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Amotivation in Schizophrenia: Integrated Assessment With Behavioral, Clinical, and Imaging Measures

https://doi.org/10.1093/schbul/sbu026
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Increased Synaptic Dopamine Function in Associative Regions of the Striatum in Schizophrenia
inferredcites →https://doi.org/10.1001/archgenpsychiatry.2011.1269openalex-snapshot
Negative Symptoms and the Failure to Represent the Expected Reward Value of Actions
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Improvement of Brain Reward Abnormalities by Antipsychotic Monotherapy in Schizophrenia
inferredcites →https://doi.org/10.1007/s00213-006-0405-4openalex-snapshot
Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
inferredcites →https://doi.org/10.1007/s00213-007-1016-4openalex-snapshot
Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine
inferredcites →https://doi.org/10.1007/s00213-009-1586-4openalex-snapshot
Altered reward functions in patients on atypical antipsychotic medication in line with the revised dopamine hypothesis of schizophrenia
inferredcites →https://doi.org/10.1007/s002130050566openalex-snapshot
"Depression" increases "craving" for sweet rewards in animal and human models of depression and craving
inferredcites →https://doi.org/10.1007/s002130051031openalex-snapshot
Effects of response requirement and the availability of an alternative reinforcer on cigarette smoking by schizophrenics
inferredcites →https://doi.org/10.1007/s10648-009-9107-xopenalex-snapshot
A Review of Self-Report and Alternative Approaches in the Measurement of Student Motivation
inferredcites →https://doi.org/10.1007/s11682-008-9022-7openalex-snapshot
Auditory Oddball fMRI in Schizophrenia: Association of Negative Symptoms with Regional Hypoactivation to Novel Distractors
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Anhedonia in schizophrenia
inferredcites →https://doi.org/10.1007/s11920-010-0148-0openalex-snapshot
Assessment of Pharmacotherapy for Negative Symptoms of Schizophrenia
inferredcites →https://doi.org/10.1016/j.biopsych.2008.12.016openalex-snapshot
Reward Feedback Alterations in Unmedicated Schizophrenia Patients: Relevance for Delusions
inferredcites →https://doi.org/10.1016/j.biopsych.2009.10.020openalex-snapshot
Anhedonia and Emotional Experience in Schizophrenia: Neural and Behavioral Indicators
inferredcites →https://doi.org/10.1016/j.biopsych.2011.01.012openalex-snapshot
Pharmacologic Rescue of Motivational Deficit in an Animal Model of the Negative Symptoms of Schizophrenia
inferredcites →https://doi.org/10.1016/j.biopsych.2012.02.007openalex-snapshot
Alterations of the Brain Reward System in Antipsychotic Naïve Schizophrenia Patients
inferredcites →https://doi.org/10.1016/j.biopsych.2012.12.022openalex-snapshot
Negative Symptoms of Schizophrenia Are Associated with Abnormal Effort-Cost Computations
inferredcites →https://doi.org/10.1016/j.jpsychires.2013.08.003openalex-snapshot
Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost-benefit decision-making
inferredcites →https://doi.org/10.1016/j.neubiorev.2010.06.006openalex-snapshot
Reconsidering anhedonia in depression: Lessons from translational neuroscience
inferredcites →https://doi.org/10.1016/j.neuroimage.2005.07.051openalex-snapshot
Dysfunction of ventral striatal reward prediction in schizophrenia
inferredcites →https://doi.org/10.1016/j.neuroimage.2009.12.031openalex-snapshot
Altered activation in association with reward-related trial-and-error learning in patients with schizophrenia
inferredcites →https://doi.org/10.1016/j.neuroscience.2004.07.011openalex-snapshot
Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat
inferredcites →https://doi.org/10.1016/j.psychres.2008.04.016openalex-snapshot
The role of effort, cognitive expectancy appraisals and coping style in the maintenance of the negative symptoms of schizophrenia
inferredcites →https://doi.org/10.1016/j.schres.2009.08.015openalex-snapshot
Motivation and its Relationship to Neurocognition, Social Cognition, and Functional Outcome in Schizophrenia
inferredcites →https://doi.org/10.1016/j.schres.2009.11.007openalex-snapshot
Neural correlates of reward processing in schizophrenia — Relationship to apathy and depression
inferredcites →https://doi.org/10.1016/j.schres.2011.06.030openalex-snapshot
Development and psychometric validation of the Clinical Assessment Interview for Negative Symptoms (CAINS)
inferredcites →https://doi.org/10.1016/j.schres.2012.02.018openalex-snapshot
Behavioral validation of avolition in schizophrenia
inferredcites →https://doi.org/10.1016/j.tins.2011.11.005openalex-snapshot
The neurobiology of anhedonia and other reward-related deficits
inferredcites →https://doi.org/10.1037//1064-1297.7.4.347openalex-snapshot
Effects of abstinence on cigarette smoking among outpatients with schizophrenia.
inferredcites →https://doi.org/10.1037/a0013657openalex-snapshot
Reinforcing effects of stimulants in humans: Sensitivity of progressive-ratio schedules.
inferredcites →https://doi.org/10.1038/mp.2011.75openalex-snapshot
Disambiguating ventral striatum fMRI-related bold signal during reward prediction in schizophrenia
inferredcites →https://doi.org/10.1038/npp.2008.214openalex-snapshot
Patients with Schizophrenia have a Reduced Neural Response to Both Unpredictable and Predictable Primary Reinforcers
inferredcites →https://doi.org/10.1038/npp.2010.126openalex-snapshot
Abnormal Responses to Monetary Outcomes in Cortex, but not in the Basal Ganglia, in Schizophrenia
inferredcites →https://doi.org/10.1038/npp.2012.15openalex-snapshot
Dissociation of Hedonic Reaction to Reward and Incentive Motivation in an Animal Model of the Negative Symptoms of Schizophrenia
inferredcites →https://doi.org/10.1038/sj.mp.4002058openalex-snapshot
Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
inferredcites →https://doi.org/10.1038/sj.npp.1300225openalex-snapshot
Chronic Pubertal, but not Adult Chronic Cannabinoid Treatment Impairs Sensorimotor Gating, Recognition Memory, and the Performance in a Progressive Ratio Task in Adult Rats
inferredcites →https://doi.org/10.1038/sj.npp.1301620openalex-snapshot
Abnormal Reward System Activation in Mania
inferredcites →https://doi.org/10.1055/s-2007-984463openalex-snapshot
The Influence of Antipsychotic Treatment on Brain Reward System Reactivity in Schizophrenia Patients
inferredcites →https://doi.org/10.1080/105504900750047355openalex-snapshot
What We Have Learned about Addiction from Animal Models of Drug Self‐Administration
inferredcites →https://doi.org/10.1093/brain/awr059openalex-snapshot
Expected value and prediction error abnormalities in depression and schizophrenia
inferredcites →https://doi.org/10.1093/schbul/sbj053openalex-snapshot
The NIMH-MATRICS Consensus Statement on Negative Symptoms
inferredcites →https://doi.org/10.1093/schbul/sbn008openalex-snapshot
Defeatist Beliefs as a Mediator of Cognitive Impairment, Negative Symptoms, and Functioning in Schizophrenia
inferredcites →https://doi.org/10.1093/schbul/sbn061openalex-snapshot
Emotional Experience in Patients With Schizophrenia Revisited: Meta-analysis of Laboratory Studies
inferredcites →https://doi.org/10.1093/schbul/sbn094openalex-snapshot
Negative Symptoms in Schizophrenia: Avolition and Occam's Razor
inferredcites →https://doi.org/10.1093/schbul/sbn157openalex-snapshot
CNTRICS Final Task Selection: Social Cognitive and Affective Neuroscience-Based Measures
inferredcites →https://doi.org/10.1093/schbul/sbp125openalex-snapshot
Mutant Mouse Models: Genotype-Phenotype Relationships to Negative Symptoms in Schizophrenia
inferredcites →https://doi.org/10.1093/schbul/sbq068openalex-snapshot
Goal Representations and Motivational Drive in Schizophrenia: The Role of Prefrontal-Striatal Interactions
inferredcites →https://doi.org/10.1111/j.1745-6924.2009.01125.xopenalex-snapshot
Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition
inferredcites →https://doi.org/10.1126/science.134.3483.943openalex-snapshot
Progressive Ratio as a Measure of Reward Strength
inferredcites →https://doi.org/10.1152/jn.00027.2010openalex-snapshot
Choosing to Make an Effort: The Role of Striatum in Signaling Physical Effort of a Chosen Action
inferredcites →https://doi.org/10.1152/jn.00870.2009openalex-snapshot
Rewarding Feedback After Correct Visual Discriminations Has Both General and Specific Influences on Visual Cortex
inferredcites →https://doi.org/10.1152/jn.2000.84.6.3072openalex-snapshot
Tracking the Hemodynamic Responses to Reward and Punishment in the Striatum
inferredcites →https://doi.org/10.1176/appi.ajp.163.3.488openalex-snapshot
Negative Signs and Symptoms Secondary to Antipsychotics: A Double-Blind, Randomized Trial of a Single Dose of Placebo, Haloperidol, and Risperidone in Healthy Volunteers
inferredcites →https://doi.org/10.1176/appi.ajp.2010.09091379openalex-snapshot
Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders
inferredcites →https://doi.org/10.1176/appi.ajp.2012.12010109openalex-snapshot
The Clinical Assessment Interview for Negative Symptoms (CAINS): Final Development and Validation
inferredcites →https://doi.org/10.1177/1073858404263526openalex-snapshot
The Neural Substrates of Reward Processing in Humans: The Modern Role of fMRI
inferredcites →https://doi.org/10.1371/journal.pone.0035622openalex-snapshot
Pavlovian Reward Prediction and Receipt in Schizophrenia: Relationship to Anhedonia
inferredcites →https://doi.org/10.1371/journal.pone.0047934openalex-snapshot
Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences
inferredcites →https://doi.org/10.1523/jneurosci.0642-05.2005openalex-snapshot
Distributed Neural Representation of Expected Value
inferredcites →https://doi.org/10.1523/jneurosci.0895-11.2011openalex-snapshot
Dorsolateral Prefrontal Cortex Drives Mesolimbic Dopaminergic Regions to Initiate Motivated Behavior
inferredcites →https://doi.org/10.1523/jneurosci.3446-06.2006openalex-snapshot
Preference for Immediate over Delayed Rewards Is Associated with Magnitude of Ventral Striatal Activity
inferredcites →https://doi.org/10.1523/jneurosci.4341-08.2009openalex-snapshot
Neural Correlates of Probabilistic Category Learning in Patients with Schizophrenia
inferredcites →https://doi.org/10.1523/jneurosci.4515-08.2009openalex-snapshot
Effort-Based Cost–Benefit Valuation and the Human Brain
inferredcites →https://doi.org/10.1901/jeab.2012.97-125openalex-snapshot
THE BEHAVIORAL PHARMACOLOGY OF EFFORT‐RELATED CHOICE BEHAVIOR: DOPAMINE, ADENOSINE AND BEYOND
inferredcites →https://doi.org/10.3389/fnbeh.2011.00081openalex-snapshot
Striatal intrinsic reinforcement signals during recognition memory: relationship to response bias and dysregulation in schizophrenia
inferredcites →https://doi.org/10.3389/fnhum.2012.00136openalex-snapshot
Neurobiology of Schizophrenia: Search for the Elusive Correlation with Symptoms

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Intact Ventral Striatal Prediction Error Signaling in Medicated Schizophrenia Patients
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Avolition in schizophrenia is associated with reduced willingness to expend effort for reward on a Progressive Ratio task
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inferred← citeshttps://doi.org/10.1016/j.schres.2018.10.012openalex-snapshot
Goal-directed planning and action impairments in schizophrenia evaluated in a virtual environment
inferred← citeshttps://doi.org/10.1016/j.schres.2018.10.026openalex-snapshot
Psychotic like experiences as part of a continuum of psychosis: Associations with effort-based decision-making and reward responsivity
inferred← citeshttps://doi.org/10.1016/j.schres.2020.08.018openalex-snapshot
Apathy is not associated with reduced ventral striatal volume in patients with schizophrenia
inferred← citeshttps://doi.org/10.1016/j.schres.2021.08.007openalex-snapshot
How far to go in deconstructing negative symptoms? Behavioural and neural level evidence for the amotivation domain
inferred← citeshttps://doi.org/10.1016/j.schres.2023.09.035openalex-snapshot
The role of defeatist performance beliefs on cognitive effort-cost decision-making in schizophrenia
inferred← citeshttps://doi.org/10.1016/j.schres.2026.04.004openalex-snapshot
Impaired intrinsic motivation in psychosis risk relates to ventral striatum activation to self-generated reinforcement signals
inferred← citeshttps://doi.org/10.1016/j.scog.2024.100325openalex-snapshot
Abnormal hedonic process in patients with stable schizophrenia: Relationships to negative symptoms and social functioning
inferred← citeshttps://doi.org/10.1016/j.ynstr.2025.100724openalex-snapshot
An inverted U-shaped relationship between chronic stress and the motivation to expend effort for reward
inferred← citeshttps://doi.org/10.1017/s0033291717002525openalex-snapshot
Effort-cost decision-making in psychosis and depression: could a similar behavioral deficit arise from disparate psychological and neural mechanisms?
inferred← citeshttps://doi.org/10.1017/s0033291719000801openalex-snapshot
Shared and dissociable features of apathy and reward system dysfunction in bipolar I disorder and schizophrenia
inferred← citeshttps://doi.org/10.1017/s0033291719002769openalex-snapshot
Abnormal cognitive effort allocation and its association with amotivation in first-episode psychosis
inferred← citeshttps://doi.org/10.1017/s0033291720000264openalex-snapshot
Aberrant salience and reward processing: a comparison of measures in schizophrenia and anxiety
inferred← citeshttps://doi.org/10.1017/s003329172100204xopenalex-snapshot
Reduced willingness to expend effort for rewards is associated with risk for conversion and negative symptom severity in youth at clinical high-risk for psychosis
inferred← citeshttps://doi.org/10.1017/s0033291723000521openalex-snapshot
Do the negative symptoms of schizophrenia reflect reduced responsiveness to reward? Examination using a reward prediction error (RPE) task
inferred← citeshttps://doi.org/10.1017/s0033291724003416openalex-snapshot
Probabalistic reinforcement learning impairments predict negative symptom severity and risk for conversion in youth at clinical high-risk for psychosis
inferred← citeshttps://doi.org/10.1037/abn0000153openalex-snapshot
Negative symptoms are associated with an increased subjective cost of cognitive effort.
inferred← citeshttps://doi.org/10.1037/abn0000443openalex-snapshot
Effortful goal-directed behavior in schizophrenia: Computational subtypes and associations with cognition.
inferred← citeshttps://doi.org/10.1038/npjschz.2015.20openalex-snapshot
Anhedonia in the psychosis risk syndrome: associations with social impairment and basal orbitofrontal cortical activity
inferred← citeshttps://doi.org/10.1038/npp.2015.120openalex-snapshot
GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders
inferred← citeshttps://doi.org/10.1038/npp.2015.3openalex-snapshot
Antipsychotics and Amotivation
inferred← citeshttps://doi.org/10.1038/npp.2015.75openalex-snapshot
Common and Dissociable Dysfunction of the Reward System in Bipolar and Unipolar Depression
inferred← citeshttps://doi.org/10.1038/npp.2016.143openalex-snapshot
Inflammation Effects on Motivation and Motor Activity: Role of Dopamine
inferred← citeshttps://doi.org/10.1038/s41380-018-0206-2openalex-snapshot
Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators
inferred← citeshttps://doi.org/10.1038/s41380-021-01320-wopenalex-snapshot
Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia
inferred← citeshttps://doi.org/10.1038/s41386-025-02114-2openalex-snapshot
Inflammation is associated with avolition and reduced resting state functional connectivity in corticostriatal reward circuitry in patients with schizophrenia
inferred← citeshttps://doi.org/10.1038/s41398-021-01562-wopenalex-snapshot
Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms
inferred← citeshttps://doi.org/10.1038/s41398-021-01589-zopenalex-snapshot
Differential dopamine release by psychosis-generating and non-psychosis-generating addictive substances in the nucleus accumbens and dorsomedial striatum
inferred← citeshttps://doi.org/10.1038/s41537-021-00178-9openalex-snapshot
Relationship of ventral striatum activation during effort discounting to clinical amotivation severity in schizophrenia
inferred← citeshttps://doi.org/10.1038/s41537-022-00294-0openalex-snapshot
Behavioural phenotypes of intrinsic motivation in schizophrenia determined by cluster analysis of objectively quantified real-world performance
inferred← citeshttps://doi.org/10.1038/s41598-017-03564-5openalex-snapshot
Neural basis of self-initiative in relation to apathy in a student sample
inferred← citeshttps://doi.org/10.1038/s41598-018-37802-1openalex-snapshot
The transdiagnostic structure of mental effort avoidance
inferred← citeshttps://doi.org/10.1038/s41598-020-66873-2openalex-snapshot
Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression
inferred← citeshttps://doi.org/10.1073/pnas.2221510120openalex-snapshot
Effort Foraging Task reveals positive correlation between individual differences in the cost of cognitive and physical effort in humans
inferred← citeshttps://doi.org/10.1080/13546805.2014.993463openalex-snapshot
Effort discounting and its association with negative symptoms in schizophrenia
inferred← citeshttps://doi.org/10.1080/13803395.2016.1184232openalex-snapshot
Computerized assessment of goal-directed behavior in Parkinson’s disease
inferred← citeshttps://doi.org/10.1093/brain/awaa025openalex-snapshot
Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning
inferred← citeshttps://doi.org/10.1093/brain/aww050openalex-snapshot
Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
inferred← citeshttps://doi.org/10.1093/brain/awx278openalex-snapshot
Why not try harder? Computational approach to motivation deficits in neuro-psychiatric diseases
inferred← citeshttps://doi.org/10.1093/jpe/rtaf079openalex-snapshot
Contrasting responses of plant and soil microbial diversity to altered phosphorus supply
inferred← citeshttps://doi.org/10.1093/med/9780190681425.003.0016openalex-snapshot
Cognitive and Motivational Neuroscience of Psychotic Disorders
inferred← citeshttps://doi.org/10.1093/schbul/sbaa169openalex-snapshot
Orbitofrontal-Striatal Structural Alterations Linked to Negative Symptoms at Different Stages of the Schizophrenia Spectrum
inferred← citeshttps://doi.org/10.1093/schbul/sbac076openalex-snapshot
Preserved Unconscious Processing in Schizophrenia: The Case of Motivation
inferred← citeshttps://doi.org/10.1093/schbul/sbae046openalex-snapshot
Striatal Response to Reward Anticipation as a Biomarker for Schizophrenia and Negative Symptoms: Effects, Test-Retest Reliability, and Stability Across Sites
inferred← citeshttps://doi.org/10.1093/schbul/sbae162openalex-snapshot
Increased Sensitivity to Effort and Perception of Effort in People with Schizophrenia
inferred← citeshttps://doi.org/10.1093/schbul/sbaf078openalex-snapshot
Orbitofrontal Thickness and Network Associations as Transdiagnostic Signature of Amotivation Along the Bipolar-Schizophrenia Spectrum
inferred← citeshttps://doi.org/10.1093/schbul/sbaf252openalex-snapshot
Effort Aversion and Reward Sensitivity in Schizophrenia: Computational Phenotyping of Motivational Deficits across Behavioral Tasks
inferred← citeshttps://doi.org/10.1093/schbul/sbv071openalex-snapshot
Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia:
inferred← citeshttps://doi.org/10.1093/schbul/sbv089openalex-snapshot
Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 1—Psychometric Characteristics of 5 Paradigms
inferred← citeshttps://doi.org/10.1093/schbul/sbv090openalex-snapshot
Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 2—External Validity and Correlates
inferred← citeshttps://doi.org/10.1093/schbul/sbv093openalex-snapshot
Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia
inferred← citeshttps://doi.org/10.1093/schbul/sbv226openalex-snapshot
Probabilistic Reversal Learning in Schizophrenia: Stability of Deficits and Potential Causal Mechanisms
inferred← citeshttps://doi.org/10.1093/schbul/sbw046openalex-snapshot
A Psychometric Comparison of the Clinical Assessment Interview for Negative Symptoms and the Brief Negative Symptom Scale
inferred← citeshttps://doi.org/10.1093/schbul/sbw142openalex-snapshot
Ventral Striatal Dysfunction and Symptom Expression in Individuals With Schizotypal Personality Traits and Early Psychosis
inferred← citeshttps://doi.org/10.1093/schbul/sbx063openalex-snapshot
Paradigms for Assessing Hedonic Processing and Motivation in Humans: Relevance to Understanding Negative Symptoms in Psychopathology
inferred← citeshttps://doi.org/10.1093/schbul/sbx065openalex-snapshot
Preclinical Models to Investigate Mechanisms of Negative Symptoms in Schizophrenia
inferred← citeshttps://doi.org/10.1093/schbul/sbx137openalex-snapshot
Multisite Machine Learning Analysis Provides a Robust Structural Imaging Signature of Schizophrenia Detectable Across Diverse Patient Populations and Within Individuals
inferred← citeshttps://doi.org/10.1093/schbul/sby013openalex-snapshot
Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective
inferred← citeshttps://doi.org/10.1093/schbul/sby109openalex-snapshot
Reduced Neural Sensitivity to Social vs Nonsocial Reward in Schizophrenia
inferred← citeshttps://doi.org/10.1093/schizbullopen/sgae024openalex-snapshot
Negative Symptoms and Their Associations With Other Clinical Variables and Working Memory Across the Schizophrenia Spectrum and Bipolar Disorder
inferred← citeshttps://doi.org/10.1097/hrp.0000000000000326openalex-snapshot
Brick by Brick: Building a Transdiagnostic Understanding of Inflammation in Psychiatry
inferred← citeshttps://doi.org/10.1101/2020.12.01.407197openalex-snapshot
Decision value signals in the ventromedial prefrontal cortex and motivational and hedonic symptoms across mood and psychotic disorders
inferred← citeshttps://doi.org/10.1101/2024.07.29.24311172openalex-snapshot
Orbitofrontal thickness and network associations as transdiagnostic signature of negative symptoms along the bipolar-schizophrenia spectrum
inferred← citeshttps://doi.org/10.1101/2025.01.23.634295openalex-snapshot
A systematic review and ALE meta-analysis of cognitive control, motivation and effort-based decision-making in schizophrenia and mood disorders: Implications for multidimensional apathy
inferred← citeshttps://doi.org/10.1111/ejn.14150openalex-snapshot
Oxygen responses within the nucleus accumbens are associated with individual differences in effort exertion in rats
inferred← citeshttps://doi.org/10.1111/gbb.12710openalex-snapshot
Impaired working memory, cognitive flexibility and reward processing in mice genetically lacking Gpr88: Evidence for a key role for Gpr88 in multiple cortico‐striatal‐thalamic circuits
inferred← citeshttps://doi.org/10.1111/jnc.16243openalex-snapshot
Cross‐species translational paradigms for assessing positive valence system as defined by the RDoC matrix
inferred← citeshttps://doi.org/10.1111/jnp.12399openalex-snapshot
Non‐optimal cognitive offloading in schizophrenia in a prospective memory task: Influence of both metacognitive beliefs and cognitive effort avoidance
inferred← citeshttps://doi.org/10.1136/bmjopen-2022-070654openalex-snapshot
Suicidal thoughts and behaviours among military veterans: protocol for a prospective, observational, neuroimaging study
inferred← citeshttps://doi.org/10.1176/appi.ajp.2016.16070774openalex-snapshot
Common Dimensional Reward Deficits Across Mood and Psychotic Disorders: A Connectome-Wide Association Study
inferred← citeshttps://doi.org/10.1177/0269881117731162openalex-snapshot
Blockade of dopamine D 1 -family receptors attenuates the mania-like hyperactive, risk-preferring, and high motivation behavioral profile of mice with low dopamine transporter levels
inferred← citeshttps://doi.org/10.1177/0269881119896043openalex-snapshot
Investigating serotonergic contributions to cognitive effort allocation, attention, and impulsive action in female rats
inferred← citeshttps://doi.org/10.1177/2167702620901558openalex-snapshot
Effort, Avolition, and Motivational Experience in Schizophrenia: Analysis of Behavioral and Neuroimaging Data With Relationships to Daily Motivational Experience
inferred← citeshttps://doi.org/10.1177/21677026211004543openalex-snapshot
Dynamic Attention Regulation for Prospective Goals in Schizophrenia
inferred← citeshttps://doi.org/10.1371/journal.pone.0198215openalex-snapshot
Investigating the association of ventral and dorsal striatal dysfunction during reward anticipation with negative symptoms in patients with schizophrenia and healthy individuals
inferred← citeshttps://doi.org/10.1503/jpn.140383openalex-snapshot
Ventral striatal hypoactivation is associated with apathy but not diminished expression in patients with schizophrenia
inferred← citeshttps://doi.org/10.1503/jpn.150381openalex-snapshot
Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice
inferred← citeshttps://doi.org/10.1515/revneuro-2017-0091openalex-snapshot
Dopamine dysregulation hypothesis: the common basis for motivational anhedonia in major depressive disorder and schizophrenia?
inferred← citeshttps://doi.org/10.1515/revneuro-2026-0030openalex-snapshot
Behavioral, neural and neurochemical basis of effort-related decision making
inferred← citeshttps://doi.org/10.1523/jneurosci.0982-23.2023openalex-snapshot
Amphetamines Improve the Motivation to Invest Effort in Attention-Deficit/Hyperactivity Disorder
inferred← citeshttps://doi.org/10.1891/0889-8391.32.3.203openalex-snapshot
Identifying the “Therapy Targets” for Treating the Negative Symptoms of Psychosis Using Cognitive Behavioral Therapy
inferred← citeshttps://doi.org/10.2174/1570159x13666150612230333openalex-snapshot
Neural Basis of Anhedonia and Amotivation in Patients with Schizophrenia: The Role of Reward System
inferred← citeshttps://doi.org/10.24602/sjpr.62.1_88openalex-snapshot
Computational approach to depression: From the viewpoint of reinforcement learning
inferred← citeshttps://doi.org/10.24902/r.riase.2015.1(1).89openalex-snapshot
Envelhecer com Esquizofrenia
inferred← citeshttps://doi.org/10.31363/2313-7053-2025-2-1011openalex-snapshot
Features of sign-symbolic mediation of concepts in patients with schizophrenia in the presence or absence of a motive of social significance (pilot study)
inferred← citeshttps://doi.org/10.32598/irj.16.3.297openalex-snapshot
Participation of People With Schizophrenia in Everyday Life: Family’s Perspective
inferred← citeshttps://doi.org/10.33612/diss.219070985openalex-snapshot
Dysfunction of the motivational brain
inferred← citeshttps://doi.org/10.3389/fnbeh.2022.827260openalex-snapshot
Psychological Dimensions Relevant to Motivation and Pleasure in Schizophrenia
inferred← citeshttps://doi.org/10.3389/fneur.2019.00858openalex-snapshot
A Touchscreen Motivation Assessment Evaluated in Huntington's Disease Patients and R6/1 Model Mice
inferred← citeshttps://doi.org/10.3389/fpsyg.2020.01469openalex-snapshot
Objective Versus Subjective Effort in Schizophrenia
inferred← citeshttps://doi.org/10.3389/fpsyt.2017.00177openalex-snapshot
Pharmacological Augmentation of Psychosocial and Remediation Training Efforts in Schizophrenia
inferred← citeshttps://doi.org/10.3389/fpsyt.2020.00046openalex-snapshot
Inflammation and Negative Symptoms of Schizophrenia: Implications for Reward Processing and Motivational Deficits
inferred← citeshttps://doi.org/10.3389/fpsyt.2024.1458624openalex-snapshot
Illness-related variables and abnormalities of resting-state brain activity in schizophrenia
inferred← citeshttps://doi.org/10.3390/brainsci10050283openalex-snapshot
Event-Related Potentials (ERP) Indices of Motivation during the Effort Expenditure for Reward Task
inferred← citeshttps://doi.org/10.3390/brainsci13010083openalex-snapshot
Resting-State Brain Activity Dysfunctions in Schizophrenia and Their Associations with Negative Symptom Domains: An fMRI Study
inferred← citeshttps://doi.org/10.3390/healthcare13151796openalex-snapshot
Anhedonia and Negative Symptoms in First-Episode Psychosis: A Systematic Review and Meta-Analysis of Prevalence, Mechanisms, and Clinical Implications
inferred← citeshttps://doi.org/10.3390/ijms24044088openalex-snapshot
Integrative Roles of Dopamine Pathway and Calcium Channels Reveal a Link between Schizophrenia and Opioid Use Disorder
inferred← citeshttps://doi.org/10.3390/jcm11175060openalex-snapshot
Impaired Effort Allocation in Patients with Recent-Onset Schizophrenia and Its Relevance to Negative Symptoms Assessments and Persistent Negative Symptoms
inferred← citeshttps://doi.org/10.3390/nu14235012openalex-snapshot
Halting the Metabolic Complications of Antipsychotic Medication in Patients with a First Episode of Psychosis: How Far Can We Go with the Mediterranean Diet? A Pilot Study
inferred← citeshttps://doi.org/10.3758/s13415-023-01150-zopenalex-snapshot
Amphetamine increases motivation of humans and mice as measured by breakpoint, but does not affect an Electroencephalographic biomarker
inferred← citeshttps://doi.org/10.3758/s13415-025-01353-6openalex-snapshot
Shared and distinct features of common effort-based decision-making paradigms and their relation to brain structure and neuropsychiatric conditions: An integrated narrative review
inferred← citeshttps://doi.org/10.48550/arxiv.2308.03175openalex-snapshot
Adapting Machine Learning Diagnostic Models to New Populations Using a Small Amount of Data: Results from Clinical Neuroscience
inferred← citeshttps://doi.org/10.5334/cpsy.71openalex-snapshot
The Reward-Complexity Trade-off in Schizophrenia
inferred← citeshttps://doi.org/10.5334/hpb.10openalex-snapshot
More Harm than Good? A Pilot of a Motivational Interviewing Based Intervention for Increasing Readiness to Improve Nutrition in Young People Experiencing a First Episode of Psychosis
inferred← citeshttps://doi.org/10.70675/0d7955a2za2d9z49e3z9613z2271f5ed839aopenalex-snapshot
Vulnérabilité du réseau neuronal du noyau accumbens à la déficience développementale en acides gras polyinsaturés n-3 : conséquences sur le système de récompense et de motivation
inferred← citeshttps://doi.org/10.70675/43b0f664ze3e9z438eza225zb06ccd201945openalex-snapshot
Caractérisation neuro-computationnelle des troubles de la motivation dans la dépression : vers une médecine personnalisée en psychiatrie
inferred← citeshttps://doi.org/10.7554/elife.96803openalex-snapshot
A common alteration in effort-based decision-making in apathy, anhedonia, and late circadian rhythm
inferred← citeshttps://doi.org/10.7554/elife.96803.1openalex-snapshot
Overlapping effects of neuropsychiatric symptoms and circadian rhythm on effort-based decision-making
inferred← citeshttps://doi.org/10.7554/elife.96803.2openalex-snapshot
Both neuropsychiatric symptoms and circadian rhythm alter effort-based decision-making
inferred← citeshttps://doi.org/10.7554/elife.96803.3openalex-snapshot
A common alteration in effort-based decision-making in apathy, anhedonia, and late circadian rhythm
inferred← citeshttps://doi.org/10.7554/elife.96803.4openalex-snapshot
A common alteration in effort-based decision-making in apathy, anhedonia, and late circadian rhythm
inferred← citeshttps://doi.org/10.7916/d89z94qzopenalex-snapshot
The role of basal ganglia circuitry in motivation
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