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BRAFV600E mutation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1097-0142(19860515)57:10<2006::aid-cncr2820571022>3.0.co;2-6openalex-snapshot

Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases

inferredcites →https://doi.org/10.1007/s00401-011-0841-zopenalex-snapshot

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

inferredcites →https://doi.org/10.1007/s00401-013-1120-yopenalex-snapshot

BRAFV600E mutation is a negative prognosticator in pediatric ganglioglioma

inferredcites →https://doi.org/10.1016/0092-8674(92)90407-4openalex-snapshot

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

inferredcites →https://doi.org/10.1016/j.jmoldx.2012.09.001openalex-snapshot

Detection of BRAF p.V600E Mutations in Melanomas

inferredcites →https://doi.org/10.1016/j.nec.2008.07.004openalex-snapshot

Malignant Peripheral Nerve Sheath Tumors

inferredcites →https://doi.org/10.1038/356713a0openalex-snapshot

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

inferredcites →https://doi.org/10.1038/nature00766openalex-snapshot

Mutations of the BRAF gene in human cancer

inferredcites →https://doi.org/10.1093/neuonc/not146openalex-snapshot

BRAF-V600E mutation in pediatric and adult glioblastoma

inferredcites →https://doi.org/10.1097/nen.0b013e3182656ef8openalex-snapshot

BRAF Duplications and MAPK Pathway Activation Are Frequent in Gliomas of the Optic Nerve Proper

inferredcites →https://doi.org/10.1111/his.12021openalex-snapshot

BRAF V600E and KRAS G12S mutations in peripheral nerve sheath tumours

inferredcites →https://doi.org/10.1136/jmg.39.5.311openalex-snapshot

Malignant peripheral nerve sheath tumours in neurofibromatosis 1

inferredcites →https://doi.org/10.1542/peds.2007-3204openalex-snapshot

Neurofibromatosis Type 1 Revisited

inferredcites →https://doi.org/10.2174/187152011795347469openalex-snapshot

BRAF as a Target for Cancer Therapy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4170164openalex-extracted

inferred← citeshttps://doi.org/10.1002/cam4.3103openalex-snapshot

BRAF mutation and its inhibitors in sarcoma treatment

inferred← citeshttps://doi.org/10.1002/cncr.30455openalex-snapshot

Clinical genomic profiling identifies TYK2 mutation and overexpression in patients with neurofibromatosis type 1‐associated malignant peripheral nerve sheath tumors

inferred← citeshttps://doi.org/10.1002/path.6391openalex-snapshot

Alternative driver pathways in peripheral nerve sheath tumors – including DICER1 and/or KRAS alterations

inferred← citeshttps://doi.org/10.1007/978-3-030-77633-6_2openalex-snapshot

Genetics of Nerve Tumors

inferred← citeshttps://doi.org/10.1007/978-3-319-30654-4_22openalex-snapshot

Malignant Peripheral Nerve Sheath Tumors

inferred← citeshttps://doi.org/10.1007/978-3-540-35280-8_1493openalex-snapshot

Malignant Peripheral Nerve Sheath Tumor

inferred← citeshttps://doi.org/10.1007/s11060-014-1553-8openalex-snapshot

TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors

inferred← citeshttps://doi.org/10.1007/s13402-025-01054-9openalex-snapshot

From benign neurofibromas to malignant peripheral nerve sheath tumors (MPNST): a gaming among multiple factors

inferred← citeshttps://doi.org/10.1016/b978-0-12-812100-9.00021-8openalex-snapshot

Growth Factor Signaling Pathways and Targeted Therapy

inferred← citeshttps://doi.org/10.1016/b978-0-323-37754-6.50164-0openalex-snapshot

Neurofibroma

inferred← citeshttps://doi.org/10.1016/b978-0-323-44592-4.50096-2openalex-snapshot

Malignant Peripheral Nerve Sheath Tumor

inferred← citeshttps://doi.org/10.1016/b978-0-443-27356-8.00061-9openalex-snapshot

Growth factor signaling pathways and targeted therapy

inferred← citeshttps://doi.org/10.1016/b978-0-7020-6616-0.00023-2openalex-snapshot

Neurogenic tumors

inferred← citeshttps://doi.org/10.1016/j.expneurol.2017.08.014openalex-snapshot

The promise of signal transduction in genetically driven sarcomas of the nerve

inferred← citeshttps://doi.org/10.1016/j.humpath.2022.08.005openalex-snapshot

Prevalence and Detection of Actionable BRAF V600 and NRAS Q61 Mutations in Malignant Peripheral Nerve Sheath Tumor by Droplet Digital PCR

inferred← citeshttps://doi.org/10.1016/j.isci.2023.106096openalex-snapshot

Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis

inferred← citeshttps://doi.org/10.1016/j.oncohp.2016.04.005openalex-snapshot

Les inhibiteurs de BRAF et leurs applications potentielles en pédiatrie

inferred← citeshttps://doi.org/10.1016/j.survophthal.2016.08.002openalex-snapshot

Orbital peripheral nerve sheath tumors

inferred← citeshttps://doi.org/10.1016/j.yexmp.2017.11.010openalex-snapshot

Expression of the BRAF L597Q mutation in sporadic neurofibromas of the upper extremity

inferred← citeshttps://doi.org/10.1038/s41388-022-02290-1openalex-snapshot

Malignant peripheral nerve sheath tumor: models, biology, and translation

inferred← citeshttps://doi.org/10.1038/s41597-020-0508-5openalex-snapshot

A clinically and genomically annotated nerve sheath tumor biospecimen repository

inferred← citeshttps://doi.org/10.1038/s41598-017-15183-1openalex-snapshot

The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation

inferred← citeshttps://doi.org/10.1038/s41598-021-85055-2openalex-snapshot

Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line

inferred← citeshttps://doi.org/10.1038/s41698-026-01439-5openalex-snapshot

Sox2 protein stability is enhanced by BRafV600E and Pten deletion in adult neural stem/progenitor cells

inferred← citeshttps://doi.org/10.1055/b-0045-210207openalex-snapshot

14 Cellular and Molecular Biology of the Spinal Cord, Meningeal, and Peripheral Nerve Neoplasms

inferred← citeshttps://doi.org/10.1080/14728222.2024.2306344openalex-snapshot

Epigenetic determinants in soft tissue sarcomas: molecular mechanisms and therapeutic targets

inferred← citeshttps://doi.org/10.1093/neuros/nyaa455openalex-snapshot

Genetic Events and Signaling Mechanisms Underlying Schwann Cell Fate in Development and Cancer

inferred← citeshttps://doi.org/10.1093/noajnl/vdz026openalex-snapshot

Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1

inferred← citeshttps://doi.org/10.1101/2022.05.07.491026openalex-snapshot

A detailed landscape of genomic alterations in malignant peripheral nerve sheath tumor cell lines challenges the current MPNST diagnosis

inferred← citeshttps://doi.org/10.1111/neup.12293openalex-snapshot

Gliosarcomas lack BRAFV600E mutation, but a subset exhibit β‐catenin nuclear localization

inferred← citeshttps://doi.org/10.1155/2021/4614185openalex-snapshot

Malignant Glandular Triton Tumor Arising in the Radial Nerve with Prolonged Survival: A Case Report and Review of the Literature

inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-14-3049openalex-snapshot

Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma

inferred← citeshttps://doi.org/10.1159/000509773openalex-snapshot

Durable Complete Response of a Recurrent Mesencephalic Glioblastoma Treated with Trametinib and Low-Dose Dabrafenib in a Patient with Neurofibromatosis Type 1

inferred← citeshttps://doi.org/10.1242/dmm.052471openalex-snapshot

A novel murine model for sporadic, malignant peripheral nerve sheath tumors, driven by BrafV600E and Pten loss

inferred← citeshttps://doi.org/10.18632/oncotarget.25195openalex-snapshot

Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST

inferred← citeshttps://doi.org/10.18632/oncotarget.28606openalex-snapshot

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors

inferred← citeshttps://doi.org/10.19070/2377-8075-17000101openalex-snapshot

Neurofibromatosis type I with an Rare Oral Manifestation

inferred← citeshttps://doi.org/10.2217/cns-2016-0024openalex-snapshot

The role of the immune system in neurofibromatosis type 1-associated nervous system tumors

inferred← citeshttps://doi.org/10.3389/fonc.2020.574974openalex-snapshot

BRAF Alteration in Central and Peripheral Nervous System Tumors

inferred← citeshttps://doi.org/10.3389/fonc.2022.911043openalex-snapshot

Epidemiology, Characteristic, and Prognostic Factors of Primary Sporadic Intradural Malignant Peripheral Nerve Sheath Tumor in the Spinal Canal: A Systematic Literature Review

inferred← citeshttps://doi.org/10.3390/genes11060691openalex-snapshot

From Genes to -Omics: The Evolving Molecular Landscape of Malignant Peripheral Nerve Sheath Tumor

inferred← citeshttps://doi.org/10.5812/ijcm.7211openalex-snapshot

Simultaneous Presentation of Cerebellopontine Angle Pleomorphic Xanthoastrocytoma and Malignant Melanoma in a Known Case of Neurofibromatosis 1; Probable Role of BRAF Gene: A Case Report and Review of Literature

inferred← citeshttps://doi.org/10.6004/jnccn.2018.7033openalex-snapshot

Genomic Profiling in Patients With Malignant Peripheral Nerve Sheath Tumors Reveals Multiple Pathways With Targetable Mutations

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