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Droplet-based microfluidics for artificial cell generation: a brief review
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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A Generalized System for Photoresponsive Membrane Rupture in Polymersomes
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Design of Vesicles Using Capillary Microfluidic Devices: From Magnetic to Multifunctional Vesicles
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Detection and Analysis of Low‐Abundance Cell‐Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets
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Multicompartment Polymersomes from Double Emulsions
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Generation of Monodisperse Particles by Using Microfluidics: Control over Size, Shape, and Composition
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Controllable Monodisperse Multiple Emulsions
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Detection and Analysis of Low‐Abundance Cell‐Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets
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Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology
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Multicompartment Polymersomes from Double Emulsions
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Protein Expression, Aggregation, and Triggered Release from Polymersomes as Artificial Cell‐like Structures
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Cascade Reactions in Multicompartmentalized Polymersomes
inferredcites →https://doi.org/10.1002/anie.201502886openalex-snapshot
Microfluidic Formation of Membrane‐Free Aqueous Coacervate Droplets in Water
inferredcites →https://doi.org/10.1002/anie.201506585openalex-snapshot
The Origin of Life—Out of the Blue
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Building artificial cells and protocell models: Experimental approaches with lipid vesicles
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Preparation, stability, and in vitro performance of vesicles made with diblock copolymers
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A New Embedded Process for Compartmentalized Cell‐Free Protein Expression and On‐line Detection in Microfluidic Devices
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An Integrated Device for Monitoring Time‐Dependent in vitro Expression From Single Genes in Picolitre Droplets
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Reconstitution and Anchoring of Cytoskeleton inside Giant Unilamellar Vesicles
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Giant Vesicles: Preparations and Applications
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Cytoskeletal Protein Expression and its Association within the Hydrophobic Membrane of Artificial Cell Models
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Enzyme synthesis and activity assay in microfluidic droplets on a chip
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A novel method for the preparation of liposomes: Freeze drying of monophase solutions
inferredcites →https://doi.org/10.1002/smll.201000798openalex-snapshot
Fabrication of Polymersomes using Double‐Emulsion Templates in Glass‐Coated Stamped Microfluidic Devices
inferredcites →https://doi.org/10.1002/smll.201201709openalex-snapshot
Polymersomes Containing a Hydrogel Network for High Stability and Controlled Release
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Ultrathin Shell Double Emulsion Templated Giant Unilamellar Lipid Vesicles with Controlled Microdomain Formation
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Microfluidic Droplet Manipulations and Their Applications
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Advances in Transport Phenomena 2011
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Microfluidic Fabrication of Vesicles
inferredcites →https://doi.org/10.1007/s00216-011-4984-5openalex-snapshot
Droplet microfluidics for the study of artificial cells
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Engineering artificial cells by combining HeLa-based cell-free expression and ultrathin double emulsion template
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Reconstitution of an Actin Cortex Inside a Liposome
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Integration of biological parts toward the synthesis of a minimal cell
inferredcites →https://doi.org/10.1016/j.copbio.2010.06.008openalex-snapshot
Update on designing and building minimal cells
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Towards an artificial cell
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Biodegradable polymersomes as a basis for artificial cells: encapsulation, release and targeting
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Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization
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Artificial cells: building bioinspired systems using small-scale biology
inferredcites →https://doi.org/10.1016/s0006-3495(04)74277-0openalex-snapshot
Giant Lipid Vesicles Filled with a Gel: Shape Instability Induced by Osmotic Shrinkage
inferredcites →https://doi.org/10.1016/s0076-6879(09)65007-2openalex-snapshot
Microfluidic Methods for Production of Liposomes
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Artificial cells: prospects for biotechnology
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Biotechnology Annual Review
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Artificial cells with emphasis on bioencapsulation in biotechnology
inferredcites →https://doi.org/10.1021/ac0480850openalex-snapshot
Selective Encapsulation of Single Cells and Subcellular Organelles into Picoliter- and Femtoliter-Volume Droplets
inferredcites →https://doi.org/10.1021/ac0613479openalex-snapshot
Lipid Bilayer Formation by Contacting Monolayers in a Microfluidic Device for Membrane Protein Analysis
inferredcites →https://doi.org/10.1021/ac200876qopenalex-snapshot
Intracellular Protein Determination Using Droplet-Based Immunoassays
inferredcites →https://doi.org/10.1021/ac802038copenalex-snapshot
Continuous-Flow Polymerase Chain Reaction of Single-Copy DNA in Microfluidic Microdroplets
inferredcites →https://doi.org/10.1021/ja056641hopenalex-snapshot
Controlled Microfluidic Encapsulation of Cells, Proteins, and Microbeads in Lipid Vesicles
inferredcites →https://doi.org/10.1021/ja109137sopenalex-snapshot
Stepwise Synthesis of Giant Unilamellar Vesicles on a Microfluidic Assembly Line
inferredcites →https://doi.org/10.1021/ja205687kopenalex-snapshot
Multiple Polymersomes for Programmed Release of Multiple Components
inferredcites →https://doi.org/10.1021/ja802157yopenalex-snapshot
Microfluidic Fabrication of Monodisperse Biocompatible and Biodegradable Polymersomes with Controlled Permeability
inferredcites →https://doi.org/10.1021/la0480336openalex-snapshot
Controlled Production of Monodisperse Double Emulsions by Two-Step Droplet Breakup in Microfluidic Devices
inferredcites →https://doi.org/10.1021/la1017032openalex-snapshot
Tunable Leuko-polymersomes That Adhere Specifically to Inflammatory Markers
inferredcites →https://doi.org/10.1021/la201604zopenalex-snapshot
Encapsulation of Active Cytoskeletal Protein Networks in Cell-Sized Liposomes
inferredcites →https://doi.org/10.1021/la801833aopenalex-snapshot
Double Emulsion Templated Monodisperse Phospholipid Vesicles
inferredcites →https://doi.org/10.1021/sb200003vopenalex-snapshot
Assembly of MreB Filaments on Liposome Membranes: A Synthetic Biology Approach
inferredcites →https://doi.org/10.1038/nature05058openalex-snapshot
The origins and the future of microfluidics
inferredcites →https://doi.org/10.1038/nbt0798-652openalex-snapshot
Man-made cell-like compartments for molecular evolution
inferredcites →https://doi.org/10.1038/nchem.1127openalex-snapshot
Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA
inferredcites →https://doi.org/10.1038/nchem.1765openalex-snapshot
Layer-by-layer cell membrane assembly
inferredcites →https://doi.org/10.1038/nchem.1921openalex-snapshot
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model
inferredcites →https://doi.org/10.1038/ncomms3494openalex-snapshot
Darwinian evolution in a translation-coupled RNA replication system within a cell-like compartment
inferredcites →https://doi.org/10.1038/ncomms5012openalex-snapshot
Integrating artificial with natural cells to translate chemical messages that direct E. coli behaviour
inferredcites →https://doi.org/10.1038/ncomms6305openalex-snapshot
Vesicle-based artificial cells as chemical microreactors with spatially segregated reaction pathways
inferredcites →https://doi.org/10.1038/nrd1659openalex-snapshot
Therapeutic applications of polymeric artificial cells
inferredcites →https://doi.org/10.1039/b605165kopenalex-snapshot
Biomimetic membranes designed from amphiphilic block copolymers
inferredcites →https://doi.org/10.1039/b616252eopenalex-snapshot
Miniaturizing chemistry and biology in microdroplets
inferredcites →https://doi.org/10.1039/b710474jopenalex-snapshot
Responsive viscoelastic giant lipid vesicles filled with a poly(N-isopropylacrylamide) artificial cytoskeleton
inferredcites →https://doi.org/10.1039/b806405aopenalex-snapshot
Microdroplets: A sea of applications?
inferredcites →https://doi.org/10.1039/b812388hopenalex-snapshot
Self-assembly approaches for the construction of cell architecture mimics
inferredcites →https://doi.org/10.1039/b820557bopenalex-snapshot
Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications
inferredcites →https://doi.org/10.1039/c004046kopenalex-snapshot
Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
inferredcites →https://doi.org/10.1039/c1cs15211dopenalex-snapshot
Designs for life: protocell models in the laboratory
inferredcites →https://doi.org/10.1039/c2an35047eopenalex-snapshot
Expression of membrane-associated proteins within single emulsion cell facsimiles
inferredcites →https://doi.org/10.1039/c2lc41121kopenalex-snapshot
Microfluidic methods for forming liposomes
inferredcites →https://doi.org/10.1039/c4lc00199kopenalex-snapshot
Integrating microfluidic generation, handling and analysis of biomimetic giant unilamellar vesicles
inferredcites →https://doi.org/10.1039/c5lc01150gopenalex-snapshot
Controllable generation and encapsulation of alginate fibers using droplet-based microfluidics
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Artificial Cells with Emphasis on Cell Encapsulation of Genetically Engineered Cells
inferredcites →https://doi.org/10.1063/1.4914112openalex-snapshot
Microfluidic generation of PEG-b-PLA polymersomes containing alginate-based core hydrogel
inferredcites →https://doi.org/10.1073/pnas.0408236101openalex-snapshot
A vesicle bioreactor as a step toward an artificial cell assembly
inferredcites →https://doi.org/10.1073/pnas.0710875105openalex-snapshot
Unilamellar vesicle formation and encapsulation by microfluidic jetting
inferredcites →https://doi.org/10.1073/pnas.1931005100openalex-snapshot
Engineering asymmetric vesicles
inferredcites →https://doi.org/10.1088/0960-1317/18/6/065018openalex-snapshot
Controlled double emulsification utilizing 3D PDMS microchannels
inferredcites →https://doi.org/10.1098/rsif.2009.0083.focusopenalex-snapshot
Opportunities for microfluidic technologies in synthetic biology
inferredcites →https://doi.org/10.1103/physrevlett.86.4163openalex-snapshot
Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device
inferredcites →https://doi.org/10.1111/j.1525-1594.2004.47343.xopenalex-snapshot
Artificial Cells for Cell and Organ Replacements
inferredcites →https://doi.org/10.1126/science.1109164openalex-snapshot
Monodisperse Double Emulsions Generated from a Microcapillary Device
inferredcites →https://doi.org/10.1126/science.146.3643.524openalex-snapshot
Semipermeable Microcapsules
inferredcites →https://doi.org/10.1126/science.284.5417.1143openalex-snapshot
Polymersomes: Tough Vesicles Made from Diblock Copolymers
inferredcites →https://doi.org/10.1529/biophysj.104.048876openalex-snapshot
Particle Size Distribution in DMPC Vesicles Solutions Undergoing Different Sonication Times
inferredcites →https://doi.org/10.2217/nnm.15.110openalex-snapshot
Polymersomes and their Applications in Cancer Delivery and Therapy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Microfluidic Handling and Analysis of Giant Vesicles for Use as Artificial Cells: A Review
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Self‐Assembly of Giant Unilamellar Vesicles by Film Hydration Methodologies
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Mimicking Cellular Signaling Pathways within Synthetic Multicompartment Vesicles with Triggered Enzyme Activity and Induced Ion Channel Recruitment
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Engineering Liver Microtissues for Disease Modeling and Regenerative Medicine
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Functional Integration of Synthetic Cells into 3D Microfluidic Devices for Artificial Organ‐On‐Chip Technologies
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Interface Engineering in Multiphase Systems toward Synthetic Cells and Organelles: From Soft Matter Fundamentals to Biomedical Applications
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Anisotropic Microcarriers: Fabrication Strategies and Biomedical Applications
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Generating Power Through Salinity Gradients in Osmotic Engines via Microfluidic Synthesized Hydrogel Particles
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MaxSynBio: Wege zur Synthese einer Zelle aus nicht lebenden Komponenten
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Cell‐free protein synthesis: The transition from batch reactions to minimal cells and microfluidic devices
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Comparison of Storage Methods for Microfluidically Produced Water‐in‐Oil Droplets
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Gene Expression Inside Liposomes: From Early Studies to Current Protocols
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Establishing Communication Between Artificial Cells
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Microfluidic production of monodisperse food‐additive polymer capsules for biological applications
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Recent Advances in Complex Coacervation Design from Macromolecular Assemblies and Emerging Applications
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XPORT ENTRAP: A droplet microfluidic platform for enhanced DNA transfer between microbial species
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Recent advances of droplet-based microfluidics for engineering artificial cells
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Multiscale modeling of food thermal processing for insight, comprehension, and utilization of heat and mass transfer: A state-of-the-art review
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Building Dynamic Cellular Machineries in Droplet-Based Artificial Cells with Single-Droplet Tracking and Analysis
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Passive Single-Chamber Micromixer with High Throughput and Low-Pressure Drop
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Polymerization-Induced Proteinosome Formation Initiated by Artificial Cells
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A Microfluidic Platform for Sequential Assembly and Separation of Synthetic Cell Models
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Actinosomes: Condensate-Templated Containers for Engineering Synthetic Cells
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Microfluidics-Based Engineering of Molecular Self-Assembly and Manufacturing for Artificial Cell Systems
inferred← citeshttps://doi.org/10.1021/acssynbio.7b00460openalex-snapshot
Deformation Modes of Giant Unilamellar Vesicles Encapsulating Biopolymers
inferred← citeshttps://doi.org/10.1021/acssynbio.8b00104openalex-snapshot
Live Follow-Up of Enzymatic Reactions Inside the Cavities of Synthetic Giant Unilamellar Vesicles Equipped with Membrane Proteins Mimicking Cell Architecture
inferred← citeshttps://doi.org/10.1021/acssynbio.9b00338openalex-snapshot
Artificial Cells Capable of Long-Lived Protein Synthesis by Using Aptamer Grafted Polymer Hydrogel
inferred← citeshttps://doi.org/10.1021/jacs.0c12494openalex-snapshot
Giant Coacervate Vesicles As an Integrated Approach to Cytomimetic Modeling
inferred← citeshttps://doi.org/10.1021/jacs.4c00860openalex-snapshot
A Chemical Reaction Network Drives Complex Population Dynamics in Oscillating Self-Reproducing Vesicles
inferred← citeshttps://doi.org/10.1038/nmat5005openalex-snapshot
Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics
inferred← citeshttps://doi.org/10.1038/s41378-022-00381-3openalex-snapshot
Pico-washing: simultaneous liquid addition and removal for continuous-flow washing of microdroplets
inferred← citeshttps://doi.org/10.1038/s41467-020-20124-0openalex-snapshot
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
inferred← citeshttps://doi.org/10.1038/s41596-025-01148-6openalex-snapshot
Construction of complex bacteriogenic protocells from living material assembly
inferred← citeshttps://doi.org/10.1038/s42005-024-01805-4openalex-snapshot
Droplets can enhance microcapsule deformation in channel flow
inferred← citeshttps://doi.org/10.1039/c6nr07807aopenalex-snapshot
Droplet-microfluidics towards the assembly of advanced building blocks in cell mimicry
inferred← citeshttps://doi.org/10.1039/c7lc00576hopenalex-snapshot
Droplet microfluidics for synthetic biology
inferred← citeshttps://doi.org/10.1039/c7sm01068kopenalex-snapshot
Mixed emulsion of liquid crystal microresonators: towards white laser systems
inferred← citeshttps://doi.org/10.1039/c8cs00162fopenalex-snapshot
Liposomes and polymersomes: a comparative review towards cell mimicking
inferred← citeshttps://doi.org/10.1039/c8py00992aopenalex-snapshot
Giant polymersomes from non-assisted film hydration of phosphate-based block copolymers
inferred← citeshttps://doi.org/10.1039/c8sc00383aopenalex-snapshot
Long-lived protein expression in hydrogel particles: towards artificial cells
inferred← citeshttps://doi.org/10.1039/c8sm00700dopenalex-snapshot
Opposed flow focusing: evidence of a second order jetting transition
inferred← citeshttps://doi.org/10.1039/c9lc00774aopenalex-snapshot
Perpetual sedimentation for the continuous delivery of particulate suspensions
inferred← citeshttps://doi.org/10.1039/c9sm01669dopenalex-snapshot
Encapsulation of the cytoskeleton: towards mimicking the mechanics of a cell
inferred← citeshttps://doi.org/10.1039/d0lc00111bopenalex-snapshot
Coaxial oblique interface shearing: tunable generation and sorting of double emulsions for spatial gradient drug release
inferred← citeshttps://doi.org/10.1039/d0lc01044hopenalex-snapshot
Double emulsions with ultrathin shell by microfluidic step-emulsification
inferred← citeshttps://doi.org/10.1039/d1mh01431eopenalex-snapshot
Vesicle-based artificial cells: materials, construction methods and applications
inferred← citeshttps://doi.org/10.1039/d2lc00089jopenalex-snapshot
Chip assisted formation of phase-separated liposomes for reconstituting spatial protein–lipid interactions
inferred← citeshttps://doi.org/10.1039/d3lc00584dopenalex-snapshot
Alignment-free construction of double emulsion droplet generation devices incorporating surface wettability contrast
inferred← citeshttps://doi.org/10.1039/d3na00124eopenalex-snapshot
Charge controlled interactions between DNA-modified silica nanoparticles and fluorosurfactants in microfluidic water-in-oil droplets
inferred← citeshttps://doi.org/10.1039/d5an01087jopenalex-snapshot
Triggering isothermal exponential amplification of microRNA via liposome fusion
inferred← citeshttps://doi.org/10.1063/1.5108583openalex-snapshot
An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy
inferred← citeshttps://doi.org/10.1063/5.0016534openalex-snapshot
Cross-stream migration of droplets in a confined shear-thinning viscoelastic flow: Role of shear-thinning induced lift
inferred← citeshttps://doi.org/10.1063/5.0213376openalex-snapshot
Mechanism of temporal interface evolution and internal circulations during the droplet formation in a planar slit T-microchannel
inferred← citeshttps://doi.org/10.1080/01932691.2019.1679643openalex-snapshot
New insights into generation of highly controllable monodisperse high-throughput microdroplets in a T-junction microchannel with step structure
inferred← citeshttps://doi.org/10.1080/08982104.2024.2420337openalex-snapshot
Microfluidics-based stable production of monodisperse giant unilamellar vesicles by oil-phase removal from double emulsion
inferred← citeshttps://doi.org/10.1088/1361-6439/ab2377openalex-snapshot
Encapsulation of complex solutions using droplet microfluidics towards the synthesis of artificial cells
inferred← citeshttps://doi.org/10.1088/1361-6439/ac545fopenalex-snapshot
A perspective of active microfluidic platforms as an enabling tool for applications in other fields
inferred← citeshttps://doi.org/10.1088/1367-2630/acb37aopenalex-snapshot
Optically pumped magnetometer with high spatial resolution magnetic guide for the detection of magnetic droplets in a microfluidic channel
inferred← citeshttps://doi.org/10.1088/1758-5090/ac39a9openalex-snapshot
Droplet-based microfluidics in biomedical applications
inferred← citeshttps://doi.org/10.1093/synbio/ysy011openalex-snapshot
Extrinsic stochastic factors (solute partition) in gene expression inside lipid vesicles and lipid-stabilized water-in-oil droplets: a review
inferred← citeshttps://doi.org/10.1098/rsfs.2016.0034openalex-snapshot
Introduction to ‘Sensors in technology and nature’
inferred← citeshttps://doi.org/10.1098/rsfs.2018.0032openalex-snapshot
Liquid–liquid phase separation in artificial cells
inferred← citeshttps://doi.org/10.1109/jmems.2025.3530466openalex-snapshot
Electrofusion Device With High-Aspect-Ratio Electrodes for the Controlled Fusion of Lipid Vesicles
inferred← citeshttps://doi.org/10.1111/cpr.13161openalex-snapshot
Advances in single‐cell sequencing and its application to musculoskeletal system research
inferred← citeshttps://doi.org/10.1111/nyas.14042openalex-snapshot
What can we learn from the construction of in vitro replication systems?
inferred← citeshttps://doi.org/10.1162/artl_a_00255openalex-snapshot
Multi-Armed Droplets as Shape-Changing Protocells
inferred← citeshttps://doi.org/10.1177/1535370217711441openalex-snapshot
Artificial cell mimics as simplified models for the study of cell biology
inferred← citeshttps://doi.org/10.1186/s40580-018-0145-2openalex-snapshot
Dual-nozzle microfluidic droplet generator
inferred← citeshttps://doi.org/10.12688/openreseurope.14766.1openalex-snapshot
Stability characterization of microfluidics lipid-stabilized double emulsions under physiologically-relevant conditions
inferred← citeshttps://doi.org/10.1364/oe.459332openalex-snapshot
Laser processing of microdroplet structure of liquid crystal in 3D
inferred← citeshttps://doi.org/10.1364/oe.496888openalex-snapshot
Fabrication and mechanical characterization of hydrogel-based 3D cell-like structures
inferred← citeshttps://doi.org/10.1557/s43579-020-00002-yopenalex-snapshot
Double-emulsion templated lipid vesicles as minimal cell mimics for assembling tissue-like vesicular materials
inferred← citeshttps://doi.org/10.33380/2305-2066-2022-11-2-79-86openalex-snapshot
Flow Dispersion for Obtaining Ivermectin Encapsulated in Polycaprolactone Microparticles
inferred← citeshttps://doi.org/10.3389/fmolb.2021.781986openalex-snapshot
Modularize and Unite: Toward Creating a Functional Artificial Cell
inferred← citeshttps://doi.org/10.3389/fsybi.2024.1397533openalex-snapshot
A comprehensive review of Microfluidic approaches in cell-free synthetic biology
inferred← citeshttps://doi.org/10.3390/books978-3-03842-619-6openalex-snapshot
Microdevices and Microsystems for Cell Manipulation
inferred← citeshttps://doi.org/10.3390/cryst13040683openalex-snapshot
Laser Processing of Liquid Crystal Droplets with Diverse Internal Structures
inferred← citeshttps://doi.org/10.3390/mi10040216openalex-snapshot
Creation of Artificial Cell-Like Structures Promoted by Microfluidics Technologies
inferred← citeshttps://doi.org/10.3390/mi10050299openalex-snapshot
Microfluidics for Artificial Life: Techniques for Bottom-Up Synthetic Biology
inferred← citeshttps://doi.org/10.3390/mi10090613openalex-snapshot
Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application
inferred← citeshttps://doi.org/10.3390/mi8040094openalex-snapshot
Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
inferred← citeshttps://doi.org/10.3390/mi9090468openalex-snapshot
Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
inferred← citeshttps://doi.org/10.3390/mi9090469openalex-snapshot
Continuous Recirculation of Microdroplets in a Closed Loop Tailored for Screening of Bacteria Cultures
inferred← citeshttps://doi.org/10.3762/bjoc.13.164openalex-snapshot
A recursive microfluidic platform to explore the emergence of chemical evolution
inferred← citeshttps://doi.org/10.5281/zenodo.46054openalex-snapshot
Labor Laws Of The Republic Of Korea
inferred← citeshttps://doi.org/10.5772/intechopen.106796openalex-snapshot
Real-Time Tracking of Individual Droplets in Multiphase Microfluidics
inferred← citeshttps://doi.org/10.70675/06f1bb39z2176z4948z8e34z7d3bf06e383eopenalex-snapshot
Swimming water droplet in complex environment, confinement, gravity and collective effects.
inferred← citeshttps://doi.org/10.70675/2c3e7dd2z2caaz4285za676z1af7965f3cbeopenalex-snapshot
From structure to bioactivity : exploring confinement effects in multicompartment and multicomponent vesicles
inferred← citeshttps://doi.org/10.7498/aps.71.20220625openalex-snapshot
Laser micro/nanomachining technology for soft matter
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