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Collective effects of common SNPs and improved risk prediction in lung cancer

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Estimation of genetic and environmental components in colorectal and lung cancer and melanoma
inferredcites →https://doi.org/10.1002/ijc.10332openalex-snapshot
Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish family‐cancer database
inferredcites →https://doi.org/10.1002/sim.3859openalex-snapshot
Evaluating diagnostic tests: The area under the ROC curve and the balance of errors
inferredcites →https://doi.org/10.1007/s11427-014-4704-4openalex-snapshot
Scoring the collective effects of SNPs: association of minor alleles with complex traits in model organisms
inferredcites →https://doi.org/10.1007/s13277-013-1511-7openalex-snapshot
Collagen as a double-edged sword in tumor progression
inferredcites →https://doi.org/10.1016/0140-6736(90)90801-bopenalex-snapshot
Increased expression of mutant forms of p53 oncogene in primary lung cancer
inferredcites →https://doi.org/10.1016/b978-1-4160-4710-0.00046-8openalex-snapshot
Epidemiology of Lung Cancer
inferredcites →https://doi.org/10.1016/b978-1-4557-3383-5.00052-xopenalex-snapshot
Epidemiology of Lung Cancer
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A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma
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GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2011.05.003openalex-snapshot
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma
inferredcites →https://doi.org/10.1016/j.chembiol.2004.06.010openalex-snapshot
Purmorphamine Induces Osteogenesis by Activation of the Hedgehog Signaling Pathway
inferredcites →https://doi.org/10.1016/j.mrfmmm.2007.11.005openalex-snapshot
Correlating observed odds ratios from lung cancer case–control studies to SNP functional scores predicted by bioinformatic tools
inferredcites →https://doi.org/10.1016/j.ygeno.2016.01.008openalex-snapshot
New thoughts on an old riddle: What determines genetic diversity within and between species?
inferredcites →https://doi.org/10.1038/35074129openalex-snapshot
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
inferredcites →https://doi.org/10.1038/nature07423openalex-snapshot
Somatic mutations affect key pathways in lung adenocarcinoma
inferredcites →https://doi.org/10.1038/ng.109openalex-snapshot
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
inferredcites →https://doi.org/10.1038/ng.875openalex-snapshot
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese
inferredcites →https://doi.org/10.1038/npre.2008.1733.1openalex-snapshot
The genetic equidistance result of molecular evolution is independent of mutation rates
inferredcites →https://doi.org/10.1038/npre.2008.1751openalex-snapshot
Inverse relationship between genetic diversity and epigenetic complexity
inferredcites →https://doi.org/10.1038/npre.2009.1751.2openalex-snapshot
Inverse relationship between genetic diversity and epigenetic complexity
inferredcites →https://doi.org/10.1038/nprot.2008.211openalex-snapshot
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
inferredcites →https://doi.org/10.1038/nrc2521openalex-snapshot
Derailed endocytosis: an emerging feature of cancer
inferredcites →https://doi.org/10.1038/nrc2748openalex-snapshot
Integrins in cancer: biological implications and therapeutic opportunities
inferredcites →https://doi.org/10.1038/nrg3118openalex-snapshot
Rare and common variants: twenty arguments
inferredcites →https://doi.org/10.1038/sj.bjc.6604158openalex-snapshot
The LLP risk model: an individual risk prediction model for lung cancer
inferredcites →https://doi.org/10.1056/nejmoa0804742openalex-snapshot
Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/hmg/ddp295openalex-snapshot
Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk
inferredcites →https://doi.org/10.1093/hmg/ddr116openalex-snapshot
Improved risk prediction for Crohn's disease with a multi-locus approach
inferredcites →https://doi.org/10.1093/hmg/ddr378openalex-snapshot
Genetic risk prediction in complex disease
inferredcites →https://doi.org/10.1093/jnci/djk153openalex-snapshot
A Risk Model for Prediction of Lung Cancer
inferredcites →https://doi.org/10.1093/jnci/djn215openalex-snapshot
Gauging the Performance of SNPs, Biomarkers, and Clinical Factors for Predicting Risk of Breast Cancer
inferredcites →https://doi.org/10.1093/nar/27.1.29openalex-snapshot
KEGG: Kyoto Encyclopedia of Genes and Genomes
inferredcites →https://doi.org/10.1093/nar/28.1.27openalex-snapshot
KEGG: Kyoto Encyclopedia of Genes and Genomes
inferredcites →https://doi.org/10.1093/nar/gkq603openalex-snapshot
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
inferredcites →https://doi.org/10.1097/jto.0000000000000666openalex-snapshot
Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions
inferredcites →https://doi.org/10.1101/101410openalex-snapshot
Modern human origins: multiregional evolution of autosomes and East Asia origin of Y and mtDNA
inferredcites →https://doi.org/10.1101/cshperspect.a016949openalex-snapshot
Endocytosis and Cancer
inferredcites →https://doi.org/10.1126/science.1099314openalex-snapshot
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
inferredcites →https://doi.org/10.1126/science.2554494openalex-snapshot
p53: A Frequent Target for Genetic Abnormalities in Lung Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-14-2101openalex-snapshot
Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
inferredcites →https://doi.org/10.1186/1471-2350-13-118openalex-snapshot
Prediction of lung cancer risk in a Chinese population using a multifactorial genetic model
inferredcites →https://doi.org/10.1186/1475-4924-1-10openalex-snapshot
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
inferredcites →https://doi.org/10.1242/dmm.004077openalex-snapshot
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
inferredcites →https://doi.org/10.1371/journal.pone.0133421openalex-snapshot
Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease
inferredcites →https://doi.org/10.1517/phgs.4.4.411.22751openalex-snapshot
The Hedgehog signaling pathway – implications for drug targets in cancer and neurodegenerative disorders
inferredcites →https://doi.org/10.4065/83.5.584openalex-snapshot
Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
inferredcites →https://doi.org/10.4172/jcsb.1000009openalex-snapshot
The Genetic Equidistance Result of Molecular Evolution is Independent of Mutation Rates
inferredcites →https://doi.org/10.48550/arxiv.1209.2911openalex-snapshot
Methods for scoring the collective effect of SNPs: Minor alleles of common SNPs quantitatively affect traits/diseases and are under both positive and negative selection

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/130989openalex-snapshot
On the peopling of the Americas: molecular evidence for the Paleoamerican and the Solutrean models
inferred← citeshttps://doi.org/10.1101/2020.03.10.986042openalex-snapshot
Ancient Y chromosomes confirm origin of modern human paternal lineages in Asia rather than Africa
inferred← citeshttps://doi.org/10.1101/487918openalex-snapshot
Ancient DNAs and the Neolithic Chinese super-grandfather Y haplotypes
inferred← citeshttps://doi.org/10.1101/546234openalex-snapshot
The Out of East Asia model versus the African Eve model of modern human origins in light of ancient mtDNA findings
inferred← citeshttps://doi.org/10.1101/821736openalex-snapshot
Testing the basic tenet of the molecular clock and neutral theory by using ancient proteomes
inferred← citeshttps://doi.org/10.1111/cge.13193openalex-snapshot
Collective effects of common single nucleotide polymorphisms and genetic risk prediction in type 1 diabetes
inferred← citeshttps://doi.org/10.1371/journal.pone.0187644openalex-snapshot
Enrichment of minor allele of SNPs and genetic prediction of type 2 diabetes risk in British population
inferred← citeshttps://doi.org/10.21203/rs.2.10181/v1openalex-snapshot
Ancient DNAs and the Neolithic Chinese super-grandfather Y haplotypes
inferred← citeshttps://doi.org/10.4310/cis.2019.v19.n3.a6openalex-snapshot
Enrichment of de novo mutations in non-SNP sites in autism spectrum disorders and an empirical test of the neutral DNA model
inferred← citeshttps://doi.org/10.4310/cis.2019.v19.n4.a1openalex-snapshot
Genetic continuity in the last seven Millennia in human hepatitis B viruses
inferred← citeshttps://doi.org/10.7717/peerj.9983openalex-snapshot
Enrichment in conservative amino acid changes among fixed and standing missense variations in slowly evolving proteins
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