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PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/path.2697openalex-snapshot
Autophagy: cellular and molecular mechanisms
inferredcites →https://doi.org/10.1007/s00018-014-1762-5openalex-snapshot
Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling
inferredcites →https://doi.org/10.1007/s00395-014-0444-7openalex-snapshot
Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction
inferredcites →https://doi.org/10.1007/s11239-016-1364-1openalex-snapshot
PCSK9 inhibitors in the prevention of cardiovascular disease
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2011.07.098openalex-snapshot
Lack of association between plasma PCSK9 and LDL-apoB100 catabolism in patients with uncontrolled type 2 diabetes
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2013.04.034openalex-snapshot
Hypoxia enhances lipid uptake in macrophages: Role of the scavenger receptors Lox1, SRA, and CD36
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2015.01.012openalex-snapshot
PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2016.07.910openalex-snapshot
PCSK9 knock-out mice are protected from neointimal formation in response to perivascular carotid collar placement
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2016.08.007openalex-snapshot
PCSK9 and atherosclerosis: Beyond LDL-cholesterol lowering
inferredcites →https://doi.org/10.1016/j.bbadis.2014.05.010openalex-snapshot
The role of the autophagy in myocardial ischemia/reperfusion injury
inferredcites →https://doi.org/10.1016/j.bbrc.2013.09.131openalex-snapshot
Regulation of autophagy and apoptosis in response to angiotensin II in HL-1 cardiomyocytes
inferredcites →https://doi.org/10.1016/j.cardiores.2005.12.003openalex-snapshot
Studying ischemic preconditioning in isolated cardiomyocyte models
inferredcites →https://doi.org/10.1016/j.ijcard.2012.12.045openalex-snapshot
Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g
inferredcites →https://doi.org/10.1016/j.ijcard.2015.02.007openalex-snapshot
Oxidized LDL attenuates protective autophagy and induces apoptotic cell death of endothelial cells: Role of oxidative stress and LOX-1 receptor expression
inferredcites →https://doi.org/10.1016/s0735-1097(02)02966-2openalex-snapshot
Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction
inferredcites →https://doi.org/10.1038/aps.2014.151openalex-snapshot
The divergent roles of autophagy in ischemia and preconditioning
inferredcites →https://doi.org/10.1038/cddis.2011.130openalex-snapshot
Cardiomyocyte death: mechanisms and translational implications
inferredcites →https://doi.org/10.1039/c6mb00824kopenalex-snapshot
Soluble epoxide hydrolase inhibitors might prevent ischemic arrhythmias via microRNA-1 repression in primary neonatal mouse ventricular myocytes
inferredcites →https://doi.org/10.1042/cs20160061openalex-snapshot
Modulation of myocardial injury and collagen deposition following ischaemia–reperfusion by linagliptin and liraglutide, and both together
inferredcites →https://doi.org/10.1056/nejmoa1615664openalex-snapshot
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
inferredcites →https://doi.org/10.1074/jbc.m109.065102openalex-snapshot
PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation
inferredcites →https://doi.org/10.1074/jbc.m804209200openalex-snapshot
Protection of Cardiomyocytes from Ischemic/Hypoxic Cell Death via Drbp1 and pMe2GlyDH in Cardio-specific ARC Transgenic Mice
inferredcites →https://doi.org/10.1089/ars.2014.6054openalex-snapshot
Hemodynamic Shear Stress via ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta
inferredcites →https://doi.org/10.1089/ars.2016.6631openalex-snapshot
Cross-Talk Between PCSK9 and Damaged mtDNA in Vascular Smooth Muscle Cells: Role in Apoptosis
inferredcites →https://doi.org/10.1093/cvr/cvr073openalex-snapshot
The role of autophagy emerging in postinfarction cardiac remodelling
inferredcites →https://doi.org/10.1093/cvr/cvr358openalex-snapshot
Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges
inferredcites →https://doi.org/10.1093/cvr/cvv178openalex-snapshot
Cross-talk between LOX-1 and PCSK9 in vascular tissues
inferredcites →https://doi.org/10.1111/j.1600-065x.2012.01146.xopenalex-snapshot
PAMP s and DAMP s: signal 0s that spur autophagy and immunity
inferredcites →https://doi.org/10.1113/jp270953openalex-snapshot
Cardioprotection in ischaemia–reperfusion injury: novel mechanisms and clinical translation
inferredcites →https://doi.org/10.1152/ajpheart.01051.2008openalex-snapshot
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
inferredcites →https://doi.org/10.1161/01.res.0000130526.20854.faopenalex-snapshot
Inflammatory Cytokines and Postmyocardial Infarction Remodeling
inferredcites →https://doi.org/10.1161/01.res.0000261924.76669.36openalex-snapshot
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
inferredcites →https://doi.org/10.1161/circresaha.114.303788openalex-snapshot
Molecular Mechanisms of Autophagy in the Cardiovascular System
inferredcites →https://doi.org/10.1161/circulationaha.113.002416openalex-snapshot
Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy
inferredcites →https://doi.org/10.1161/circulationaha.115.017443openalex-snapshot
Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification
inferredcites →https://doi.org/10.1186/1471-2261-14-192openalex-snapshot
Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat
inferredcites →https://doi.org/10.11909/j.issn.1671-5411.2016.04.002openalex-snapshot
Positive correlation between plasma PCSK9 and tissue factors levels in patients with angiographically diagnosed coronary artery disease and diabetes mellitus.
inferredcites →https://doi.org/10.1371/journal.pone.0106294openalex-snapshot
Plasma PCSK9 Levels Are Elevated with Acute Myocardial Infarction in Two Independent Retrospective Angiographic Studies
inferredcites →https://doi.org/10.4161/auto.21036openalex-snapshot
Autophagy is impaired in cardiac ischemia-reperfusion injury
inferredcites →https://doi.org/10.4161/auto.27649openalex-snapshot
Autophagy is essential for cardiac morphogenesis during vertebrate development
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4112147openalex-extracted
Non-High-Density Lipoprotein Cholesterol and Risk of Cardiovascular Events: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1002/advs.202405955openalex-snapshot
Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy‐Mediated Eepd1 Degradation
inferred← citeshttps://doi.org/10.1002/ctm2.729openalex-snapshot
PCSK9 participates in oxidized‐low density lipoprotein‐induced myocardial injury through mitochondrial oxidative stress and Drp1‐mediated mitochondrial fission
inferred← citeshttps://doi.org/10.1002/ehf2.12533openalex-snapshot
Role of PCSK9 in the Course of Ejection Fraction Change after ST-Segment Elevation Myocardial Infarction: A Pilot Study
inferred← citeshttps://doi.org/10.1002/jcp.30025openalex-snapshot
Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall
inferred← citeshttps://doi.org/10.1007/978-3-031-36390-0_19openalex-snapshot
The Structure, Function, and Modification of Non-coding RNAs in Cardiovascular System
inferred← citeshttps://doi.org/10.1007/s00380-024-02473-8openalex-snapshot
Anti-inflammatory effects of proprotein convertase subtilisin/kexin 9 inhibitor therapy in the early phase of acute myocardial infarction
inferred← citeshttps://doi.org/10.1007/s00395-020-00824-wopenalex-snapshot
Autocrine effects of PCSK9 on cardiomyocytes
inferred← citeshttps://doi.org/10.1007/s00395-020-00825-9openalex-snapshot
Targeting myocardial ischaemic injury in the absence of reperfusion
inferred← citeshttps://doi.org/10.1007/s00395-020-00832-wopenalex-snapshot
PCSK9 regulates pyroptosis via mtDNA damage in chronic myocardial ischemia
inferred← citeshttps://doi.org/10.1007/s00395-025-01100-5openalex-snapshot
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes
inferred← citeshttps://doi.org/10.1007/s00395-026-01162-zopenalex-snapshot
Melatonin and mitochondrial protection in cardiac ischemia–reperfusion injury: mechanisms, evidence and translational perspectives
inferred← citeshttps://doi.org/10.1007/s10741-024-10409-7openalex-snapshot
The role of PCSK9 in heart failure and other cardiovascular diseases—mechanisms of action beyond its effect on LDL cholesterol
inferred← citeshttps://doi.org/10.1007/s10753-023-01865-8openalex-snapshot
Anti-PCSK9 Treatment Attenuates Liver Fibrosis via Inhibiting Hypoxia-Induced Autophagy in Hepatocytes
inferred← citeshttps://doi.org/10.1007/s11010-020-04029-6openalex-snapshot
MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
inferred← citeshttps://doi.org/10.1007/s11010-023-04856-3openalex-snapshot
Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
inferred← citeshttps://doi.org/10.1007/s11886-023-01918-2openalex-snapshot
Pleiotropy of PCSK9: Functions in Extrahepatic Tissues
inferred← citeshttps://doi.org/10.1007/s12012-022-09771-5openalex-snapshot
PCSK9 Knockdown Can Improve Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy
inferred← citeshttps://doi.org/10.1007/s12013-023-01136-1openalex-snapshot
PCSK9 Inhibition Regulates Infarction-Induced Cardiac Myofibroblast Transdifferentiation via Notch1 Signaling
inferred← citeshttps://doi.org/10.1007/s13273-023-00352-3openalex-snapshot
PCSK9 regulates myocardial ischemia–reperfusion injury through parkin/pink1-mediated autophagy pathway
inferred← citeshttps://doi.org/10.1007/s40265-025-02221-wopenalex-snapshot
PCSK9 Inhibitors: A Potential Priority Choice for Lipid Management in Patients with Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.1007/s40292-024-00676-8openalex-snapshot
PCSK9 Inhibitors: Is the Time Ripe for the “Fast Track” Use Independently on the LDL-C Baseline Values in Acute Coronary Syndrome?
inferred← citeshttps://doi.org/10.1007/s43630-022-00221-3openalex-snapshot
Low-power infrared laser modulates mRNA levels from genes of base excision repair and genomic stabilization in heart tissue from an experimental model of acute lung injury
inferred← citeshttps://doi.org/10.1016/j.abb.2020.108717openalex-snapshot
PCSK9: Associated with cardiac diseases and their risk factors?
inferred← citeshttps://doi.org/10.1016/j.acvd.2019.06.003openalex-snapshot
Proprotein convertase subtilisin/kexin type 9 inhibitors: New insights into cardiovascular atherosclerotic pathophysiology with therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102629openalex-snapshot
Regulated cell death in acute myocardial infarction: Molecular mechanisms and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2019.07.002openalex-snapshot
Interaction between serum endotoxemia and proprotein convertase subtilisin/kexin 9 (PCSK9) in patients with atrial fibrillation: A post-hoc analysis from the ATHERO-AF cohort
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2023.06.971openalex-snapshot
Evidence of an anti-inflammatory effect of PCSK9 inhibitors within the human atherosclerotic plaque
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.151081openalex-snapshot
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy
inferred← citeshttps://doi.org/10.1016/j.bbrep.2023.101463openalex-snapshot
Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116563openalex-snapshot
PCSK9 inhibitor attenuates cardiac fibrosis in reperfusion injury rat by suppressing inflammatory response and TGF-β1/Smad3 pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.114106openalex-snapshot
PCSK9: A emerging participant in heart failure
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.114198openalex-snapshot
Effects of shear stress on vascular endothelial functions in atherosclerosis and potential therapeutic approaches
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177499openalex-snapshot
Evolocumab ameliorates myocardial fibrosis and improves metabolic syndrome–induced cardiac dysfunction in rats via inhibiting PCSK9/NLRP3 inflammasome and Caspase-1 / IL-1β pathways
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.02.047openalex-snapshot
AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2023.04.005openalex-snapshot
PCSK6 attenuates cardiac dysfunction in doxorubicin-induced cardiotoxicity by regulating autophagy
inferred← citeshttps://doi.org/10.1016/j.ijcha.2026.101918openalex-snapshot
Multi-biomarker approach for predicting cardiac magnetic resonance parameters at 30 days after ST-segment elevation myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110962openalex-snapshot
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107517openalex-snapshot
Proprotein convertase subtilisin/kexin type 9 inhibitor ameliorates cerebral ischemia in mice by inhibiting inflammation
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120560openalex-snapshot
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome
inferred← citeshttps://doi.org/10.1016/j.medmic.2021.100033openalex-snapshot
Heart-gut axis: Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) to prevent cardiovascular disease through gut microbiota
inferred← citeshttps://doi.org/10.1016/j.metabol.2024.156064openalex-snapshot
PCSK9 in metabolism and diseases
inferred← citeshttps://doi.org/10.1016/j.molmed.2022.09.004openalex-snapshot
Molecular basis and clinical implications of HIFs in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.mvr.2022.104371openalex-snapshot
PCSK9 inhibition protects against myocardial ischemia-reperfusion injury via suppressing autophagy
inferred← citeshttps://doi.org/10.1016/j.mvr.2025.104847openalex-snapshot
PCSK9 inhibitor improved cardiac function after acute myocardial infarction in rats
inferred← citeshttps://doi.org/10.1016/j.mvr.2026.104925openalex-snapshot
The possible role of PCSK9 inhibitors in cardiac syndrome X: Bridging microvascular dysfunction, endothelial pathobiology, and molecular pharmacotherapy
inferred← citeshttps://doi.org/10.1016/j.numecd.2022.06.020openalex-snapshot
Relationship between PCSK9 and endothelial function in patients with acute myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.numecd.2023.05.033openalex-snapshot
Efficacy and safety of PCSK9 inhibitors in patients with diabetes: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.nut.2020.110954openalex-snapshot
Hepatic cholesterol synthesis and lipoprotein levels impaired by dietary fructose and saturated fatty acids in mice: Insight on PCSK9 and CD36
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2025.108812openalex-snapshot
Therapeutic PCSK9 targeting: Inside versus outside the hepatocyte?
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2022.08.348openalex-snapshot
Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function
inferred← citeshttps://doi.org/10.1038/s41392-023-01652-9openalex-snapshot
Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41392-023-01690-3openalex-snapshot
Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside
inferred← citeshttps://doi.org/10.1038/s41598-022-22367-xopenalex-snapshot
Serum biomarkers, including nitric oxide metabolites (NOx), for prognosis of cardiovascular death and acute myocardial infarction in an ESSE-RF case–control cohort with 6.5-year follow up
inferred← citeshttps://doi.org/10.1038/s41598-023-33287-9openalex-snapshot
PCSK9, a novel immune and ferroptosis related gene in abdominal aortic aneurysm neck
inferred← citeshttps://doi.org/10.1038/s41598-023-50866-yopenalex-snapshot
1H-NMR metabolomics analysis identifies hypoxanthine as a novel metastasis-associated metabolite in breast cancer
inferred← citeshttps://doi.org/10.1038/s41598-025-03419-4openalex-snapshot
The function of PCSK9 in doxorubicin-induced cardiotoxicity and its underlying mechanism
inferred← citeshttps://doi.org/10.1038/s41598-025-93750-7openalex-snapshot
The correlation between proprotein convertase subtilisin/kexin type 9 and adiponectin in the progression from prediabetes to type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1055/s-0042-1758654openalex-snapshot
Drug–Drug Interaction between Antiplatelet Therapy and Lipid-Lowering Agents (Statins and PCSK9 Inhibitors)
inferred← citeshttps://doi.org/10.1080/1061186x.2022.2092622openalex-snapshot
Molecular and cellular biology of PCSK9: impact on glucose homeostasis
inferred← citeshttps://doi.org/10.1080/13813455.2020.1788605openalex-snapshot
Evolocumab, a PCSK9 inhibitor, protects human endothelial cells against H 2 O 2 -induced oxidative stress
inferred← citeshttps://doi.org/10.1080/14728222.2025.2482545openalex-snapshot
Targeting PCSK9 beyond the liver: evidence from experimental and clinical studies
inferred← citeshttps://doi.org/10.1089/scd.2020.0132openalex-snapshot
Exosomes Protect Against Acute Myocardial Infarction in Rats by Regulating the Renin-Angiotensin System
inferred← citeshttps://doi.org/10.1093/cvr/cvad041openalex-snapshot
Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function
inferred← citeshttps://doi.org/10.1093/cvr/cvz224openalex-snapshot
Autophagy promotes longevity—except in the presence of ‘leaky’ mitochondria
inferred← citeshttps://doi.org/10.1093/cvr/cvz313openalex-snapshot
PCSK9 and inflammation: role of shear stress, pro-inflammatory cytokines, and LOX-1
inferred← citeshttps://doi.org/10.1093/ejhf/xuag166openalex-snapshot
PCSK9 inhibition and cardiovascular outcomes by heart failure status: a pooled analysis of SPIRE-1 and SPIRE-2
inferred← citeshttps://doi.org/10.1093/eurheartj/ehab431openalex-snapshot
PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction
inferred← citeshttps://doi.org/10.1093/qjmed/hcag235openalex-snapshot
Association between PCSK9 inhibitor use and risk of incident heart failure in patients with dyslipidemia
inferred← citeshttps://doi.org/10.1096/fj.202300248ropenalex-snapshot
TWF1 induces autophagy and accelerates malignant phenotype in lung adenocarcinoma via inhibiting the cAMP signaling pathway
inferred← citeshttps://doi.org/10.1097/cd9.0000000000000149openalex-snapshot
Early PCSK9 Inhibitor Therapy Following Percutaneous Coronary Intervention (PERFECT): A Pilot Randomized Controlled Trial
inferred← citeshttps://doi.org/10.1111/apha.14272openalex-snapshot
The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism
inferred← citeshttps://doi.org/10.1111/cpr.70244openalex-snapshot
Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression
inferred← citeshttps://doi.org/10.1111/jcmm.14586openalex-snapshot
PCSK9 inhibitor improves cardiac function and reduces infarct size in rats with ischaemia/reperfusion injury: Benefits beyond lipid‐lowering effects
inferred← citeshttps://doi.org/10.1111/jcmm.14953openalex-snapshot
Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST‐segment elevation myocardial infarction
inferred← citeshttps://doi.org/10.1124/pharmrev.121.000348openalex-snapshot
Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning
inferred← citeshttps://doi.org/10.1139/bcb-2021-0540openalex-snapshot
The biological relevance of PCSK9: when less is better…
inferred← citeshttps://doi.org/10.1139/cjpp-2023-0223openalex-snapshot
Role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in diabetic complications
inferred← citeshttps://doi.org/10.1152/ajpregu.00124.2021openalex-snapshot
Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
inferred← citeshttps://doi.org/10.1155/2020/1348913openalex-snapshot
PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation
inferred← citeshttps://doi.org/10.1155/2022/4964262openalex-snapshot
Protective Mechanism of Proprotein Convertase Subtilisin-Like Kexin Type 9 Inhibitor on Rats with Middle Cerebral Artery Occlusion-Induced Cerebral Ischemic Infarction
inferred← citeshttps://doi.org/10.1155/2022/7685796openalex-snapshot
PCSK9 Modulates Macrophage Polarization-Mediated Ventricular Remodeling after Myocardial Infarction
inferred← citeshttps://doi.org/10.1161/atvbaha.124.320140openalex-snapshot
Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1161/circimaging.123.016482openalex-snapshot
Association of Circulating PCSK9 With Ischemia-Reperfusion Injury in Acute ST-Elevation Myocardial Infarction
inferred← citeshttps://doi.org/10.1161/circimaging.124.017210openalex-snapshot
Is PCSK9 the Key Player in the Ischemia-Reperfusion Match?
inferred← citeshttps://doi.org/10.1161/circresaha.124.325629openalex-snapshot
PCSK9 Regulates Cardiac Mitochondrial Cholesterol by Promoting TSPO Degradation
inferred← citeshttps://doi.org/10.1161/circulationaha.120.046290openalex-snapshot
PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36
inferred← citeshttps://doi.org/10.1186/s12872-025-05383-3openalex-snapshot
Proteome-wide Mendelian randomization identifies drug targets for atrial fibrillation/flutter
inferred← citeshttps://doi.org/10.1186/s12920-024-01826-6openalex-snapshot
Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9
inferred← citeshttps://doi.org/10.1186/s13098-023-01238-zopenalex-snapshot
Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.12677/acm.2023.1381742openalex-snapshot
Application of PCSK9 Inhibitors in Lipid Metabolism and Arteriosclerosis
inferred← citeshttps://doi.org/10.12677/acm.2025.153605openalex-snapshot
Research Progress of PCSK9 in Clinical Practice
inferred← citeshttps://doi.org/10.1371/journal.pgen.1009483openalex-snapshot
Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics
inferred← citeshttps://doi.org/10.1507/endocrj.ej23-0359openalex-snapshot
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy
inferred← citeshttps://doi.org/10.15829/1560-4071-2023-5201openalex-snapshot
Predictors of post-infarction left ventricular aneurysm
inferred← citeshttps://doi.org/10.18535/jmscr/v9i11.39openalex-snapshot
A study of correlation of PCSK9 enzyme levels in patients with coronary artery disease and diabetes mellitus
inferred← citeshttps://doi.org/10.20517/2574-1209.2020.71openalex-snapshot
The local effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) on the inflammatory atheroma: beyond LDL cholesterol lowering
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1407354/v1openalex-snapshot
Serum Nitric Oxide Metabolites (Nox) for Prognosis of Cardiovascular Death and Acute Myocardial Infarction in An ESSE-RF Case-Control Cohort with 6.5 Year Follow Up
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1407354/v2openalex-snapshot
Serum nitric oxide metabolites (NOx) for prognosis of cardiovascular death and acute myocardial infarction in an ESSE-RF case-control cohort with 6.5 year follow up
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1610254/v1openalex-snapshot
Knock down of PCSK9 can improve myocardial ischemia/reperfusion injury by inhibiting autophagy
inferred← citeshttps://doi.org/10.2174/0929867328666210714160343openalex-snapshot
The Role of PCSK9 in Infectious Diseases
inferred← citeshttps://doi.org/10.2174/0929867328666210804091003openalex-snapshot
PCSK9 Inhibition could be Effective for Acute Myocardial Infarction
inferred← citeshttps://doi.org/10.2174/0929867329666220727113129openalex-snapshot
Lipophagy: A Potential Therapeutic Target for Diabetic Nephropathy
inferred← citeshttps://doi.org/10.2217/bmm-2020-0585openalex-snapshot
Associations of Serially Measured Pcsk9, Ldlr and Mpo with Clinical Outcomes in Heart Failure
inferred← citeshttps://doi.org/10.31083/j.rcm2510374openalex-snapshot
Rationale for Early Administration of PCSK9 Inhibitors in Acute Coronary Syndrome
inferred← citeshttps://doi.org/10.3233/ch-242444openalex-snapshot
RETRACTED: PCSK9 inhibitor protects against myocardial ischemia-reperfusion injury via inhibiting LRP8/GPX4-mediated ferroptosis
inferred← citeshttps://doi.org/10.33696/cardiology.3.029openalex-snapshot
Should we Target Myostatin, PCSK9 or Their Combination in Ischemia/Reperfusion Injury?
inferred← citeshttps://doi.org/10.3389/fcvm.2021.760140openalex-snapshot
Gene Therapy for Cardiovascular Disease: Basic Research and Clinical Prospects
inferred← citeshttps://doi.org/10.3389/fcvm.2022.1009674openalex-snapshot
Impact of early PCSK9 inhibitor treatment on heart after percutaneous coronary intervention in patients with STEMI: Design and rationale of the PERFECT II trial
inferred← citeshttps://doi.org/10.3389/fcvm.2023.1148486openalex-snapshot
Effect of PCSK9 on atherosclerotic cardiovascular diseases and its mechanisms: Focus on immune regulation
inferred← citeshttps://doi.org/10.3389/fcvm.2023.1191303openalex-snapshot
Proteomics and Lipidomics to unveil the contribution of PCSK9 beyond cholesterol lowering: a narrative review
inferred← citeshttps://doi.org/10.3389/fcvm.2024.1463844openalex-snapshot
PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction
inferred← citeshttps://doi.org/10.3389/fcvm.2026.1744830openalex-snapshot
LDL receptor-independent mechanisms of proprotein convertase subtilisin/kexin type 9 in cardiovascular pathophysiology
inferred← citeshttps://doi.org/10.3389/fendo.2020.607144openalex-snapshot
Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts
inferred← citeshttps://doi.org/10.3389/fgene.2020.01020openalex-snapshot
PCSK9 Variants in Familial Hypercholesterolemia: A Comprehensive Synopsis
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1126823openalex-snapshot
Interactions between PCSK9 and NLRP3 inflammasome signaling in atherosclerosis
inferred← citeshttps://doi.org/10.3389/fphar.2024.1353848openalex-snapshot
Association between PCSK9 inhibitors and acute kidney injury: a pharmacovigilance study
inferred← citeshttps://doi.org/10.3389/fphar.2024.1413123openalex-snapshot
Proprotein convertase subtilisin/kexin type 9 deficiency in extrahepatic tissues: emerging considerations
inferred← citeshttps://doi.org/10.3389/fphys.2020.598649openalex-snapshot
Coming Back to Physiology: Extra Hepatic Functions of Proprotein Convertase Subtilisin/Kexin Type 9
inferred← citeshttps://doi.org/10.3389/fphys.2020.602497openalex-snapshot
PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation
inferred← citeshttps://doi.org/10.3389/fphys.2021.593862openalex-snapshot
Impact of PCSK9 on CTRP9-Induced Metabolic Effects in Adult Rat Cardiomyocytes
inferred← citeshttps://doi.org/10.3390/antiox15091182openalex-snapshot
PCSK9 Inhibition Attenuates Renal Oxidative Stress and Lipotoxicity in Diabetic Kidney Disease in Association with AMPK Activation
inferred← citeshttps://doi.org/10.3390/biom15091240openalex-snapshot
The Impact of PCSK9 on Diabetic Cardiomyopathy: Mechanisms and Implications
inferred← citeshttps://doi.org/10.3390/biomedicines11051500openalex-snapshot
Mitochondrial Dysfunction in Cardiac Diseases and Therapeutic Strategies
inferred← citeshttps://doi.org/10.3390/biomedicines9070793openalex-snapshot
PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology
inferred← citeshttps://doi.org/10.3390/cancers15051397openalex-snapshot
PCSK9 Inhibitors in Cancer Patients Treated with Immune-Checkpoint Inhibitors to Reduce Cardiovascular Events: New Frontiers in Cardioncology
inferred← citeshttps://doi.org/10.3390/cells11192972openalex-snapshot
PCSK9 Inhibition: From Current Advances to Evolving Future
inferred← citeshttps://doi.org/10.3390/diseases11040145openalex-snapshot
Lipoprotein(a) and Low-Molecular-Weight Apo(a) Phenotype as Determinants of New Cardiovascular Events in Patients with Premature Coronary Heart Disease
inferred← citeshttps://doi.org/10.3390/ijms22020660openalex-snapshot
Therapies for the Treatment of Cardiovascular Disease Associated with Type 2 Diabetes and Dyslipidemia
inferred← citeshttps://doi.org/10.3390/ijms22189884openalex-snapshot
Renal Ischemia/Reperfusion Early Induces Myostatin and PCSK9 Expression in Rat Kidneys and HK-2 Cells
inferred← citeshttps://doi.org/10.3390/ijms23126512openalex-snapshot
Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Deletion but Not Inhibition of Extracellular PCSK9 Reduces Infarct Sizes Ex Vivo but Not In Vivo
inferred← citeshttps://doi.org/10.3390/ijms24021585openalex-snapshot
Effects of Bempedoic Acid in Acute Myocardial Infarction in Rats: No Cardioprotection and No Hidden Cardiotoxicity
inferred← citeshttps://doi.org/10.3390/ijms26051921openalex-snapshot
PCSK9 Enhances Cardiac Fibrogenesis via the Activation of Toll-like Receptor and NLRP3 Inflammasome Signaling
inferred← citeshttps://doi.org/10.3390/jcm10132968openalex-snapshot
Reducing Cardiac Injury during ST-Elevation Myocardial Infarction: A Reasoned Approach to a Multitarget Therapeutic Strategy
inferred← citeshttps://doi.org/10.3390/jcm11133638openalex-snapshot
PCSK9 and Other Metabolic Targets to Counteract Ischemia/Reperfusion Injury in Acute Myocardial Infarction and Visceral Vascular Surgery
inferred← citeshttps://doi.org/10.3390/jpm13071077openalex-snapshot
The Concentration of PCSK9-Lp(a) Complexes and the Level of Blood Monocytes in Males with Coronary Atherosclerosis
inferred← citeshttps://doi.org/10.3390/metabo12030256openalex-snapshot
Insight into the Evolving Role of PCSK9
inferred← citeshttps://doi.org/10.4149/gpb_2019057openalex-snapshot
PCSK9 promotes the secretion of pro-inflammatory cytokines by macrophages to aggravate H/R-induced cardiomyocyte injury via activating NF-κB signalling
inferred← citeshttps://doi.org/10.4149/gpb_2022045openalex-snapshot
Effect on hypoxia/reoxygenation-induced cardiomyocyte injury and Pink1/Parkin pathway
inferred← citeshttps://doi.org/10.5603/cj.100585openalex-snapshot
Evaluating the effect of the antiPCSK9 vaccine on systemic inflammation and oxidative stress in an experimental mouse model
inferred← citeshttps://doi.org/10.56095/eaj.v2i2.47openalex-snapshot
PCSK9 in extrahepatic tissues: What can we expect from its inhibition?
inferred← citeshttps://doi.org/10.6084/m9.figshare.24873075openalex-snapshot
Additional file 1 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.24873194openalex-snapshot
Additional file 2 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.25264301openalex-snapshot
Additional file 1 of Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9
inferred← citeshttps://doi.org/10.6084/m9.figshare.25264462openalex-snapshot
Additional file 2 of Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656576openalex-snapshot
Additional file 3 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656579openalex-snapshot
Additional file 4 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656582openalex-snapshot
Additional file 5 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656585openalex-snapshot
Additional file 6 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656588openalex-snapshot
Additional file 7 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656591openalex-snapshot
Additional file 8 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.6084/m9.figshare.26656594openalex-snapshot
Additional file 9 of Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.7150/thno.80289openalex-snapshot
SIRT3 mediates the effects of PCSK9 inhibitors on inflammation, autophagy, and oxidative stress in endothelial cells
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