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Does Ischemia Time Affect the Outcome of Free Fibula Flaps for Head and Neck Reconstruction? A Review of 116 Cases

https://doi.org/10.1097/prs.0b013e3181f448c8
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hed.20345openalex-snapshot
Osteomyocutaneous peroneal artery perforator flap for reconstruction of composite maxillary defects
inferredcites →https://doi.org/10.1002/hed.20969openalex-snapshot
Osteomyocutaneous peroneal artery–based combined flap for reconstruction of composite and en bloc mandibular defects
inferredcites →https://doi.org/10.1002/hed.2880170103openalex-snapshot
Risk factors for complications in clean‐contaminated head and neck surgical procedures
inferredcites →https://doi.org/10.1002/micr.1920140307openalex-snapshot
Ischemia reperfusion injury: A review
inferredcites →https://doi.org/10.1016/0002-9610(83)90247-7openalex-snapshot
Major complications of radiotherapy in cancer of the oral cavity and oropharynx
inferredcites →https://doi.org/10.1016/0007-1226(90)90003-iopenalex-snapshot
Mandibular reconstruction using vascularised fibula
inferredcites →https://doi.org/10.1016/s0094-1298(20)31187-1openalex-snapshot
Biology Of Chronic Radiation Effect On Tissues And Wound Healing
inferredcites →https://doi.org/10.1016/s0094-1298(20)31191-3openalex-snapshot
Long-Term Effects Of Radiation Therapy In The Head And Neck
inferredcites →https://doi.org/10.1016/s0094-1298(20)31192-5openalex-snapshot
Management Of Radiation-Induced Soft-Tissue Injury To The Head And Neck
inferredcites →https://doi.org/10.1016/s0901-5027(05)80583-1openalex-snapshot
Fibula free flap: A new method of mandible reconstruction
inferredcites →https://doi.org/10.1097/00006534-197505000-00002openalex-snapshot
THE FREE VASCULARIZED BONE GRAFT
inferredcites →https://doi.org/10.1097/00006534-197802000-00017openalex-snapshot
THE NO-REFLOW PHENOMENON IN EXPERIMENTAL FREE FLAPS
inferredcites →https://doi.org/10.1097/00006534-198608000-00008openalex-snapshot
Fibular Osteoseptocutaneous Flap: Anatomic Study and Clinical Application
inferredcites →https://doi.org/10.1097/00006534-198907000-00014openalex-snapshot
Fibula Free Flap
inferredcites →https://doi.org/10.1097/00006534-199804040-00006openalex-snapshot
Fibula Osteoseptocutaneous Flap for Reconstruction of Osteoradionecrosis of the Mandible
inferredcites →https://doi.org/10.1097/00006534-199901000-00008openalex-snapshot
Double Free Flaps in Reconstruction of Extensive Composite Mandibular Defects in Head and Neck Cancer
inferredcites →https://doi.org/10.1097/00006534-199904020-00012openalex-snapshot
The Vascularized Pig Fibula Bone Flap Model: Effects of Multiple Segmental Osteotomies on Growth and Viability
inferredcites →https://doi.org/10.1097/00006534-199907000-00014openalex-snapshot
Efficacy of Conventional Monitoring Techniques in Free Tissue Transfer: An 11-Year Experience in 750 Consecutive Cases
inferredcites →https://doi.org/10.1097/01.prs.0000225432.17501.6copenalex-snapshot
Nutrition and Wound Healing
inferredcites →https://doi.org/10.2106/00004623-198365090-00011openalex-snapshot
Free vascularized fibular transplant. A new method for monitoring circulation of the grafted fibula.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4000248openalex-extracted
Computer-Aided Surgery for Presurgical Planning Versus Conventional Freehand Surgery in Mandibular Reconstruction Using Free Fibular Flap: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1002/hed.24506openalex-snapshot
Infrazygomatico‐coronoid fixation in a segmental mandibular reconstruction with a free vascularized flap: A simple and correct repositioning method without interfering with reconstructive and microsurgical procedures
inferred← citeshttps://doi.org/10.1002/hed.24796openalex-snapshot
Impact of venous outflow tract on survival of osteocutaneous free fibula flaps for mandibular reconstruction: A 14‐year review
inferred← citeshttps://doi.org/10.1002/hed.25525openalex-snapshot
Clinical pathway for abbreviated postoperative hospital stay in free tissue transfer to the head and neck: Impact in resource utilization and surgical outcomes
inferred← citeshttps://doi.org/10.1002/hed.27112openalex-snapshot
Analysis of cost and outcomes in bony versus soft tissue midface free flap reconstruction
inferred← citeshttps://doi.org/10.1002/lary.28650openalex-snapshot
The Shape of Things to Come: In‐Hospital Three‐Dimensional Printing for Mandibular Reconstruction Using Fibula Free Flap
inferred← citeshttps://doi.org/10.1002/lary.29379openalex-snapshot
Accuracy of Fibula Reconstruction Using Patient‐Specific Cad/Cam Plates: A Multicenter Study on 47 Patients
inferred← citeshttps://doi.org/10.1002/lary.31171openalex-snapshot
A 3D Analysis of Plating Strategies in Mandibular Reconstruction: A Randomized Control Pilot Study
inferred← citeshttps://doi.org/10.1002/micr.22046openalex-snapshot
Micro‐RNA profiling as biomarkers in flap ischemia–reperfusion injury
inferred← citeshttps://doi.org/10.1002/micr.22212openalex-snapshot
Free tissue transfers in head and neck reconstruction: Complications, outcomes and strategies for management of flap failure: Analysis of 2019 flaps in single institute
inferred← citeshttps://doi.org/10.1002/micr.30720openalex-snapshot
Three salvage strategies in microvascular fibula osteocutaneous flap for mandible reconstruction with vascular compromise and establishment of an algorithm
inferred← citeshttps://doi.org/10.1002/micr.30881openalex-snapshot
Strategy for preventing skin paddle necrosis in mandibular reconstruction with free fibula osteocutaneous flap
inferred← citeshttps://doi.org/10.1007/978-3-030-74322-2_7openalex-snapshot
Computer-Assisted Surgery in Mandibular Reconstruction
inferred← citeshttps://doi.org/10.1007/978-3-030-75389-4_29openalex-snapshot
Recipient Vessels: Radius Reconstruction
inferred← citeshttps://doi.org/10.1007/978-3-031-38898-9_9openalex-snapshot
Flap Monitoring
inferred← citeshttps://doi.org/10.1007/978-981-13-2444-4_6openalex-snapshot
Mandible Reconstruction with Free Fibula Flap
inferred← citeshttps://doi.org/10.1007/s10006-015-0493-6openalex-snapshot
Comparison of intraoperative time measurements between osseous reconstructions with free fibula flaps applying computer-aided designed/computer-aided manufactured and conventional techniques
inferred← citeshttps://doi.org/10.1007/s12282-021-01274-5openalex-snapshot
Microsurgical techniques in the treatment of breast cancer-related lymphedema: a systematic review of efficacy and patient outcomes
inferred← citeshttps://doi.org/10.1007/s40137-016-0129-2openalex-snapshot
Preoperative Head and Neck Surgical Planning with Computer-Assisted Design and Modeling
inferred← citeshttps://doi.org/10.1016/b978-0-323-26568-3.00007-5openalex-snapshot
Virtual Surgical Planning
inferred← citeshttps://doi.org/10.1016/j.actbio.2021.09.053openalex-snapshot
Skeletal regeneration for segmental bone loss: Vascularised grafts, analogues and surrogates
inferred← citeshttps://doi.org/10.1016/j.adoms.2026.100669openalex-snapshot
Fibular free flaps for mandibular reconstruction: symphysis is at higher risk
inferred← citeshttps://doi.org/10.1016/j.aforl.2015.09.006openalex-snapshot
Modélisation tridimensionnelle préopératoire avec guide de coupes dans la reconstruction mandibulaire par lambeau libre de fibula : à propos d’une série de 29 cas
inferred← citeshttps://doi.org/10.1016/j.aforl.2017.05.003openalex-snapshot
Comment utiliser à moindre coût l’impression 3D comme aide à la reconstruction mandibulaire ?
inferred← citeshttps://doi.org/10.1016/j.amjoto.2022.103467openalex-snapshot
Impact of intraoperative ischemia time on acute complications of head and neck microvascular free tissue transfer: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.anorl.2016.01.009openalex-snapshot
Virtual planning and guided surgery in fibular free-flap mandibular reconstruction: A 29-case series
inferred← citeshttps://doi.org/10.1016/j.anorl.2017.09.007openalex-snapshot
Contribution of 3D printing to mandibular reconstruction after cancer
inferred← citeshttps://doi.org/10.1016/j.bjoms.2016.12.010openalex-snapshot
Mandibular reconstruction with vascularised bone flaps: a systematic review over 25 years
inferred← citeshttps://doi.org/10.1016/j.bjps.2012.08.024openalex-snapshot
Increments in ischaemia time induces microvascular complications in the DIEP flap for breast reconstruction
inferred← citeshttps://doi.org/10.1016/j.bjps.2012.09.020openalex-snapshot
Ischaemic time and fat necrosis in breast reconstruction with a free deep inferior epigastric perforator flap
inferred← citeshttps://doi.org/10.1016/j.bjps.2019.06.013openalex-snapshot
Virtual surgical planning in fibula free flap head and neck reconstruction: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.bjps.2023.08.026openalex-snapshot
Impact of fibula osteoseptocutaneous flap laterality in mandibular and intraoral reconstruction
inferred← citeshttps://doi.org/10.1016/j.bjps.2026.09.024openalex-snapshot
Factors Associated with Flap Loss Following Lower Limb Free Flap Reconstruction for Trauma: A 10-Year Retrospective Observational Study
inferred← citeshttps://doi.org/10.1016/j.coms.2025.04.003openalex-snapshot
Customized Surgical Plates for Computer-Assisted Maxillary and Mandibular Reconstruction
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Three-Dimensional Computer-Assisted Surgical Planning, Manufacturing, and Intraoperative Navigation in Oncologic Surgery
inferred← citeshttps://doi.org/10.1016/j.jcms.2012.11.008openalex-snapshot
Three-dimensional virtual technology in reconstruction of mandibular defect including condyle using double-barrel vascularized fibula flap
inferred← citeshttps://doi.org/10.1016/j.jcms.2016.04.003openalex-snapshot
Is a computer-assisted design and computer-assisted manufacturing method for mandibular reconstruction economically viable?
inferred← citeshttps://doi.org/10.1016/j.jcms.2019.11.024openalex-snapshot
Time matters – Differences between computer-assisted surgery and conventional planning in cranio-maxillofacial surgery: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.joms.2017.11.042openalex-snapshot
Using an In-House Approach to Computer-Assisted Design and Computer-Aided Manufacturing Reconstruction of the Maxilla
inferred← citeshttps://doi.org/10.1016/j.joms.2020.07.216openalex-snapshot
An In-House Computer-Aided Design and Computer-Aided Manufacturing Workflow for Maxillofacial Free Flap Reconstruction is Associated With a Low Cost and High Accuracy
inferred← citeshttps://doi.org/10.1016/j.jormas.2022.03.001openalex-snapshot
Aspirin, heparin and ischemia time in microvascular free flap surgery - their influence and an optimal anticoagulation protocol
inferred← citeshttps://doi.org/10.1016/j.jss.2016.06.096openalex-snapshot
Ex-vivo oxygenated perfusion of free flaps during ischemia time: a feasibility study in a porcine model and preliminary results
inferred← citeshttps://doi.org/10.1016/j.oooo.2016.02.001openalex-snapshot
Computer-assisted navigation: its role in intraoperatively accurate mandibular reconstruction
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The role of computer aided design/computer assisted manufacturing (CAD/CAM) and 3- dimensional printing in head and neck oncologic surgery: A review and future directions
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2024.106910openalex-snapshot
Division versus de-epithelialization of fibula osteocutaneous flap for composite oromandibular defects: A propensity score-matched analysis
inferred← citeshttps://doi.org/10.1016/j.revsto.2014.07.006openalex-snapshot
The use of 3D planning in facial surgery: Preliminary observations
inferred← citeshttps://doi.org/10.1055/s-0037-1606537openalex-snapshot
Quality of Life after Free Fibula Flap Reconstruction of Segmental Mandibular Defects
inferred← citeshttps://doi.org/10.1055/s-0037-1621729openalex-snapshot
Impact of Duration of Perioperative Ischemia on Outcomes of Microsurgical Reconstructions
inferred← citeshttps://doi.org/10.1055/s-0038-1639377openalex-snapshot
Does Cigarette Smoking Harm Microsurgical Free Flap Reconstruction?
inferred← citeshttps://doi.org/10.1055/s-0038-1651515openalex-snapshot
Fibula Free Flap in Head and Neck Reconstruction: Identifying Risk Factors for Flap Failure and Analysis of Postoperative Complications in a Low Volume Setting
inferred← citeshttps://doi.org/10.1055/s-0040-1716858openalex-snapshot
Adverse Events Associated with Implantable Dopplers during Microvascular Surgery
inferred← citeshttps://doi.org/10.1055/s-0041-1733994openalex-snapshot
Red Blood Cell Transfusion and its Relationship with Pedicle Thrombosis in Microvascular Free Flaps
inferred← citeshttps://doi.org/10.1055/s-0042-1757182openalex-snapshot
The Future of Microsurgery: Vascularized Composite Allotransplantation and Engineering Vascularized Tissue
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Role of Indocyanine Green Angiography in Free Flap Surgery: A Comparative Outcome Analysis of a Single-Center Large Series of 877 Consecutive Free Flaps
inferred← citeshttps://doi.org/10.1097/gox.0000000000006108openalex-snapshot
Implementation of In-house Computer-aided Design and Manufacturing for Accelerated Free Fibula Flap Reconstruction of Mandibular Defects in Cancer Patients
inferred← citeshttps://doi.org/10.1097/moo.0b013e328355d0f3openalex-snapshot
Reconstruction of the segmental mandibular defect
inferred← citeshttps://doi.org/10.1097/prs.0000000000004673openalex-snapshot
Critical Ischemia Time, Perfusion, and Drainage Function of Vascularized Lymph Nodes
inferred← citeshttps://doi.org/10.1097/prs.0000000000005418openalex-snapshot
Cost-Effectiveness Analysis of Virtual Surgical Planning in Mandibular Reconstruction
inferred← citeshttps://doi.org/10.1097/prs.0000000000008085openalex-snapshot
Computer-Aided Design and Manufacturing versus Conventional Surgical Planning for Head and Neck Reconstruction: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1097/prs.0000000000010512openalex-snapshot
Application of a Microsuction Background Device for Microanastomosis in a Rat Femoral Vessel Model [RETRACTED]
inferred← citeshttps://doi.org/10.1097/prs.0b013e3182a3c0b1openalex-snapshot
Computer-Assisted versus Conventional Free Fibula Flap Technique for Craniofacial Reconstruction
inferred← citeshttps://doi.org/10.1097/sap.0000000000002006openalex-snapshot
Virtual Surgical Planning for Mandibular Reconstruction With the Fibula Free Flap
inferred← citeshttps://doi.org/10.1097/sap.0000000000002915openalex-snapshot
Prospective Trial of Near-Infrared Spectroscopy for Continuous Noninvasive Monitoring of Free Fibular Flaps
inferred← citeshttps://doi.org/10.1097/sap.0b013e3182742c45openalex-snapshot
MicroRNA Signatures in Ischemia-Reperfusion Injury
inferred← citeshttps://doi.org/10.1097/scs.0000000000003591openalex-snapshot
A Thirty-Year Experience With Head and Neck Flap Reconstruction
inferred← citeshttps://doi.org/10.1097/scs.0000000000007417openalex-snapshot
Fibula Free Flap Salvage From 10-hour Prolonged Arterial Insufficiency and Venous Thrombosis
inferred← citeshttps://doi.org/10.1097/scs.0000000000013359openalex-snapshot
Free Fibula Flap With Chimeric Skin Paddles: Technical Tips and Clinical Experience
inferred← citeshttps://doi.org/10.1097/scs.0b013e31828b7471openalex-snapshot
Maxillary Reconstruction Using Vascularized Fibular Osteomyocutaneous Flap and Iliac Bone Through Modified Lateral Lip-Submandibular Approach
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Computer‐Aided High Tibial Osteotomy—A Comparative Study of Commonly Used 3D Printing Technology and Navigation Application
inferred← citeshttps://doi.org/10.11124/jbisrir-2017-003875openalex-snapshot
Effectiveness of computer-assisted virtual planning, cutting guides and pre-engineered plates on outcomes in mandible fibular free flap reconstructions: a systematic review protocol
inferred← citeshttps://doi.org/10.1177/0194599819860809openalex-snapshot
Factors Associated with Free Flap Failures in Head and Neck Reconstruction
inferred← citeshttps://doi.org/10.1177/19160216241265089openalex-snapshot
Free Flap Perfusion in Microvascular Head and Neck Reconstruction: Influence of the Number of Ischemia Intervals and Ischemia Duration—A Retrospective Study
inferred← citeshttps://doi.org/10.1186/s12871-025-02975-6openalex-snapshot
Impact of perioperative anticoagulation management on free flap survival in reconstructive surgery: a retrospective analysis
inferred← citeshttps://doi.org/10.1186/s12885-025-13505-5openalex-snapshot
A multi-centre, participant-blinded, randomized, 3-year study to compare the efficacy of Virtual Surgical Planning (VSP) to Freehand Surgery (FHS) on bony union and quality of life outcomes for mandibular reconstruction with fibular and scapular free flaps: study protocol for a randomized phase…
inferred← citeshttps://doi.org/10.1186/s13256-026-06107-7openalex-snapshot
Pitfalls during mandible reconstruction with free fibula flap and its salvage: a case report
inferred← citeshttps://doi.org/10.13188/2332-4139.s100003openalex-snapshot
Mandible Reconstruction: A Review Article
inferred← citeshttps://doi.org/10.21037/gs.2019.08.08openalex-snapshot
Applications of rib sparing technique in internal mammary vessels exposure of abdominal free flap breast reconstructions: a 12-year single-center experience of 215 cases
inferred← citeshttps://doi.org/10.21294/1814-4861-2022-21-6-114-123openalex-snapshot
Planning of maxillofacial reconstruction with free revascularized fbular autograft: past, present, and future: literary review
inferred← citeshttps://doi.org/10.2152/jmi.61.318openalex-snapshot
Three-dimensional sodium chloride (NaCl) model for simulated mandibular reconstruction surgery: a new environmentally friendly material
inferred← citeshttps://doi.org/10.3390/diseases13030081openalex-snapshot
Evaluating Osteotomy Accuracy in Mandibular Reconstruction: A Preliminary Study Using Custom Cutting Guides and Virtual Reality
inferred← citeshttps://doi.org/10.3390/jcm12175526openalex-snapshot
Full Digital Workflow for Mandibular Ameloblastoma Management: Showcase for Technical Description
inferred← citeshttps://doi.org/10.3390/jcm15176819openalex-snapshot
Is the Arterial Anastomosis Time a Key Predictor of Free Flap Failure in Oncological Head and Neck Reconstruction? A Prospective Cohort Study
inferred← citeshttps://doi.org/10.4103/tjps.tjps_31_20openalex-snapshot
Comparing Venous Thrombosis Rates in Hand-Sewn Anastomosis to Anastomotic Coupler Devices
inferred← citeshttps://doi.org/10.4317/medoral.22336openalex-snapshot
Advantages of surgical simulation in the surgical reconstruction of oncological patients
inferred← citeshttps://doi.org/10.5177/ntvt.2013.09.12261openalex-snapshot
Driedimensionale technologie en reconstructies van grote kaakdefecten
inferred← citeshttps://doi.org/10.5772/63205openalex-snapshot
Computer-Aided Designed/Computer-Aided Manufactured and Conventional Techniques in Maxillofacial Reconstruction with Free Fibula Flaps
inferred← citeshttps://doi.org/10.5772/intechopen.112993openalex-snapshot
Advances in Ischemia Reperfusion Injury Prevention in Free Flaps and Vascularized Composite Allotransplantation
inferred← citeshttps://doi.org/10.7759/cureus.64467openalex-snapshot
The Microvascular Anastomotic Coupler for Venous Anastomosis in Head and Neck Reconstruction: An Institutional Experience
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