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Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00125-007-0818-6openalex-snapshot

Strong association between mitochondrial DNA copy number and lipogenesis in human white adipose tissue

inferredcites →https://doi.org/10.1016/j.amjcard.2013.05.036openalex-snapshot

Cardiac Steatosis and Left Ventricular Hypertrophy in Patients With Generalized Lipodystrophy as Determined by Magnetic Resonance Spectroscopy and Imaging

inferredcites →https://doi.org/10.1016/j.bbabio.2004.10.003openalex-snapshot

The transcription machinery in mammalian mitochondria

inferredcites →https://doi.org/10.1016/j.bbagrm.2012.03.002openalex-snapshot

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

inferredcites →https://doi.org/10.1016/j.beem.2010.12.001openalex-snapshot

Adipose tissue biology and HIV-infection

inferredcites →https://doi.org/10.1016/j.biocel.2012.09.019openalex-snapshot

Insulin resistance and mitochondrial function in skeletal muscle

inferredcites →https://doi.org/10.1016/j.cell.2008.06.016openalex-snapshot

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

inferredcites →https://doi.org/10.1016/j.cmet.2012.07.017openalex-snapshot

Role of MicroRNA Processing in Adipose Tissue in Stress Defense and Longevity

inferredcites →https://doi.org/10.1016/j.cmet.2012.10.016openalex-snapshot

Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance

inferredcites →https://doi.org/10.1016/j.ecl.2004.03.003openalex-snapshot

Lipodystrophies: rare disorders causing metabolic syndrome

inferredcites →https://doi.org/10.1016/j.mce.2007.09.012openalex-snapshot

Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP/F-1 mice

inferredcites →https://doi.org/10.1016/j.mito.2006.11.017openalex-snapshot

Mitochondrial transcription factor A (TFAM): Roles in maintenance of mtDNA and cellular functions

inferredcites →https://doi.org/10.1016/j.molmet.2013.04.001openalex-snapshot

Adiponectin, driver or passenger on the road to insulin sensitivity?

inferredcites →https://doi.org/10.1016/j.tem.2012.06.004openalex-snapshot

Mitochondrial dysfunction in white adipose tissue

inferredcites →https://doi.org/10.1016/j.tibs.2007.01.003openalex-snapshot

Mitochondrial transcription and its regulation in mammalian cells

inferredcites →https://doi.org/10.1016/j.tips.2011.07.007openalex-snapshot

Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition

inferredcites →https://doi.org/10.1016/j.yjmcc.2009.07.004openalex-snapshot

Ventricular remodeling and function: Insights using murine echocardiography

inferredcites →https://doi.org/10.1016/s0140-6736(05)67483-1openalex-snapshot

Obesity

inferredcites →https://doi.org/10.1038/ki.2010.391openalex-snapshot

Role of adipose tissue renin–angiotensin system in metabolic and inflammatory diseases associated with obesity

inferredcites →https://doi.org/10.1038/ng0398-231openalex-snapshot

Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice

inferredcites →https://doi.org/10.1038/oby.2006.317openalex-snapshot

Adipose Tissue as an Endocrine Organ

inferredcites →https://doi.org/10.1038/oby.2009.152openalex-snapshot

Mitochondrial DNA: An Up‐and‐coming Actor in White Adipose Tissue Pathophysiology

inferredcites →https://doi.org/10.1079/pns2004408openalex-snapshot

Respiration uncoupling and metabolism in the control of energy expenditure

inferredcites →https://doi.org/10.1096/fj.01-0457fjeopenalex-snapshot

Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation

inferredcites →https://doi.org/10.1097/00002030-200411050-00004openalex-snapshot

The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro

inferredcites →https://doi.org/10.1097/md.0b013e3181e9442fopenalex-snapshot

Cardiomyopathy in Congenital and Acquired Generalized Lipodystrophy

inferredcites →https://doi.org/10.1101/gad.1681308openalex-snapshot

Molecular determinants of brown adipocyte formation and function: Figure 1.

inferredcites →https://doi.org/10.1111/j.1540-8175.2006.00356.xopenalex-snapshot

Echocardiographic Evaluation of Ventricular Function in Mice

inferredcites →https://doi.org/10.1126/science.1172539openalex-snapshot

Extending Healthy Life Span—From Yeast to Humans

inferredcites →https://doi.org/10.1136/hrt.2008.161463openalex-snapshot

Cardiovascular manifestations of HIV infection

inferredcites →https://doi.org/10.1152/ajpheart.01092.2010openalex-snapshot

Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart

inferredcites →https://doi.org/10.1159/000345030openalex-snapshot

‘Small Changes' to Diet and Physical Activity Behaviors for Weight Management

inferredcites →https://doi.org/10.1161/circresaha.108.189779openalex-snapshot

Angiotensin II–Mediated Adaptive and Maladaptive Remodeling of Cardiomyocyte Excitation–Contraction Coupling

inferredcites →https://doi.org/10.1161/res.0b013e3181bc39fcopenalex-snapshot

Correction

inferredcites →https://doi.org/10.1210/er.2009-0027openalex-snapshot

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

inferredcites →https://doi.org/10.1310/hct1102-100openalex-snapshot

Aging and HIV Infection: A Comparison Between Older HIV-Infected Persons and the General Population

inferredcites →https://doi.org/10.1371/journal.pone.0029691openalex-snapshot

Thymidine Kinase 2 Deficiency-Induced Mitochondrial DNA Depletion Causes Abnormal Development of Adipose Tissues and Adipokine Levels in Mice

inferredcites →https://doi.org/10.2174/092986712803833164openalex-snapshot

Protective Role of Adiponectin in Cardiovascular Disease

inferredcites →https://doi.org/10.2174/13816128113196660700openalex-snapshot

Bioenergetics and Mitochondrial Dysfunction in Aging: Recent Insights for a Therapeutical Approach

inferredcites →https://doi.org/10.2337/db07-0510openalex-snapshot

Essential Role of Mitochondrial Function in Adiponectin Synthesis in Adipocytes

inferredcites →https://doi.org/10.2337/db12-1089openalex-snapshot

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

inferredcites →https://doi.org/10.2353/ajpath.2009.081155openalex-snapshot

Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations

inferredcites →https://doi.org/10.4149/endo_2013_01_39openalex-snapshot

Renin-angiotensin system: upgrade of recent knowledge and perspectives

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Mitochondrial fractions located in the cytoplasmic and peridroplet areas of white adipocytes have distinct roles

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Proteomic and Metabolite Profiling Reveals Profound Structural and Metabolic Reorganization of Adipocyte Mitochondria in Obesity

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Metabolically unhealthy adipose tissue is characterized by reductions in mitochondrial size and function

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An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models

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Differences in tissue-specific insulin resistance between South Asian and Nordic women with prediabetes after gestational diabetes

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Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages

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HYPOTHesizing about central comBAT against obesity

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Aerobic exercise training combined with enalapril treatment improves obesity-induced brown adipose tissue whitening

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The Whitening of Brown Fat and Its Implications for Weight Management in Obesity

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Decoding Adipose Tissue Phenotypic Switching: From Mechanisms to Computational Drug Discovery

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Calcium in Obesity and Related Diseases

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Role of Mitochondria in Adipose Tissues Metabolism and Plasticity

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Managing Metabolic Health Impact of Fructose-Containing Beverages

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Tissue specificity of energy metabolism in mitochondria

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Mitochondrial dysfunction and metabolic syndrome

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Creatine monohydrate for mitochondrial nutrition

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Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies

inferred← citeshttps://doi.org/10.1016/j.addr.2026.115971openalex-snapshot

Adipose tissue-on-Chip platforms for disease modelling, drug discovery and pharmacokinetic modelling

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Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

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Pleiotropic and multi-systemic actions of physical exercise on PGC-1α signaling during the aging process

inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2025.120424openalex-snapshot

Unlocking the secrets: Adipose tissue dysfunction and atherosclerosis-mechanisms and innovative therapeutic approaches

inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115337openalex-snapshot

Adipose tissue mitochondrial dysfunction and cardiometabolic diseases: On the search for novel molecular targets

inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112019openalex-snapshot

Impaired brown adipose tissue is differentially modulated in insulin-resistant obese wistar and type 2 diabetic Goto-Kakizaki rats

inferred← citeshttps://doi.org/10.1016/j.celrep.2016.08.041openalex-snapshot

Role of Mitochondrial Complex IV in Age-Dependent Obesity

inferred← citeshttps://doi.org/10.1016/j.clnu.2016.09.010openalex-snapshot

Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group

inferred← citeshttps://doi.org/10.1016/j.cmet.2018.01.018openalex-snapshot

Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits

inferred← citeshttps://doi.org/10.1016/j.cmet.2018.05.003openalex-snapshot

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.04.028openalex-snapshot

A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice

inferred← citeshttps://doi.org/10.1016/j.gene.2025.149734openalex-snapshot

Cetacean-specific GPR12 mutation is functionally associated with blubber thickening

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e26867openalex-snapshot

A comparative transcriptomics analysis reveals ethylene glycol derivatives of squalene ameliorate excessive lipogenesis and inflammatory response in 3T3-L1 preadipocytes

inferred← citeshttps://doi.org/10.1016/j.humgen.2023.201198openalex-snapshot

Cell-Free Mitochondrial DNA as a Novel biomarker for stress-related conditions - Meta-Analysis

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.145706openalex-snapshot

Mitochondrial transcription factor a as a guardian of mitochondrial integrity and emerging therapeutic target in human diseases: A review

inferred← citeshttps://doi.org/10.1016/j.isci.2022.104889openalex-snapshot

TFAM expression in brown adipocytes confers obesity resistance by secreting extracellular vesicles that promote self-activation

inferred← citeshttps://doi.org/10.1016/j.jhepr.2023.100714openalex-snapshot

Pathological bile acid concentrations in chronic cholestasis cause adipose mitochondrial defects

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.07.008openalex-snapshot

A polyphenolic extract from green tea leaves activates fat browning in high-fat-diet-induced obese mice

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2025.110040openalex-snapshot

Dietary cannabidiol oil mitigates metabolic dysfunction in mice with high-fat diet-induced obesity

inferred← citeshttps://doi.org/10.1016/j.jsbmb.2018.09.013openalex-snapshot

GPER and ERα mediate estradiol enhancement of mitochondrial function in inflamed adipocytes through a PKA dependent mechanism

inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119620openalex-snapshot

MicroRNA-489-3p promotes adipogenesis by targeting the Postn gene in 3T3-L1 preadipocytes

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Sco2 deficient mice develop increased adiposity and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.mce.2020.111137openalex-snapshot

Developmental programming: Adipose depot-specific transcriptional regulation by prenatal testosterone excess in a sheep model of PCOS

inferred← citeshttps://doi.org/10.1016/j.mito.2023.07.004openalex-snapshot

Mitochondrial respiratory complex I deficiency inhibits brown adipogenesis by limiting heme regulation of histone demethylation

inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101220openalex-snapshot

Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function

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Metabolic beneficial effects of targeting a long non-coding RNA, lnc-megacluster, in obesity

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Cajanolactone A, a stilbenoid from cajanus cajan, prevents ovariectomy-induced obesity and liver steatosis in mice fed a regular diet

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Shortcuts to a functional adipose tissue: The role of small non-coding RNAs

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Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health

inferred← citeshttps://doi.org/10.1016/j.redox.2020.101507openalex-snapshot

Low steady-state oxidative stress inhibits adipogenesis by altering mitochondrial dynamics and decreasing cellular respiration

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The biology of lipid droplet-bound mitochondria

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Stress-induced FGF21 and GDF15 in obesity and obesity resistance

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A hypomorphic variant in the translocase of the outer mitochondrial membrane complex subunit TOMM7 causes short stature and developmental delay

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Spexin modulates molecular thermogenic profile of adipose tissue and thermoregulatory behaviors in female C57BL/6 mice

inferred← citeshttps://doi.org/10.1038/s41467-018-05933-8openalex-snapshot

LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

inferred← citeshttps://doi.org/10.1038/s41467-022-30629-5openalex-snapshot

Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

inferred← citeshttps://doi.org/10.1038/s41467-024-52968-1openalex-snapshot

Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibition

inferred← citeshttps://doi.org/10.1038/s41598-017-01879-xopenalex-snapshot

Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression

inferred← citeshttps://doi.org/10.1038/s41598-019-43410-4openalex-snapshot

Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria

inferred← citeshttps://doi.org/10.1038/s41598-025-97307-6openalex-snapshot

Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions

inferred← citeshttps://doi.org/10.1038/s42255-018-0021-8openalex-snapshot

Metabolic adaptation and maladaptation in adipose tissue

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PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

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2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction

inferred← citeshttps://doi.org/10.1038/s44318-024-00335-7openalex-snapshot

MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis

inferred← citeshttps://doi.org/10.1080/01443615.2026.2681758openalex-snapshot

Elevated non-esterified fatty acids in obese women with late-onset preeclampsia: a cross-sectional study

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Could very low-calorie ketogenic diets turn off low grade inflammation in obesity? Emerging evidence

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Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance

inferred← citeshttps://doi.org/10.1093/gerona/glab356openalex-snapshot

Ameliorating Effects of Lifelong Physical Activity on Healthy Aging and Mitochondrial Function in Human White Adipose Tissue

inferred← citeshttps://doi.org/10.1093/hmg/ddad100openalex-snapshot

Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria

inferred← citeshttps://doi.org/10.1093/hmg/ddae020openalex-snapshot

Illuminating mitochondrial translation through mouse models

inferred← citeshttps://doi.org/10.1096/fasebj.2019.33.1_supplement.lb302openalex-snapshot

Bile Acid Excess Impairs Thermogenic Function in Brown Adipose Tissue

inferred← citeshttps://doi.org/10.1096/fj.201901743ropenalex-snapshot

Neuromedin U suppresses insulin secretion by triggering mitochondrial dysfunction and endoplasmic reticulum stress in pancreatic β‐cells

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Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue

inferred← citeshttps://doi.org/10.1097/mco.0000000000000380openalex-snapshot

AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity

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Spexin modulates molecular thermogenic profile of adipose tissue and thermoregulatory behaviors

inferred← citeshttps://doi.org/10.1101/2022.03.02.482658openalex-snapshot

Critical role of PCYT2 in muscle health and aging

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Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis

inferred← citeshttps://doi.org/10.1101/2023.12.15.571941openalex-snapshot

High-energy demand and nutrient exhaustion in MTCH2 knockout cells

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Hepatic mitochondrial respiration is crucial for euthermia in complex III-deficient mice with impaired brown adipose tissue thermogenesis

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Adipose tissue and metabolic syndrome: too much, too little or neither

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Energy metabolism of white adipose tissue and insulin resistance in humans

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Metabolic imaging in obesity: underlying mechanisms and consequences in the whole body

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Effects of ramelteon on cardiac injury and adipose tissue pathology in rats with metabolic syndrome

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White adipose tissue mitochondrial metabolism in health and in obesity

inferred← citeshttps://doi.org/10.1146/annurev-nutr-071715-050656openalex-snapshot

Alterations of Mitochondrial Function and Insulin Sensitivity in Human Obesity and Diabetes Mellitus

inferred← citeshttps://doi.org/10.1152/ajpendo.00057.2018openalex-snapshot

NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism

inferred← citeshttps://doi.org/10.1152/ajpheart.00473.2018openalex-snapshot

Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin-angiotensin system

inferred← citeshttps://doi.org/10.1155/2016/6067349openalex-snapshot

Mitochondria in White, Brown, and Beige Adipocytes

inferred← citeshttps://doi.org/10.1155/2019/7210892openalex-snapshot

Mitochondrial Dysfunctions: A Thread Sewing Together Alzheimer’s Disease, Diabetes, and Obesity

inferred← citeshttps://doi.org/10.1155/2019/9570616openalex-snapshot

Advanced Glycation End Products: Potential Mechanism and Therapeutic Target in Cardiovascular Complications under Diabetes

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Expressão heteróloga em Saccharomyces cerevisiae da translocase de membrana mitocondrial externa Tom20 de Aspergillus fumigatus

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CITED4 Protects Against Adverse Remodeling in Response to Physiological and Pathological Stress

inferred← citeshttps://doi.org/10.1172/jci.insight.136283openalex-snapshot

GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity

inferred← citeshttps://doi.org/10.1172/jci.insight.97293openalex-snapshot

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity

inferred← citeshttps://doi.org/10.1186/1750-1172-10-s2-o21openalex-snapshot

Irisin levels in LMNA-mutated lipodystrophic syndromes

inferred← citeshttps://doi.org/10.1186/s10020-022-00496-3openalex-snapshot

Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes

inferred← citeshttps://doi.org/10.1186/s12967-016-0999-1openalex-snapshot

Type 2 diabetes is associated with decreased PGC1α expression in epicardial adipose tissue of patients with coronary artery disease

inferred← citeshttps://doi.org/10.1186/s12979-020-00212-xopenalex-snapshot

Obesity and COVID-19: what makes obese host so vulnerable?

inferred← citeshttps://doi.org/10.1186/s12986-017-0191-5openalex-snapshot

Supramolecular structure of dietary fat in early life modulates expression of markers for mitochondrial content and capacity in adipose tissue of adult mice

inferred← citeshttps://doi.org/10.1186/s12986-017-0209-zopenalex-snapshot

DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes

inferred← citeshttps://doi.org/10.1186/s13098-019-0494-yopenalex-snapshot

Comparison of visceral adipose tissue DNA methylation and gene expression profiles in female adolescents with obesity

inferred← citeshttps://doi.org/10.1186/s13148-023-01556-zopenalex-snapshot

Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

inferred← citeshttps://doi.org/10.1210/clinem/dgab725openalex-snapshot

Impaired Muscle Mitochondrial Function in Familial Partial Lipodystrophy

inferred← citeshttps://doi.org/10.1210/clinem/dgz267openalex-snapshot

Expansion and Impaired Mitochondrial Efficiency of Deep Subcutaneous Adipose Tissue in Recent-Onset Type 2 Diabetes

inferred← citeshttps://doi.org/10.1210/en.2016-1148openalex-snapshot

Severe Brown Fat Lipoatrophy Aggravates Atherosclerotic Process in Male Mice

inferred← citeshttps://doi.org/10.1210/endocr/bqaa096openalex-snapshot

Exposure to Low Doses of Dechlorane Plus Promotes Adipose Tissue Dysfunction and Glucose Intolerance in Male Mice

inferred← citeshttps://doi.org/10.1210/endocr/bqac018openalex-snapshot

Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner

inferred← citeshttps://doi.org/10.1210/endocr/bqad019openalex-snapshot

Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice

inferred← citeshttps://doi.org/10.1210/jc.2015-3336openalex-snapshot

Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans

inferred← citeshttps://doi.org/10.1210/jendso/bvz022openalex-snapshot

Metabolomic Analysis of the Effects of Leptin Replacement Therapy in Patients with Lipodystrophy

inferred← citeshttps://doi.org/10.1242/dmm.048995openalex-snapshot

TFAM-deficient mouse skin fibroblasts – an ex vivo model of mitochondrial dysfunction

inferred← citeshttps://doi.org/10.13028/m2np4fopenalex-snapshot

Role of Energy Metabolism in the Thermogenic Gene Program

inferred← citeshttps://doi.org/10.1371/journal.pgen.1009018openalex-snapshot

The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance

inferred← citeshttps://doi.org/10.1371/journal.pone.0306243openalex-snapshot

Loss of Mfn1 but not Mfn2 enhances adipogenesis

inferred← citeshttps://doi.org/10.1515/hmbci-2014-0048openalex-snapshot

The role of perivascular adipose tissue in vasoconstriction, arterial stiffness, and aneurysm

inferred← citeshttps://doi.org/10.15252/embj.201694914openalex-snapshot

Mfn2 is critical for brown adipose tissue thermogenic function

inferred← citeshttps://doi.org/10.15252/embj.201797572openalex-snapshot

Seipin regulates lipid homeostasis by ensuring calcium‐dependent mitochondrial metabolism

inferred← citeshttps://doi.org/10.15252/embr.201745126openalex-snapshot

CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis

inferred← citeshttps://doi.org/10.1530/joe-18-0361openalex-snapshot

The depot-specific and essential roles of CBP/p300 in regulating adipose plasticity

inferred← citeshttps://doi.org/10.18174/644648openalex-snapshot

Nutritional programming of white adipose tissue and mitochondrial function : Fat quality matters

inferred← citeshttps://doi.org/10.18632/aging.100970openalex-snapshot

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

inferred← citeshttps://doi.org/10.2174/0929867327666200505090449openalex-snapshot

The Roles of Dietary, Nutritional and Lifestyle Interventions in Adipose Tissue Adaptation and Obesity

inferred← citeshttps://doi.org/10.2174/9789815124484123010013openalex-snapshot

Role of Taurine Supplementation in Obesity: Stimulating Fats to Burn in Cellular Power Plants

inferred← citeshttps://doi.org/10.2337/db16-0136openalex-snapshot

Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance

inferred← citeshttps://doi.org/10.2337/db16-0212openalex-snapshot

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

inferred← citeshttps://doi.org/10.2337/db16-1232openalex-snapshot

Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance

inferred← citeshttps://doi.org/10.23880/cclsj-16000179openalex-snapshot

Avoidance of Whitening of Brownadipose Tissue (BAT/Beige Adipose Tissue (BeAT)-as an Innovative Target of Obesity/Ageing Prevention-A Mini Review

inferred← citeshttps://doi.org/10.26508/lsa.202301934openalex-snapshot

Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size

inferred← citeshttps://doi.org/10.33549/physiolres.935653openalex-snapshot

Nrf2 Overexpression in Spontaneously Hypertensive Rats Enhances Adipose Tissue Metabolism through Redox-Mediated Suppression of Mitochondrial Oxidative Phosphorylation

inferred← citeshttps://doi.org/10.3389/fendo.2015.00104openalex-snapshot

Role of Energy Metabolism in the Brown Fat Gene Program

inferred← citeshttps://doi.org/10.3389/fendo.2020.00156openalex-snapshot

Inflammatory Signaling and Brown Fat Activity

inferred← citeshttps://doi.org/10.3389/fendo.2020.607113openalex-snapshot

Electroacupuncture Regulates Inguinal White Adipose Tissue Browning by Promoting Sirtuin-1-Dependent PPARγ Deacetylation and Mitochondrial Biogenesis

inferred← citeshttps://doi.org/10.3389/fendo.2023.1114767openalex-snapshot

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

inferred← citeshttps://doi.org/10.3389/fphar.2024.1309178openalex-snapshot

Isorhamnetin: what is the in vitro evidence for its antitumor potential and beyond?

inferred← citeshttps://doi.org/10.3389/fphys.2015.00020openalex-snapshot

Nitric oxide and mitochondria in metabolic syndrome

inferred← citeshttps://doi.org/10.3389/fphys.2018.00112openalex-snapshot

Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity

inferred← citeshttps://doi.org/10.3389/fphys.2023.1261204openalex-snapshot

The regulatory role of adipocyte mitochondrial homeostasis in metabolism-related diseases

inferred← citeshttps://doi.org/10.3390/antiox12010165openalex-snapshot

Prevalence of Hypertension and Obesity: Profile of Mitochondrial Function and Markers of Inflammation and Oxidative Stress

inferred← citeshttps://doi.org/10.3390/antiox12051137openalex-snapshot

Overexpression of Mitochondrial Catalase within Adipose Tissue Does Not Confer Systemic Metabolic Protection against Diet-Induced Obesity

inferred← citeshttps://doi.org/10.3390/cimb46080523openalex-snapshot

ROS Chronicles in HIV Infection: Genesis of Oxidative Stress, Associated Pathologies, and Therapeutic Strategies

inferred← citeshttps://doi.org/10.3390/genes13101866openalex-snapshot

Obesity and Adipose Tissue Dysfunction: From Pediatrics to Adults

inferred← citeshttps://doi.org/10.3390/ijms20143520openalex-snapshot

Suppression of Brown Adipocyte Autophagy Improves Energy Metabolism by Regulating Mitochondrial Turnover

inferred← citeshttps://doi.org/10.3390/ijms20194924openalex-snapshot

The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases

inferred← citeshttps://doi.org/10.3390/ijms20235870openalex-snapshot

Adipose Tissue Mitochondrial Factors Profile after Dietary Bioactive Compound Weight Reduction Treatments in a Mice Obesity Model

inferred← citeshttps://doi.org/10.3390/ijms21239042openalex-snapshot

Visceral Obesity and Its Shared Role in Cancer and Cardiovascular Disease: A Scoping Review of the Pathophysiology and Pharmacological Treatments

inferred← citeshttps://doi.org/10.3390/ijms22062854openalex-snapshot

Mitochondrial Unfolded Protein Responses in White Adipose Tissue: Lipoatrophy, Whole-Body Metabolism and Lifespan

inferred← citeshttps://doi.org/10.3390/ijms23158659openalex-snapshot

Cellular Metabolism and Bioenergetic Function in Human Fibroblasts and Preadipocytes of Type 2 Familial Partial Lipodystrophy

inferred← citeshttps://doi.org/10.3390/ijms24021352openalex-snapshot

Mitochondrial Energy Metabolism in the Regulation of Thermogenic Brown Fats and Human Metabolic Diseases

inferred← citeshttps://doi.org/10.3390/ijms24108650openalex-snapshot

Mitochondrial Dysfunction: At the Nexus between Alcohol-Associated Immunometabolic Dysregulation and Tissue Injury

inferred← citeshttps://doi.org/10.3390/ijms25126681openalex-snapshot

Adipocyte Mitochondria: Deciphering Energetic Functions across Fat Depots in Obesity and Type 2 Diabetes

inferred← citeshttps://doi.org/10.3390/ijms26157398openalex-snapshot

Impaired Mitochondrial DNA Copy Number in Visceral Adipose Tissue of Insulin-Resistant Individuals: Implications for Metabolic Dysregulation

inferred← citeshttps://doi.org/10.3390/jpm10020042openalex-snapshot

Obesity and Diabetes Mediated Chronic Inflammation: A Potential Biomarker in Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3390/molecules23081853openalex-snapshot

Effects of Isorhamnetin on Adipocyte Mitochondrial Biogenesis and AMPK Activation

inferred← citeshttps://doi.org/10.3390/molecules24020340openalex-snapshot

Plant-Derived Oleanolic Acid (OA) Ameliorates Risk Factors of Cardiovascular Diseases in a Diet-Induced Pre-Diabetic Rat Model: Effects on Selected Cardiovascular Risk Factors

inferred← citeshttps://doi.org/10.3390/pharmaceutics14102134openalex-snapshot

The Anti-Obesity Potential of Superparamagnetic Iron Oxide Nanoparticles against High-Fat Diet-Induced Obesity in Rats: Possible Involvement of Mitochondrial Biogenesis in the Adipose Tissues

inferred← citeshttps://doi.org/10.3410/f.726287926.793562571openalex-snapshot

Faculty Opinions recommendation of Mitochondria in white, brown, and beige adipocytes.

inferred← citeshttps://doi.org/10.3803/enm.2021.956openalex-snapshot

Cellular and Intercellular Homeostasis in Adipose Tissue with Mitochondria-Specific Stress

inferred← citeshttps://doi.org/10.3803/enm.2023.1813openalex-snapshot

The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least

inferred← citeshttps://doi.org/10.4093/dmj.2018.0221openalex-snapshot

Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation

inferred← citeshttps://doi.org/10.4093/dmj.2023.0011openalex-snapshot

Adipose Tissue and Metabolic Health

inferred← citeshttps://doi.org/10.4239/wjd.v6.i6.850openalex-snapshot

Diabetes mellitus: The epidemic of the century

inferred← citeshttps://doi.org/10.46989/001c.165930openalex-snapshot

Effects of different diets on the edible quality and flavor-related compounds of Chinese mitten crab ( Eriocheir sinensis )

inferred← citeshttps://doi.org/10.47749/t/unicamp.2018.1051961openalex-snapshot

Efeitos das erva-mate (Ilex paraguariensis) na modulação do metabolismo energético mitocondrial associado à obesidade

inferred← citeshttps://doi.org/10.54133/ajms.v1i.23openalex-snapshot

Glycation End-Products and their Receptors: Pathophysiology and Therapeutic Targeting in Diabetes Mellitus

inferred← citeshttps://doi.org/10.6084/m9.figshare.20098343openalex-snapshot

Additional file 1 of Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes

inferred← citeshttps://doi.org/10.6084/m9.figshare.26615680openalex-snapshot

Additional file 1 of Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

inferred← citeshttps://doi.org/10.6084/m9.figshare.26615683openalex-snapshot

Additional file 2 of Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

inferred← citeshttps://doi.org/10.6084/m9.figshare.26615686openalex-snapshot

Additional file 3 of Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

inferred← citeshttps://doi.org/10.7150/jca.16884openalex-snapshot

Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

inferred← citeshttps://doi.org/10.7570/jomes24013openalex-snapshot

Understanding Adipose Tissue Dysfunction

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.