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Levels of trophectoderm mitochondrial DNA do not predict the reproductive potential of sibling embryos
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.fertnstert.2010.07.341openalex-snapshot
Mitochondrial DNA is significantly increased in aneuploid human embryos
inferredcites →https://doi.org/10.1016/j.fertnstert.2012.01.104openalex-snapshot
Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study
inferredcites →https://doi.org/10.1016/j.fertnstert.2012.01.115openalex-snapshot
Development and validation of an accurate quantitative real-time polymerase chain reaction–based assay for human blastocyst comprehensive chromosomal aneuploidy screening
inferredcites →https://doi.org/10.1016/j.fertnstert.2012.04.028openalex-snapshot
Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting
inferredcites →https://doi.org/10.1016/j.fertnstert.2013.04.035openalex-snapshot
Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial
inferredcites →https://doi.org/10.1016/j.fertnstert.2013.04.039openalex-snapshot
Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial
inferredcites →https://doi.org/10.1016/j.fertnstert.2015.05.022openalex-snapshot
Mitochondrial DNA content as a viability score in human euploid embryos: less is better
inferredcites →https://doi.org/10.1016/j.fertnstert.2015.06.017openalex-snapshot
Improving assisted reproductive technology pregnancy rates: excluding aneuploid and interrogating euploid embryos
inferredcites →https://doi.org/10.1016/j.fertnstert.2016.01.005openalex-snapshot
Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium
inferredcites →https://doi.org/10.1016/j.fertnstert.2016.09.028openalex-snapshot
Accurate quantitation of mitochondrial DNA reveals uniform levels in human blastocysts irrespective of ploidy, age, or implantation potential
inferredcites →https://doi.org/10.1016/j.mito.2010.09.012openalex-snapshot
Mitochondrial function in the human oocyte and embryo and their role in developmental competence
inferredcites →https://doi.org/10.1016/j.mito.2010.12.013openalex-snapshot
Dynamic regulation of mitochondrial function in preimplantation embryos and embryonic stem cells
inferredcites →https://doi.org/10.1016/j.semcdb.2008.12.013openalex-snapshot
Mitochondrial function and redox state in mammalian embryos
inferredcites →https://doi.org/10.1016/j.taap.2012.03.009openalex-snapshot
The effect of ethidium bromide and chloramphenicol on mitochondrial biogenesis in primary human fibroblasts
inferredcites →https://doi.org/10.1016/s0070-2153(06)77002-8openalex-snapshot
The Role of Mitochondrial Function in the Oocyte and Embryo
inferredcites →https://doi.org/10.1055/s-0035-1567821openalex-snapshot
Mitochondrial DNA Assessment to Determine Oocyte and Embryo Viability
inferredcites →https://doi.org/10.1083/jcb.91.3.227sopenalex-snapshot
Mitochondria: a historical review.
inferredcites →https://doi.org/10.1093/humrep/15.12.2621openalex-snapshot
Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competence
inferredcites →https://doi.org/10.1093/humrep/des020openalex-snapshot
Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates
inferredcites →https://doi.org/10.1093/molehr/gah243openalex-snapshot
Mitochondrial DNA content and 4977 bp deletion in unfertilized oocytes
inferredcites →https://doi.org/10.1093/oxfordjournals.humrep.a135954openalex-snapshot
Fertilization and early embryolgoy: ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer
inferredcites →https://doi.org/10.1097/gco.0000000000000274openalex-snapshot
Mitochondrial DNA as a biomarker for in-vitro fertilization outcome
inferredcites →https://doi.org/10.1097/mop.0b013e328332c6abopenalex-snapshot
Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew
inferredcites →https://doi.org/10.1111/j.1469-7793.2000.00057.xopenalex-snapshot
Mitochondria and calcium: from cell signalling to cell death
inferredcites →https://doi.org/10.1186/2047-217x-3-30openalex-snapshot
Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing
inferredcites →https://doi.org/10.1371/journal.pgen.1002161openalex-snapshot
Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy
inferredcites →https://doi.org/10.1371/journal.pgen.1005241openalex-snapshot
Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4144503openalex-extracted
Mitochondrial DNA Quantification Correlates with the Developmental Potential of Human Euploid Blastocysts but not with that of Mosaic Blastocysts
inferred← citeshttps://doi.org/10.1002/jcp.27713openalex-snapshot
Embryo quality, and not chromosome nondiploidy, affects mitochondrial DNA content in mouse blastocysts
inferred← citeshttps://doi.org/10.1002/mrd.23640openalex-snapshot
The role of mtDNA in oocyte quality and embryo development
inferred← citeshttps://doi.org/10.1007/s10815-017-1070-8openalex-snapshot
Mitochondrial DNA content is associated with ploidy status, maternal age, and oocyte maturation methods in mouse blastocysts
inferred← citeshttps://doi.org/10.1007/s10815-017-1072-6openalex-snapshot
Is mitochondrial DNA quantitation in blastocyst trophectoderm cells predictive of developmental competence and outcome in clinical IVF?
inferred← citeshttps://doi.org/10.1007/s10815-017-1090-4openalex-snapshot
Renaissance, reinvention, or rhetoric: mitochondria in reproductive medicine 2017
inferred← citeshttps://doi.org/10.1007/s10815-018-1113-9openalex-snapshot
Blastulation timing is associated with differential mitochondrial content in euploid embryos
inferred← citeshttps://doi.org/10.1007/s10815-018-1147-zopenalex-snapshot
Embryonal mitochondrial DNA: relationship to embryo quality and transfer outcomes
inferred← citeshttps://doi.org/10.1007/s10815-018-1265-7openalex-snapshot
Euploid embryos selected by an automated time-lapse system have superior SET outcomes than selected solely by conventional morphology assessment
inferred← citeshttps://doi.org/10.1007/s10815-019-01520-yopenalex-snapshot
Cleavage stage mitochondrial DNA is correlated with preimplantation human embryo development and ploidy status
inferred← citeshttps://doi.org/10.1007/s10815-019-01542-6openalex-snapshot
Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential
inferred← citeshttps://doi.org/10.1007/s10815-019-01544-4openalex-snapshot
mtDNA dynamics between cleavage-stage embryos and blastocysts
inferred← citeshttps://doi.org/10.1007/s10815-020-01795-6openalex-snapshot
Blastocyst mitochondrial DNA (mtDNA) is not affected by oocyte vitrification: a sibling oocyte study
inferred← citeshttps://doi.org/10.1007/s10815-020-02045-5openalex-snapshot
Suboptimal trophectoderm mitochondrial DNA level is associated with delayed blastocyst development
inferred← citeshttps://doi.org/10.1007/s10815-020-02050-8openalex-snapshot
Does blastocyst mitochondrial DNA content affect miscarriage rate in patients undergoing single euploid frozen embryo transfer?
inferred← citeshttps://doi.org/10.1007/s10815-021-02187-0openalex-snapshot
Euploidy rates are not affected when embryos are cultured in a continuous (CCM) or sequential culture medium (SCM): a sibling oocyte study
inferred← citeshttps://doi.org/10.1007/s10815-023-02952-3openalex-snapshot
The effect of vitrification on blastocyst mitochondrial DNA dynamics and gene expression profiles
inferred← citeshttps://doi.org/10.1007/s11010-024-05171-1openalex-snapshot
Mitochondrial dysfunction in pregnancy loss: a review
inferred← citeshttps://doi.org/10.1007/s43032-020-00163-0openalex-snapshot
Sperm Mitochondrial DNA Copy Number Is Not a Predictor of Intracytoplasmic Sperm Injection (ICSI) Cycle Outcomes
inferred← citeshttps://doi.org/10.1007/s43032-020-00422-0openalex-snapshot
Normalized Mitochondrial DNA Copy Number Can Optimize Pregnancy Outcome Prediction in IVF
inferred← citeshttps://doi.org/10.1007/s43032-021-00532-3openalex-snapshot
The Ratio of Mitochondrial DNA to Genomic DNA Copy Number in Cumulus Cell May Serve as a Biomarker of Embryo Quality in IVF Cycles
inferred← citeshttps://doi.org/10.1016/b978-0-12-813209-8.00020-0openalex-snapshot
Mitochondria Research in Human Reproduction
inferred← citeshttps://doi.org/10.1016/b978-0-12-816561-4.00009-0openalex-snapshot
Mitochondrial genetics
inferred← citeshttps://doi.org/10.1016/j.banm.2020.06.014openalex-snapshot
Pathologies mitochondriales & reproduction. Considérations cliniques, législatives, éthiques, anthropologiques
inferred← citeshttps://doi.org/10.1016/j.bmt.2023.06.001openalex-snapshot
Exploring mitochondrial DNA content as a novel biomarker to improve embryo implantation potential: A review
inferred← citeshttps://doi.org/10.1016/j.ejogrb.2025.114609openalex-snapshot
IVF add-ons: effectiveness, efficiency, safety, and additional costs – A position statement by the SIFES-MR
inferred← citeshttps://doi.org/10.1016/j.envpol.2019.113266openalex-snapshot
Air pollution and placental mitochondrial DNA copy number: Mechanistic insights and epidemiological challenges
inferred← citeshttps://doi.org/10.1016/j.envres.2023.115798openalex-snapshot
The prenatal environment and its influence on maternal and child mitochondrial DNA copy number and methylation: A review of the literature
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2017.09.022openalex-snapshot
Variables associated with mitochondrial copy number in human blastocysts: what can we learn from trophectoderm biopsies?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2017.10.007openalex-snapshot
Mitochondrial DNA quantity as a biomarker for blastocyst implantation potential
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2017.10.017openalex-snapshot
Mitochondrial DNA, a new biomarker of embryonic implantation potential: fact or fiction?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2018.02.062openalex-snapshot
Does the utilization of embryo glue give promise in donor embryo fets?
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2018.07.022openalex-snapshot
Metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2018.11.021openalex-snapshot
Mitochondrial DNA copy number as a predictor of embryo viability
inferred← citeshttps://doi.org/10.1016/j.rbmo.2018.02.007openalex-snapshot
The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights
inferred← citeshttps://doi.org/10.1016/j.rbmo.2019.03.043openalex-snapshot
Blastocysts with disproportionally high mtDNA copy number can result in healthy babies
inferred← citeshttps://doi.org/10.1016/j.rbmo.2019.03.045openalex-snapshot
Mitochondrial DNA (mtDNA) counts correlate to maternal age, day of biopsy and implantation potential
inferred← citeshttps://doi.org/10.1016/j.rbmo.2019.03.214openalex-snapshot
Births from embryos with highly elevated levels of mitochondrial DNA
inferred← citeshttps://doi.org/10.1016/j.rbmo.2020.04.011openalex-snapshot
Mitochondrial DNA content is not predictive of reproductive competence in euploid blastocysts
inferred← citeshttps://doi.org/10.1016/j.xfnr.2022.03.001openalex-snapshot
A review of factors influencing the implantation of euploid blastocysts after in vitro fertilization
inferred← citeshttps://doi.org/10.1016/j.xfss.2020.05.001openalex-snapshot
Mitochondrial DNA content decreases during in vitro human embryo development: insights into mitochondrial DNA variation in preimplantation embryos donated for research
inferred← citeshttps://doi.org/10.1017/9781316756744.026openalex-snapshot
Preimplantation Genetic Screening of Embryos for IVF
inferred← citeshttps://doi.org/10.1089/dna.2020.6271openalex-snapshot
Trophectoderm Mitochondrial DNA Content Associated with Embryo Quality and Day-5 Euploid Blastocyst Transfer Outcomes
inferred← citeshttps://doi.org/10.1093/hropen/hoac029openalex-snapshot
mtDNA content in cumulus cells does not predict development to blastocyst or implantation
inferred← citeshttps://doi.org/10.1093/hropen/hoad023openalex-snapshot
ESHRE good practice recommendations on recurrent implantation failure
inferred← citeshttps://doi.org/10.1093/hropen/hoae012openalex-snapshot
Blastocyst telomere length predicts successful implantation after frozen-thawed embryo transfer
inferred← citeshttps://doi.org/10.1093/hropen/hoy023openalex-snapshot
Comprehensive mitochondrial DNA analysis and IVF outcome
inferred← citeshttps://doi.org/10.1093/humrep/deab231openalex-snapshot
Extensive analysis of mitochondrial DNA quantity and sequence variation in human cumulus cells and assisted reproduction outcomes
inferred← citeshttps://doi.org/10.1093/humrep/deac016openalex-snapshot
Fluorescence lifetime imaging microscopy (FLIM) detects differences in metabolic signatures between euploid and aneuploid human blastocysts
inferred← citeshttps://doi.org/10.1093/humrep/dead184openalex-snapshot
Good practice recommendations on add-ons in reproductive medicine
inferred← citeshttps://doi.org/10.1093/humrep/dead268openalex-snapshot
Metabolic imaging of human embryos is predictive of ploidy status but is not associated with clinical pregnancy outcomes: a pilot trial
inferred← citeshttps://doi.org/10.1093/humrep/deae171openalex-snapshot
Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction
inferred← citeshttps://doi.org/10.1093/humrep/dex278openalex-snapshot
Mitochondrial DNA quantitation—making sense of contradictory reports
inferred← citeshttps://doi.org/10.1093/humrep/dex279openalex-snapshot
Reply: Mitochondrial DNA Quantification—the devil in the detail
inferred← citeshttps://doi.org/10.1093/humrep/dex292openalex-snapshot
Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study
inferred← citeshttps://doi.org/10.1093/humrep/dez011openalex-snapshot
Oxygen concentration alters mitochondrial structure and function in in vitro fertilized preimplantation mouse embryos
inferred← citeshttps://doi.org/10.1093/humrep/dez054openalex-snapshot
Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice
inferred← citeshttps://doi.org/10.1093/humrep/dez210openalex-snapshot
Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment
inferred← citeshttps://doi.org/10.1093/humupd/dmad010openalex-snapshot
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1093/molehr/gaz032openalex-snapshot
Non-invasive mitochondrial DNA quantification on Day 3 predicts blastocyst development: a prospective, blinded, multi-centric study
inferred← citeshttps://doi.org/10.1101/2022.02.01.478612openalex-snapshot
Molecular mechanisms involved in Atlantic halibut ( Hippoglossus hippoglossus ) egg quality: impairments at transcription and protein folding levels induce inefficient protein and energy homeostasis during early development
inferred← citeshttps://doi.org/10.1101/2022.10.14.512116openalex-snapshot
Aneuploidy in human embryos is associated with a maternal age-independent increase in mitochondrial DNA content and an enrichment of ultra-rare mitochondrial DNA variants
inferred← citeshttps://doi.org/10.1101/445940openalex-snapshot
The mitochondrial DNA content can not predict the embryo viability
inferred← citeshttps://doi.org/10.1101/629956openalex-snapshot
No association of mitochondrial DNA levels in trophectodermal cells with the developmental competence of the blastocyst and pregnancy outcomes
inferred← citeshttps://doi.org/10.1101/gr.252981.119openalex-snapshot
RNA-seq as a tool for evaluating human embryo competence
inferred← citeshttps://doi.org/10.1186/s12864-022-08859-0openalex-snapshot
Quantitative proteome profiling reveals molecular hallmarks of egg quality in Atlantic halibut: impairments of transcription and protein folding impede protein and energy homeostasis during early development
inferred← citeshttps://doi.org/10.1186/s12884-023-05760-wopenalex-snapshot
Mitochondrial DNA quantification correlates with the developmental potential of human euploid blastocysts but not with that of mosaic blastocysts
inferred← citeshttps://doi.org/10.1186/s12958-019-0501-zopenalex-snapshot
New Frontiers in IVF: mtDNA and autologous germline mitochondrial energy transfer
inferred← citeshttps://doi.org/10.1186/s12958-022-01033-xopenalex-snapshot
Age-related changes in Folliculogenesis and potential modifiers to improve fertility outcomes - A narrative review
inferred← citeshttps://doi.org/10.1210/endocr/bqaa001openalex-snapshot
Mitochondrial Dysfunction and Ovarian Aging
inferred← citeshttps://doi.org/10.1262/jrd.2020-097openalex-snapshot
Comparative analysis of cell-free DNA content in culture medium and mitochondrial DNA copy number in porcine parthenogenetically activated embryos
inferred← citeshttps://doi.org/10.1371/journal.pone.0227619openalex-snapshot
Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer
inferred← citeshttps://doi.org/10.1530/rep-17-0683openalex-snapshot
Chromosomal analysis in IVF: just how useful is it?
inferred← citeshttps://doi.org/10.1530/rep-18-0431openalex-snapshot
Mitochondria in early development: linking the microenvironment, metabolism and the epigenome
inferred← citeshttps://doi.org/10.1530/rep-18-0580openalex-snapshot
Mitochondria as a biomarker for IVF outcome
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2571158/v1openalex-snapshot
Mitochondrial DNA Quantification Correlates with the Developmental Potential of Human Euploid Blastocysts but not with that of Mosaic Blastocysts
inferred← citeshttps://doi.org/10.21608/ejhm.2022.258440openalex-snapshot
Total And Mitochondrial Cell Free DNA Quantification in Day 5 Embryos Culture Media Reflect Embryos Quality
inferred← citeshttps://doi.org/10.22363/2313-0245-2024-28-3-390-402openalex-snapshot
Mitochondrial DNA copy number level in the culture medium of human embryos as a factor in predicting the onset and prolongation of pregnancy
inferred← citeshttps://doi.org/10.23736/s0031-0808.18.03510-3openalex-snapshot
Mitochondria and reproduction: possibilities for testing and treatment
inferred← citeshttps://doi.org/10.23736/s2724-606x.23.05296-xopenalex-snapshot
How should the best human embryo in vitro be? Current and future challenges for embryo selection
inferred← citeshttps://doi.org/10.3389/fendo.2018.00327openalex-snapshot
Impact of Maternal Age on Oocyte and Embryo Competence
inferred← citeshttps://doi.org/10.3389/fendo.2019.00154openalex-snapshot
Past, Present, and Future Strategies for Enhanced Assessment of Embryo's Genome and Reproductive Competence in Women of Advanced Reproductive Age
inferred← citeshttps://doi.org/10.3389/fendo.2021.762976openalex-snapshot
Mitochondrial DNA Content May Not Be a Reliable Screening Biomarker for Live Birth After Single Euploid Blastocyst Transfer
inferred← citeshttps://doi.org/10.3389/fendo.2022.1066530openalex-snapshot
Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos
inferred← citeshttps://doi.org/10.3389/fendo.2024.1415865openalex-snapshot
Dependency of mitochondrial quantity on blastocyst timeline obscures its actual effect to pregnancy outcomes
inferred← citeshttps://doi.org/10.3390/antiox10010055openalex-snapshot
Qualitative and Quantitative Ovarian and Peripheral Blood Mitochondrial DNA (mtDNA) Alterations: Mechanisms and Implications for Female Fertility
inferred← citeshttps://doi.org/10.3390/cells11050797openalex-snapshot
The Role of Mitochondria in Human Fertility and Early Embryo Development: What Can We Learn for Clinical Application of Assessing and Improving Mitochondrial DNA?
inferred← citeshttps://doi.org/10.3390/cimb44010020openalex-snapshot
Mitochondrial DNA Copy Number in Cleavage Stage Human Embryos—Impact on Infertility Outcome
inferred← citeshttps://doi.org/10.3390/genes11060602openalex-snapshot
Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural Rearrangements
inferred← citeshttps://doi.org/10.3390/ijms22158353openalex-snapshot
Molecular Drivers of Developmental Arrest in the Human Preimplantation Embryo: A Systematic Review and Critical Analysis Leading to Mapping Future Research
inferred← citeshttps://doi.org/10.3390/ijms23115976openalex-snapshot
Does Trophectoderm Mitochondrial DNA Content Affect Embryo Developmental and Implantation Potential?
inferred← citeshttps://doi.org/10.3390/ijms25052834openalex-snapshot
When the Embryo Meets the Endometrium: Identifying the Features Required for Successful Embryo Implantation
inferred← citeshttps://doi.org/10.4103/jhrs.jhrs_103_21openalex-snapshot
Mitochondrial DNA Levels in Trophectodermal Cells Show No Association with Blastocyst Development and Pregnancy Outcomes
inferred← citeshttps://doi.org/10.6084/m9.figshare.26597516openalex-snapshot
Additional file 1 of Mitochondrial DNA quantification correlates with the developmental potential of human euploid blastocysts but not with that of mosaic blastocysts
inferred← citeshttps://doi.org/10.70675/ccb79427z2290z46abz95bez5077b63e4ed0openalex-snapshot
Study of mitochondrial metabolism during the development of human preimplantation embryos
inferred← citeshttps://doi.org/10.7759/cureus.27367openalex-snapshot
Association Between MitoScore, BMI, and Body Fat Percentage as a Predictive Marker for the Outcome of In-Vitro Fertilization (IVF)
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