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A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis

https://doi.org/10.1093/cvr/cvv218
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/clc.4960280510openalex-snapshot
Comparison of high-density and low-density lipoprotein cholesterol subclasses and sizes in asian indian women with caucasian women from the framingham offspring study
inferredcites →https://doi.org/10.1006/jcis.1996.0217openalex-snapshot
Methods of Digital Video Microscopy for Colloidal Studies
inferredcites →https://doi.org/10.1016/j.ajpath.2011.12.002openalex-snapshot
Co-Regulation of Transcellular and Paracellular Leak Across Microvascular Endothelium by Dynamin and Rac
inferredcites →https://doi.org/10.1016/j.cmet.2009.06.003openalex-snapshot
Genetic Evidence Supporting a Critical Role of Endothelial Caveolin-1 during the Progression of Atherosclerosis
inferredcites →https://doi.org/10.1016/j.devcel.2014.04.031openalex-snapshot
Actin Cytoskeleton Reorganization by Syk Regulates Fcγ Receptor Responsiveness by Increasing Its Lateral Mobility and Clustering
inferredcites →https://doi.org/10.1016/s0002-9440(10)63341-xopenalex-snapshot
Dual Role for Scavenger Receptor Class B, Type I on Bone Marrow-Derived Cells in Atherosclerotic Lesion Development
inferredcites →https://doi.org/10.1016/s0009-8981(99)00101-1openalex-snapshot
Scavenger receptors and oxidized low density lipoproteins
inferredcites →https://doi.org/10.1016/s0022-2275(20)32566-9openalex-snapshot
Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL
inferredcites →https://doi.org/10.1016/s1357-2725(03)00173-0openalex-snapshot
The role of scavenger receptor class B type I (SR-BI) in lipid trafficking
inferredcites →https://doi.org/10.1038/aps.2010.87openalex-snapshot
Caveolae and caveolin-1 mediate endocytosis and transcytosis of oxidized low density lipoprotein in endothelial cells
inferredcites →https://doi.org/10.1038/nature12684openalex-snapshot
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36
inferredcites →https://doi.org/10.1073/pnas.95.8.4619openalex-snapshot
Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol
inferredcites →https://doi.org/10.1073/pnas.96.16.9322openalex-snapshot
Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology
inferredcites →https://doi.org/10.1074/jbc.272.41.25968openalex-snapshot
Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway
inferredcites →https://doi.org/10.1074/jbc.c100613200openalex-snapshot
Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo
inferredcites →https://doi.org/10.1074/jbc.m205948200openalex-snapshot
Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice
inferredcites →https://doi.org/10.1074/jbc.m510261200openalex-snapshot
SR-BI-mediated High Density Lipoprotein (HDL) Endocytosis Leads to HDL Resecretion Facilitating Cholesterol Efflux
inferredcites →https://doi.org/10.1074/jbc.m708098200openalex-snapshot
The Proprotein Convertase PCSK9 Induces the Degradation of Low Density Lipoprotein Receptor (LDLR) and Its Closest Family Members VLDLR and ApoER2
inferredcites →https://doi.org/10.1083/jcb.141.1.101openalex-snapshot
Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium
inferredcites →https://doi.org/10.1083/jcb.201004104openalex-snapshot
Metadata matters: access to image data in the real world
inferredcites →https://doi.org/10.1083/jcb.96.6.1677openalex-snapshot
Visualization of the binding, endocytosis, and transcytosis of low-density lipoprotein in the arterial endothelium in situ.
inferredcites →https://doi.org/10.1091/mbc.e14-08-1307openalex-snapshot
Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells
inferredcites →https://doi.org/10.1096/fasebj.26.1_supplement.862.1openalex-snapshot
Co‐regulation of Transcellular and Paracellular Leak Across Microvascular Endothelium By Dynamin and Rac
inferredcites →https://doi.org/10.1097/mol.0b013e32832afd63openalex-snapshot
Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by lipoproteins
inferredcites →https://doi.org/10.1111/bph.12616openalex-snapshot
C ‐reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cells
inferredcites →https://doi.org/10.1111/j.1365-2818.2006.01706.xopenalex-snapshot
A guided tour into subcellular colocalization analysis in light microscopy
inferredcites →https://doi.org/10.1111/tra.12119openalex-snapshot
Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis
inferredcites →https://doi.org/10.1139/o03-071openalex-snapshot
Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease
inferredcites →https://doi.org/10.1152/ajpcell.00185.2008openalex-snapshot
Role of caveolin-1 in the regulation of lipoprotein metabolism
inferredcites →https://doi.org/10.1152/ajpheart.00445.2010openalex-snapshot
The role of mitosis in LDL transport through cultured endothelial cell monolayers
inferredcites →https://doi.org/10.1152/ajpheart.01188.2006openalex-snapshot
In vitro study of LDL transport under pressurized (convective) conditions
inferredcites →https://doi.org/10.1152/ajpheart.1998.275.4.h1138openalex-snapshot
Neutrophil-dependent augmentation of PAF-induced vasoconstriction and albumin flux in coronary arterioles
inferredcites →https://doi.org/10.1161/01.atv.0000083343.19940.a0openalex-snapshot
Scavenger Receptor Class B Type I–Mediated Protection Against Atherosclerosis in LDL Receptor–Negative Mice Involves Its Expression in Bone Marrow–Derived Cells
inferredcites →https://doi.org/10.1161/01.atv.0000101182.89118.e5openalex-snapshot
Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis
inferredcites →https://doi.org/10.1161/01.atv.10.5.703openalex-snapshot
Role of dying endothelial cells in transendothelial macromolecular transport.
inferredcites →https://doi.org/10.1161/01.atv.14.8.1258openalex-snapshot
Response to HMG CoA reductase inhibitors in heterozygous familial hypercholesterolemia due to the 10-kb deletion ("French Canadian mutation") of the LDL receptor gene.
inferredcites →https://doi.org/10.1161/01.atv.15.5.551openalex-snapshot
The Response-to-Retention Hypothesis of Early Atherogenesis
inferredcites →https://doi.org/10.1161/01.atv.17.11.2341openalex-snapshot
CLA-1 Is an 85-kD Plasma Membrane Glycoprotein That Acts as a High-Affinity Receptor for Both Native (HDL, LDL, and VLDL) and Modified (OxLDL and AcLDL) Lipoproteins
inferredcites →https://doi.org/10.1161/01.atv.20.4.1068openalex-snapshot
Increased LDL Cholesterol and Atherosclerosis in LDL Receptor–Deficient Mice With Attenuated Expression of Scavenger Receptor B1
inferredcites →https://doi.org/10.1161/01.atv.20.8.1860openalex-snapshot
Hepatic and Extrahepatic Scavenger Receptors
inferredcites →https://doi.org/10.1161/01.cir.0000093189.97429.9dopenalex-snapshot
Inactivation of Macrophage Scavenger Receptor Class B Type I Promotes Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice
inferredcites →https://doi.org/10.1161/atvbaha.108.179564openalex-snapshot
The LDL Receptor
inferredcites →https://doi.org/10.1161/circresaha.108.190587openalex-snapshot
High-Density Lipoprotein Transport Through Aortic Endothelial Cells Involves Scavenger Receptor BI and ATP-Binding Cassette Transporter G1
inferredcites →https://doi.org/10.1177/33.8.4020099openalex-snapshot
Application of Nile red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: comparison with oil red O.
inferredcites →https://doi.org/10.1194/jlr.cx00001-jlr200openalex-snapshot
Errata. PCSK9 function and physiology
inferredcites →https://doi.org/10.1194/jlr.e800008-jlr200openalex-snapshot
PCSK9 function and physiology
inferredcites →https://doi.org/10.1194/jlr.m011981openalex-snapshot
Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells
inferredcites →https://doi.org/10.1194/jlr.m700355-jlr200openalex-snapshot
Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo
inferredcites →https://doi.org/10.1371/journal.pone.0000505openalex-snapshot
Quantifying Exocytosis by Combination of Membrane Capacitance Measurements and Total Internal Reflection Fluorescence Microscopy in Chromaffin Cells
inferredcites →https://doi.org/10.2353/ajpath.2010.091287openalex-snapshot
Endothelial-Specific Overexpression of Caveolin-1 Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Nanotherapy for Early Dementia: Targeting Senile Endothelium
inferred← citeshttps://doi.org/10.2139/ssrn.3041744openalex-extracted
Nanotherapy for Alzheimer's Disease and Vascular Dementia: Targeting Senile Endothelium
inferred← citeshttps://doi.org/10.1002/wsbm.1546openalex-snapshot
Modeling cholesterol metabolism and atherosclerosis
inferred← citeshttps://doi.org/10.1007/978-1-0716-2051-9_7openalex-snapshot
Quantifying Endothelial Transcytosis with Total Internal Reflection Fluorescence Microscopy (TIRF)
inferred← citeshttps://doi.org/10.1007/978-3-031-09741-6_1openalex-snapshot
Peripheral Arterial Atherogenesis
inferred← citeshttps://doi.org/10.1007/978-3-031-41192-2_7openalex-snapshot
Disorders of Cholesterol Trafficking and the Formation of Cholesterol Crystals in Atherosclerotic Plaque
inferred← citeshttps://doi.org/10.1007/s00018-018-2982-xopenalex-snapshot
Intracellular transport and regulation of transcytosis across the blood–brain barrier
inferred← citeshttps://doi.org/10.1007/s10517-024-05988-2openalex-snapshot
The Influence of Adiponectin on Transport of Low-Density Lipoproteins through Human Endothelial Cell Monolayer In Vitro
inferred← citeshttps://doi.org/10.1007/s11883-020-00903-2openalex-snapshot
Novel Functions of Endothelial Scavenger Receptor Class B Type I
inferred← citeshttps://doi.org/10.1007/s11883-023-01118-xopenalex-snapshot
LDL Transcytosis by the Arterial Endothelium—Atherosclerosis by a Thousand Cuts?
inferred← citeshttps://doi.org/10.1007/s11886-016-0745-6openalex-snapshot
Triglyceride-Rich Lipoproteins and Remnants: Targets for Therapy?
inferred← citeshttps://doi.org/10.1016/b978-0-12-812513-7.00008-2openalex-snapshot
Role of SR-BI in HDL Metabolism
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2018.06.881openalex-snapshot
Endocytosis of lipoproteins
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2018.07.014openalex-snapshot
Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2018.09.037openalex-snapshot
CTRP5 promotes transcytosis and oxidative modification of low-density lipoprotein and the development of atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2020.09.020openalex-snapshot
Transendothelial transport of lipoproteins
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2021.08.025openalex-snapshot
Endothelial cells exposed to atheroprotective flow secrete follistatin-like 1 protein which reduces transcytosis and inflammation
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2023.04.002openalex-snapshot
Regulation of low-density lipoprotein transport through endothelial cells by caveolae
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2023.117278openalex-snapshot
Sex differences in vascular endothelial cells
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.117545openalex-snapshot
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
inferred← citeshttps://doi.org/10.1016/j.bbagen.2019.01.005openalex-snapshot
Involvement of caveolin-1 and CD36 in native LDL endocytosis by endothelial cells
inferred← citeshttps://doi.org/10.1016/j.bbalip.2016.06.001openalex-snapshot
Low-density lipoprotein upregulate SR-BI through Sp1 Ser702 phosphorylation in hepatic cells
inferred← citeshttps://doi.org/10.1016/j.bbalip.2020.158791openalex-snapshot
Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions
inferred← citeshttps://doi.org/10.1016/j.cellsig.2022.110399openalex-snapshot
Deciphering the relationship between caveolae-mediated intracellular transport and signalling events
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111252openalex-snapshot
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway
inferred← citeshttps://doi.org/10.1016/j.cis.2017.12.002openalex-snapshot
Nanotherapy for Alzheimer's disease and vascular dementia: Targeting senile endothelium
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115011openalex-snapshot
Benzo[a]pyrene and a high-fat diet induce aortic injury and promote low-density lipoprotein accumulation in the endothelium
inferred← citeshttps://doi.org/10.1016/j.ejcb.2025.151520openalex-snapshot
Human diamine oxidase undergoes transcytosis and colocalizes with the plasma membrane monoamine transporter indicating intracellular histamine degradation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.123836openalex-snapshot
Scavenger Receptor a Mediates Glycated LDL Transcytosis Across Endothelial Cells to Promote Atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.ijcrp.2026.200650openalex-snapshot
Early atherogenesis: In search of etiology
inferred← citeshttps://doi.org/10.1016/j.jacbts.2026.101624openalex-snapshot
Endothelial Cells at the Crossroad of Atherosclerosis and Metabolic Dysfunction–Associated Steatotic Liver Disease
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100045openalex-snapshot
Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions
inferred← citeshttps://doi.org/10.1016/j.jlr.2023.100475openalex-snapshot
Apolipoprotein C3: form begets function
inferred← citeshttps://doi.org/10.1016/j.jlr.2024.100530openalex-snapshot
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1
inferred← citeshttps://doi.org/10.1016/j.jlr.2024.100665openalex-snapshot
The two major splice variants of scavenger receptor BI differ by their interactions with lipoproteins and cellular localization in endothelial cells
inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100893openalex-snapshot
LDL transcytosis passes through the trans-Golgi network and requires Rab10
inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100894openalex-snapshot
Endothelial SR-B1 is dispensable for thermogenesis but promotes selective cholesterol uptake in brown adipose tissue
inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101154openalex-snapshot
A TRAK2–KIF5B Complex Mediates Microtubule-Based LDL Vesicle Transport During Endothelial Transcytosis
inferred← citeshttps://doi.org/10.1016/j.vph.2025.107549openalex-snapshot
Transcellular permeability of arterial endothelium to plasma LDL, an underexplored target in treating atherosclerosis: Novel insights and potential treatment strategies
inferred← citeshttps://doi.org/10.1021/jacs.4c00691openalex-snapshot
Engineering Biomimetic Protein Camouflage for Delivering Peptide/siRNA Nanocomplexes
inferred← citeshttps://doi.org/10.1038/cddis.2016.431openalex-snapshot
Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis
inferred← citeshttps://doi.org/10.1038/ncomms13516openalex-snapshot
Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells
inferred← citeshttps://doi.org/10.1038/s41467-017-01186-zopenalex-snapshot
Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis
inferred← citeshttps://doi.org/10.1038/s41467-023-38259-1openalex-snapshot
Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1
inferred← citeshttps://doi.org/10.1038/s41467-025-57404-6openalex-snapshot
E3 ubiquitin ligase RNF128 promotes Lys63-linked polyubiquitination on SRB1 in macrophages and aggravates atherosclerosis
inferred← citeshttps://doi.org/10.1038/s41467-025-68193-3openalex-snapshot
Non-remnant triglyceride-rich lipoproteins due to lipoprotein lipase deficiency increase atherosclerosis in mice
inferred← citeshttps://doi.org/10.1038/s41569-024-01111-0openalex-snapshot
Apolipoprotein B-containing lipoproteins in atherogenesis
inferred← citeshttps://doi.org/10.1038/s41586-019-1140-4openalex-snapshot
SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis
inferred← citeshttps://doi.org/10.1038/s42255-019-0072-5openalex-snapshot
The Janus-faced role of SR-BI in atherosclerosis
inferred← citeshttps://doi.org/10.1038/s44161-023-00266-2openalex-snapshot
Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice
inferred← citeshttps://doi.org/10.1039/d4nh00178hopenalex-snapshot
Protein corona potentiates the recovery of nanoparticle-induced disrupted tight junctions in endothelial cells
inferred← citeshttps://doi.org/10.1042/bst20200991openalex-snapshot
Trans-endothelial trafficking of metabolic substrates and its importance in cardio-metabolic disease
inferred← citeshttps://doi.org/10.1051/medsci/2019123openalex-snapshot
SR-B1
inferred← citeshttps://doi.org/10.1073/pnas.2509315122openalex-snapshot
Lipid raft proteomics identify endothelial myosin-9 (MYH9) as a regulator of low-density lipoprotein transcytosis and atherosclerosis
inferred← citeshttps://doi.org/10.1074/jbc.ra120.015680openalex-snapshot
BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells
inferred← citeshttps://doi.org/10.1093/cvr/cvad183openalex-snapshot
Sphingosine-1-phosphate receptor 3 regulates the transendothelial transport of high-density lipoproteins and low-density lipoproteins in opposite ways
inferred← citeshttps://doi.org/10.1093/cvr/cvz338openalex-snapshot
Lipoprotein receptor signalling in atherosclerosis
inferred← citeshttps://doi.org/10.1093/eurheartj/ehz962openalex-snapshot
Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel
inferred← citeshttps://doi.org/10.1096/fasebj.31.1_supplement.883.12openalex-snapshot
Investigating the Role of the Vascular Endothelium in Insulin Delivery
inferred← citeshttps://doi.org/10.1097/fjc.0000000000001320openalex-snapshot
The Critical Effect of Bile Acids in Atherosclerosis
inferred← citeshttps://doi.org/10.1097/md.0000000000027909openalex-snapshot
Efficacy and safety of Chinese herbal for carotid atherosclerosis
inferred← citeshttps://doi.org/10.1097/mol.0000000000000330openalex-snapshot
The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis: a triumph of simplicity
inferred← citeshttps://doi.org/10.1097/mol.0000000000000701openalex-snapshot
Transport of LDLs into the arterial wall: impact in atherosclerosis
inferred← citeshttps://doi.org/10.1097/mol.0000000000000843openalex-snapshot
Early atherogenesis: new insights from new approaches
inferred← citeshttps://doi.org/10.1097/mol.0000000000000959openalex-snapshot
Distinct roles of size-defined HDL subpopulations in cardiovascular disease
inferred← citeshttps://doi.org/10.1097/mol.0000000000000973openalex-snapshot
Inflammation in atherosclerosis: a Big Idea that has underperformed so far
inferred← citeshttps://doi.org/10.1097/xce.0000000000000172openalex-snapshot
Atherosclerosis: integration of its pathogenesis as a self-perpetuating propagating inflammation: a review
inferred← citeshttps://doi.org/10.1098/rstb.2016.0480openalex-snapshot
Functional role of extracellular vesicles and lipoproteins in the tumour microenvironment
inferred← citeshttps://doi.org/10.1101/2020.04.23.058263openalex-snapshot
Sphingosine-1-phosphate receptors 1 and 3 regulate the expression of scavenger receptor B1 in human aortic endothelial cells
inferred← citeshttps://doi.org/10.1101/2022.08.08.503162openalex-snapshot
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding scavenger receptor B1
inferred← citeshttps://doi.org/10.1111/bph.15272openalex-snapshot
LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims?
inferred← citeshttps://doi.org/10.1111/ejn.16586openalex-snapshot
Gene expression patterns of the LDL receptor and its inhibitor Pcsk9 in the adult zebrafish brain suggest a possible role in neurogenesis
inferred← citeshttps://doi.org/10.1111/tra.12533openalex-snapshot
Transcellular vesicular transport in epithelial and endothelial cells: Challenges and opportunities
inferred← citeshttps://doi.org/10.1115/1.4072608openalex-snapshot
Do Endothelial Cells Have “Comfort Zones” for a Range of Hemodynamic Stresses That Lead to Different Triggers of Atherosclerosis at Different Arterial Sites?
inferred← citeshttps://doi.org/10.1124/pharmrev.120.000096openalex-snapshot
Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies
inferred← citeshttps://doi.org/10.1126/scitranslmed.aaw1868openalex-snapshot
Long noncoding RNA SNHG12 integrates a DNA-PK–mediated DNA damage response and vascular senescence
inferred← citeshttps://doi.org/10.1152/ajplung.00127.2018openalex-snapshot
CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery
inferred← citeshttps://doi.org/10.1152/ajplung.00157.2015openalex-snapshot
Thrombin stimulates albumin transcytosis in lung microvascular endothelial cells via activation of acid sphingomyelinase
inferred← citeshttps://doi.org/10.1152/physiol.00010.2016openalex-snapshot
Endothelial Transcytosis of Insulin: Does It Contribute to Insulin Resistance?
inferred← citeshttps://doi.org/10.1155/2022/2253478openalex-snapshot
Atherogenesis, Transcytosis, and the Transmural Cholesterol Flux: A Critical Review
inferred← citeshttps://doi.org/10.1159/000525259openalex-snapshot
Apolipoprotein A-I Inhibits Transendothelial Transport of Apolipoprotein B-Carrying Lipoproteins and Enhances Its Associated High-Density Lipoprotein Formation
inferred← citeshttps://doi.org/10.1161/atvbaha.115.306798openalex-snapshot
Catch and Release
inferred← citeshttps://doi.org/10.1161/atvbaha.117.309284openalex-snapshot
VEGF-A Regulates Cellular Localization of SR-BI as Well as Transendothelial Transport of HDL but Not LDL
inferred← citeshttps://doi.org/10.1161/atvbaha.118.310792openalex-snapshot
Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein–Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1)
inferred← citeshttps://doi.org/10.1161/atvbaha.118.311620openalex-snapshot
Estrogen Reduces LDL (Low-Density Lipoprotein) Transcytosis
inferred← citeshttps://doi.org/10.1161/atvbaha.120.314557openalex-snapshot
Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2–SR-BI Axis
inferred← citeshttps://doi.org/10.1161/atvbaha.120.315421openalex-snapshot
Role of LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1) as a Cardiovascular Risk Predictor
inferred← citeshttps://doi.org/10.1161/atvbaha.121.316725openalex-snapshot
Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein
inferred← citeshttps://doi.org/10.1161/atvbaha.123.320163openalex-snapshot
Unexpected Antiatherogenic Effect: Myeloid-Derived Growth Factor Inhibits LDL Transcytosis
inferred← citeshttps://doi.org/10.1161/atvbaha.124.320940openalex-snapshot
IL-1β Induces LDL Transcytosis by a Novel Pathway Involving LDLR and Rab27a
inferred← citeshttps://doi.org/10.1161/atvbaha.124.321549openalex-snapshot
Transcytosis of LDL Across Arterial Endothelium: Mechanisms and Therapeutic Targets
inferred← citeshttps://doi.org/10.1161/atvbaha.125.318266openalex-snapshot
ABCA1-Mediated Structural Diversity of HDL Subspecies and Their Proposed Roles in Cardioprotection
inferred← citeshttps://doi.org/10.1161/atvbaha.125.321546openalex-snapshot
Endocytosis, Transcytosis, and Retroendocytosis of HDL: Mechanisms, Pathophysiology, and Options for Clinical Exploitation
inferred← citeshttps://doi.org/10.1161/atvbaha.125.323112openalex-snapshot
Tricuspid Aortic Valve Regurgitation Associates With Ascending Aortic Aneurysm Through Endothelial Activation and Lipoprotein Infiltration
inferred← citeshttps://doi.org/10.1161/atvbaha.125.323501openalex-snapshot
Endothelial Cell Regulation of Lipid Uptake During Feeding and Fasting
inferred← citeshttps://doi.org/10.1161/circgenetics.116.001402openalex-snapshot
SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)
inferred← citeshttps://doi.org/10.1161/circresaha.119.316539openalex-snapshot
Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation
inferred← citeshttps://doi.org/10.1161/circresaha.120.318003openalex-snapshot
Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism
inferred← citeshttps://doi.org/10.1161/circresaha.123.323100openalex-snapshot
Imbalance of APOB Lipoproteins and Large HDL in Type 1 Diabetes Drives Atherosclerosis
inferred← citeshttps://doi.org/10.1161/circresaha.125.327267openalex-snapshot
Triglyceride-Rich Lipoprotein Metabolism and Cardiovascular Risk in Diabetes: Bedside to Bench to Bedside
inferred← citeshttps://doi.org/10.1161/circulationaha.118.038571openalex-snapshot
Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation
inferred← citeshttps://doi.org/10.1172/jci145800openalex-snapshot
Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation
inferred← citeshttps://doi.org/10.1172/jci148556openalex-snapshot
Targeting the vasculature in cardiometabolic disease
inferred← citeshttps://doi.org/10.1172/jci190513openalex-snapshot
The N-terminus of apolipoprotein B mediates the interaction of atherogenic lipoproteins with endothelial cells
inferred← citeshttps://doi.org/10.1186/s10020-026-01484-7openalex-snapshot
IL-6 triggers lysosomal degradation of LDL-R and enhances LDL-C uptake in vascular endothelial cells via macropinocytosis
inferred← citeshttps://doi.org/10.1186/s12944-017-0488-4openalex-snapshot
Genetic determinants of inherited susceptibility to hypercholesterolemia – a comprehensive literature review
inferred← citeshttps://doi.org/10.1186/s12974-025-03466-8openalex-snapshot
Caveolin-1 negatively regulates the calcitonin receptor-like receptor and neuroinflammation in a female mouse model of migraine
inferred← citeshttps://doi.org/10.1186/s13019-025-03655-9openalex-snapshot
Recent insights into the pathophysiology and implications for surgery in atherosclerosis
inferred← citeshttps://doi.org/10.1186/s13024-020-00418-zopenalex-snapshot
An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
inferred← citeshttps://doi.org/10.1186/s40816-025-00404-2openalex-snapshot
The cardiometabolic benefits of curcumin: a focus on endothelial dysfunction and arterial stiffness in metabolic syndrome
inferred← citeshttps://doi.org/10.1194/jlr.m083311openalex-snapshot
Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma
inferred← citeshttps://doi.org/10.1194/jlr.r083121openalex-snapshot
Thematic Review Series: Lipid Transfer Proteins Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function
inferred← citeshttps://doi.org/10.1210/endocr/bqaa029openalex-snapshot
The Endothelial Barrier Is not Rate-limiting to Insulin Action in the Myocardium of Male Mice
inferred← citeshttps://doi.org/10.1242/jcs.264792openalex-snapshot
MERTK coordinates efferocytosis by regulating integrin localization and activation
inferred← citeshttps://doi.org/10.1371/journal.pone.0318118openalex-snapshot
Scavenger receptor class B type I knockout mice develop extensive diet-induced coronary artery atherosclerosis in an age-dependent manner
inferred← citeshttps://doi.org/10.1371/journal.pone.0339318openalex-snapshot
Fluid shear stress-dependent modulation of the basal endothelial glycocalyx
inferred← citeshttps://doi.org/10.15252/embj.2020106163openalex-snapshot
Transcytosis in the development and morphogenesis of epithelial tissues
inferred← citeshttps://doi.org/10.15761/gmc.1000111openalex-snapshot
Treating early dementia: Drug targeting and circumventing the blood-brain barrier
inferred← citeshttps://doi.org/10.17816/maj321958openalex-snapshot
The concept of endothelial transcytosis as a theoretical prerequisite for the development of prevention and treatment of atherosclerosis
inferred← citeshttps://doi.org/10.18585/inabj.v10i2.479openalex-snapshot
Advanced in Molecular Mechanisms of Atherosclerosis: From Lipids to Inflammation
inferred← citeshttps://doi.org/10.18632/oncotarget.20867openalex-snapshot
Meta-analysis of the association between SCARB1 polymorphism and fasting blood lipid levels
inferred← citeshttps://doi.org/10.20944/preprints201808.0204.v1openalex-snapshot
Targeted Nanotherapy for Cognitive Impairment: Blocking Amyloid-β-Induced Membrane Damage in Brain Tissue
inferred← citeshttps://doi.org/10.21037/cdt.2020.01.13openalex-snapshot
Carotid plaque imaging profiling in subjects with risk factors (diabetes and hypertension)
inferred← citeshttps://doi.org/10.21203/rs.3.rs-228632/v1openalex-snapshot
Comprehensive plasma lipidomic profiles reveal a lipid-based signature panel as a diagnostic and predictive biomarker for cerebral aneurysms
inferred← citeshttps://doi.org/10.2174/0929867325666180307114855openalex-snapshot
The Significance of Oxidized Low-Density Lipoprotein in Body Fluids as a Marker Related to Diseased Conditions
inferred← citeshttps://doi.org/10.2174/0929867325666180316121015openalex-snapshot
The Role of (Modified) Lipoproteins in Vascular Function: A Duet Between Monocytes and the Endothelium
inferred← citeshttps://doi.org/10.21926/obm.geriatr.1902057openalex-snapshot
Treating Dementia Early: Limiting Cellular Damage in Brain Tissue
inferred← citeshttps://doi.org/10.22541/au.158802228.84629505openalex-snapshot
LDL receptors, caveolae and cholesterol in endothelial cell dysfunction: oxLDL accomplices or victims?
inferred← citeshttps://doi.org/10.25177/jnms.2.1.rv.532openalex-snapshot
NANOTHERAPY TO DELAY COGNITIVE IMPAIRMENT: USING COLLOIDAL NANOCARRIERS TO BLOCK AMYLOID-β-INDUCED DAMAGE IN BRAIN CELL MEMBRANES
inferred← citeshttps://doi.org/10.31219/osf.io/3vysuopenalex-snapshot
Nanotherapy for Early Dementia: Targeting Senile Dementia
inferred← citeshttps://doi.org/10.31219/osf.io/3vysu_v1openalex-snapshot
Nanotherapy for Early Dementia: Targeting Senile Dementia
inferred← citeshttps://doi.org/10.31219/osf.io/9afh2openalex-snapshot
Nanotherapy for Alzheimer's disease and vascular dementia: Targeting senile endothelium
inferred← citeshttps://doi.org/10.3164/jcbn.24-30openalex-snapshot
Caveolae and caveolin-1 as targets of dietary polyphenols for protection against vascular endothelial dysfunction
inferred← citeshttps://doi.org/10.3389/fbioe.2022.836680openalex-snapshot
Haemodynamic Wall Shear Stress, Endothelial Permeability and Atherosclerosis—A Triad of Controversy
inferred← citeshttps://doi.org/10.3389/fcell.2024.1371769openalex-snapshot
Basal endothelial glycocalyx’s response to shear stress: a review of structure, function, and clinical implications
inferred← citeshttps://doi.org/10.3389/fcvm.2018.00130openalex-snapshot
Endothelial Transcytosis of Lipoproteins in Atherosclerosis
inferred← citeshttps://doi.org/10.3389/fcvm.2021.639946openalex-snapshot
Sex–Gender Disparities in Cardiovascular Diseases: The Effects of Estrogen on eNOS, Lipid Profile, and NFATs During Catecholamine Stress
inferred← citeshttps://doi.org/10.3389/fcvm.2022.1031293openalex-snapshot
Defective efferocytosis of vascular cells in heart disease
inferred← citeshttps://doi.org/10.3389/fcvm.2022.888390openalex-snapshot
The Endothelium as a Hub for Cellular Communication in Atherogenesis: Is There Directionality to the Message?
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1485801openalex-snapshot
Atherosclerosis: from lipid-lowering and anti-inflammatory therapies to targeting arterial retention of ApoB-containing lipoproteins
inferred← citeshttps://doi.org/10.3389/fphys.2017.00841openalex-snapshot
SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1
inferred← citeshttps://doi.org/10.3389/fphys.2022.1023397openalex-snapshot
Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium
inferred← citeshttps://doi.org/10.3390/biom12020158openalex-snapshot
Approaches to Visualising Endocytosis of LDL-Related Lipoproteins
inferred← citeshttps://doi.org/10.3390/biomedicines10123083openalex-snapshot
Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease
inferred← citeshttps://doi.org/10.3390/biomedicines9091214openalex-snapshot
Macrophages in Atherosclerosis, First or Second Row Players?
inferred← citeshttps://doi.org/10.3390/biomimetics3010004openalex-snapshot
Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.3390/cells10051041openalex-snapshot
The Endothelium Is Both a Target and a Barrier of HDL’s Protective Functions
inferred← citeshttps://doi.org/10.3390/cells11193044openalex-snapshot
Brain Endothelial Cells in Contrary to the Aortic Do Not Transport but Degrade Low-Density Lipoproteins via Both LDLR and ALK1
inferred← citeshttps://doi.org/10.3390/cells13100789openalex-snapshot
Hopping the Hurdle: Strategies to Enhance the Molecular Delivery to the Brain through the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.3390/ijms19113593openalex-snapshot
Transport of Apolipoprotein B-Containing Lipoproteins through Endothelial Cells Is Associated with Apolipoprotein E-Carrying HDL-Like Particle Formation
inferred← citeshttps://doi.org/10.3390/ijms22083850openalex-snapshot
Endothelial Dysfunction, Inflammation and Coronary Artery Disease: Potential Biomarkers and Promising Therapeutical Approaches
inferred← citeshttps://doi.org/10.3390/ijms222111545openalex-snapshot
Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology
inferred← citeshttps://doi.org/10.3390/ijms24108869openalex-snapshot
Caveolin-1 and Atherosclerosis: Regulation of LDLs Fate in Endothelial Cells
inferred← citeshttps://doi.org/10.3390/ijms25126415openalex-snapshot
Molecular Mechanisms Regulating Vascular Endothelial Permeability
inferred← citeshttps://doi.org/10.3390/jcm9103236openalex-snapshot
CoQ10 Deficient Endothelial Cell Culture Model for the Investigation of CoQ10 Blood–Brain Barrier Transport
inferred← citeshttps://doi.org/10.3390/life11101042openalex-snapshot
Ischemic Heart Disease and Rheumatoid Arthritis—Two Conditions, the Same Background
inferred← citeshttps://doi.org/10.3390/medsci5040029openalex-snapshot
Alzheimer’s Disease, Brain Injury, and C.N.S. Nanotherapy in Humans: Sonoporation Augmenting Drug Targeting
inferred← citeshttps://doi.org/10.3390/ph17070913openalex-snapshot
Lipoprotein Metabolism, Dyslipidemia, and Lipid-Lowering Therapy in Women: A Comprehensive Review
inferred← citeshttps://doi.org/10.37532/fmcp.2019.16(4).1221-1230openalex-snapshot
Shear stress regulates eNOS signaling in human umbilical vein endothelial cells via SRB1-PI3KAP1 pathway
inferred← citeshttps://doi.org/10.3889/oamjms.2021.7359openalex-snapshot
A Comparative Study between the Effect of Pandan Wangi Leaves Boiled Water with Medication Therapy on the Blood Pressure Changes of Hypertension Patients
inferred← citeshttps://doi.org/10.3892/mmr.2020.11383openalex-snapshot
Differential roles of Scavenger receptor class B type�I: A�protective molecule and a facilitator of atherosclerosis (Review)
inferred← citeshttps://doi.org/10.4321/repisalud.13414openalex-snapshot
Dynamics of LDL accumulation leading to atherosclerosis initiation
inferred← citeshttps://doi.org/10.47749/t/unicamp.2020.1128954openalex-snapshot
Modulação da aterogênese pela expressão da transidrogenase de nucleotídeo de nicotinamida (Nnt) e da proteína de transferência de colesterol esterificado (CETP) em macrófagos
inferred← citeshttps://doi.org/10.5528/wjtm.v8.i1.1openalex-snapshot
Inflammation and cardiovascular disease
inferred← citeshttps://doi.org/10.5551/jat.rv22017openalex-snapshot
In the Beginning, Lipoproteins Cross the Endothelial Barrier
inferred← citeshttps://doi.org/10.64898/2026.09.15.748866openalex-snapshot
GPR182 promotes atherosclerosis via facilitating arterial lipid deposition
inferred← citeshttps://doi.org/10.70675/5d269afcz42aez4bd5zaf6cz373fc60b5595openalex-snapshot
Restoration of autophagic flux in vascular endothelial cells to prevent atherosclerosis lesion development
inferred← citeshttps://doi.org/10.70675/759ed785ze142z4504za8abzd5cf222c1a59openalex-snapshot
Développement d'anticorps à domaine unique comme vecteurs ciblant des récepteurs impliqués dans la transcytose et traversant la barrière hémato-encéphalique pour l'adressage d'agents d'imagerie et thérapeutiques vers le cerveau
inferred← citeshttps://doi.org/10.70675/e8921266z6906z4421z8181z90a4f135bf9fopenalex-snapshot
Trafic intracellulaire de peptide-vecteurs ciblant le récepteur au LDL pour des stratégies de délivrance ciblée d'agents thérapeutiques ou d'imagerie à travers la barrière hémato-encéphalique
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