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Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.antiviral.2013.06.021openalex-snapshot
Assessment of topical microbicides to prevent HIV-1 transmission: Concepts, testing, lessons learned
inferredcites →https://doi.org/10.1016/j.jpba.2011.05.039openalex-snapshot
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC–MS/MS detection
inferredcites →https://doi.org/10.1016/s0140-6736(12)60821-6openalex-snapshot
Global epidemiology of HIV infection in men who have sex with men
inferredcites →https://doi.org/10.1056/nejmoa1011205openalex-snapshot
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
inferredcites →https://doi.org/10.1056/nejmp1000069openalex-snapshot
AIDS in America — Forgotten but Not Gone
inferredcites →https://doi.org/10.1086/651481openalex-snapshot
Global Prevention of HIV Infection for Neglected Populations: Men Who Have Sex with Men
inferredcites →https://doi.org/10.1086/655661openalex-snapshot
Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV‐1 Entry via the CCR5 Co‐Receptor
inferredcites →https://doi.org/10.1089/aid.2012.0262openalex-snapshot
RMP-02/MTN-006: A Phase 1 Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Tenofovir 1% Gel Compared with Oral Tenofovir Disoproxil Fumarate
inferredcites →https://doi.org/10.1089/aid.2013.0189openalex-snapshot
Isoosmolar Enemas Demonstrate Preferential Gastrointestinal Distribution, Safety, and Acceptability Compared with Hyperosmolar and Hypoosmolar Enemas as a Potential Delivery Vehicle for Rectal Microbicides
inferredcites →https://doi.org/10.1093/jac/dks422openalex-snapshot
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques
inferredcites →https://doi.org/10.1097/01.aids.0000210608.70762.c3openalex-snapshot
Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
inferredcites →https://doi.org/10.1097/olq.0b013e3181901ccfopenalex-snapshot
Anal Intercourse Among Young Heterosexuals in Three Sexually Transmitted Disease Clinics in the United States
inferredcites →https://doi.org/10.1111/j.1541-0420.2009.01189.xopenalex-snapshot
Assessing Vaccine Effects in Repeated Low‐Dose Challenge Experiments
inferredcites →https://doi.org/10.1111/j.1743-6109.2010.02012.xopenalex-snapshot
Sexual Behavior in the United States: Results from a National Probability Sample of Men and Women Ages 14–94
inferredcites →https://doi.org/10.1126/science.1193748openalex-snapshot
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
inferredcites →https://doi.org/10.1126/scitranslmed.3000391openalex-snapshot
Intermittent Prophylaxis with Oral Truvada Protects Macaques from Rectal SHIV Infection
inferredcites →https://doi.org/10.1126/scitranslmed.3007701openalex-snapshot
Postexposure Protection of Macaques from Vaginal SHIV Infection by Topical Integrase Inhibitors
inferredcites →https://doi.org/10.1128/aac.02522-14openalex-snapshot
Enhanced Antiretroviral Therapy in Rhesus Macaques Improves RT-SHIV Viral Decay Kinetics
inferredcites →https://doi.org/10.1128/aac.42.6.1484openalex-snapshot
Antiviral Activities of 9- R -2-Phosphonomethoxypropyl Adenine (PMPA) and Bis(isopropyloxymethylcarbonyl)PMPA against Various Drug-Resistant Human Immunodeficiency Virus Strains
inferredcites →https://doi.org/10.1128/aac.49.11.4721-4732.2005openalex-snapshot
Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity
inferredcites →https://doi.org/10.1128/jvi.01073-09openalex-snapshot
Complete Protection from Repeated Vaginal Simian-Human Immunodeficiency Virus Exposures in Macaques by a Topical Gel Containing Tenofovir Alone or with Emtricitabine
inferredcites →https://doi.org/10.1128/jvi.01204-13openalex-snapshot
Lack of Prophylactic Efficacy of Oral Maraviroc in Macaques despite High Drug Concentrations in Rectal Tissues
inferredcites →https://doi.org/10.1128/jvi.05842-11openalex-snapshot
Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue
inferredcites →https://doi.org/10.1128/jvi.75.18.8390-8399.2001openalex-snapshot
A Preponderance of CCR5+CXCR4+Mononuclear Cells Enhances Gastrointestinal Mucosal Susceptibility to Human Immunodeficiency Virus Type 1 Infection
inferredcites →https://doi.org/10.1136/sti.2008.035287openalex-snapshot
Heterosexual anal intercourse among community and clinical settings in Cape Town, South Africa
inferredcites →https://doi.org/10.1182/blood-2012-06-436345openalex-snapshot
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial
inferredcites →https://doi.org/10.1186/1471-2458-11-807openalex-snapshot
Heterosexual anal intercourse and HIV infection risks in the context of alcohol serving venues, Cape Town, South Africa
inferredcites →https://doi.org/10.1371/journal.pmed.0050028openalex-snapshot
Prevention of Rectal SHIV Transmission in Macaques by Daily or Intermittent Prophylaxis with Emtricitabine and Tenofovir
inferredcites →https://doi.org/10.1371/journal.pmed.0050157openalex-snapshot
Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel
inferredcites →https://doi.org/10.1371/journal.pone.0009310openalex-snapshot
In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide
inferredcites →https://doi.org/10.1371/journal.pone.0025974openalex-snapshot
A Multi-Compartment, Single and Multiple Dose Pharmacokinetic Study of the Vaginal Candidate Microbicide 1% Tenofovir Gel
inferredcites →https://doi.org/10.1371/journal.pone.0028047openalex-snapshot
SHIV-162P3 Infection of Rhesus Macaques Given Maraviroc Gel Vaginally Does Not Involve Resistant Viruses
inferredcites →https://doi.org/10.1371/journal.pone.0050632openalex-snapshot
Prevention of Vaginal SHIV Transmission in Macaques by a Coitally-Dependent Truvada Regimen
inferredcites →https://doi.org/10.1371/journal.pone.0060147openalex-snapshot
A Phase 1 Randomized, Double Blind, Placebo Controlled Rectal Safety and Acceptability Study of Tenofovir 1% Gel (MTN-007)
inferredcites →https://doi.org/10.1371/journal.pone.0102585openalex-snapshot
Development of HIV-1 Rectal-Specific Microbicides and Colonic Tissue Evaluation
inferredcites →https://doi.org/10.1371/journal.pone.0106196openalex-snapshot
A Multi-Compartment Single and Multiple Dose Pharmacokinetic Comparison of Rectally Applied Tenofovir 1% Gel and Oral Tenofovir Disoproxil Fumarate
inferredcites →https://doi.org/10.2165/11590700-000000000-00000openalex-snapshot
Clinical Utility of Maraviroc
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/82_2017_73openalex-snapshot
Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy
inferred← citeshttps://doi.org/10.1007/s11262-020-01816-7openalex-snapshot
In vitro inhibitory effect of maraviroc on the association of the simian immunodeficiency virus envelope glycoprotein with CCR5
inferred← citeshttps://doi.org/10.1016/j.actbio.2017.10.024openalex-snapshot
In situ depot formation of anti-HIV fusion-inhibitor peptide in recombinant protein polymer hydrogel
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2017.03.040openalex-snapshot
Nanoemulgel using a bicephalous heterolipid as a novel approach to enhance transdermal permeation of tenofovir
inferred← citeshttps://doi.org/10.1016/j.cyto.2018.02.018openalex-snapshot
CCR5: Established paradigms and new frontiers for a ‘celebrity’ chemokine receptor
inferred← citeshttps://doi.org/10.1016/j.ebiom.2022.104338openalex-snapshot
Pharmacokinetics and efficacy of topical inserts containing tenofovir alafenamide fumarate and elvitegravir administered rectally in macaques
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104409openalex-snapshot
The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans
inferred← citeshttps://doi.org/10.1038/emi.2017.26openalex-snapshot
A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins
inferred← citeshttps://doi.org/10.1038/s41467-026-72907-6openalex-snapshot
Pharmacological markers of HIV prevention for oral pre-exposure prophylaxis in men who have sex with men
inferred← citeshttps://doi.org/10.1089/aid.2015.0315openalex-snapshot
Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues
inferred← citeshttps://doi.org/10.1089/aid.2021.0096openalex-snapshot
A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study)
inferred← citeshttps://doi.org/10.1093/infdis/jiaf286openalex-snapshot
Anal Sex and Tenofovir Douche Sequence Impacts Colorectal Distribution of HIV Surrogate and Douche: DREAM-02
inferred← citeshttps://doi.org/10.1093/infdis/jiy301openalex-snapshot
Efficacy of Vaginally Administered Gel Containing Emtricitabine and Tenofovir Against Repeated Rectal Simian Human Immunodeficiency Virus Exposures in Macaques
inferred← citeshttps://doi.org/10.1093/jac/dkab293openalex-snapshot
Pharmacokinetics of vaginally applied integrase inhibitors in macaques
inferred← citeshttps://doi.org/10.1093/jac/dkv335openalex-snapshot
Drug transporter gene expression in human colorectal tissue and cell lines: modulation with antiretrovirals for microbicide optimization
inferred← citeshttps://doi.org/10.1097/coh.0000000000000738openalex-snapshot
The predictive value of macaque models of preexposure prophylaxis for HIV prevention
inferred← citeshttps://doi.org/10.1097/qad.0000000000002038openalex-snapshot
The pharmacokinetics, pharmacodynamics, and mucosal responses to maraviroc-containing pre-exposure prophylaxis regimens in MSM
inferred← citeshttps://doi.org/10.1128/aac.01644-17openalex-snapshot
Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection
inferred← citeshttps://doi.org/10.1128/jvi.00576-18openalex-snapshot
Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques
inferred← citeshttps://doi.org/10.2147/dddt.s90580openalex-snapshot
Maraviroc: a review of its use in HIV infection and beyond
inferred← citeshttps://doi.org/10.2147/hiv.s291065openalex-snapshot
Mucoadhesive Microspheres of Maraviroc and Tenofovir Designed for Pre-Exposure Prophylaxis of HIV-1: An in vitro Assessment of the Effect on Vaginal Lactic Acid Bacteria Microflora
inferred← citeshttps://doi.org/10.2174/1573407216999200612103526openalex-snapshot
Bioactives in Disease Prevention and Health Promotion: Exploiting Combinatorial Effects
inferred← citeshttps://doi.org/10.2174/1573412917666210823091007openalex-snapshot
Maraviroc Oral Disintegration Tablet: Analytical Design of Experiments (DoE) for Assessment and Comparison of In vitro Dissolution Profiles
inferred← citeshttps://doi.org/10.3390/books978-3-03897-993-7openalex-snapshot
Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions
inferred← citeshttps://doi.org/10.3390/medicines5040120openalex-snapshot
Pathogenic Viruses Commonly Present in the Oral Cavity and Relevant Antiviral Compounds Derived from Natural Products
inferred← citeshttps://doi.org/10.3390/pharmaceutics13081110openalex-snapshot
Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention
inferred← citeshttps://doi.org/10.7448/ias.18.1.20301openalex-snapshot
Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?
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