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Frequency of mosaicism points towards mutation-prone early cleavage cell divisions in cattle

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2012.11.019openalex-snapshot
Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation
inferredcites →https://doi.org/10.1016/j.tig.2015.03.013openalex-snapshot
Somatic mosaicism: implications for disease and transmission genetics
inferredcites →https://doi.org/10.1038/437207aopenalex-snapshot
No hormonal response in tied fights
inferredcites →https://doi.org/10.1038/nature11396openalex-snapshot
Rate of de novo mutations and the importance of father’s age to disease risk
inferredcites →https://doi.org/10.1038/nature21703openalex-snapshot
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
inferredcites →https://doi.org/10.1038/nbt.1754openalex-snapshot
Integrative genomics viewer
inferredcites →https://doi.org/10.1038/ng.2418openalex-snapshot
Estimating the human mutation rate using autozygosity in a founder population
inferredcites →https://doi.org/10.1038/ng.3034openalex-snapshot
Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle
inferredcites →https://doi.org/10.1038/ng.3469openalex-snapshot
Timing, rates and spectra of human germline mutation
inferredcites →https://doi.org/10.1038/ng.862openalex-snapshot
Variation in genome-wide mutation rates within and between human families
inferredcites →https://doi.org/10.1038/s41467-019-12023-wopenalex-snapshot
Similarities and differences in patterns of germline mutation between mice and humans
inferredcites →https://doi.org/10.1046/j.1420-9101.1992.5030457.xopenalex-snapshot
Have premeiotic clusters of mutation been overlooked in evolutionary theory?
inferredcites →https://doi.org/10.1093/bioinformatics/btp324openalex-snapshot
Fast and accurate short read alignment with Burrows–Wheeler transform
inferredcites →https://doi.org/10.1093/genetics/163.1.453openalex-snapshot
Mosaicism of Solid Gold Supports the Causality of a Noncoding A-to-G Transition in the Determinism of the Callipyge Phenotype
inferredcites →https://doi.org/10.1098/rstb.2015.0137openalex-snapshot
Mutation rates and the evolution of germline structure
inferredcites →https://doi.org/10.1101/gr.107524.110openalex-snapshot
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
inferredcites →https://doi.org/10.1101/gr.204669.116openalex-snapshot
Direct estimate of the rate of germline mutation in a bird
inferredcites →https://doi.org/10.1126/science.1186802openalex-snapshot
Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
inferredcites →https://doi.org/10.1126/science.344.6189.1272openalex-snapshot
Strong male bias drives germline mutation in chimpanzees
inferredcites →https://doi.org/10.1146/annurev-genom-031714-125740openalex-snapshot
Determinants of Mutation Rate Variation in the Human Germline
inferredcites →https://doi.org/10.1186/1471-2105-9-253openalex-snapshot
BatchPrimer3: A high throughput web application for PCR and sequencing primer design
inferredcites →https://doi.org/10.48550/arxiv.1207.3907openalex-snapshot
Haplotype-based variant detection from short-read sequencing
inferredcites →https://doi.org/10.7554/elife.23907openalex-snapshot
Moderate nucleotide diversity in the Atlantic herring is associated with a low mutation rate

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/s11248-019-00141-6openalex-snapshot
Application of genome editing in farm animals: cattle
inferred← citeshttps://doi.org/10.1016/j.tig.2019.08.005openalex-snapshot
De Novo Mutations Reflect Development and Aging of the Human Germline
inferred← citeshttps://doi.org/10.1038/s41437-020-00383-9openalex-snapshot
An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree
inferred← citeshttps://doi.org/10.1038/s41437-021-00446-5openalex-snapshot
Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur
inferred← citeshttps://doi.org/10.1038/s41467-017-00323-yopenalex-snapshot
Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes
inferred← citeshttps://doi.org/10.1038/s41467-019-12023-wopenalex-snapshot
Similarities and differences in patterns of germline mutation between mice and humans
inferred← citeshttps://doi.org/10.1038/s41467-024-46434-1openalex-snapshot
GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle
inferred← citeshttps://doi.org/10.1038/s41467-026-70342-1openalex-snapshot
Long-read sequencing of families reveals increased germline and postzygotic mutation rates in repetitive DNA
inferred← citeshttps://doi.org/10.1038/s41538-019-0035-yopenalex-snapshot
Proposed U.S. regulation of gene-edited food animals is not fit for purpose
inferred← citeshttps://doi.org/10.1038/s41576-018-0082-2openalex-snapshot
Harnessing genomic information for livestock improvement
inferred← citeshttps://doi.org/10.1038/s41576-021-00376-2openalex-snapshot
The origin of human mutation in light of genomic data
inferred← citeshttps://doi.org/10.1038/s41586-023-05752-yopenalex-snapshot
Evolution of the germline mutation rate across vertebrates
inferred← citeshttps://doi.org/10.1038/s41587-019-0266-0openalex-snapshot
Genomic and phenotypic analyses of six offspring of a genome-edited hornless bull
inferred← citeshttps://doi.org/10.1038/s41588-018-0285-7openalex-snapshot
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations
inferred← citeshttps://doi.org/10.1038/s41588-020-00755-1openalex-snapshot
Differences between germline genomes of monozygotic twins
inferred← citeshttps://doi.org/10.1038/s42003-019-0476-5openalex-snapshot
Paternal exposure to benzo(a)pyrene induces genome-wide mutations in mouse offspring
inferred← citeshttps://doi.org/10.1073/pnas.1900714116openalex-snapshot
Signatures of replication timing, recombination, and sex in the spectrum of rare variants on the human X chromosome and autosomes
inferred← citeshttps://doi.org/10.1073/pnas.1901259116openalex-snapshot
Overlooked roles of DNA damage and maternal age in generating human germline mutations
inferred← citeshttps://doi.org/10.1073/pnas.1915664117openalex-snapshot
Changes in life history and population size can explain the relative neutral diversity levels on X and autosomes in extant human populations
inferred← citeshttps://doi.org/10.1093/evlett/qrad027openalex-snapshot
Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysis
inferred← citeshttps://doi.org/10.1093/genetics/iyac087openalex-snapshot
The impact of genetic modifiers on variation in germline mutation rates within and among human populations
inferred← citeshttps://doi.org/10.1093/genetics/iyae166openalex-snapshot
A maternal germline mutator phenotype in a family affected by heritable colorectal cancer
inferred← citeshttps://doi.org/10.1093/genetics/iyaf177openalex-snapshot
Low mutation rate but high male-bias in the germline of a short-lived opossum
inferred← citeshttps://doi.org/10.1093/molbev/msac134openalex-snapshot
Warthog Genomes Resolve an Evolutionary Conundrum and Reveal Introgression of Disease Resistance Genes
inferred← citeshttps://doi.org/10.1093/molbev/msac147openalex-snapshot
De novo Mutations in Domestic Cat are Consistent with an Effect of Reproductive Longevity on Both the Rate and Spectrum of Mutations
inferred← citeshttps://doi.org/10.1098/rstb.2015.0137openalex-snapshot
Mutation rates and the evolution of germline structure
inferred← citeshttps://doi.org/10.1101/2022.10.29.514266openalex-snapshot
Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.1101/2023.03.22.533860openalex-snapshot
Extensive variation in germline de novo mutations in Poecilia reticulata
inferred← citeshttps://doi.org/10.1101/2024.09.05.611523openalex-snapshot
Mutation and recombination parameters in zebra finch are similar to those in mammals
inferred← citeshttps://doi.org/10.1101/2024.12.13.628352openalex-snapshot
Unprecedented female mutation bias in aye-ayes
inferred← citeshttps://doi.org/10.1101/348441openalex-snapshot
Base pair editing of goat embryos: nonsense codon introgression into FGF5 to improve cashmere yield
inferred← citeshttps://doi.org/10.1101/gr.277884.123openalex-snapshot
The rate of de novo structural variation is increased in in vitro–produced offspring and preferentially affects the paternal genome
inferred← citeshttps://doi.org/10.1101/gr.277936.123openalex-snapshot
Extensive variation in germline de novo mutations in Poecilia reticulata
inferred← citeshttps://doi.org/10.1101/gr.279542.124openalex-snapshot
Overcoming limitations to customize DeepVariant for domesticated animals with TrioTrain
inferred← citeshttps://doi.org/10.1111/mec.16007openalex-snapshot
The challenge and promise of estimating the de novo mutation rate from whole‐genome comparisons among closely related individuals
inferred← citeshttps://doi.org/10.1126/science.adf2160openalex-snapshot
Wild pedigrees inform mutation rates and historic abundance in baleen whales
inferred← citeshttps://doi.org/10.1146/annurev-animal-050622-055534openalex-snapshot
Identification of Genetic Risk Factors for Monogenic and Complex Canine Diseases
inferred← citeshttps://doi.org/10.1186/s12711-017-0321-6openalex-snapshot
A strategy to improve phasing of whole-genome sequenced individuals through integration of familial information from dense genotype panels
inferred← citeshttps://doi.org/10.1186/s12711-025-00967-1openalex-snapshot
Estimating mutation rate and characterising single nucleotide de novo mutations in pigs
inferred← citeshttps://doi.org/10.1186/s12711-026-01085-2openalex-snapshot
The rate and spectrum of germline mutations in chicken from a commercial pedigree line
inferred← citeshttps://doi.org/10.1186/s12864-018-4712-zopenalex-snapshot
Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep
inferred← citeshttps://doi.org/10.1186/s12864-021-07804-xopenalex-snapshot
The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis
inferred← citeshttps://doi.org/10.1186/s12864-022-08354-6openalex-snapshot
Benchmarking phasing software with a whole-genome sequenced cattle pedigree
inferred← citeshttps://doi.org/10.1186/s12864-023-09296-3openalex-snapshot
Identification and characterisation of de novo germline structural variants in two commercial pig lines using trio-based whole genome sequencing
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000838openalex-snapshot
A comparison of humans and baboons suggests germline mutation rates do not track cell divisions
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003799openalex-snapshot
What sets the mutation rate of a cell type in an animal species?
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006651openalex-snapshot
A de novo variant in the ASPRV1 gene in a dog with ichthyosis
inferred← citeshttps://doi.org/10.1371/journal.pgen.1008055openalex-snapshot
Loss of function mutations in essential genes cause embryonic lethality in pigs
inferred← citeshttps://doi.org/10.1534/genetics.117.1114openalex-snapshot
Contrasting Determinants of Mutation Rates in Germline and Soma
inferred← citeshttps://doi.org/10.18174/515207openalex-snapshot
From sequence to phenotype: the impact of deleterious variation in livestock
inferred← citeshttps://doi.org/10.22215/etd/2017-11975openalex-snapshot
Harnessing New Genomics Technologies to Assess Environmental Risk Factors That May Cause Heritable Genetic Disease
inferred← citeshttps://doi.org/10.3389/fgene.2018.00449openalex-snapshot
Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats
inferred← citeshttps://doi.org/10.3389/fgene.2019.00215openalex-snapshot
Programmable Base Editing of the Sheep Genome Revealed No Genome-Wide Off-Target Mutations
inferred← citeshttps://doi.org/10.7554/elife.23907openalex-snapshot
Moderate nucleotide diversity in the Atlantic herring is associated with a low mutation rate
inferred← citeshttps://doi.org/10.7554/elife.46922openalex-snapshot
Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation
inferred← citeshttps://doi.org/10.7554/elife.73577openalex-snapshot
The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates
inferred← citeshttps://doi.org/10.7554/elife.80008openalex-snapshot
A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers
inferred← citeshttps://doi.org/10.7554/elife.84874openalex-snapshot
Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1openalex-snapshot
Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1.sa0openalex-snapshot
Author Response: Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1.sa1openalex-snapshot
Reviewer #3 (Public Review): Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1.sa2openalex-snapshot
Reviewer #2 (Public Review): Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1.sa3openalex-snapshot
Reviewer #1 (Public Review): Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.1.sa4openalex-snapshot
eLife Assessment: Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.2openalex-snapshot
Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
inferred← citeshttps://doi.org/10.7554/elife.84874.3openalex-snapshot
Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
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