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Insular and Ventrolateral Orbitofrontal Cortices Differentially Contribute to Goal-Directed Behavior in Rodents

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Cortical, thalamic, and amygdaloid connections of the anterior and posterior insular cortices

inferredcites →https://doi.org/10.1002/cne.22733openalex-snapshot

Projections of the medial orbital and ventral orbital cortex in the rat

inferredcites →https://doi.org/10.1002/cne.903520407openalex-snapshot

Afferent connections of the medial frontal cortex of the rat. II. Cortical and subcortical afferents

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Differential projections of the infralimbic and prelimbic cortex in the rat

inferredcites →https://doi.org/10.1007/978-1-4939-1096-0_14openalex-snapshot

Acute Brain Slice Methods for Adult and Aging Animals: Application of Targeted Patch Clamp Analysis and Optogenetics

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Limbic lesions and the problem of stimulus—Reinforcement associations

inferredcites →https://doi.org/10.1016/0301-0082(84)90007-8openalex-snapshot

Taste responses of cortical neurons

inferredcites →https://doi.org/10.1016/j.bbr.2003.09.023openalex-snapshot

The role of prelimbic cortex in instrumental conditioning

inferredcites →https://doi.org/10.1016/j.biopsych.2015.10.026openalex-snapshot

Connections of the Mouse Orbitofrontal Cortex and Regulation of Goal-Directed Action Selection by Brain-Derived Neurotrophic Factor

inferredcites →https://doi.org/10.1016/j.brainres.2003.08.056openalex-snapshot

Areal and synaptic interconnectivity of prelimbic (area 32), infralimbic (area 25) and insular cortices in the rat

inferredcites →https://doi.org/10.1016/j.conb.2012.04.001openalex-snapshot

Neural processing of gustatory information in insular circuits

inferredcites →https://doi.org/10.1016/j.neuron.2005.02.018openalex-snapshot

Rapid Associative Encoding in Basolateral Amygdala Depends on Connections with Orbitofrontal Cortex

inferredcites →https://doi.org/10.1016/j.neuron.2005.07.018openalex-snapshot

Orbitofrontal Cortex, Associative Learning, and Expectancies

inferredcites →https://doi.org/10.1016/j.neuron.2007.07.022openalex-snapshot

Contributions of the Amygdala to Reward Expectancy and Choice Signals in Human Prefrontal Cortex

inferredcites →https://doi.org/10.1016/j.neuron.2012.02.031openalex-snapshot

Effects of Cue-Triggered Expectation on Cortical Processing of Taste

inferredcites →https://doi.org/10.1016/j.neuron.2013.04.039openalex-snapshot

The Thalamostriatal Pathway and Cholinergic Control of Goal-Directed Action: Interlacing New with Existing Learning in the Striatum

inferredcites →https://doi.org/10.1016/j.neuron.2013.09.007openalex-snapshot

Goals and Habits in the Brain

inferredcites →https://doi.org/10.1016/j.neuron.2013.09.036openalex-snapshot

Effects of Amygdala Lesions on Reward-Value Coding in Orbital and Medial Prefrontal Cortex

inferredcites →https://doi.org/10.1016/j.neuron.2013.11.005openalex-snapshot

Orbitofrontal Cortex as a Cognitive Map of Task Space

inferredcites →https://doi.org/10.1016/j.neuron.2015.10.044openalex-snapshot

Medial Orbitofrontal Cortex Mediates Outcome Retrieval in Partially Observable Task Situations

inferredcites →https://doi.org/10.1016/j.neuron.2016.04.043openalex-snapshot

Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation

inferredcites →https://doi.org/10.1016/j.neuroscience.2009.09.073openalex-snapshot

Spatiotemporal dynamics of excitation in rat insular cortex: intrinsic corticocortical circuit regulates caudal-rostro excitatory propagation from the insular to frontal cortex

inferredcites →https://doi.org/10.1016/j.nlm.2004.10.003openalex-snapshot

The involvement of the orbitofrontal cortex in learning under changing task contingencies

inferredcites →https://doi.org/10.1016/j.nlm.2014.01.001openalex-snapshot

The forgotten insular cortex: Its role on recognition memory formation

inferredcites →https://doi.org/10.1016/j.nlm.2015.12.005openalex-snapshot

Acquisition of specific response–outcome associations requires NMDA receptor activation in the basolateral amygdala but not in the insular cortex

inferredcites →https://doi.org/10.1016/j.physbeh.2012.03.009openalex-snapshot

Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies

inferredcites →https://doi.org/10.1016/j.tics.2005.12.002openalex-snapshot

Primate orbitofrontal cortex and adaptive behaviour

inferredcites →https://doi.org/10.1016/s0028-3908(98)00033-1openalex-snapshot

Goal-directed instrumental action: contingency and incentive learning and their cortical substrates

inferredcites →https://doi.org/10.1016/s0306-4522(98)00360-1openalex-snapshot

Blockade of N-methyl-d-aspartate receptors in the insular cortex disrupts taste aversion and spatial memory formation

inferredcites →https://doi.org/10.1037/0735-7044.119.1.317openalex-snapshot

Orbitofrontal Lesions Impair Use of Cue-Outcome Associations in a Devaluation Task.

inferredcites →https://doi.org/10.1037/10291-000openalex-snapshot

Why we eat what we eat: The psychology of eating.

inferredcites →https://doi.org/10.1037/a0029080openalex-snapshot

Transient inactivation of basolateral amygdala during selective satiation disrupts reinforcer devaluation in rats.

inferredcites →https://doi.org/10.1038/ncomms3264openalex-snapshot

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

inferredcites →https://doi.org/10.1038/nn.4269openalex-snapshot

Thalamus plays a central role in ongoing cortical functioning

inferredcites →https://doi.org/10.1038/npp.2009.131openalex-snapshot

Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action

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A framework for studying the neurobiology of value-based decision making

inferredcites →https://doi.org/10.1046/j.1460-9568.2002.02174.xopenalex-snapshot

Differential involvement of cortical muscarinic and NMDA receptors in short‐ and long‐term taste aversion memory

inferredcites →https://doi.org/10.1073/pnas.0700293104openalex-snapshot

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

inferredcites →https://doi.org/10.1073/pnas.0905874106openalex-snapshot

Distinct opioid circuits determine the palatability and the desirability of rewarding events

inferredcites →https://doi.org/10.1073/pnas.1416573112openalex-snapshot

Central role for the insular cortex in mediating conditioned responses to anticipatory cues

inferredcites →https://doi.org/10.1093/cercor/13.4.400openalex-snapshot

Coordination of Actions and Habits in the Medial Prefrontal Cortex of Rats

inferredcites →https://doi.org/10.1097/00001756-200205070-00030openalex-snapshot

Orbitofrontal lesions in rats impair reversal but not acquisition of go, no-go odor discriminations

inferredcites →https://doi.org/10.1098/rstb.1985.0010openalex-snapshot

Actions and habits: the development of behavioural autonomy

inferredcites →https://doi.org/10.1101/lm.55203openalex-snapshot

Lesions of Orbitofrontal Cortex and Basolateral Amygdala Complex Disrupt Acquisition of Odor-Guided Discriminations and Reversals

inferredcites →https://doi.org/10.1111/j.1460-9568.2007.05525.xopenalex-snapshot

The effects of selective amygdala, orbital frontal cortex or hippocampal formation lesions on reward assessment in nonhuman primates

inferredcites →https://doi.org/10.1111/j.1460-9568.2009.06834.xopenalex-snapshot

Transient role of the rat prelimbic cortex in goal‐directed behaviour

inferredcites →https://doi.org/10.1111/j.1460-9568.2010.07153.xopenalex-snapshot

Posterior dorsomedial striatum is critical for both selective instrumental and Pavlovian reward learning

inferredcites →https://doi.org/10.1111/j.1749-6632.2011.06229.xopenalex-snapshot

Orbitofrontal contributions to value‐based decision making: evidence from humans with frontal lobe damage

inferredcites →https://doi.org/10.1111/j.1749-6632.2011.06270.xopenalex-snapshot

The orbitofrontal cortex, predicted value, and choice

inferredcites →https://doi.org/10.1111/j.1753-4887.1986.tb07593.xopenalex-snapshot

Sensory-specific Satiety

inferredcites →https://doi.org/10.1124/pr.110.003020openalex-snapshot

Remote Control of Neuronal Signaling

inferredcites →https://doi.org/10.1152/jn.00968.2003openalex-snapshot

Combined Unilateral Lesions of the Amygdala and Orbital Prefrontal Cortex Impair Affective Processing in Rhesus Monkeys

inferredcites →https://doi.org/10.1162/jocn.1995.7.1.1openalex-snapshot

Do Rats Have Prefrontal Cortex? The Rose-Woolsey-Akert Program Reconsidered

inferredcites →https://doi.org/10.1196/annals.1401.033openalex-snapshot

The Contribution of Orbitofrontal Cortex to Action Selection

inferredcites →https://doi.org/10.1523/jneurosci.0157-16.2016openalex-snapshot

Cholinergic Interneurons Use Orbitofrontal Input to Track Beliefs about Current State

inferredcites →https://doi.org/10.1523/jneurosci.0796-16.2016openalex-snapshot

Choice Behavior Guided by Learned, But Not Innate, Taste Aversion Recruits the Orbitofrontal Cortex

inferredcites →https://doi.org/10.1523/jneurosci.1237-15.2015openalex-snapshot

Flexible Use of Predictive Cues beyond the Orbitofrontal Cortex: Role of the Submedius Thalamic Nucleus

inferredcites →https://doi.org/10.1523/jneurosci.17-23-09285.1997openalex-snapshot

Dissociable Forms of Inhibitory Control within Prefrontal Cortex with an Analog of the Wisconsin Card Sort Test: Restriction to Novel Situations and Independence from “On-Line” Processing

inferredcites →https://doi.org/10.1523/jneurosci.1772-16.2016openalex-snapshot

Consolidation of Goal-Directed Action Depends on MAPK/ERK Signaling in Rodent Prelimbic Cortex

inferredcites →https://doi.org/10.1523/jneurosci.1820-14.2014openalex-snapshot

Encoding and Tracking of Outcome-Specific Expectancy in the Gustatory Cortex of Alert Rats

inferredcites →https://doi.org/10.1523/jneurosci.1839-16.2017openalex-snapshot

The Role of Orbitofrontal–Amygdala Interactions in Updating Action–Outcome Valuations in Macaques

inferredcites →https://doi.org/10.1523/jneurosci.19-15-06610.1999openalex-snapshot

Orbitofrontal Cortex and Representation of Incentive Value in Associative Learning

inferredcites →https://doi.org/10.1523/jneurosci.1921-04.2004openalex-snapshot

Bilateral Orbital Prefrontal Cortex Lesions in Rhesus Monkeys Disrupt Choices Guided by Both Reward Value and Reward Contingency

inferredcites →https://doi.org/10.1523/jneurosci.1921-05.2005openalex-snapshot

Lesions of Medial Prefrontal Cortex Disrupt the Acquisition But Not the Expression of Goal-Directed Learning

inferredcites →https://doi.org/10.1523/jneurosci.20-23-08954.2000openalex-snapshot

The Effect of Lesions of the Insular Cortex on Instrumental Conditioning: Evidence for a Role in Incentive Memory

inferredcites →https://doi.org/10.1523/jneurosci.2272-08.2008openalex-snapshot

Amygdala and Orbitofrontal Cortex Lesions Differentially Influence Choices during Object Reversal Learning

inferredcites →https://doi.org/10.1523/jneurosci.23-25-08771.2003openalex-snapshot

Dissociable Contributions of the Orbitofrontal and Infralimbic Cortex to Pavlovian Autoshaping and Discrimination Reversal Learning: Further Evidence for the Functional Heterogeneity of the Rodent Frontal Cortex

inferredcites →https://doi.org/10.1523/jneurosci.23-35-11078.2003openalex-snapshot

Different Roles for Orbitofrontal Cortex and Basolateral Amygdala in a Reinforcer Devaluation Task

inferredcites →https://doi.org/10.1523/jneurosci.3126-15.2015openalex-snapshot

Neural Estimates of Imagined Outcomes in Basolateral Amygdala Depend on Orbitofrontal Cortex

inferredcites →https://doi.org/10.1523/jneurosci.3271-13.2013openalex-snapshot

The Role of the Amygdala-Striatal Pathway in the Acquisition and Performance of Goal-Directed Instrumental Actions

inferredcites →https://doi.org/10.1523/jneurosci.3295-11.2011openalex-snapshot

Transient Inactivation of Orbitofrontal Cortex Blocks Reinforcer Devaluation in Macaques

inferredcites →https://doi.org/10.1523/jneurosci.3541-08.2008openalex-snapshot

Frontal Cortex Subregions Play Distinct Roles in Choices between Actions and Stimuli

inferredcites →https://doi.org/10.1523/jneurosci.3795-09.2010openalex-snapshot

Functional Interaction of Medial Mediodorsal Thalamic Nucleus But Not Nucleus Accumbens with Amygdala and Orbital Prefrontal Cortex Is Essential for Adaptive Response Selection after Reinforcer Devaluation

inferredcites →https://doi.org/10.1523/jneurosci.3971-12.2013openalex-snapshot

Functional Disconnection of the Orbitofrontal Cortex and Basolateral Amygdala Impairs Acquisition of a Rat Gambling Task and Disrupts Animals' Ability to Alter Decision-Making Behavior after Reinforcer Devaluation

inferredcites →https://doi.org/10.1523/jneurosci.4153-14.2015openalex-snapshot

Interaction of Insular Cortex and Ventral Striatum Mediates the Effect of Incentive Memory on Choice Between Goal-Directed Actions

inferredcites →https://doi.org/10.1523/jneurosci.4253-15.2016openalex-snapshot

The Medial Orbitofrontal Cortex Regulates Sensitivity to Outcome Value

inferredcites →https://doi.org/10.1523/jneurosci.4374-12.2013openalex-snapshot

Differential Effects of Amygdala, Orbital Prefrontal Cortex, and Prelimbic Cortex Lesions on Goal-Directed Behavior in Rhesus Macaques

inferredcites →https://doi.org/10.1523/jneurosci.4920-12.2013openalex-snapshot

Choice Coding in Frontal Cortex during Stimulus-Guided or Action-Guided Decision-Making

inferredcites →https://doi.org/10.1523/jneurosci.5071-12.2013openalex-snapshot

Incentive Memory: Evidence the Basolateral Amygdala Encodes and the Insular Cortex Retrieves Outcome Values to Guide Choice between Goal-Directed Actions

inferredcites →https://doi.org/10.1523/jneurosci.5443-06.2007openalex-snapshot

Orbitofrontal Cortex Mediates Outcome Encoding in Pavlovian But Not Instrumental Conditioning

inferredcites →https://doi.org/10.3389/fnins.2013.00112openalex-snapshot

The drive to strive: goal generation based on current needs

inferredcites →https://doi.org/10.3389/neuro.01.030.2008openalex-snapshot

High on habits

inferredcites →https://doi.org/10.3758/s13420-012-0080-8openalex-snapshot

Exploring a latent cause theory of classical conditioning

inferredcites →https://doi.org/10.3758/s13420-016-0226-1openalex-snapshot

A time course analysis of satiety-induced instrumental outcome devaluation

inferredcites →https://doi.org/10.5860/choice.34-5380openalex-snapshot

Why we eat what we eat: the psychology of eating

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4554595openalex-extracted

A Hippocampo-Cortical Pathway Detects Changes in the Validity of an Action as a Predictor of Reward

inferred← citeshttps://doi.org/10.1002/hipo.23167openalex-snapshot

Learning, memory and consolidation mechanisms for behavioral control in hierarchically organized cortico‐basal ganglia systems

inferred← citeshttps://doi.org/10.1002/jnr.24567openalex-snapshot

Involvement of the rodent prelimbic and medial orbitofrontal cortices in goal‐directed action: A brief review

inferred← citeshttps://doi.org/10.1002/npr2.12209openalex-snapshot

Pharmacologically induced N‐methyl‐D‐aspartate receptor hypofunction impairs goal‐directed food seeking in rats

inferred← citeshttps://doi.org/10.1007/978-1-0716-2799-0_14openalex-snapshot

Dopaminergic Control of Actions and Habits

inferred← citeshttps://doi.org/10.1007/978-3-031-55889-4_8openalex-snapshot

Prefrontal Control of Actions and Habits

inferred← citeshttps://doi.org/10.1007/s00213-023-06352-4openalex-snapshot

Long-term effects of THC exposure on reward learning and motivated behavior in adolescent and adult male rats

inferred← citeshttps://doi.org/10.1007/s13311-019-00752-1openalex-snapshot

Action-Outcome Expectancies Require Orbitofrontal Neurotrophin Systems in Naïve and Cocaine-Exposed Mice

inferred← citeshttps://doi.org/10.1016/b978-0-12-812098-9.00008-5openalex-snapshot

Cortical Determinants of Goal-Directed Behavior

inferred← citeshttps://doi.org/10.1016/b978-0-12-820480-1.00001-2openalex-snapshot

Outcome-specific reward processing and decision-making

inferred← citeshttps://doi.org/10.1016/j.bbr.2019.112159openalex-snapshot

Pre-training inactivation of basolateral amygdala and mediodorsal thalamus, but not orbitofrontal cortex or prelimbic cortex, impairs devaluation in a multiple-response/multiple-reinforcer cued operant task

inferred← citeshttps://doi.org/10.1016/j.bbr.2023.114761openalex-snapshot

Impairments in expression of devaluation in a Pavlovian goal-tracking task, but not a free operant devaluation task, after fentanyl exposure in female rats

inferred← citeshttps://doi.org/10.1016/j.beproc.2018.10.014openalex-snapshot

Discretion for behavioral selection affects development of habit formation after extended training in rats

inferred← citeshttps://doi.org/10.1016/j.biopsych.2020.07.022openalex-snapshot

The Basolateral Amygdala to Nucleus Accumbens Core Circuit Mediates the Conditioned Reinforcing Effects of Cocaine-Paired Cues on Cocaine Seeking

inferred← citeshttps://doi.org/10.1016/j.biopsych.2022.02.008openalex-snapshot

A Novel Insular/Orbital-Prelimbic Circuit That Prevents Persistent Avoidance in a Rodent Model of Compulsive Behavior

inferred← citeshttps://doi.org/10.1016/j.biopsych.2022.08.028openalex-snapshot

Computationally Informed Interventions for Targeting Compulsive Behaviors

inferred← citeshttps://doi.org/10.1016/j.brainres.2022.147885openalex-snapshot

Insula lesions reduce stimulus-driven control of behavior during odor-guided decision-making and autoshaping

inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111334openalex-snapshot

Medial orbitofrontal neurotrophin systems integrate hippocampal input into outcome-specific value representations

inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117105openalex-snapshot

Orbitofrontal noradrenaline acts as an early gate for reversal learning

inferred← citeshttps://doi.org/10.1016/j.cobeha.2021.02.004openalex-snapshot

Neural circuits for inference-based decision-making

inferred← citeshttps://doi.org/10.1016/j.cobeha.2021.02.011openalex-snapshot

Is the core function of orbitofrontal cortex to signal values or make predictions?

inferred← citeshttps://doi.org/10.1016/j.cub.2019.10.058openalex-snapshot

Real-Time Value Integration during Economic Choice Is Regulated by Orbitofrontal Cortex

inferred← citeshttps://doi.org/10.1016/j.cub.2022.09.022openalex-snapshot

Orbitofrontal cortex populations are differentially recruited to support actions

inferred← citeshttps://doi.org/10.1016/j.cub.2023.11.036openalex-snapshot

A hippocampo-cortical pathway detects changes in the validity of an action as a predictor of reward

inferred← citeshttps://doi.org/10.1016/j.cub.2025.07.083openalex-snapshot

Orbitofrontal cortex spontaneously recovers latent information about outcomes upon devaluation

inferred← citeshttps://doi.org/10.1016/j.isci.2024.110148openalex-snapshot

Cocaine disrupts action flexibility via glucocorticoid receptors

inferred← citeshttps://doi.org/10.1016/j.jchemneu.2019.01.002openalex-snapshot

Distinct regional patterns in noradrenergic innervation of the rat prefrontal cortex

inferred← citeshttps://doi.org/10.1016/j.nbd.2026.107561openalex-snapshot

Neuromodulators of orbitofrontal cortex function: A review of endocannabinoid, neurotrophin, and cell adhesion systems

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2019.11.009openalex-snapshot

Rodent medial and lateral orbitofrontal cortices represent unique components of cognitive maps of task space

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2020.07.010openalex-snapshot

Prefrontal regulation of behavioural control: Evidence from learning theory and translational approaches in rodents

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2020.09.030openalex-snapshot

Adaptive behaviour under conflict: Deconstructing extinction, reversal, and active avoidance learning

inferred← citeshttps://doi.org/10.1016/j.neuint.2019.104464openalex-snapshot

Neural circuits in goal-directed and habitual behavior: Implications for circuit dysfunction in obsessive-compulsive disorder

inferred← citeshttps://doi.org/10.1016/j.neuron.2019.09.024openalex-snapshot

The Meaning of Behavior: Discriminating Reflex and Volition in the Brain

inferred← citeshttps://doi.org/10.1016/j.neuron.2020.08.010openalex-snapshot

Processing in Lateral Orbitofrontal Cortex Is Required to Estimate Subjective Preference during Initial, but Not Established, Economic Choice

inferred← citeshttps://doi.org/10.1016/j.neuron.2021.06.003openalex-snapshot

Controlling one’s world: Identification of sub-regions of primate PFC underlying goal-directed behavior

inferred← citeshttps://doi.org/10.1016/j.nlm.2018.09.008openalex-snapshot

Inferring action-dependent outcome representations depends on anterior but not posterior medial orbitofrontal cortex

inferred← citeshttps://doi.org/10.1016/j.nlm.2026.108187openalex-snapshot

Chemogenetic disruption of the hippocampus impairs gustatory preconditioning in rats

inferred← citeshttps://doi.org/10.1016/j.pnpbp.2017.09.003openalex-snapshot

Behavioral and neural mechanisms underlying habitual and compulsive drug seeking

inferred← citeshttps://doi.org/10.1016/j.psyneuen.2019.104436openalex-snapshot

Glucocorticoid-sensitive ventral hippocampal-orbitofrontal cortical connections support goal-directed action – Curt Richter Award Paper 2019

inferred← citeshttps://doi.org/10.1016/j.ynstr.2020.100274openalex-snapshot

Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress

inferred← citeshttps://doi.org/10.1017/s003329172000402xopenalex-snapshot

Blunted reward prediction error signals in internet gaming disorder

inferred← citeshttps://doi.org/10.1037/bne0000401openalex-snapshot

Cross-species studies on orbitofrontal control of inference-based behavior.

inferred← citeshttps://doi.org/10.1037/bne0000426openalex-snapshot

Dopamine and noradrenaline modulation of goal-directed behavior in orbital and medial prefrontal cortex: Toward a division of labor?

inferred← citeshttps://doi.org/10.1037/bne0000442openalex-snapshot

Defining an orbitofrontal compass: Functional and anatomical heterogeneity across anterior–posterior and medial–lateral axes.

inferred← citeshttps://doi.org/10.1037/bne0000443openalex-snapshot

Does disrupting the orbitofrontal cortex alter sensitivity to punishment? A potential mechanism of compulsivity.

inferred← citeshttps://doi.org/10.1037/bne0000450openalex-snapshot

Call for a more balanced approach to understanding orbital frontal cortex function.

inferred← citeshttps://doi.org/10.1037/bne0000455openalex-snapshot

To be specific: The role of orbitofrontal cortex in signaling reward identity.

inferred← citeshttps://doi.org/10.1037/bne0000463openalex-snapshot

The orbitofrontal cartographer.

inferred← citeshttps://doi.org/10.1038/s41386-019-0498-1openalex-snapshot

Linking actions with their consequences within the ventrolateral orbital cortex

inferred← citeshttps://doi.org/10.1038/s41386-022-01437-8openalex-snapshot

GluN2B inhibition confers resilience against long-term cocaine-induced neurocognitive sequelae

inferred← citeshttps://doi.org/10.1038/s41583-020-0289-zopenalex-snapshot

The transition to compulsion in addiction

inferred← citeshttps://doi.org/10.1038/s41593-022-01148-9openalex-snapshot

A molecularly integrated amygdalo-fronto-striatal network coordinates flexible learning and memory

inferred← citeshttps://doi.org/10.1038/s41593-022-01210-6openalex-snapshot

Disinhibition of the orbitofrontal cortex biases decision-making in obesity

inferred← citeshttps://doi.org/10.1038/s41593-023-01409-1openalex-snapshot

Orbitofrontal cortex control of striatum leads economic decision-making

inferred← citeshttps://doi.org/10.1038/s41598-024-84369-1openalex-snapshot

Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei

inferred← citeshttps://doi.org/10.1073/pnas.2536535123openalex-snapshot

Orbitofrontal noradrenaline supports adaptive learning-rate adjustment in probabilistic reversal learning

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.001.0001openalex-snapshot

The Neuropsychology of Anxiety

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0004openalex-snapshot

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0005openalex-snapshot

Dedication

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0006openalex-snapshot

Preface

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0009openalex-snapshot

Abbreviations

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0010openalex-snapshot

List of online appendices and reviews

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.002.0011openalex-snapshot

Epigraph

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0001openalex-snapshot

Overview

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0002openalex-snapshot

Ethology and anxiety

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0003openalex-snapshot

Learning theory and anxiety

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0004openalex-snapshot

The anxiolytic drugs—our key tool

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0005openalex-snapshot

A conceptual theory of the goal inhibition system

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0006openalex-snapshot

The neurology of anxiety—survival circuits

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0007openalex-snapshot

What do hippocampal cell fields represent?

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0008openalex-snapshot

Memory and the septo-hippocampal system

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0009openalex-snapshot

Fundamentals of the septo-hippocampal system

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0010openalex-snapshot

A theory of the septo-hippocampal system (SHS)

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0011openalex-snapshot

The neurology of anxiety—planning circuits

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0012openalex-snapshot

Anxiety and personality

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0013openalex-snapshot

Symptoms and syndromes of anxiety

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0014openalex-snapshot

The treatment of anxiety and fear disorders

inferred← citeshttps://doi.org/10.1093/oso/9780198843313.003.0015openalex-snapshot

Coda

inferred← citeshttps://doi.org/10.1101/2020.04.24.059808openalex-snapshot

Targeted stimulation of an orbitofrontal network disrupts decisions based on inferred, not experienced outcomes

inferred← citeshttps://doi.org/10.1101/2021.04.20.440613openalex-snapshot

Training-Induced Circuit-Specific Excitatory Synaptogenesis is Required for Effort Control

inferred← citeshttps://doi.org/10.1101/2021.09.10.459813openalex-snapshot

BRAIN-DERIVED NEUROTROPHIC FACTOR IN AN ORBITOFRONTAL CORTICAL-DORSOLATERAL STRIATAL CIRCUIT GATES ALCOHOL CONSUMPTION

inferred← citeshttps://doi.org/10.1101/2022.02.24.481881openalex-snapshot

Basolateral amygdala to insular cortex activity makes sign-tracking behavior insensitive to outcome value

inferred← citeshttps://doi.org/10.1101/2022.09.29.510151openalex-snapshot

Orbitofrontal Cortex is necessary for the behavioural expression, but not learning, of Pavlovian conditioned inhibition

inferred← citeshttps://doi.org/10.1101/2024.10.10.617625openalex-snapshot

Contribution of rat insular cortex to stimulus-guided action

inferred← citeshttps://doi.org/10.1101/391342openalex-snapshot

Sucrose intensity coding and decision-making in rat gustatory cortices

inferred← citeshttps://doi.org/10.1111/acer.14441openalex-snapshot

Review of Orbitofrontal Cortex in Alcohol Dependence: A Disrupted Cognitive Map?

inferred← citeshttps://doi.org/10.1111/ejn.13689openalex-snapshot

The anterior insula bidirectionally modulates cost‐benefit decision‐making on a rodent gambling task

inferred← citeshttps://doi.org/10.1146/annurev-psych-010418-102824openalex-snapshot

An Integrated Model of Action Selection: Distinct Modes of Cortical Control of Striatal Decision Making

inferred← citeshttps://doi.org/10.1371/journal.pbio.3000605openalex-snapshot

Behavioral flexibility is associated with changes in structure and function distributed across a frontal cortical network in macaques

inferred← citeshttps://doi.org/10.1371/journal.pcbi.1010500openalex-snapshot

Thalamic regulation of frontal interactions in human cognitive flexibility

inferred← citeshttps://doi.org/10.1523/eneuro.0156-22.2022openalex-snapshot

Inactivation of the Basolateral Amygdala to Insular Cortex Pathway Makes Sign-Tracking Sensitive to Outcome Devaluation

inferred← citeshttps://doi.org/10.1523/eneuro.0318-19.2019openalex-snapshot

Social Isolation in Adolescence Disrupts Cortical Development and Goal-Dependent Decision-Making in Adulthood, Despite Social Reintegration

inferred← citeshttps://doi.org/10.1523/jneurosci.0078-24.2024openalex-snapshot

Adaptive Responding to Stimulus–Outcome Associations Requires Noradrenergic Transmission in the Medial Prefrontal Cortex

inferred← citeshttps://doi.org/10.1523/jneurosci.0781-20.2021openalex-snapshot

Cell Adhesion Factors in the Orbitofrontal Cortex Control Cue-Induced Reinstatement of Cocaine Seeking and Amygdala-Dependent Goal Seeking

inferred← citeshttps://doi.org/10.1523/jneurosci.1678-17.2017openalex-snapshot

Functional Heterogeneity within Rat Orbitofrontal Cortex in Reward Learning and Decision Making

inferred← citeshttps://doi.org/10.1523/jneurosci.1680-20.2020openalex-snapshot

Targeted Stimulation of an Orbitofrontal Network Disrupts Decisions Based on Inferred, Not Experienced Outcomes

inferred← citeshttps://doi.org/10.1523/jneurosci.1923-24.2025openalex-snapshot

Contribution of Rat Insular Cortex to Stimulus-Guided Action

inferred← citeshttps://doi.org/10.1523/jneurosci.3072-18.2019openalex-snapshot

β1-Integrins in the Developing Orbitofrontal Cortex Are Necessary for Expectancy Updating in Mice

inferred← citeshttps://doi.org/10.31234/osf.io/gt5fdopenalex-snapshot

Dopamine and noradrenaline modulation of goal-directed behaviour in prefrontal areas: Toward a division of labour?

inferred← citeshttps://doi.org/10.31234/osf.io/nzjm9openalex-snapshot

Is the core function of orbitofrontal cortex to signal values or make predictions?

inferred← citeshttps://doi.org/10.31234/osf.io/tk5gnopenalex-snapshot

Medial and lateral orbitofrontal cortices represent unique components of cognitive maps of task space

inferred← citeshttps://doi.org/10.3389/fnbeh.2021.655029openalex-snapshot

Parafascicular Thalamic and Orbitofrontal Cortical Inputs to Striatum Represent States for Goal-Directed Action Selection

inferred← citeshttps://doi.org/10.3389/fncir.2023.1093066openalex-snapshot

Whole-brain mapping of long-range inputs to the VIP-expressing inhibitory neurons in the primary motor cortex

inferred← citeshttps://doi.org/10.3389/fnins.2021.643384openalex-snapshot

Stimulation in the Rat Anterior Insula and Anterior Cingulate During an Effortful Weightlifting Task

inferred← citeshttps://doi.org/10.3389/fnmol.2019.00303openalex-snapshot

Targeting Reciprocally Connected Brain Regions Through CAV-2 Mediated Interventions

inferred← citeshttps://doi.org/10.3389/fnmol.2020.00121openalex-snapshot

Targeting Catecholaminergic Systems in Transgenic Rats With a CAV-2 Vector Harboring a Cre-Dependent DREADD Cassette

inferred← citeshttps://doi.org/10.64898/2026.07.31.741703openalex-snapshot

Mapping excitatory synaptic plasticity evoked by single-dose psilocybin in mice

inferred← citeshttps://doi.org/10.70675/03a75158z9d38z4e81zb3aczea487daa9f14openalex-snapshot

Striatum, Dopamine and Automatism in Cocaine Addiction and Relapse : Pharmacological and Behavioral Investigation

inferred← citeshttps://doi.org/10.70675/2b7d6591z8d6ez4ea4zbaefz320275b736b1openalex-snapshot

Neurophysiological and computational bases of goal-directed behavior

inferred← citeshttps://doi.org/10.70675/6619b466z54bfz41e3z8a90zf0967825d579openalex-snapshot

Etude de l'implication du système dopaminergique nigrostrié dans les comportements motivés et l'alcoolodépendance

inferred← citeshttps://doi.org/10.70675/6b1c8a4azddaaz4316z805ez00f4a7232467openalex-snapshot

Flexibilité du comportement chez le primate : étude des dynamiques et connectivités fonctionnelles frontales

inferred← citeshttps://doi.org/10.70675/857ca5a2ze261z4e9bzb88dz744191d18105openalex-snapshot

Contribution of the rat insular cortex to stimulus-guided action

inferred← citeshttps://doi.org/10.70675/a7b03d10z7e3cz45a1z817bza6c6344893afopenalex-snapshot

Dynamiques dopaminergiques dans la prise de décision : rôle dans la variabilité et l’exploration

inferred← citeshttps://doi.org/10.70675/a8f4e479z2341z4f88zaf5bz91e7451d469dopenalex-snapshot

Functional characterization of Amygdala projections to motor related cortices during adaptive action-selection

inferred← citeshttps://doi.org/10.70675/d4f665b9z3943z4c88z9b4bzbf11cd7cf8d1openalex-snapshot

Cortex préfrontal et flexibilité comportementale : implication de la noradrénaline

inferred← citeshttps://doi.org/10.70675/deeb43a5z6accz4998z8619z6a33d6f4be8eopenalex-snapshot

Neuronal basis of decision-making under opposed valence affective states

inferred← citeshttps://doi.org/10.7554/elife.32517openalex-snapshot

Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat

inferred← citeshttps://doi.org/10.7554/elife.37357openalex-snapshot

Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

inferred← citeshttps://doi.org/10.7554/elife.41152openalex-snapshot

Sucrose intensity coding and decision-making in rat gustatory cortices

inferred← citeshttps://doi.org/10.7554/elife.46187openalex-snapshot

A thalamocortical circuit for updating action-outcome associations

inferred← citeshttps://doi.org/10.7554/elife.51333openalex-snapshot

mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking

inferred← citeshttps://doi.org/10.7554/elife.80926openalex-snapshot

Amygdala-cortical collaboration in reward learning and decision making

inferred← citeshttps://doi.org/10.7554/elife.81623openalex-snapshot

Inhibition of noradrenergic signalling in rodent orbitofrontal cortex impairs the updating of goal-directed actions

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