.org/10.1186/s43088-024-00471-3openalex-snapshot
The association of p21, inhibin, and Tob-1 expression with the clinicopathological characteristics of benign and malignant colorectal lesions
inferred← citeshttps://doi.org/10.17140/vroj-4-111openalex-snapshot
Salmonella-based Anticancer Vaccines and their Efficacy
inferred← citeshttps://doi.org/10.20517/mrr.2024.57openalex-snapshot
Potential applications of engineered bacteria in disease diagnosis and treatment
inferred← citeshttps://doi.org/10.3389/fcell.2022.790920openalex-snapshot
Development of Tumor Mutation Burden-Related Prognostic Model and Novel Biomarker Identification in Stomach Adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fcimb.2023.1293351openalex-snapshot
Salmonella enterica and outer membrane vesicles are current and future options for cancer treatment
inferred← citeshttps://doi.org/10.3389/fonc.2021.624759openalex-snapshot
Use of Salmonella Bacteria in Cancer Therapy: Direct, Drug Delivery and Combination Approaches
inferred← citeshttps://doi.org/10.3390/cancers11101592openalex-snapshot
Targeting Programmed Fusobacterium nucleatum Fap2 for Colorectal Cancer Therapy
inferred← citeshttps://doi.org/10.3390/ijms25073896openalex-snapshot
A Review of the Use of Native and Engineered Probiotics for Colorectal Cancer Therapy
inferred← citeshttps://doi.org/10.3390/microorganisms12030430openalex-snapshot
Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives
inferred← citeshttps://doi.org/10.3390/microorganisms9112408openalex-snapshot
Combined Therapy with microRNA-Expressing Salmonella and Irradiation in Melanoma
inferred← citeshttps://doi.org/10.3390/vaccines11071275openalex-snapshot
Synergistic Antitumor Effect of Combined Radiotherapy and Engineered Salmonella typhimurium in an Intracranial Sarcoma Mouse Model
inferred← citeshttps://doi.org/10.3390/vaccines13040405openalex-snapshot
Salmonella-Based Vaccine: A Promising Strategy for Type 1 Diabetes
inferred← citeshttps://doi.org/10.3724/abbs.2023007openalex-snapshot
Salmonella typhimurium may support cancer treatment: a review
inferred← citeshttps://doi.org/10.47749/t/unicamp.2022.1373632openalex-snapshot
Salmonella enterica e vesículas de membrana externa como agente antitumoral
inferred← citeshttps://doi.org/10.7150/jca.32650openalex-snapshot
Salmonella -Mediated Cancer Therapy: An Innovative Therapeutic Strategy
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