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PRDM9 forms a multiprotein complex tethering recombination hotspots to the chromosomal axis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/pmic.200600259openalex-snapshot
An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins
inferredcites →https://doi.org/10.1002/prot.22472openalex-snapshot
Crystal structures of human CDY proteins reveal a crotonase‐like fold
inferredcites →https://doi.org/10.1007/s00412-015-0511-3openalex-snapshot
Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis
inferredcites →https://doi.org/10.1007/s00439-011-1029-2openalex-snapshot
Evolutionary diversity and developmental regulation of X-chromosome inactivation
inferredcites →https://doi.org/10.1016/b978-0-12-394309-5.00005-5openalex-snapshot
Genetics of Meiosis and Recombination in Mice
inferredcites →https://doi.org/10.1016/j.celrep.2013.08.035openalex-snapshot
Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of PRDM9
inferredcites →https://doi.org/10.1016/j.molcel.2004.09.016openalex-snapshot
A Protein Interaction Network Links GIT1, an Enhancer of Huntingtin Aggregation, to Huntington's Disease
inferredcites →https://doi.org/10.1016/j.molcel.2008.10.025openalex-snapshot
CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation
inferredcites →https://doi.org/10.1016/j.molcel.2012.11.008openalex-snapshot
Spp1, a Member of the Set1 Complex, Promotes Meiotic DSB Formation in Promoters by Tethering Histone H3K4 Methylation Sites to Chromosome Axes
inferredcites →https://doi.org/10.1016/s0074-7696(02)17012-4openalex-snapshot
Regulation of nuclear import and export by the GTPase ran
inferredcites →https://doi.org/10.1023/a:1018445520117openalex-snapshot
SHORT COMMUNICATIONS A drying-down technique for the spreading of mammalian meiocytes from the male and female germline
inferredcites →https://doi.org/10.1038/emboj.2008.257openalex-snapshot
Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites
inferredcites →https://doi.org/10.1038/emboj.2009.207openalex-snapshot
Distinct histone modifications define initiation and repair of meiotic recombination in the mouse
inferredcites →https://doi.org/10.1038/nature04112openalex-snapshot
A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
inferredcites →https://doi.org/10.1038/nature09869openalex-snapshot
Genome-wide analysis reveals novel molecular features of mouse recombination hotspots
inferredcites →https://doi.org/10.1038/nature10336openalex-snapshot
The landscape of recombination in African Americans
inferredcites →https://doi.org/10.1038/nature11089openalex-snapshot
Genetic recombination is directed away from functional genomic elements in mice
inferredcites →https://doi.org/10.1038/nrg2712openalex-snapshot
Mammalian recombination hot spots: properties, control and evolution
inferredcites →https://doi.org/10.1038/nrg3573openalex-snapshot
Meiotic recombination in mammals: localization and regulation
inferredcites →https://doi.org/10.1038/sj.emboj.7601767openalex-snapshot
Functional dynamics of H3K9 methylation during meiotic prophase progression
inferredcites →https://doi.org/10.1051/medsci/201127163openalex-snapshot
Déterminants de la carte génétique
inferredcites →https://doi.org/10.1073/pnas.082248899openalex-snapshot
Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis
inferredcites →https://doi.org/10.1073/pnas.1014660108openalex-snapshot
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing
inferredcites →https://doi.org/10.1074/jbc.m111.271064openalex-snapshot
Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27
inferredcites →https://doi.org/10.1074/jbc.m508312200openalex-snapshot
CpG-binding Protein (CXXC Finger Protein 1) Is a Component of the Mammalian Set1 Histone H3-Lys4 Methyltransferase Complex, the Analogue of the Yeast Set1/COMPASS Complex
inferredcites →https://doi.org/10.1101/gad.1284005openalex-snapshot
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9
inferredcites →https://doi.org/10.1101/gad.237313.113openalex-snapshot
Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes
inferredcites →https://doi.org/10.1101/gad.274928.115openalex-snapshot
Structural basis for human PRDM9 action at recombination hot spots
inferredcites →https://doi.org/10.1101/gr.170167.113openalex-snapshot
PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration
inferredcites →https://doi.org/10.1111/his.12269openalex-snapshot
The diversity of soft tissue tumours with EWSR 1 gene rearrangements: a review
inferredcites →https://doi.org/10.1126/science.1181495openalex-snapshot
Prdm9 Controls Activation of Mammalian Recombination Hotspots
inferredcites →https://doi.org/10.1126/science.1182363openalex-snapshot
Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination
inferredcites →https://doi.org/10.1126/science.1183439openalex-snapshot
PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice
inferredcites →https://doi.org/10.1126/science.1225739openalex-snapshot
The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination
inferredcites →https://doi.org/10.1128/jvi.01006-12openalex-snapshot
EWSR1 Binds the Hepatitis C Virus cis -Acting Replication Element and Is Required for Efficient Viral Replication
inferredcites →https://doi.org/10.1128/mcb.00243-09openalex-snapshot
CXXC Finger Protein 1 Contains Redundant Functional Domains That Support Embryonic Stem Cell Cytosine Methylation, Histone Methylation, and Differentiation
inferredcites →https://doi.org/10.1128/mcb.00866-13openalex-snapshot
Cdyl, a New Partner of the Inactive X Chromosome and Potential Reader of H3K27me3 and H3K9me2
inferredcites →https://doi.org/10.1146/annurev-biochem-051710-134100openalex-snapshot
The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
inferredcites →https://doi.org/10.1146/annurev-biochem-060614-034325openalex-snapshot
Biochemical Properties and Biological Functions of FET Proteins
inferredcites →https://doi.org/10.1172/jci31222openalex-snapshot
Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development
inferredcites →https://doi.org/10.1186/1471-2148-7-187openalex-snapshot
Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates
inferredcites →https://doi.org/10.1186/gb-2005-6-8-227openalex-snapshot
The SET-domain protein superfamily: protein lysine methyltransferases.
inferredcites →https://doi.org/10.1186/gb-2013-14-4-r35openalex-snapshot
DNA binding specificities of the long zinc-finger recombination protein PRDM9
inferredcites →https://doi.org/10.1186/s13059-014-0451-xopenalex-snapshot
Cfp1 is required for gene expression-dependent H3K4 trimethylation and H3K9 acetylation in embryonic stem cells
inferredcites →https://doi.org/10.1186/s13072-015-0024-6openalex-snapshot
Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage
inferredcites →https://doi.org/10.1242/jcs.004945openalex-snapshot
Characterization ofSpo11-dependent and independent phospho-H2AX foci during meiotic prophase I in the male mouse
inferredcites →https://doi.org/10.1242/jcs.165464openalex-snapshot
MEI4: a central player in the regulation of meiotic DNA double strand break formation in the mouse
inferredcites →https://doi.org/10.1371/journal.pgen.1001134openalex-snapshot
Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
inferredcites →https://doi.org/10.1371/journal.pgen.1002485openalex-snapshot
Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis
inferredcites →https://doi.org/10.1371/journal.pgen.1004916openalex-snapshot
PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination
inferredcites →https://doi.org/10.1371/journal.pgen.1005512openalex-snapshot
Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots
inferredcites →https://doi.org/10.1371/journal.pgen.1006146openalex-snapshot
The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo
inferredcites →https://doi.org/10.2174/13892029113149990002openalex-snapshot
KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
inferredcites →https://doi.org/10.4161/cc.10.2.14543openalex-snapshot
Chromatin dynamics and the repair of DNA double strand breaks

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.7554/elife.24133openalex-snapshot
Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
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