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Metabolic consequences of knocking outUGT85B1, the gene encoding the glucosyltransferase required for synthesis of dhurrin inSorghum bicolor(L. Moench)
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/9780470015902.a0021537openalex-snapshot
Glycosyltransferases of Small Molecules: Their Roles in Plant Biology
inferredcites →https://doi.org/10.1002/jsfa.5752openalex-snapshot
Drying and processing protocols affect the quantification of cyanogenic glucosides in forage sorghum
inferredcites →https://doi.org/10.1006/abbi.1998.1068openalex-snapshot
Substrate Specificity of the Cytochrome P450 Enzymes CYP79A1 and CYP71E1 Involved in the Biosynthesis of the Cyanogenic Glucoside Dhurrin inSorghum bicolor(L.) Moench
inferredcites →https://doi.org/10.1007/s11248-005-3737-7openalex-snapshot
Consequences of Transferring Three Sorghum Genes for Secondary Metabolite (Cyanogenic Glucoside) Biosynthesis to Grapevine Hairy Roots
inferredcites →https://doi.org/10.1007/s11306-007-0079-xopenalex-snapshot
Lessons learned from metabolic engineering of cyanogenic glucosides
inferredcites →https://doi.org/10.1016/j.pbi.2005.03.014openalex-snapshot
Metabolon formation and metabolic channeling in the biosynthesis of plant natural products
inferredcites →https://doi.org/10.1016/j.pbi.2010.01.009openalex-snapshot
Functional diversifications of cyanogenic glucosides
inferredcites →https://doi.org/10.1016/j.phytochem.2007.06.033openalex-snapshot
Metabolon formation in dhurrin biosynthesis
inferredcites →https://doi.org/10.1016/j.phytochem.2008.04.018openalex-snapshot
Hydroxynitrile glucosides
inferredcites →https://doi.org/10.1016/j.phytochem.2008.12.009openalex-snapshot
Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling
inferredcites →https://doi.org/10.1016/j.phytochem.2009.01.013openalex-snapshot
Substrate specificities of family 1 UGTs gained by domain swapping
inferredcites →https://doi.org/10.1016/j.phytochem.2011.05.001openalex-snapshot
Homology modeling of the three membrane proteins of the dhurrin metabolon: Catalytic sites, membrane surface association and protein–protein interactions
inferredcites →https://doi.org/10.1016/j.phytochem.2011.08.022openalex-snapshot
Phenylalanine derived cyanogenic diglucosides from Eucalyptus camphora and their abundances in relation to ontogeny and tissue type
inferredcites →https://doi.org/10.1016/j.tplants.2012.04.004openalex-snapshot
Why biosynthetic genes for chemical defense compounds cluster
inferredcites →https://doi.org/10.1016/j.tplants.2014.11.002openalex-snapshot
Plasticity of specialized metabolism as mediated by dynamic metabolons
inferredcites →https://doi.org/10.1016/s0021-9258(19)85850-7openalex-snapshot
The biosynthesis of cyanogenic glucosides in higher plants. Channeling of intermediates in dhurrin biosynthesis by a microsomal system from Sorghum bicolor (linn) Moench.
inferredcites →https://doi.org/10.1016/s0031-9422(02)00558-7openalex-snapshot
On the origin of family 1 plant glycosyltransferases
inferredcites →https://doi.org/10.1016/s0031-9422(03)00261-9openalex-snapshot
The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor
inferredcites →https://doi.org/10.1023/a:1005915507497openalex-snapshot
Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin
inferredcites →https://doi.org/10.1042/bj20150390openalex-snapshot
A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species
inferredcites →https://doi.org/10.1046/j.1365-313x.1999.00642.xopenalex-snapshot
Metabolic engineering of p‐hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor
inferredcites →https://doi.org/10.1071/fp07275openalex-snapshot
A seed coat cyanohydrin glucosyltransferase is associated with bitterness in almond (Prunus dulcis) kernels
inferredcites →https://doi.org/10.1071/fp07275_eropenalex-snapshot
Erratum to : A seed coat cyanohydrin glucosyltransferase is associated with bitterness in almond ( Prunus dulcis ) kernels
inferredcites →https://doi.org/10.1073/pnas.0409233102openalex-snapshot
Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome
inferredcites →https://doi.org/10.1073/pnas.0709315104openalex-snapshot
Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism
inferredcites →https://doi.org/10.1074/jbc.270.8.3506openalex-snapshot
Cytochrome P-450TYR Is a Multifunctional Heme-Thiolate Enzyme Catalyzing the Conversion of L-Tyrosine to p-Hydroxyphenylacetaldehyde Oxime in the Biosynthesis of the Cyanogenic Glucoside Dhurrin in Sorghum bicolor (L.) Moench
inferredcites →https://doi.org/10.1074/jbc.274.50.35483openalex-snapshot
The UDP-glucose:p-Hydroxymandelonitrile-O-Glucosyltransferase That Catalyzes the Last Step in Synthesis of the Cyanogenic Glucoside Dhurrin in Sorghum bicolor
inferredcites →https://doi.org/10.1080/00103627509366547openalex-snapshot
Rapid colorimetric determination of nitrate in plant tissue by nitration of salicylic acid
inferredcites →https://doi.org/10.1093/jxb/eru526openalex-snapshot
Utilization of a high-throughput shoot imaging system to examine the dynamic phenotypic responses of a C4 cereal crop plant to nitrogen and water deficiency over time
inferredcites →https://doi.org/10.1104/pp.000687openalex-snapshot
Dhurrin Synthesis in Sorghum Is Regulated at the Transcriptional Level and Induced by Nitrogen Fertilization in Older Plants
inferredcites →https://doi.org/10.1104/pp.105.063842openalex-snapshot
Determination of Catalytic Key Amino Acids and UDP Sugar Donor Specificity of the Cyanohydrin Glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular Modeling Substantiated by Site-Specific Mutagenesis and Biochemical Analyses
inferredcites →https://doi.org/10.1104/pp.115.4.1661openalex-snapshot
Isolation and Reconstitution of Cytochrome P450ox and in Vitro Reconstitution of the Entire Biosynthetic Pathway of the Cyanogenic Glucoside Dhurrin from Sorghum
inferredcites →https://doi.org/10.1104/pp.123.4.1437openalex-snapshot
Transgenic Tobacco and Arabidopsis Plants Expressing the Two Multifunctional Sorghum Cytochrome P450 Enzymes, CYP79A1 and CYP71E1, Are Cyanogenic and Accumulate Metabolites Derived from Intermediates in Dhurrin Biosynthesis
inferredcites →https://doi.org/10.1104/pp.94.3.1219openalex-snapshot
Turnover of Dhurrin in Green Sorghum Seedlings
inferredcites →https://doi.org/10.1105/tpc.109.073502openalex-snapshot
Genetic Screening Identifies Cyanogenesis-Deficient Mutants of Lotus japonicus and Reveals Enzymatic Specificity in Hydroxynitrile Glucoside Metabolism
inferredcites →https://doi.org/10.1111/j.1365-313x.2011.04685.xopenalex-snapshot
Genomic clustering of cyanogenic glucoside biosynthetic genes aids their identification in Lotus japonicus and suggests the repeated evolution of this chemical defence pathway
inferredcites →https://doi.org/10.1111/j.1365-313x.2011.04695.xopenalex-snapshot
Characterization and expression profile of two UDP‐glucosyltransferases, UGT85K4 and UGT85K5, catalyzing the last step in cyanogenic glucoside biosynthesis in cassava
inferredcites →https://doi.org/10.1111/j.1467-7652.2011.00646.xopenalex-snapshot
A combined biochemical screen and TILLING approach identifies mutations in Sorghum bicolor L. Moench resulting in acyanogenic forage production
inferredcites →https://doi.org/10.1111/pce.12209openalex-snapshot
Age versus stage: does ontogeny modify the effect of phosphorus and arbuscular mycorrhizas on above‐ and below‐ground defence in forage sorghum?
inferredcites →https://doi.org/10.1126/science.1062249openalex-snapshot
Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis
inferredcites →https://doi.org/10.1146/annurev-arplant-050213-040027openalex-snapshot
Cyanogenic Glycosides: Synthesis, Physiology, and Phenotypic Plasticity
inferredcites →https://doi.org/10.1371/journal.pone.0015776openalex-snapshot
Engineering Melon Plants with Improved Fruit Shelf Life Using the TILLING Approach
inferredcites →https://doi.org/10.1385/1-59259-413-1:205openalex-snapshot
High-Throughput TILLING for Functional Genomics
inferredcites →https://doi.org/10.3835/plantgenome2014.09.0048openalex-snapshot
Natural Variation in Synthesis and Catabolism Genes Influences Dhurrin Content in Sorghum
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112645zenodo-depositor-declared
Variation in production of cyanogenic glucosides during early plant development: A comparison of wild and domesticated sorghum
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Regulation of Expression of Transcription Factors for Enhanced Secondary Metabolites Production Under Challenging Conditions
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Cloning of Economically Significant Sorghum Mutant Genes
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Sorghum Allelopathy for Weed Control
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LC–MS based metabolic fingerprinting of apricot pistils after self-compatible and self-incompatible pollinations
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OsSGT1 Is a Glucosyltransferase Gene Involved in the Glucose Conjugation of Phenolics in Rice
inferred← citeshttps://doi.org/10.1007/s11816-024-00886-5openalex-snapshot
Identification and expression profile of dhurrin biosynthesis pathway genes in sorghum vegetative tissues
inferred← citeshttps://doi.org/10.1016/b978-0-443-26614-0.00009-6openalex-snapshot
Genome engineering in sorghum
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The production of plant natural products beneficial to humanity by metabolic engineering
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Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent
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Species-specific dynamics of specialized metabolism in germinating sorghum grain revealed by temporal and tissue-resolved transcriptomics and metabolomics
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Elucidation of the Amygdalin Pathway Reveals the Metabolic Basis of Bitter and Sweet Almonds (Prunus dulcis)
inferred← citeshttps://doi.org/10.1104/pp.19.01357openalex-snapshot
Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination
inferred← citeshttps://doi.org/10.1111/nph.15184openalex-snapshot
Micro‐ and macroevolutionary adaptation through repeated loss of a complete metabolic pathway
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UGT709G1: a novel uridine diphosphate glycosyltransferase involved in the biosynthesis of picrocrocin, the precursor of safranal in saffron (Crocus sativus)
inferred← citeshttps://doi.org/10.1111/pbi.70746openalex-snapshot
Targeted Knockout of CYP79A1 Reduces Cyanogenic Potential in Grain Sorghum
inferred← citeshttps://doi.org/10.1111/pce.15536openalex-snapshot
Drought‐Induced Cyanogenesis in Sorghum ( Sorghum bicolor L.): Genotypic Variation in Dhurrin Biosynthesis and Stress Response
inferred← citeshttps://doi.org/10.1111/pce.70244openalex-snapshot
Genotype‐Specific Regulation of Dhurrin Metabolism Under Drought Stress in Sorghum
inferred← citeshttps://doi.org/10.1111/plb.13522openalex-snapshot
Wounding and methyl jasmonate increase cyanogenic glucoside concentrations in Sorghum bicolor via upregulation of biosynthesis
inferred← citeshttps://doi.org/10.1111/tpj.13923openalex-snapshot
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inferred← citeshttps://doi.org/10.1111/tpj.14113openalex-snapshot
Genetic and genomic resources of sorghum to connect genotype with phenotype in contrasting environments
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Controlled hydroxylations of diterpenoids allow for plant chemical defense without autotoxicity
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Fine mapping of a major QTL qPA7-1 for low hydrocyanic acid content in sorghum–sudangrass hybrid
inferred← citeshttps://doi.org/10.1186/s12864-016-3360-4openalex-snapshot
Dhurrin metabolism in the developing grain of Sorghum bicolor (L.) Moench investigated by metabolite profiling and novel clustering analyses of time-resolved transcriptomic data
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Transient expression of SbDhr2 and MeHNL in Gossypium hirsutum for herbivore deterrence assay with Spodoptera litura
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Biosynthesis, regulation, and significance of cyanogenic glucosides
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Transcriptome Profiling and Genome-Wide Association Studies Reveal GSTs and Other Defense Genes Involved in Multiple Signaling Pathways Induced by Herbicide Safener in Grain Sorghum
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Plant Desiccation Tolerance and its Regulation in the Foliage of Resurrection “Flowering-Plant” Species
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The Putative GATA Transcription Factor SbGATA22 as a Novel Regulator of Dhurrin Biosynthesis
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Unveiling the Potential Role of Dhurrin in Sorghum During Infection by the Head Smut Pathogen Sporisorium reilianum f. sp. reilianum
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Allocation of Resources to Cyanogenic Glucosides Does Not Incur a Growth Sacrifice in Sorghum bicolor (L.) Moench
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Biosynthesis and Role of Dhurrin in Forage Sorghum
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