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Absolute Lymphocyte Count Thresholds: A Simple, Readily Available Tool to Predict the Risk of Cytomegalovirus Infection After Transplantation

https://doi.org/10.1093/ofid/ofy230
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jmv.23539openalex-snapshot
High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy
inferredcites →https://doi.org/10.1002/lt.23991openalex-snapshot
Pretransplant Lymphopenia Is a Novel Prognostic Factor in Cytomegalovirus and Noncytomegalovirus Invasive Infections After Liver Transplantation
inferredcites →https://doi.org/10.1016/j.hemonc.2017.05.001openalex-snapshot
Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation
inferredcites →https://doi.org/10.1080/146532402317251473openalex-snapshot
Adoptive transfer of Ag-specific T cells to prevent CMV disease after allogeneic stem-cell transplantation
inferredcites →https://doi.org/10.1093/cid/cit096openalex-snapshot
Virologic Suppression Measured by a Cytomegalovirus (CMV) DNA Test Calibrated to the World Health Organization International Standard Is Predictive of CMV Disease Resolution in Transplant Recipients
inferredcites →https://doi.org/10.1093/cid/ciw668openalex-snapshot
Definitions of Cytomegalovirus Infection and Disease in Transplant Patients for Use in Clinical Trials: Table 1.
inferredcites →https://doi.org/10.1093/cid/ciy295openalex-snapshot
Absolute Lymphocyte Count: A Predictor of Recurrent Cytomegalovirus Disease in Solid Organ Transplant Recipients
inferredcites →https://doi.org/10.1097/mot.0b013e32834016b9openalex-snapshot
T-cell therapy for cytomegalovirus infection
inferredcites →https://doi.org/10.1097/tp.0000000000002396openalex-snapshot
Clinical Correlation of Cytomegalovirus Infection With CMV-specific CD8+ T-cell Immune Competence Score and Lymphocyte Subsets in Solid Organ Transplant Recipients
inferredcites →https://doi.org/10.1111/ajt.12103openalex-snapshot
Cytomegalovirus in Solid Organ Transplantation
inferredcites →https://doi.org/10.1111/j.1399-0012.2009.01076.xopenalex-snapshot
The impact of invasive fungal diseases on survival after lung transplantation
inferredcites →https://doi.org/10.1172/jci90599openalex-snapshot
Immunotherapy for transplantation-associated viral infections

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4005580openalex-extracted
The Establishment of a CMV-Specific CD8 + T-Cell Threshold by Kinetic Modelling for Prediction of Post-HSCT Reactivation
inferred← citeshttps://doi.org/10.1002/ajh.26312openalex-snapshot
Clinical risk factors and prognostic model for idiopathic inflammatory demyelinating diseases after haploidentical hematopoietic stem cell transplantation in patients with hematological malignancies
inferred← citeshttps://doi.org/10.1002/jmv.70949openalex-snapshot
Torque Teno Virus Viral Load as a Predictive Marker of Serotype‐Specific Antibody Response Following the 13‐Valent Conjugated Pneumococcal Vaccine in Adult Kidney Transplant Recipients: A Cohort Study
inferred← citeshttps://doi.org/10.1007/978-3-031-28797-8_10openalex-snapshot
Cytomegalovirus Diseases in Hematopoietic Cell Transplant Recipients
inferred← citeshttps://doi.org/10.1016/j.ajt.2023.10.007openalex-snapshot
Risk of cytomegalovirus infection and subsequent allograft failure after pancreas transplantation
inferred← citeshttps://doi.org/10.1016/j.bneo.2025.100097openalex-snapshot
Risk factors and clinical impact of cytomegalovirus DNAemia in patients with multiple myeloma treated with teclistamab
inferred← citeshttps://doi.org/10.1016/j.clml.2026.05.008openalex-snapshot
Prospective Study of Cytomegalovirus Reactivation in Patients With Multiple Myeloma Receiving Anti-CD38 and BCMA Therapies
inferred← citeshttps://doi.org/10.1016/j.cmi.2022.07.001openalex-snapshot
Cytomegalovirus infection in transplant recipients: newly approved additions to our armamentarium
inferred← citeshttps://doi.org/10.1016/j.cmi.2023.03.020openalex-snapshot
Oral antiviral drugs for treatment of cytomegalovirus in transplant recipients
inferred← citeshttps://doi.org/10.1016/j.diagmicrobio.2026.117651openalex-snapshot
Machine learning–driven analysis of CMV-DNA levels and associated factors
inferred← citeshttps://doi.org/10.1016/j.ekir.2026.107088openalex-snapshot
Cytomegalovirus: Updated Approach to Management for Kidney Transplant Recipients
inferred← citeshttps://doi.org/10.1016/j.ijid.2025.108311openalex-snapshot
Logical versus absolute lymphocyte count–guided preemptive therapy for cytomegalovirus prevention in kidney transplant recipients: a randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105340openalex-snapshot
The establishment of a cytomegalovirus -specific CD8+ T-cell threshold by kinetic modeling for the prediction of post-hemopoietic stem cell transplant reactivation
inferred← citeshttps://doi.org/10.1016/j.jhlto.2023.100047openalex-snapshot
Cytomegalovirus infection in heart transplant recipients: Epidemiology, risk factors, and long-term outcomes from a major transplant center in the United States
inferred← citeshttps://doi.org/10.1016/j.semnephrol.2023.151486openalex-snapshot
Diagnosis, Prevention, and Treatment of Infections in Kidney Transplantation
inferred← citeshttps://doi.org/10.1016/j.transproceed.2019.01.129openalex-snapshot
Predictive Value of the Combination of Peripheral Blood Lymphocyte Count and Urinary Cytology in BK Polyomavirus–associated Nephropathy
inferred← citeshttps://doi.org/10.1016/j.trre.2024.100875openalex-snapshot
Management of cytomegalovirus in adult solid organ transplant patients: GESITRA-IC-SEIMC, CIBERINFEC, and SET recommendations update
inferred← citeshttps://doi.org/10.1038/s41598-020-80790-4openalex-snapshot
Post-transplant absolute lymphocyte count predicts early cytomegalovirus infection after heart transplantation
inferred← citeshttps://doi.org/10.1080/14787210.2020.1733976openalex-snapshot
Predictive tools to determine risk of infection in kidney transplant recipients
inferred← citeshttps://doi.org/10.1080/14787210.2024.2399647openalex-snapshot
Management of resistant and refractory cytomegalovirus infections after transplantation
inferred← citeshttps://doi.org/10.1080/1744666x.2024.2384060openalex-snapshot
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review
inferred← citeshttps://doi.org/10.1080/23808993.2021.1964951openalex-snapshot
Individualized management of cytomegalovirus in solid organ transplant recipients
inferred← citeshttps://doi.org/10.1093/cid/ciaa1800openalex-snapshot
Association Between Lymphopenia at 1 Month Posttransplant and Infectious Outcomes or Death in Heart Transplant Recipients
inferred← citeshttps://doi.org/10.1093/infdis/jiz452openalex-snapshot
Differences in Duration and Degree of Cytomegalovirus DNAemia Observed With Two Standardized Quantitative Nucleic Acid Tests and Implications for Clinical Care
inferred← citeshttps://doi.org/10.1093/jac/dkaf243openalex-snapshot
Dynamics of dual CMV and EBV co-reactivation and emergence of resistance in an HSCT recipient
inferred← citeshttps://doi.org/10.1093/ofid/ofab199openalex-snapshot
Predictors of CMV Infection in CMV-Seropositive Kidney Transplant Recipients: Impact of Pretransplant CMV-Specific Humoral Immunity
inferred← citeshttps://doi.org/10.1093/ofid/ofab248openalex-snapshot
A Prospective Study of Cytomegalovirus-Specific Cell-Mediated Immune Monitoring and Cytomegalovirus Infection in Patients With Active Systemic Lupus Erythematosus Receiving Immunosuppressants
inferred← citeshttps://doi.org/10.1093/ofid/ofag056openalex-snapshot
Diabetes Mellitus is a Risk Factor for Developing CMV Retinitis in Solid Organ Transplant Recipients: A Case-control Study
inferred← citeshttps://doi.org/10.1097/tp.0000000000004360openalex-snapshot
Absolute Lymphocyte Count as a Marker for Cytomegalovirus Infection After Heart Transplantation
inferred← citeshttps://doi.org/10.1097/tp.0000000000004616openalex-snapshot
The Best Method for CMV Prevention in High-risk Kidney Transplant Recipients? Either, per National Norwegian Transplant Database: Commentary on Blom et al, Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic…
inferred← citeshttps://doi.org/10.1097/tp.0000000000004855openalex-snapshot
What’s New: Updates on Cytomegalovirus in Solid Organ Transplantation
inferred← citeshttps://doi.org/10.1097/tp.0000000000004870openalex-snapshot
QuantiFERON-CMV as a Predictor of CMV Events During Preemptive Therapy in CMV-seropositive Kidney Transplant Recipients
inferred← citeshttps://doi.org/10.1097/tp.0000000000004908openalex-snapshot
Conversion to mTOR Inhibitor to Reduce the Incidence of Cytomegalovirus Recurrence in Kidney Transplant Recipients Receiving Preemptive Treatment: A Prospective, Randomized Trial
inferred← citeshttps://doi.org/10.1097/tp.0000000000005374openalex-snapshot
The Fourth International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation
inferred← citeshttps://doi.org/10.1097/txd.0000000000001542openalex-snapshot
A Clinical Model to Predict the Occurrence of Select High-risk Infections in the First Year Following Heart Transplantation
inferred← citeshttps://doi.org/10.1097/txd.0000000000001846openalex-snapshot
Sex- and Age-based Comparison of Key Clinical Markers of Immunity After Heart and Kidney Transplantation
inferred← citeshttps://doi.org/10.1111/ctr.13512openalex-snapshot
Cytomegalovirus in solid organ transplant recipients—Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice
inferred← citeshttps://doi.org/10.1111/ctr.15135openalex-snapshot
BK polyomavirus DNAemia in pancreas transplant recipients compared to pancreas–kidney recipients
inferred← citeshttps://doi.org/10.1111/ctr.15143openalex-snapshot
Clinical utility of a cytomegalovirus‐specific T cell assay in assessing the risk of post‐prophylaxis cytomegalovirus infection and post‐treatment relapse
inferred← citeshttps://doi.org/10.1111/ctr.70342openalex-snapshot
Risk Factors and Outcomes of Recurrent Cytomegalovirus Infection in Heart Transplant Recipients
inferred← citeshttps://doi.org/10.1111/imr.70104openalex-snapshot
Sex Differences in Alloimmunity and Other Immunological Considerations in Organ Transplantation
inferred← citeshttps://doi.org/10.1111/tid.13189openalex-snapshot
The impact of recurrent cytomegalovirus infection on long‐term survival in solid organ transplant recipients
inferred← citeshttps://doi.org/10.1111/tid.13489openalex-snapshot
Absolute lymphocyte count as marker of cytomegalovirus and allograft rejection: Is there a “Safe Corridor” after kidney transplantation?
inferred← citeshttps://doi.org/10.1111/tid.13864openalex-snapshot
Cytomegalovirus antiviral stewardship in solid organ transplant recipients: A new gold standard
inferred← citeshttps://doi.org/10.1111/tid.14020openalex-snapshot
Pathogen‐agnostic immune biomarkers that predict infection after solid organ transplantation
inferred← citeshttps://doi.org/10.1111/tid.14116openalex-snapshot
Like watching a soccer game through a keyhole: Cytomegalovirus cell‐mediated immunity incompletely reveals risk for clinically significant cytomegalovirus reactivation in cord blood transplant recipients
inferred← citeshttps://doi.org/10.1111/tid.14233openalex-snapshot
Five‐year single‐center analysis of cytomegalovirus viremia in kidney transplant recipients and possible implication for novel prophylactic therapy approaches
inferred← citeshttps://doi.org/10.1111/tid.14239openalex-snapshot
How low should we go? Potential and challenges of ultrasensitive CMV assays and solid organ transplantation
inferred← citeshttps://doi.org/10.1111/tid.70010openalex-snapshot
Impact of Severe Persistent BK Polyomavirus on Graft Function and Quality of Life Outcomes in Kidney Transplant Recipients
inferred← citeshttps://doi.org/10.1111/tid.70314openalex-snapshot
Incidence and Risk of Cytomegalovirus Infection After Intestine Transplantation
inferred← citeshttps://doi.org/10.1128/cmr.00043-19openalex-snapshot
Progress and Challenges in the Prevention, Diagnosis, and Management of Cytomegalovirus Infection in Transplantation
inferred← citeshttps://doi.org/10.11606/t.5.2023.tde-08052023-170032openalex-snapshot
Predição de infecção clinicamente relevante por citomegalovírus utilizando o teste Quantiferon-CMV em receptores de transplante renal CMV-soropositivos
inferred← citeshttps://doi.org/10.1182/bloodadvances.2020003074openalex-snapshot
A risk score for predicting hospitalization for community-acquired pneumonia in ITP using nationally representative data
inferred← citeshttps://doi.org/10.1186/s12879-020-4787-4openalex-snapshot
Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine staining to predict clinically significant CMV events
inferred← citeshttps://doi.org/10.2147/idr.s547565openalex-snapshot
Beyond Thresholds: CMV Replication Kinetics as Early Predictors of Clinical Risk in Transplant Recipients
inferred← citeshttps://doi.org/10.3324/haematol.2019.229252openalex-snapshot
Standardized monitoring of cytomegalovirus-specific immunity can improve risk stratification of recurrent cytomegalovirus reactivation after hematopoietic stem cell transplantation
inferred← citeshttps://doi.org/10.3389/ti.2023.11527openalex-snapshot
Utility of the Interferon-Gamma Enzyme-Linked Immunosorbent Spot Assay to Predict Risk of Cytomegalovirus Infection in Kidney Transplant Recipients
inferred← citeshttps://doi.org/10.3390/v16111781openalex-snapshot
Cytomegalovirus Infection After Solid Organ Transplantation: How I Use Cell-Mediated Immune Assays for Management
inferred← citeshttps://doi.org/10.36660/abc.20230588openalex-snapshot
Contagem Absoluta de Linfócitos: um Preditor de PCR Sérica Positiva para o Trypanosoma cruzi em Pacientes com Chagas Submetidos ao Transplante Cardíaco
inferred← citeshttps://doi.org/10.36660/abc.20230588iopenalex-snapshot
Absolute Lymphocyte Count: a Predictor of Positive Serum PCR for Trypanosoma cruzi in Patients with Chagas Disease Undergoing Heart Transplantation
inferred← citeshttps://doi.org/10.53730/ijhs.v6ns4.11814openalex-snapshot
Low absolute neutrophilic and lymphocytic counts in children with CMV reactivation following HSCT
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