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ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data

https://doi.org/10.1093/bioinformatics/bti476
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Partial linear fit: A new NMR spectroscopy preprocessing tool for pattern recognition applications
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Articular hypermobility is a protective factor for hand osteoarthritis
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Multivariate response surface modelling by principal components analysis
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Batch statistical processing of 1H NMR‐derived urinary spectral data
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PRINCIPAL RESPONSE CURVES: ANALYSIS OF TIME-DEPENDENT MULTIVARIATE RESPONSES OF BIOLOGICAL COMMUNITY TO STRESS
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Pattern recognition analysis of high resolution 1H NMR spectra of urine. A nonlinear mapping approach to the classification of toxicological data
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Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-arthritic Human Hips. II: Correlation of Morphology with Biochemical and Metabolic Data
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The Role of Metabolomics in Systems Biology
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Metabolomics — the link between genotypes and phenotypes
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Multivariate analysis of variance (MANOVA)
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Multilevel component analysis of time-resolved metabolic fingerprinting data
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Statistical experimental design and partial least squares regression analysis of biofluid metabonomic NMR and clinical chemistry data for screening of adverse drug effects
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Evaluation of field-desorption and fast atom-bombardment mass spectrometric profiles by pattern recognition techniques
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Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling
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Osteoarthritis
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Geometric Trajectory Analysis of Metabolic Responses To Toxicity Can Define Treatment Specific Profiles
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Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis
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Multivariate Analysis of Quality. An Introduction
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Integrative Biological Analysis of the APOE∗3-Leiden Transgenic Mouse
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Quantitative metabolic profiling based on gas chromatography.
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Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.
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Identification of Disease- and Nutrient-Related Metabolic Fingerprints in Osteoarthritic Guinea Pigs
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Animal Models of Osteoarthritis
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The Scree Test For The Number Of Factors
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Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips
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A User's Guide to Principal Components
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Multivariate Analysis of Variance.
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Multivariate Analysis of Variance (MANOVA)
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Some Applications of Multivariate Methods in Botany
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Principal Component Analysis of Designed Experiment

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Multilevel dimensionality-reduction methods
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Computational and statistical analysis of metabolomics data
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Real-time metabolomic analysis of lactic acid bacteria as monitored by in vitro NMR and chemometrics
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Evaluation of metabolomics profiles of grain from maize hybrids derived from near-isogenic GM positive and negative segregant inbreds demonstrates that observed differences cannot be attributed unequivocally to the GM trait
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Metabolomics analysis of oil palm (Elaeis guineensis) leaf: evaluation of sample preparation steps using UHPLC–MS/MS
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Identification of weak and gender specific effects in a short 3 weeks intervention study using barley and oat mixed linkage β-glucan dietary supplements: a human fecal metabolome study by GC-MS
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Group-wise ANOVA simultaneous component analysis for designed omics experiments
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Common and distinct variation in data fusion of designed experimental data
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Longitudinal analysis of the salivary metabolome of breast-fed and formula-fed infants over the first year of life
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The plasma metabolome of Atlantic salmon as studied by 1H NMR spectroscopy using standard operating procedures: effect of aquaculture location and growth stage
inferred← citeshttps://doi.org/10.1007/s11306-023-02005-xopenalex-snapshot
Associations between sheep meat intake frequency and blood plasma levels of metabolites and lipoproteins in healthy Uzbek adults
inferred← citeshttps://doi.org/10.1007/s11306-023-02030-wopenalex-snapshot
Non-target ROIMCR LC–MS analysis of the disruptive effects of TBT over time on the lipidomics of Daphnia magna
inferred← citeshttps://doi.org/10.1007/s11306-024-02128-9openalex-snapshot
Revealing static and dynamic biomarkers from postprandial metabolomics data through coupled matrix and tensor factorizations
inferred← citeshttps://doi.org/10.1007/s11306-025-02329-wopenalex-snapshot
Pre-partum feeding strategies affect colostrum metabolite levels related to nitrogen and energy metabolism in Holstein dairy cows
inferred← citeshttps://doi.org/10.1007/s11356-013-2154-3openalex-snapshot
Assessment of the applicability of a “toolbox” designed for microbially assisted phytoremediation: the case study at Ingurtosu mining site (Italy)
inferred← citeshttps://doi.org/10.1007/s11947-019-02266-2openalex-snapshot
Milk Renneting: Study of Process Factor Influences by FT-NIR Spectroscopy and Chemometrics
inferred← citeshttps://doi.org/10.1007/s11947-023-03266-zopenalex-snapshot
A New Index to Detect Process Deviations Using IR Spectroscopy and Chemometrics Process Tools
inferred← citeshttps://doi.org/10.1007/s12263-008-0084-3openalex-snapshot
The challenges for molecular nutrition research 2: quantification of the nutritional phenotype
inferred← citeshttps://doi.org/10.1007/s40520-016-0708-1openalex-snapshot
Biomarkers for physical frailty and sarcopenia
inferred← citeshttps://doi.org/10.1016/0169-7439(92)80046-7openalex-snapshot
Chemometrics and intelligent laboratory systems
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14577-9openalex-snapshot
Regularized Multivariate Analysis of Variance
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14578-0openalex-snapshot
ANOVA-Target Projection (ANOVA-TP)
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14579-2openalex-snapshot
The Essentials on Linear Regression, ANOVA, General Linear and Linear Mixed Models for the Chemist
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14593-7openalex-snapshot
Analysis of Metabolomics Data—A Chemometrics Perspective
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14602-5openalex-snapshot
Chemometrics Analysis of Big Data
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14882-6openalex-snapshot
Analysis of Megavariate Data in Functional Omics
inferred← citeshttps://doi.org/10.1016/b978-0-12-814872-3.00001-1openalex-snapshot
Introducing Metabolomics
inferred← citeshttps://doi.org/10.1016/b978-0-12-814872-3.00002-3openalex-snapshot
An Integrated Approach to Plant Biology via Multi-Analogous Methods
inferred← citeshttps://doi.org/10.1016/b978-0-12-819590-1.00012-4openalex-snapshot
Metabolomics of medicinal and aromatic plants: Goldmines of secondary metabolites for herbal medicine research
inferred← citeshttps://doi.org/10.1016/b978-0-443-13261-2.00019-9openalex-snapshot
Replicate analysis for uncertainty estimation in PARAFAC and PARAFASCA analyses of factorial metabolomics data
inferred← citeshttps://doi.org/10.1016/b978-0-443-21493-6.00003-4openalex-snapshot
Experimental design for chemometrics: best practices
inferred← citeshttps://doi.org/10.1016/b978-0-443-22163-7.00014-0openalex-snapshot
Variable selection for analytical chemistry data
inferred← citeshttps://doi.org/10.1016/b978-0-444-63977-6.00007-9openalex-snapshot
Multivariate curve resolution for hyperspectral image analysis
inferred← citeshttps://doi.org/10.1016/b978-0-444-63984-4.00002-8openalex-snapshot
A Framework for Low-Level Data Fusion
inferred← citeshttps://doi.org/10.1016/b978-0-444-63984-4.00003-xopenalex-snapshot
General Framing of Low-, Mid-, and High-Level Data Fusion With Examples in the Life Sciences
inferred← citeshttps://doi.org/10.1016/b978-0-444-64165-6.02011-5openalex-snapshot
Multiset Data Analysis: ANOVA Simultaneous Component Analysis and Related Methods
inferred← citeshttps://doi.org/10.1016/b978-044452701-1.00054-5openalex-snapshot
Multiset Data Analysis: ANOVA Simultaneous Component Analysis and Related Methods
inferred← citeshttps://doi.org/10.1016/bs.coac.2018.07.001openalex-snapshot
An Overview of Metabolomics Data Analysis: Current Tools and Future Perspectives
inferred← citeshttps://doi.org/10.1016/bs.coac.2018.07.007openalex-snapshot
Functional Data Analysis: Omics for Environmental Risk Assessment
inferred← citeshttps://doi.org/10.1016/bs.coac.2018.08.007openalex-snapshot
ASCA: The Implementation of Design of Experiments Into Multivariate Modelling in Chemometrics
inferred← citeshttps://doi.org/10.1016/bs.coac.2018.08.008openalex-snapshot
Compression and Resolution Tools for the Analysis of Untargeted Metabolomic Data
inferred← citeshttps://doi.org/10.1016/j.ab.2020.113945openalex-snapshot
Chemometric techniques coupled with NMR for matabolic profiling of lettuce exposed to polycyclic aromatic hydrocarbones
inferred← citeshttps://doi.org/10.1016/j.aca.2008.09.024openalex-snapshot
Using ANOVA-PCA for discriminant analysis: Application to the study of mid-infrared spectra of carraghenan gels as a function of concentration and temperature
inferred← citeshttps://doi.org/10.1016/j.aca.2008.12.034openalex-snapshot
Study of the influence of micro-oxygenation and oak chip maceration on wine composition using an electronic tongue and chemical analysis
inferred← citeshttps://doi.org/10.1016/j.aca.2009.09.016openalex-snapshot
Improving the detection of significant factors using ANOVA-PCA by selective reduction of residual variability
inferred← citeshttps://doi.org/10.1016/j.aca.2009.12.003openalex-snapshot
Computational modeling of the human serum proteome response to colon resection surgery
inferred← citeshttps://doi.org/10.1016/j.aca.2009.12.042openalex-snapshot
Evaluation of the feasibility of the electronic tongue as a rapid analytical tool for wine age prediction and quantification of the organic acids and phenolic compounds. The case-study of Madeira wine
inferred← citeshttps://doi.org/10.1016/j.aca.2010.01.038openalex-snapshot
Trend analysis of time-series data: A novel method for untargeted metabolite discovery
inferred← citeshttps://doi.org/10.1016/j.aca.2011.01.008openalex-snapshot
Interpretation of analysis of variance models using principal component analysis to assess the effect of a maternal anticancer treatment on the mineralization of rat bones
inferred← citeshttps://doi.org/10.1016/j.aca.2011.12.044openalex-snapshot
Non-parametric multivariate analysis of variance in the proteomic response of potato to drought stress
inferred← citeshttps://doi.org/10.1016/j.aca.2012.04.017openalex-snapshot
Chemometric evaluation of different experimental conditions on wheat (Triticum aestivum L.) development using liquid chromatography mass spectrometry (LC–MS) profiles of benzoxazinone derivatives
inferred← citeshttps://doi.org/10.1016/j.aca.2015.02.068openalex-snapshot
Lipidomic data analysis: Tutorial, practical guidelines and applications
inferred← citeshttps://doi.org/10.1016/j.aca.2015.06.042openalex-snapshot
Regularized MANOVA (rMANOVA) in untargeted metabolomics
inferred← citeshttps://doi.org/10.1016/j.aca.2016.03.042openalex-snapshot
Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares
inferred← citeshttps://doi.org/10.1016/j.aca.2017.01.064openalex-snapshot
Combining ANOVA-PCA with POCHEMON to analyse micro-organism development in a polymicrobial environment
inferred← citeshttps://doi.org/10.1016/j.aca.2018.11.013openalex-snapshot
A two-level strategy for standardization of near infrared spectra by multi-level simultaneous component analysis
inferred← citeshttps://doi.org/10.1016/j.aca.2019.01.041openalex-snapshot
Working with log-ratios
inferred← citeshttps://doi.org/10.1016/j.aca.2019.11.050openalex-snapshot
Combining the advantages of multilevel and orthogonal partial least squares data analysis for longitudinal metabolomics: Application to kidney transplantation
inferred← citeshttps://doi.org/10.1016/j.aca.2019.12.024openalex-snapshot
Reduction of repeatability error for analysis of variance-Simultaneous Component Analysis (REP-ASCA): Application to NIR spectroscopy on coffee sample
inferred← citeshttps://doi.org/10.1016/j.aca.2020.02.025openalex-snapshot
Signature Mapping (SigMa): An efficient approach for processing complex human urine 1H NMR metabolomics data
inferred← citeshttps://doi.org/10.1016/j.aca.2020.05.059openalex-snapshot
ANOVA-Simultaneous Component analysis modelling of low-level-fused spectroscopic data: A food chemistry case-study
inferred← citeshttps://doi.org/10.1016/j.aca.2023.340824openalex-snapshot
Practical and comparative application of efficient data reduction - Multivariate curve resolution
inferred← citeshttps://doi.org/10.1016/j.aca.2023.341284openalex-snapshot
A unified strategy to rebalance multifactorial designs with unequal group sizes: application to analysis of variance multiblock orthogonal partial least squares
inferred← citeshttps://doi.org/10.1016/j.aca.2023.341716openalex-snapshot
Untargeted cannabinomics reveals the chemical differentiation of industrial hemp based on the cultivar and the geographical field location
inferred← citeshttps://doi.org/10.1016/j.aca.2024.342689openalex-snapshot
Multivariate curve resolution-based data fusion approaches applied in 1H NMR metabolomic analysis of healthy cohorts
inferred← citeshttps://doi.org/10.1016/j.aca.2025.343879openalex-snapshot
Analytical and experimental solutions for Fourier transform infrared microspectroscopy measurements of microparticles: A case study on Quercus pollen
inferred← citeshttps://doi.org/10.1016/j.aca.2026.345530openalex-snapshot
Twenty years of ASCA: a systematic review of applications for ANOVA-simultaneous component analysis
inferred← citeshttps://doi.org/10.1016/j.aca.2026.345961openalex-snapshot
Comprehensive non-targeted LC×LC-HRMS lipidomics workflow with active solvent modulation for the characterization of endocrine disruptor effects in zebrafish eleutheroembryos
inferred← citeshttps://doi.org/10.1016/j.aca.2026.346161openalex-snapshot
Finger-prick whole blood analysis via surface-enhanced Raman spectroscopy using centrifugal silver plasmonic paper substrates
inferred← citeshttps://doi.org/10.1016/j.aca.2026.346321openalex-snapshot
A comparison of PCA, ASCA, and vASCA for enhancing the interpretability of biological Raman spectroscopy
inferred← citeshttps://doi.org/10.1016/j.acax.2020.100061openalex-snapshot
ANOVA simultaneous component analysis: A tutorial review
inferred← citeshttps://doi.org/10.1016/j.afres.2024.100398openalex-snapshot
Enhancing fruity and sweet-associated aroma attributes of honeybush tea (Cyclopia spp.) by ultra-high temperature oxidation
inferred← citeshttps://doi.org/10.1016/j.animal.2026.101913openalex-snapshot
Potential of faecal NIRS for predicting methane emissions in dairy cows supplemented with 3-nitrooxypropanol
inferred← citeshttps://doi.org/10.1016/j.apsusc.2021.152325openalex-snapshot
In-depth understanding of the photoreduction of graphene oxide to reduced-graphene oxide on TiO2 surface: Statistical analysis of X-ray photoelectron and Raman spectroscopy data
inferred← citeshttps://doi.org/10.1016/j.biosystemseng.2017.03.006openalex-snapshot
Hyperspectral imaging of spinach canopy under combined water and nitrogen stress to estimate biomass, water, and nitrogen content
inferred← citeshttps://doi.org/10.1016/j.biosystemseng.2020.08.008openalex-snapshot
Using chemometrics to characterise and unravel the near infra-red spectral changes induced in aubergine fruit by chilling injury as influenced by storage time and temperature
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.03.001openalex-snapshot
Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion
inferred← citeshttps://doi.org/10.1016/j.cca.2016.12.010openalex-snapshot
Unsaturated plasma phospholipids are consistently lower in the patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 1
inferred← citeshttps://doi.org/10.1016/j.cca.2017.02.018openalex-snapshot
Tryptophan and purine metabolites are consistently upregulated in the urinary metabolome of patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 2
inferred← citeshttps://doi.org/10.1016/j.cca.2017.10.019openalex-snapshot
Metabolomics in gestational diabetes
inferred← citeshttps://doi.org/10.1016/j.chemolab.2009.04.013openalex-snapshot
Monitoring kidney-transplant patients using metabolomics and dynamic modeling
inferred← citeshttps://doi.org/10.1016/j.chemolab.2009.05.004openalex-snapshot
Exploring the analysis of structured metabolomics data
inferred← citeshttps://doi.org/10.1016/j.chemolab.2009.06.002openalex-snapshot
Self Organising Maps for variable selection: Application to human saliva analysed by nuclear magnetic resonance spectroscopy to investigate the effect of an oral healthcare product
inferred← citeshttps://doi.org/10.1016/j.chemolab.2010.05.005openalex-snapshot
Identification of significant factors by an extension of ANOVA–PCA based on multi-block analysis
inferred← citeshttps://doi.org/10.1016/j.chemolab.2010.06.004openalex-snapshot
A multiway approach to data integration in systems biology based on Tucker3 and N-PLS
inferred← citeshttps://doi.org/10.1016/j.chemolab.2010.09.001openalex-snapshot
Analysis of experimental design with multivariate response: A contribution using multiblock techniques
inferred← citeshttps://doi.org/10.1016/j.chemolab.2011.10.012openalex-snapshot
Variable selection for multifactorial genomic data
showing the first 200 of 655
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