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Identification of a novel, NF-κB nucleolar stress response pathway
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Outgoing claims: the papers this work cites, builds on, or argues with.
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The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy
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Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress
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TIF-IA: An oncogenic target of pre-ribosomal RNA synthesis
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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
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Ribosomal Protein S3: A KH Domain Subunit in NF-κB Complexes that Mediates Selective Gene Regulation
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Genetic Inactivation of the Transcription Factor TIF-IA Leads to Nucleolar Disruption, Cell Cycle Arrest, and p53-Mediated Apoptosis
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The Nucleolus under Stress
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Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity
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Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
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p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor
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CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response
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Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin
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The diverse and complex roles of NF-κB subunits in cancer
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Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway
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The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway
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Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib
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Aspirin-induced nuclear translocation of NFκB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency
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How NF-κB is activated: the role of the IκB kinase (IKK) complex
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Activators and target genes of Rel/NF-κB transcription factors
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Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes
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Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation
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Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA
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Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription
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Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
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Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
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UV-C Light Induces Raft-associated Acid Sphingomyelinase and JNK Activation and Translocation Independently on a Nuclear Signal
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A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage
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Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53
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Multiple interactions between RNA polymerase I, TIF‐IA and TAFI subunits regulate preinitiation complex assembly at the ribosomal gene promoter
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Phosphorylation by G1‐specific cdk–cyclin complexes activates the nucleolar transcription factor UBF
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Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
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Aspirin‐induced activation of the NF‐κB signaling pathway: a novel mechanism for aspirin‐mediated apoptosis in colon cancer cells
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NF-κB, the first quarter-century: remarkable progress and outstanding questions
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mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability
inferredcites →https://doi.org/10.1101/gad.333205openalex-snapshot
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis
inferredcites →https://doi.org/10.1111/j.1600-065x.2012.01099.xopenalex-snapshot
NF‐κB and the link between inflammation and cancer
inferredcites →https://doi.org/10.1111/j.1751-1097.2010.00767.xopenalex-snapshot
Differential Signaling Circuits in Regulation of Ultraviolet C Light‐induced Early‐ and Late‐phase Activation of NF‐κB
inferredcites →https://doi.org/10.1126/science.282.5393.1497openalex-snapshot
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
inferredcites →https://doi.org/10.1128/mcb.00492-08openalex-snapshot
Phosphorylation by Casein Kinase 2 Facilitates rRNA Gene Transcription by Promoting Dissociation of TIF-IA from Elongating RNA Polymerase I
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Mechanism of Repression of RNA Polymerase I Transcription by the Retinoblastoma Protein
inferredcites →https://doi.org/10.1128/mcb.23.16.5651-5663.2003openalex-snapshot
Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses
inferredcites →https://doi.org/10.1128/mcb.25.14.5985-6004.2005openalex-snapshot
Nucleolar Sequestration of RelA (p65) Regulates NF-κB-Driven Transcription and Apoptosis
inferredcites →https://doi.org/10.1136/gut.2009.203000openalex-snapshot
Effect of aspirin and NSAIDs on risk and survival from colorectal cancer
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p38-Mediated Inactivation of Cyclin D1/Cyclin-Dependent Kinase 4 Stimulates Nucleolar Translocation of RelA and Apoptosis in Colorectal Cancer Cells
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Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth
inferredcites →https://doi.org/10.1158/0008-5472.can-11-3992openalex-snapshot
Ribosome Biogenesis and Control of Cell Proliferation: p53 Is Not Alone
inferredcites →https://doi.org/10.1158/1535-7163.mct-14-0256openalex-snapshot
Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress
inferredcites →https://doi.org/10.1242/jcs.01224openalex-snapshot
Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-κB inducing kinase NIK
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Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles
inferredcites →https://doi.org/10.18632/oncotarget.2591openalex-snapshot
Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP
inferredcites →https://doi.org/10.3390/cells1040774openalex-snapshot
p53 -Dependent and -Independent Nucleolar Stress Responses
inferredcites →https://doi.org/10.3390/ijms18010140openalex-snapshot
Ribosomal Proteins Control or Bypass p53 during Nucleolar Stress
inferredcites →https://doi.org/10.4161/cc.4.8.1925openalex-snapshot
Cellular Stress and Nucleolar Function
inferredcites →https://doi.org/10.4161/cc.6.11.4312openalex-snapshot
CDK4 Inhibitors and Apoptosis: A Novel Mechanism Requiring Nucleolar Targeting of RelA
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Nucleolar stress with and without p53
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