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gargammel: a sequence simulator for ancient DNA

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1038/emboj.2009.222openalex-snapshot
The Neandertal genome and ancient DNA authenticity
inferredcites →https://doi.org/10.1038/nature13025openalex-snapshot
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
inferredcites →https://doi.org/10.1073/pnas.0704665104openalex-snapshot
Patterns of damage in genomic DNA sequences from a Neandertal
inferredcites →https://doi.org/10.1093/bioinformatics/btr708openalex-snapshot
ART: a next-generation sequencing read simulator
inferredcites →https://doi.org/10.1093/bioinformatics/btt193openalex-snapshot
mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters
inferredcites →https://doi.org/10.1093/molbev/msr048openalex-snapshot
Testing for Ancient Admixture between Closely Related Populations
inferredcites →https://doi.org/10.1093/sysbio/syw059openalex-snapshot
Evolutionary Patterns and Processes: Lessons from Ancient DNA
inferredcites →https://doi.org/10.1186/1471-2164-13-178openalex-snapshot
Improving ancient DNA read mapping against modern reference genomes
inferredcites →https://doi.org/10.1371/journal.pone.0078575openalex-snapshot
Ligation Bias in Illumina Next-Generation DNA Libraries: Implications for Sequencing Ancient Genomes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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MTaxi: A comparative tool for taxon identification of ultra low coverage ancient genomes
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MTaxi: A comparative tool for taxon identification of ultra low coverage ancient genomes
inferred← citeshttps://doi.org/10.12688/openreseurope.14936.3zenodo-depositor-declared
MTaxi: A comparative tool for taxon identification of ultra low coverage ancient genomes
inferred← citeshttps://doi.org/10.1002/9781119487845.ch10openalex-snapshot
Population Genomic Analyses of DNA from Ancient Remains
inferred← citeshttps://doi.org/10.1002/ece3.6925openalex-snapshot
Using in silico predicted ancestral genomes to improve the efficiency of paleogenome reconstruction
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An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole‐genome sequencing data
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Enriching barcoding markers in environmental samples utilizing a phylogenetic probe design: Insights from mock communities
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Ancient RNA
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Authentication and Assessment of Contamination in Ancient DNA
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Co-mutation Based Genetic Networks to Infer Temporal Mutation Dynamics in Ancient Human Mitochondrial Genomes
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Illuminating Genetic Mysteries of the Dead Sea Scrolls
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The genomic history of the Aegean palatial civilizations
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Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes
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Human inbreeding has decreased in time through the Holocene
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Probing the genomic limits of de-extinction in the Christmas Island rat
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Colonial-driven extinction of the blue antelope despite genomic adaptation to low population size
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Review: Computational analysis of human skeletal remains in ancient DNA and forensic genetics
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Do I have something in my teeth? The trouble with genetic analyses of diet from archaeological dental calculus
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Record-matching of STR profiles with fragmentary genomic SNP data
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Exploring the potential of dental calculus to shed light on past human migrations in Oceania
inferred← citeshttps://doi.org/10.1038/s41467-025-66343-1openalex-snapshot
Palaeogenomics suggest domesticated camelid herding and wild camelid hunting in early pastoralist societies in the Atacama Desert
inferred← citeshttps://doi.org/10.1038/s41467-026-72977-6openalex-snapshot
Ground squirrel coprolites preserve complex archives of ancient environmental DNA over 700,000 years
inferred← citeshttps://doi.org/10.1038/s41586-021-03532-0openalex-snapshot
Reconstruction of ancient microbial genomes from the human gut
inferred← citeshttps://doi.org/10.1038/s41586-025-09192-8openalex-snapshot
The spatiotemporal distribution of human pathogens in ancient Eurasia
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Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations
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A systematic investigation of human DNA preservation in medieval skeletons
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Assessing the impact of post-mortem damage and contamination on imputation performance in ancient DNA
inferred← citeshttps://doi.org/10.1038/s41598-024-64818-7openalex-snapshot
Metagenomic and paleopathological analyses of a historic documented collection explore ancient dental calculus as a diagnostic tool
inferred← citeshttps://doi.org/10.1038/s41598-024-82449-wopenalex-snapshot
Ancient DNA HLA typing reveals significant shifts in frequency in Europe since the Neolithic
inferred← citeshttps://doi.org/10.1038/s43586-020-00011-0openalex-snapshot
Ancient DNA analysis
inferred← citeshttps://doi.org/10.1073/pnas.2532064123openalex-snapshot
MHC-I diversity enables rapid adaptation during a viral pandemic in wild rabbit populations
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Novel approach for accurate detection of contaminating human mitochondrial DNA in next-generation sequencing data
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A broad survey of DNA sequence data simulation tools
inferred← citeshttps://doi.org/10.1093/bib/bbab076openalex-snapshot
Systematic benchmark of ancient DNA read mapping
inferred← citeshttps://doi.org/10.1093/bib/bbae646openalex-snapshot
Filtering out the noise: metagenomic classifiers optimize ancient DNA mapping
inferred← citeshttps://doi.org/10.1093/bioadv/vbag113openalex-snapshot
How low can you go? Establishing detection limits for rare eukaryotes in Southern Ocean sedimentary ancient DNA
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NGSNGS: next-generation simulator for next-generation sequencing data
inferred← citeshttps://doi.org/10.1093/bioinformatics/btae436openalex-snapshot
Unravelling reference bias in ancient DNA datasets
inferred← citeshttps://doi.org/10.1093/bioinformatics/btag004openalex-snapshot
sedimix : a workflow for the analysis of hominin nuclear DNA sequences from sediments
inferred← citeshttps://doi.org/10.1093/bioinformatics/btag155openalex-snapshot
FALCON2: compression-based metagenomic classification of ancient viruses
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz660openalex-snapshot
A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data
inferred← citeshttps://doi.org/10.1093/dnares/dsy029openalex-snapshot
ARIADNA: machine learning method for ancient DNA variant discovery
inferred← citeshttps://doi.org/10.1093/g3journal/jkaf172openalex-snapshot
Estimating allele frequencies, ancestry proportions and genotype likelihoods in the presence of mapping bias
inferred← citeshttps://doi.org/10.1093/gbe/evaf251openalex-snapshot
Mapping the Genomic Limits of De-Extinction in the Face of Ancient DNA Degradation
inferred← citeshttps://doi.org/10.1093/gigascience/giz025openalex-snapshot
DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage
inferred← citeshttps://doi.org/10.1093/molbev/msae203openalex-snapshot
soibean : High-Resolution Taxonomic Identification of Ancient Environmental DNA Using Mitochondrial Pangenome Graphs
inferred← citeshttps://doi.org/10.1093/molbev/msaf006openalex-snapshot
Read Length Dominates Phylogenetic Placement Accuracy of Ancient DNA Reads
inferred← citeshttps://doi.org/10.1093/molbev/msaf305openalex-snapshot
Quick Analysis of Sedimentary Ancient DNA Using quicksand
inferred← citeshttps://doi.org/10.1099/mgen.0.000123openalex-snapshot
Comparative scaffolding and gap filling of ancient bacterial genomes applied to two ancient Yersinia pestis genomes
inferred← citeshttps://doi.org/10.1101/2020.05.20.106971openalex-snapshot
A systematic investigation of human DNA preservation in medieval skeletons
inferred← citeshttps://doi.org/10.1101/2021.12.16.472923openalex-snapshot
Reconstructing mitochondrial genomes from ancient DNA through iterative mapping: an evaluation of software, parameters, and bait reference
inferred← citeshttps://doi.org/10.1101/2022.05.06.490351openalex-snapshot
Metagenomic analysis of coprolites from three Late Pleistocene megaherbivores from the Southwestern United States
inferred← citeshttps://doi.org/10.1101/2022.06.28.497888openalex-snapshot
Benchmarking freely available human leukocyte antigen typing algorithms across varying genes, coverages and typing resolutions
inferred← citeshttps://doi.org/10.1101/2022.12.06.519264openalex-snapshot
metaDMG – A Fast and Accurate Ancient DNA Damage Toolkit for Metagenomic Data
inferred← citeshttps://doi.org/10.1101/2023.06.15.23290026openalex-snapshot
Tracing the evolutionary path of the CCR5delta32 deletion via ancient and modern genomes
inferred← citeshttps://doi.org/10.1101/2023.07.17.549303openalex-snapshot
Benchmarking software tools for trimming adapters and merging next-generation sequencing data for ancient DNA
inferred← citeshttps://doi.org/10.1101/2023.09.28.560049openalex-snapshot
Simulation-based Benchmarking of Ancient Haplotype Inference for Detecting Population Structure
inferred← citeshttps://doi.org/10.1101/2023.10.06.561165openalex-snapshot
The spatiotemporal distribution of human pathogens in ancient Eurasia and the emergence of zoonotic diseases
inferred← citeshttps://doi.org/10.1101/2023.10.18.563027openalex-snapshot
Exploring archaeogenetic studies of dental calculus to shed light on past human migrations in Oceania
inferred← citeshttps://doi.org/10.1101/2024.01.23.576660openalex-snapshot
READv2: Advanced and user-friendly detection of biological relatedness in archaeogenomics
inferred← citeshttps://doi.org/10.1101/2024.08.09.607291openalex-snapshot
CarpeDeam: A De Novo Metagenome Assembler for Heavily Damaged Ancient Datasets
inferred← citeshttps://doi.org/10.1101/2024.09.18.613623openalex-snapshot
An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes
inferred← citeshttps://doi.org/10.1101/2025.03.31.646431openalex-snapshot
Refining filtering criteria for accurate taxonomic classification of ancient metagenomic data
inferred← citeshttps://doi.org/10.1101/2025.11.07.687203openalex-snapshot
Metagenomic classification of ancient viruses
inferred← citeshttps://doi.org/10.1101/782755openalex-snapshot
Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph
inferred← citeshttps://doi.org/10.1111/1755-0998.13009openalex-snapshot
Index hopping on the Illumina HiseqX platform and its consequences for ancient DNA studies
inferred← citeshttps://doi.org/10.1111/1755-0998.13608openalex-snapshot
A theoretical analysis of taxonomic binning accuracy
inferred← citeshttps://doi.org/10.1111/1755-0998.13960openalex-snapshot
Benchmarking kinship estimation tools for ancient genomes using pedigree simulations
inferred← citeshttps://doi.org/10.1111/1755-0998.14036openalex-snapshot
A Snakemake Toolkit for the Batch Assembly, Annotation and Phylogenetic Analysis of Mitochondrial Genomes and Ribosomal Genes From Genome Skims of Museum Collections
inferred← citeshttps://doi.org/10.1111/2041-210x.13990openalex-snapshot
Iteratively mapping ancient DNA to reconstruct highly divergent mitochondrial genomes: An evaluation of software, parameters and bait reference
inferred← citeshttps://doi.org/10.1111/2041-210x.14006openalex-snapshot
ngs LCA —A toolkit for fast and flexible lowest common ancestor inference and taxonomic profiling of metagenomic data
inferred← citeshttps://doi.org/10.1126/science.aaw8977openalex-snapshot
Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age
inferred← citeshttps://doi.org/10.1126/science.adt3880openalex-snapshot
Attenuation of virulence in Yersinia pestis across three plague pandemics
inferred← citeshttps://doi.org/10.1128/msystems.00080-18openalex-snapshot
Selection of Appropriate Metagenome Taxonomic Classifiers for Ancient Microbiome Research
inferred← citeshttps://doi.org/10.1128/msystems.01315-21openalex-snapshot
Ancient Metagenomic Studies: Considerations for the Wider Scientific Community
inferred← citeshttps://doi.org/10.1128/spectrum.02662-23openalex-snapshot
Exploring antimicrobial resistance determinants in the Neanderthal microbiome
inferred← citeshttps://doi.org/10.1146/annurev-genom-091416-035526openalex-snapshot
A Robust Framework for Microbial Archaeology
inferred← citeshttps://doi.org/10.1186/s12915-018-0581-9openalex-snapshot
Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences
inferred← citeshttps://doi.org/10.1186/s13059-019-1903-0openalex-snapshot
HOPS: automated detection and authentication of pathogen DNA in archaeological remains
inferred← citeshttps://doi.org/10.1186/s13059-020-02160-7openalex-snapshot
Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph
inferred← citeshttps://doi.org/10.1186/s13059-023-03083-9openalex-snapshot
aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
inferred← citeshttps://doi.org/10.1186/s13059-024-03350-3openalex-snapshot
READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics
inferred← citeshttps://doi.org/10.1186/s13059-024-03459-5openalex-snapshot
GenomeDelta: detecting recent transposable element invasions without repeat library
inferred← citeshttps://doi.org/10.1186/s13059-024-03462-wopenalex-snapshot
Pre-processing of paleogenomes: mitigating reference bias and postmortem damage in ancient genome data
inferred← citeshttps://doi.org/10.1186/s13059-025-03818-wopenalex-snapshot
ParaRef: a decontaminated reference database for parasite detection in ancient and modern metagenomic datasets
inferred← citeshttps://doi.org/10.1186/s13059-025-03839-5openalex-snapshot
CarpeDeam: a de novo metagenome assembler for heavily damaged ancient datasets
inferred← citeshttps://doi.org/10.1186/s13059-026-04016-yopenalex-snapshot
Evaluating the performance of ancient DNA genetic relatedness estimation methods using high-fidelity pedigree simulations
inferred← citeshttps://doi.org/10.1186/s13059-026-04242-4openalex-snapshot
COSIGT: population-scalable genotyping of complex loci from low-coverage sequencing data using pangenome graphs
inferred← citeshttps://doi.org/10.12794/metadc2356162openalex-snapshot
Towards More Robust Metagenome Profiling: Modeling and Analysis
inferred← citeshttps://doi.org/10.1360/csb-2025-5786openalex-snapshot
Adaptation and evolution of ancient organisms from an epigenetic perspective
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1010493openalex-snapshot
HAYSTAC: A Bayesian framework for robust and rapid species identification in high-throughput sequencing data
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1010788openalex-snapshot
CONGA: Copy number variation genotyping in ancient genomes and low-coverage sequencing data
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1011148openalex-snapshot
HaploCart: Human mtDNA haplogroup classification using a pangenomic reference graph
inferred← citeshttps://doi.org/10.1371/journal.pgen.1008302openalex-snapshot
The presence and impact of reference bias on population genomic studies of prehistoric human populations
inferred← citeshttps://doi.org/10.1371/journal.pone.0195491openalex-snapshot
Estimating genetic kin relationships in prehistoric populations
inferred← citeshttps://doi.org/10.1534/genetics.119.302057openalex-snapshot
Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples
inferred← citeshttps://doi.org/10.21203/rs.3.rs-9406784/v1openalex-snapshot
Imputation and Maximum Likelihood Haplotype Refinement of Simulated Ancient Mitochondrial Genomes
inferred← citeshttps://doi.org/10.3389/fbinf.2023.1260486openalex-snapshot
Benchmarking software tools for trimming adapters and merging next-generation sequencing data for ancient DNA
inferred← citeshttps://doi.org/10.3389/fevo.2020.00105openalex-snapshot
Assessing DNA Sequence Alignment Methods for Characterizing Ancient Genomes and Methylomes
inferred← citeshttps://doi.org/10.3389/fevo.2022.888421openalex-snapshot
MetaDamage tool: Examining post-mortem damage in sedaDNA on a metagenomic scale
inferred← citeshttps://doi.org/10.3389/fgene.2021.619950openalex-snapshot
New Insights Into Mitochondrial DNA Reconstruction and Variant Detection in Ancient Samples
inferred← citeshttps://doi.org/10.3389/fgene.2026.1937765openalex-snapshot
The “mobile bricks” of human evolution: how transposable elements shaped human phenotypes
inferred← citeshttps://doi.org/10.3389/fimmu.2022.987655openalex-snapshot
Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1603339openalex-snapshot
Refining filtering criteria of Kraken family of tools for accurate taxonomic profiling of ancient metagenomic data
inferred← citeshttps://doi.org/10.3390/genes14020479openalex-snapshot
Advancements and Challenges in Ancient DNA Research: Bridging the Global North–South Divide
inferred← citeshttps://doi.org/10.3390/genes9030157openalex-snapshot
Testing of Alignment Parameters for Ancient Samples: Evaluating and Optimizing Mapping Parameters for Ancient Samples Using the TAPAS Tool
inferred← citeshttps://doi.org/10.3390/microorganisms11102478openalex-snapshot
Benchmarking Metagenomic Classifiers on Simulated Ancient and Modern Metagenomic Data
inferred← citeshttps://doi.org/10.3791/63250openalex-snapshot
Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
inferred← citeshttps://doi.org/10.3791/63250-vopenalex-snapshot
Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
inferred← citeshttps://doi.org/10.47248//hpgg2404010005openalex-snapshot
Simulation-based benchmarking of ancient haplotype inference for detecting population structure
inferred← citeshttps://doi.org/10.47248/hpgg2404010001openalex-snapshot
GRUPS-rs, a high-performance ancient DNA genetic relatedness estimation software relying on pedigree simulations
inferred← citeshttps://doi.org/10.55730/1300-0152.2650openalex-snapshot
Boquila: NGS read simulator to eliminate read nucleotide bias in sequence analysis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26630542openalex-snapshot
Additional file 1 of aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
inferred← citeshttps://doi.org/10.6084/m9.figshare.26630548openalex-snapshot
Additional file 2 of aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
inferred← citeshttps://doi.org/10.6084/m9.figshare.26630551openalex-snapshot
Additional file 3 of aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
inferred← citeshttps://doi.org/10.6084/m9.figshare.26630554openalex-snapshot
Additional file 4 of aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
inferred← citeshttps://doi.org/10.6084/m9.figshare.26759471openalex-snapshot
Additional file 1 of READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics
inferred← citeshttps://doi.org/10.6084/m9.figshare.26759474openalex-snapshot
Additional file 2 of READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics
inferred← citeshttps://doi.org/10.6084/m9.figshare.26759477openalex-snapshot
Additional file 3 of READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics
inferred← citeshttps://doi.org/10.64898/2026.01.28.702372openalex-snapshot
MAT-classifier: A memory-efficient pipeline for accurate genus-level profiling from ancient metagenomic data
inferred← citeshttps://doi.org/10.64898/2026.02.05.704023openalex-snapshot
Population-scalable genotyping from low-coverage sequencing data using pangenome graphs
inferred← citeshttps://doi.org/10.64898/2026.04.20.719564openalex-snapshot
DNAharvester: A Nextflow Pipeline for Analysing Highly Degraded DNA from Ancient and Historical Specimens
inferred← citeshttps://doi.org/10.64898/2026.06.17.732633openalex-snapshot
DeepCDS: Ab initio coding sequence prediction in prokaryotic short nucleotide sequences
inferred← citeshttps://doi.org/10.64898/2026.07.03.735781openalex-snapshot
Molecular Clock Dating of Ancient Environmental DNA Reveals Damage Beyond Deamination
inferred← citeshttps://doi.org/10.64898/2026.07.15.738373openalex-snapshot
Ancient whole genomes reveal regional selection during adaptation to Neolithic lifestyle in Western Eurasia
inferred← citeshttps://doi.org/10.64898/2026.09.24.754018openalex-snapshot
SCAR: Controlled mutations, ancient DNA damage, and fragmentation of fasta and fastq sequences
inferred← citeshttps://doi.org/10.70675/772b8260z73abz4d20za3c3zac997e1a9f2fopenalex-snapshot
Phylogeny and evolution of pigeons and doves (Columbidae) at different space and time scales
inferred← citeshttps://doi.org/10.70675/afd704b6z444cz4392z8f50z1695fba1c117openalex-snapshot
Epigenomic study on the domestication of the horse using ancient DNA
inferred← citeshttps://doi.org/10.7287/peerj.11845v0.1/reviews/1openalex-snapshot
Peer Review #1 of "PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.11845v0.1/reviews/2openalex-snapshot
Peer Review #2 of "PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6594v0.1/reviews/1openalex-snapshot
Peer Review #1 of "Assessing alignment-based taxonomic classification of ancient microbial DNA (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6594v0.1/reviews/2openalex-snapshot
Peer Review #2 of "Assessing alignment-based taxonomic classification of ancient microbial DNA (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6594v0.2/reviews/1openalex-snapshot
Peer Review #1 of "Assessing alignment-based taxonomic classification of ancient microbial DNA (v0.2)"
inferred← citeshttps://doi.org/10.7287/peerj.6594v0.2/reviews/2openalex-snapshot
Peer Review #2 of "Assessing alignment-based taxonomic classification of ancient microbial DNA (v0.2)"
inferred← citeshttps://doi.org/10.7717/peerj.11845openalex-snapshot
PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly
inferred← citeshttps://doi.org/10.7717/peerj.12784openalex-snapshot
Benchmarking metagenomics classifiers on ancient viral DNA: a simulation study
inferred← citeshttps://doi.org/10.7717/peerj.16770openalex-snapshot
Benchmarking a targeted 16S ribosomal RNA gene enrichment approach to reconstruct ancient microbial communities
inferred← citeshttps://doi.org/10.7717/peerj.6594openalex-snapshot
Assessing alignment-based taxonomic classification of ancient microbial DNA
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