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Higher Striatal Iron Concentration is Linked to Frontostriatal Underactivation and Poorer Memory in Normal Aging
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Toxicity of iron and hydrogen peroxide: the Fenton reaction
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Ferritins: A family of molecules for iron storage, antioxidation and more
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Ferritin, iron homeostasis, and oxidative damage1,2 1Guest Editor: Mario Comporti 2This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal.
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Functional Brain Activation Associated with Inhibitory Control Deficits in Older Adults
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THE EFFECT OF AGE ON THE NON‐HAEMIN IRON IN THE HUMAN BRAIN
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Inflammation, Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple Sclerosis
inferredcites →https://doi.org/10.1186/1471-2202-9-102openalex-snapshot
Left inferior frontal gyrus is critical for response inhibition
inferredcites →https://doi.org/10.1196/annals.1306.017openalex-snapshot
The Relevance of Iron in the Pathogenesis of Parkinson's Disease
inferredcites →https://doi.org/10.1207/s15327906mbr4102_4openalex-snapshot
Cross-Sectional Analysis of Time-Dependent Data: Mean-Induced Association in Age-Heterogeneous Samples and an Alternative Method Based on Sequential Narrow Age-Cohort Samples
inferredcites →https://doi.org/10.1371/journal.pone.0013848openalex-snapshot
On the Role of the Striatum in Response Inhibition
inferredcites →https://doi.org/10.1371/journal.pone.0057904openalex-snapshot
Is R2* a New MRI Biomarker for the Progression of Parkinson’s Disease? A Longitudinal Follow-Up
inferredcites →https://doi.org/10.1371/journal.pone.0081419openalex-snapshot
Associations between White Matter Microstructure and Cognitive Performance in Old and Very Old Age
inferredcites →https://doi.org/10.1523/jneurosci.3617-15.2016openalex-snapshot
Iron Level and Myelin Content in the Ventral Striatum Predict Memory Performance in the Aging Brain
inferredcites →https://doi.org/10.1523/jneurosci.4717-14.2015openalex-snapshot
Striatal Iron Content Predicts Its Shrinkage and Changes in Verbal Working Memory after Two Years in Healthy Adults
inferredcites →https://doi.org/10.3389/fnagi.2013.00034openalex-snapshot
A delicate balance: Iron metabolism and diseases of the brain
inferredcites →https://doi.org/10.3389/fnmol.2015.00018openalex-snapshot
Iron entry in neurons and astrocytes: a link with synaptic activity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/nbm.4564openalex-snapshot
MRI of healthy brain aging: A review
inferred← citeshttps://doi.org/10.1002/npr2.12197openalex-snapshot
Contributions of HFE polymorphisms to brain and blood iron load, and their links to cognitive and motor function in healthy adults
inferred← citeshttps://doi.org/10.1007/978-1-0716-2799-0_13openalex-snapshot
Neuroimaging Human Dopamine-Related Neurophysiology Across Development
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Effects of lipoic acid supplementation on age- and iron-induced memory impairment, mitochondrial DNA damage and antioxidant responses
inferred← citeshttps://doi.org/10.1007/s00429-020-02032-7openalex-snapshot
A positive influence of basal ganglia iron concentration on implicit sequence learning
inferred← citeshttps://doi.org/10.1007/s11418-022-01642-1openalex-snapshot
Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3β and Nrf2/NQO1 pathways
inferred← citeshttps://doi.org/10.1007/s12035-019-01794-4openalex-snapshot
Iron Overload Impairs Autophagy: Effects of Rapamycin in Ameliorating Iron-Related Memory Deficits
inferred← citeshttps://doi.org/10.1016/b978-0-12-820480-1.00074-7openalex-snapshot
Brain iron accumulation as a biomarker of risk for cognitive decline in aging: Applications of the FRIENDS model
inferred← citeshttps://doi.org/10.1016/j.bpsc.2023.02.005openalex-snapshot
Striatal Iron Deposition in Recreational MDMA (Ecstasy) Users
inferred← citeshttps://doi.org/10.1016/j.dcn.2023.101326openalex-snapshot
Developmental coupling of brain iron and intrinsic activity in infants during the first 150 days
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Evaluation of major depressive disorder using 7 Tesla phase sensitive neuroimaging before and after mindfulness-based cognitive therapy
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2023.08.001openalex-snapshot
Multimodal imaging of microstructural cerebral alterations and loss of synaptic density in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2024.09.004openalex-snapshot
Lifestyle, biological, and genetic factors related to brain iron accumulation across adulthood
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.08.036openalex-snapshot
Functional coherence of striatal resting-state networks is modulated by striatal iron content
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2020.116544openalex-snapshot
Striatal iron content is linked to reduced fronto-striatal brain function under working memory load
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2020.117309openalex-snapshot
Cortical iron disrupts functional connectivity networks supporting working memory performance in older adults
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2021.117792openalex-snapshot
Elevated neuroinflammation contributes to the deleterious impact of iron overload on brain function in aging
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.120323openalex-snapshot
The iron-dopamine D1 coupling modulates neural signatures of working memory across adult lifespan
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.120478openalex-snapshot
Iron content affects age group differences in associative learning-related fMRI activity
inferred← citeshttps://doi.org/10.1016/j.nicl.2025.103866openalex-snapshot
Mapping iron content and white matter integrity in the anterior thalamic radiations across Huntington’s disease stages
inferred← citeshttps://doi.org/10.1021/acs.accounts.9b00248openalex-snapshot
Metal Ions in Alzheimer’s Disease: A Key Role or Not?
inferred← citeshttps://doi.org/10.1021/acschemneuro.3c00343openalex-snapshot
Ferroptosis, Pyroptosis, and Cuproptosis in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1038/s41398-018-0232-5openalex-snapshot
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload
inferred← citeshttps://doi.org/10.1038/s41598-021-88840-1openalex-snapshot
Age-related iron accumulation and demyelination in the basal ganglia are closely related to verbal memory and executive functioning
inferred← citeshttps://doi.org/10.1101/2023.04.14.23288516openalex-snapshot
Multimodal imaging of microstructural cerebral changes and loss of synaptic density in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1111/ejn.15838openalex-snapshot
Cognition and brain iron deposition in whole grey matter regions and hippocampal subfields
inferred← citeshttps://doi.org/10.1162/imag_a_00304openalex-snapshot
Automated segmentation of midbrain nuclei using deep learning and multisequence MRI: A longitudinal study on iron accumulation with age
inferred← citeshttps://doi.org/10.1177/0269881119875979openalex-snapshot
Sex influences in the preventive effects of N-acetylcysteine in a two-hit animal model of schizophrenia
inferred← citeshttps://doi.org/10.1212/wnl.0000000000010868openalex-snapshot
Contribution of iron and Aβ to age differences in entorhinal and hippocampal subfield volume
inferred← citeshttps://doi.org/10.1371/journal.pone.0240697openalex-snapshot
The impact of brain iron accumulation on cognition: A systematic review
inferred← citeshttps://doi.org/10.14336/ad.2019.0064openalex-snapshot
Association between Body Iron Status and Cognitive Task Performance in a Nationally Representative Sample of Older Adults
inferred← citeshttps://doi.org/10.1684/nrp.2018.0465openalex-snapshot
Accumulation de fer dans le cerveau et déclin moteur et cognitif dans le vieillissement normal
inferred← citeshttps://doi.org/10.21007/etd.cghs.2020.0525openalex-snapshot
Systems Genetics and Systems Biology Analysis of Paraquat Effects in BXD Recombinant Inbred Mice
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Quantitative susceptibility mapping to evaluate brain iron deposition and its correlation with physiological parameters in hypertensive patients
inferred← citeshttps://doi.org/10.21037/qims-21-87openalex-snapshot
Age-related magnetic susceptibility changes in deep grey matter and cerebral cortex of normal young and middle-aged adults depicted by whole brain analysis
inferred← citeshttps://doi.org/10.31234/osf.io/v7m6gopenalex-snapshot
Iron content affects age group differences in associative learning-related fMRI activity
inferred← citeshttps://doi.org/10.31234/osf.io/vwxbtopenalex-snapshot
Iron content affects age group differences in associative learning-related fMRI activity
inferred← citeshttps://doi.org/10.32469/10355/97056openalex-snapshot
Evaluating the molecular drivers of physical inactivity and muscle atrophy as initiating factors in cognitive impairment
inferred← citeshttps://doi.org/10.3389/fnhum.2022.838228openalex-snapshot
Contributions of the Catechol-O-Methyltransferase Val158Met Polymorphism to Changes in Brain Iron Across Adulthood and Their Relationships to Working Memory
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Iron Deposition in Brain: Does Aging Matter?
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