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An agent-based model of dengue virus transmission shows how multiple uncertainties about vaccine efficacy influence public health impact projections

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial
inferredcites →https://doi.org/10.1016/s0140-6736(15)60889-3openalex-snapshot
Differential efficacy of dengue vaccine by immune status
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A mathematical model of the indirect effects of rotavirus vaccination
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Exact stochastic simulation of coupled chemical reactions
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Model-based projections of Zika virus infections in childbearing women in the Americas
inferredcites →https://doi.org/10.1038/nrmicro.2015.2openalex-snapshot
Dengue vaccine: hypotheses to understand CYD-TDV-induced protection
inferredcites →https://doi.org/10.1049/ip-f-2.1993.0015openalex-snapshot
Novel approach to nonlinear/non-Gaussian Bayesian state estimation
inferredcites →https://doi.org/10.1056/nejme1509442openalex-snapshot
A Candidate Dengue Vaccine Walks a Tightrope
inferredcites →https://doi.org/10.1056/nejmoa0805715openalex-snapshot
Zika Virus Outbreak on Yap Island, Federated States of Micronesia
inferredcites →https://doi.org/10.1056/nejmoa1506223openalex-snapshot
Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease
inferredcites →https://doi.org/10.1073/pnas.1303395110openalex-snapshot
Host and viral features of human dengue cases shape the population of infected and infectious Aedes aegypti mosquitoes
inferredcites →https://doi.org/10.1073/pnas.1314933111openalex-snapshot
Time-varying, serotype-specific force of infection of dengue virus
inferredcites →https://doi.org/10.1073/pnas.1508114112openalex-snapshot
Asymptomatic humans transmit dengue virus to mosquitoes
inferredcites →https://doi.org/10.1086/425271openalex-snapshot
Role of Herd Immunity in Determining the Effect of Vaccines against Sexually Transmitted Disease
inferredcites →https://doi.org/10.1086/511825openalex-snapshot
Natural History of Dengue Virus (DENV)–1 and DENV‐4 Infections: Reanalysis of Classic Studies
inferredcites →https://doi.org/10.1093/ije/6.3.259openalex-snapshot
Disease and Mobility: A Neglected Factor in Epidemiology
inferredcites →https://doi.org/10.1093/infdis/jit273openalex-snapshot
Reduced Risk of Disease During Postsecondary Dengue Virus Infections
inferredcites →https://doi.org/10.1093/infdis/jiw638openalex-snapshot
Dengue virus (DENV)-specific antibodies enhance Brazilian Zika virus (ZIKV) infection
inferredcites →https://doi.org/10.1093/jmedent/30.6.1003openalex-snapshot
Dynamic Life Table Model for Aedes aegypti (Diptera: Culicidae): Analysis of the Literature and Model Development
inferredcites →https://doi.org/10.1098/rsif.2013.0414openalex-snapshot
Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity
inferredcites →https://doi.org/10.1098/rsif.2014.0642openalex-snapshot
Theory and data for simulating fine-scale human movement in an urban environment
inferredcites →https://doi.org/10.1126/science.aaf8505openalex-snapshot
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
inferredcites →https://doi.org/10.1177/0272989x06290485openalex-snapshot
Impact of Model, Methodological, and Parameter Uncertainty in the Economic Analysis of Vaccination Programs
inferredcites →https://doi.org/10.1179/136485906x105534openalex-snapshot
Aedes aegypti (Diptera: Culicidae) production from non-residential sites in the Amazonian city of Iquitos, Peru
inferredcites →https://doi.org/10.1186/1471-2334-14-447openalex-snapshot
A spatial simulation model for dengue virus infection in urban areas
inferredcites →https://doi.org/10.1186/1756-3305-6-351openalex-snapshot
Modelling adult Aedes aegypti and Aedes albopictus survival at different temperatures in laboratory and field settings
inferredcites →https://doi.org/10.1201/9781420010404openalex-snapshot
Generalized Additive Models
inferredcites →https://doi.org/10.1371/journal.pmed.0050068openalex-snapshot
Defining Challenges and Proposing Solutions for Control of the Virus Vector Aedes aegypti
inferredcites →https://doi.org/10.1371/journal.pmed.1002181openalex-snapshot
The Long-Term Safety, Public Health Impact, and Cost-Effectiveness of Routine Vaccination with a Recombinant, Live-Attenuated Dengue Vaccine (Dengvaxia): A Model Comparison Study
inferredcites →https://doi.org/10.1371/journal.pntd.0000670openalex-snapshot
Epidemiology of Dengue Virus in Iquitos, Peru 1999 to 2005: Interepidemic and Epidemic Patterns of Transmission
inferredcites →https://doi.org/10.1371/journal.pntd.0001876openalex-snapshot
Controlling Dengue with Vaccines in Thailand
inferredcites →https://doi.org/10.1371/journal.pntd.0002126openalex-snapshot
Challenges in the Interpretation of Dengue Vaccine Trial Results
inferredcites →https://doi.org/10.1371/journal.pntd.0002702openalex-snapshot
Determinants of Heterogeneous Blood Feeding Patterns by Aedes aegypti in Iquitos, Peru
inferredcites →https://doi.org/10.1371/journal.pntd.0003003openalex-snapshot
Long-Term and Seasonal Dynamics of Dengue in Iquitos, Peru
inferredcites →https://doi.org/10.1371/journal.pntd.0003648openalex-snapshot
River Boats Contribute to the Regional Spread of the Dengue Vector Aedes aegypti in the Peruvian Amazon
inferredcites →https://doi.org/10.1371/journal.pntd.0003655openalex-snapshot
A Critical Assessment of Vector Control for Dengue Prevention
inferredcites →https://doi.org/10.1371/journal.pntd.0004398openalex-snapshot
Incomplete Protection against Dengue Virus Type 2 Re-infection in Peru
inferredcites →https://doi.org/10.1371/journal.pntd.0005926openalex-snapshot
Immune status alters the probability of apparent illness due to dengue virus infection: Evidence from a pooled analysis across multiple cohort and cluster studies
inferredcites →https://doi.org/10.1371/journal.pntd.0007255openalex-snapshot
Estimating the impact of city-wide Aedes aegypti population control: An observational study in Iquitos, Peru
inferredcites →https://doi.org/10.1371/journal.pone.0041720openalex-snapshot
Understanding Reduced Rotavirus Vaccine Efficacy in Low Socio-Economic Settings
inferredcites →https://doi.org/10.1371/journal.pone.0050972openalex-snapshot
The Incubation Periods of Dengue Viruses
inferredcites →https://doi.org/10.1586/eri.12.76openalex-snapshot
Diagnosis of dengue: an update
inferredcites →https://doi.org/10.1603/0022-2585-41.6.1123openalex-snapshot
Temporal and Geographic Patterns of Aedes aegypti (Diptera: Culicidae) Production in Iquitos, Peru
inferredcites →https://doi.org/10.3201/eid1009.030921openalex-snapshot
Potential Public Health Impact of New Tuberculosis Vaccines
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing
inferredcites →https://doi.org/10.3389/fimmu.2014.00280openalex-snapshot
Epidemiological Risk Factors Associated with High Global Frequency of Inapparent Dengue Virus Infections
inferredcites →https://doi.org/10.4269/ajtmh.1952.1.30openalex-snapshot
Research on Dengue during World War II
inferredcites →https://doi.org/10.4269/ajtmh.1989.40.418openalex-snapshot
An Enzyme-Linked Immunosorbent Assay to Characterize Dengue Infections Where Dengue and Japanese Encephalitis Co-Circulate
inferredcites →https://doi.org/10.4269/ajtmh.2003.69.494openalex-snapshot
CHARACTERISTICS OF THE SPATIAL PATTERN OF THE DENGUE VECTOR, AEDES AEGYPTI, IN IQUITOS, PERU
inferredcites →https://doi.org/10.4269/ajtmh.2005.72.209openalex-snapshot
DISPERSAL OF THE DENGUE VECTOR AEDES AEGYPTI WITHIN AND BETWEEN RURAL COMMUNITIES
inferredcites →https://doi.org/10.4269/ajtmh.2011.10-0516openalex-snapshot
Parameterization and Sensitivity Analysis of a Complex Simulation Model for Mosquito Population Dynamics, Dengue Transmission, and Their Control
inferredcites →https://doi.org/10.4269/ajtmh.2012.12-0157openalex-snapshot
The Economic Burden of Dengue

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/s40264-020-00984-7openalex-snapshot
Benefit–Risk Assessment of Vaccines. Part I: A Systematic Review to Identify and Describe Studies About Quantitative Benefit–Risk Models Applied to Vaccines
inferred← citeshttps://doi.org/10.1101/2025.10.11.25337791openalex-snapshot
Limitations of Disease X vaccine efficacy and safety clinical trials
inferred← citeshttps://doi.org/10.1109/wsc.2018.8632502openalex-snapshot
MODELING DISEASES: PREVENTION, CURE AND MANAGEMENT
inferred← citeshttps://doi.org/10.1371/journal.pmed.1002181openalex-snapshot
The Long-Term Safety, Public Health Impact, and Cost-Effectiveness of Routine Vaccination with a Recombinant, Live-Attenuated Dengue Vaccine (Dengvaxia): A Model Comparison Study
inferred← citeshttps://doi.org/10.1371/journal.pntd.0007482openalex-snapshot
Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure
inferred← citeshttps://doi.org/10.1371/journal.pone.0210041openalex-snapshot
Biased efficacy estimates in phase-III dengue vaccine trials due to heterogeneous exposure and differential detectability of primary infections across trial arms
inferred← citeshttps://doi.org/10.3410/f.734924980.793562691openalex-snapshot
Faculty Opinions recommendation of Biased efficacy estimates in phase-III dengue vaccine trials due to heterogeneous exposure and differential detectability of primary infections across trial arms.
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