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Ageing, TOR and amino acid restriction: a cross-tissue transcriptional network connects GATA factors to Drosophila longevity
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s00018-015-2120-yopenalex-snapshot
The impact of low-protein high-carbohydrate diets on aging and lifespan
inferredcites →https://doi.org/10.1016/j.arr.2012.05.003openalex-snapshot
Organ-specific mediation of lifespan extension: More than a gut feeling?
inferredcites →https://doi.org/10.1016/j.cell.2008.05.044openalex-snapshot
An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans
inferredcites →https://doi.org/10.1016/j.cell.2011.08.048openalex-snapshot
Altered Modes of Stem Cell Division Drive Adaptive Intestinal Growth
inferredcites →https://doi.org/10.1016/j.cell.2013.05.042openalex-snapshot
XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity
inferredcites →https://doi.org/10.1016/j.cell.2015.02.033openalex-snapshot
Putting the Balance Back in Diet
inferredcites →https://doi.org/10.1016/j.celrep.2013.04.001openalex-snapshot
Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila
inferredcites →https://doi.org/10.1016/j.celrep.2014.01.015openalex-snapshot
Cell-Nonautonomous Effects of dFOXO/DAF-16 in Aging
inferredcites →https://doi.org/10.1016/j.celrep.2014.11.038openalex-snapshot
Mapping Gene Regulatory Networks in Drosophila Eye Development by Large-Scale Transcriptome Perturbations and Motif Inference
inferredcites →https://doi.org/10.1016/j.celrep.2015.05.007openalex-snapshot
Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice
inferredcites →https://doi.org/10.1016/j.celrep.2015.06.009openalex-snapshot
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut
inferredcites →https://doi.org/10.1016/j.celrep.2015.08.004openalex-snapshot
Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality
inferredcites →https://doi.org/10.1016/j.cmet.2007.06.006openalex-snapshot
Increased Internal and External Bacterial Load during Drosophila Aging without Life-Span Trade-Off
inferredcites →https://doi.org/10.1016/j.cmet.2009.12.004openalex-snapshot
miR-200 De-FOGs Insulin Signaling
inferredcites →https://doi.org/10.1016/j.cmet.2011.06.013openalex-snapshot
Dietary Restriction and Aging: A Unifying Perspective
inferredcites →https://doi.org/10.1016/j.cmet.2011.09.013openalex-snapshot
Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog
inferredcites →https://doi.org/10.1016/j.cmet.2012.04.007openalex-snapshot
TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO
inferredcites →https://doi.org/10.1016/j.cmet.2012.12.013openalex-snapshot
Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators
inferredcites →https://doi.org/10.1016/j.cmet.2014.02.009openalex-snapshot
The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice
inferredcites →https://doi.org/10.1016/j.cub.2012.07.024openalex-snapshot
Ageing as a Risk Factor for Disease
inferredcites →https://doi.org/10.1016/j.devcel.2015.03.013openalex-snapshot
REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1
inferredcites →https://doi.org/10.1016/j.exger.2010.11.036openalex-snapshot
Role of TOR signaling in aging and related biological processes in Drosophila melanogaster
inferredcites →https://doi.org/10.1016/j.ibmb.2015.05.015openalex-snapshot
All for one and one for all: Regionalization of the Drosophila intestine
inferredcites →https://doi.org/10.1016/j.semcdb.2004.10.005openalex-snapshot
GATA factors in Drosophila heart and blood cell development
inferredcites →https://doi.org/10.1016/j.tcb.2013.09.002openalex-snapshot
Proteostasis and aging of stem cells
inferredcites →https://doi.org/10.1016/j.tcb.2014.03.003openalex-snapshot
Regulation of mTORC1 by amino acids
inferredcites →https://doi.org/10.1016/j.ydbio.2015.12.017openalex-snapshot
GATAe regulates intestinal stem cell maintenance and differentiation in Drosophila adult midgut
inferredcites →https://doi.org/10.1016/s0168-6445(02)00071-2openalex-snapshot
Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots
inferredcites →https://doi.org/10.1016/s0925-4773(96)00615-6openalex-snapshot
The serpent gene is necessary for progression through the early stages of fat-body development
inferredcites →https://doi.org/10.1038/msb.2011.36openalex-snapshot
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
inferredcites →https://doi.org/10.1038/nature01789openalex-snapshot
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/nature08619openalex-snapshot
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
inferredcites →https://doi.org/10.1038/nature16953openalex-snapshot
The sexual identity of adult intestinal stem cells controls organ size and plasticity
inferredcites →https://doi.org/10.1038/ncb3174openalex-snapshot
Haemocytes control stem cell activity in the Drosophila intestine
inferredcites →https://doi.org/10.1038/ncomms7846openalex-snapshot
Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3
inferredcites →https://doi.org/10.1038/nprot.2013.099openalex-snapshot
Count-based differential expression analysis of RNA sequencing data using R and Bioconductor
inferredcites →https://doi.org/10.1073/pnas.0403460101openalex-snapshot
Target of rapamycin-mediated amino acid signaling in mosquito anautogeny
inferredcites →https://doi.org/10.1073/pnas.0710787105openalex-snapshot
Lifespan and reproduction in Drosophila : New insights from nutritional geometry
inferredcites →https://doi.org/10.1073/pnas.1215849110openalex-snapshot
Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila
inferredcites →https://doi.org/10.1073/pnas.2235649100openalex-snapshot
RNA interference-mediated knockdown of a GATA factor reveals a link to anautogeny in the mosquito Aedes aegypti
inferredcites →https://doi.org/10.1074/jbc.m114.578708openalex-snapshot
A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis without Affecting Longevity in Drosophila
inferredcites →https://doi.org/10.1074/jbc.m500712200openalex-snapshot
Target of Rapamycin-dependent Activation of S6 Kinase Is a Central Step in the Transduction of Nutritional Signals during Egg Development in a Mosquito
inferredcites →https://doi.org/10.1074/jbc.m601517200openalex-snapshot
GATA Factor Translation Is the Final Downstream Step in the Amino Acid/Target-of-Rapamycin-mediated Vitellogenin Gene Expression in the Anautogenous Mosquito Aedes aegypti
inferredcites →https://doi.org/10.1093/gerona/62.10.1071openalex-snapshot
Optimization of Dietary Restriction Protocols in Drosophila
inferredcites →https://doi.org/10.1093/jn/10.1.63openalex-snapshot
The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size
inferredcites →https://doi.org/10.1093/nar/gks543openalex-snapshot
i-cisTarget: an integrative genomics method for the prediction of regulatory features and cis-regulatory modules
inferredcites →https://doi.org/10.1101/gad.1170904openalex-snapshot
Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification
inferredcites →https://doi.org/10.1109/tvcg.2014.2346248openalex-snapshot
UpSet: Visualization of Intersecting Sets
inferredcites →https://doi.org/10.1111/j.1440-169x.2005.00836.xopenalex-snapshot
GATA factors as key regulatory molecules in the development of Drosophila endoderm
inferredcites →https://doi.org/10.1111/j.1474-9726.2006.00251.xopenalex-snapshot
Trade‐offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFκB signaling
inferredcites →https://doi.org/10.1111/j.1474-9726.2008.00373.xopenalex-snapshot
Drosophila lifespan control by dietary restriction independent of insulin‐like signaling
inferredcites →https://doi.org/10.1111/j.1474-9726.2008.00400.xopenalex-snapshot
Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster
inferredcites →https://doi.org/10.1111/j.1474-9726.2008.00421.xopenalex-snapshot
Characterization of the Drosophila Gene‐Switch system in aging studies: a cautionary tale
inferredcites →https://doi.org/10.1111/j.1474-9726.2011.00707.xopenalex-snapshot
dFOXO‐independent effects of reduced insulin‐like signaling in Drosophila
inferredcites →https://doi.org/10.1126/science.1072387openalex-snapshot
hamlet , a Binary Genetic Switch Between Single- and Multiple- Dendrite Neuron Morphology
inferredcites →https://doi.org/10.1126/science.1098219openalex-snapshot
Long-Lived Drosophila with Overexpressed dFOXO in Adult Fat Body
inferredcites →https://doi.org/10.1128/mcb.15.12.6943openalex-snapshot
Regulation of Drosophila yolk protein Genes by an Ovary-Specific GATA Factor
inferredcites →https://doi.org/10.1128/mcb.21.1.164-174.2001openalex-snapshot
A Novel GATA Factor Transcriptionally Represses Yolk Protein Precursor Genes in the Mosquito Aedes aegypti via Interaction with the CtBP Corepressor
inferredcites →https://doi.org/10.1152/ajpgi.00119.2013openalex-snapshot
Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium
inferredcites →https://doi.org/10.1155/2015/835624openalex-snapshot
Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster
inferredcites →https://doi.org/10.1186/1471-2105-9-559openalex-snapshot
WGCNA: an R package for weighted correlation network analysis
inferredcites →https://doi.org/10.1186/1752-0509-1-54openalex-snapshot
Eigengene networks for studying the relationships between co-expression modules
inferredcites →https://doi.org/10.1186/gb-2013-14-4-r36openalex-snapshot
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1242/jeb.101725openalex-snapshot
Gut microbiota dictates the metabolic response ofDrosophilato diet
inferredcites →https://doi.org/10.1371/journal.pbio.0030223openalex-snapshot
Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila
inferredcites →https://doi.org/10.1371/journal.pgen.1001159openalex-snapshot
Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila
inferredcites →https://doi.org/10.1371/journal.pgen.1004619openalex-snapshot
Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster
inferredcites →https://doi.org/10.1371/journal.pgen.1005265openalex-snapshot
The Developmental Intestinal Regulator ELT-2 Controls p38-Dependent Immune Responses in Adult C. elegans
inferredcites →https://doi.org/10.1371/journal.pone.0015171openalex-snapshot
The Drosophila FoxA Ortholog Fork Head Regulates Growth and Gene Expression Downstream of Target of Rapamycin
inferredcites →https://doi.org/10.1371/journal.pone.0074681openalex-snapshot
Dietary Restriction Extends Lifespan in Wild-Derived Populations of Drosophila melanogaster
inferredcites →https://doi.org/10.18632/aging.100665openalex-snapshot
Target of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration
inferredcites →https://doi.org/10.1891/0198-8794.34.243openalex-snapshot
Networks in the Biology of Aging: Powerful Tools for a Complex Process
inferredcites →https://doi.org/10.2307/2406060openalex-snapshot
Pleiotropy, Natural Selection, and the Evolution of Senescence
inferredcites →https://doi.org/10.7554/elife.10956openalex-snapshot
Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.bbadis.2017.09.016openalex-snapshot
Drosophila as a model for ageing
inferred← citeshttps://doi.org/10.1111/mec.14017openalex-snapshot
The genetic architecture of defence as resistance to and tolerance of bacterial infection in Drosophila melanogaster
inferred← citeshttps://doi.org/10.21315/mjms2020.27.3.2openalex-snapshot
Ageing, Drosophila melanogaster and Epigenetics
inferred← citeshttps://doi.org/10.3390/ijms19123810openalex-snapshot
Drosophila Gut—A Nexus Between Dietary Restriction and Lifespan
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