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Integrative cross tissue analysis of gene expression identifies novel type 2 diabetes genes
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/978-0-387-84858-7openalex-snapshot
The Elements of Statistical Learning: Data Mining, Inference, and Prediction
inferredcites →https://doi.org/10.1007/s00125-011-2172-yopenalex-snapshot
Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas
inferredcites →https://doi.org/10.1007/s11248-011-9537-3openalex-snapshot
The construction of transgenic and gene knockout/knockin mouse models of human disease
inferredcites →https://doi.org/10.1016/j.ajhg.2011.11.029openalex-snapshot
Five Years of GWAS Discovery
inferredcites →https://doi.org/10.1016/j.ajhg.2012.08.002openalex-snapshot
Genetic Risk Factors for Type 2 Diabetes: A Trans-Regulatory Genetic Architecture?
inferredcites →https://doi.org/10.1016/j.ajhg.2014.10.001openalex-snapshot
Cross-Tissue and Tissue-Specific eQTLs: Partitioning the Heritability of a Complex Trait
inferredcites →https://doi.org/10.1016/j.ajhg.2014.10.004openalex-snapshot
Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
inferredcites →https://doi.org/10.1016/j.ajhg.2015.11.020openalex-snapshot
Genotype Imputation with Millions of Reference Samples
inferredcites →https://doi.org/10.1016/j.pharmthera.2005.03.004openalex-snapshot
RNA interference: From gene silencing to gene-specific therapeutics
inferredcites →https://doi.org/10.1016/j.ydbio.2005.06.024openalex-snapshot
sox4b is a key player of pancreatic α cell differentiation in zebrafish
inferredcites →https://doi.org/10.1016/j.ygeno.2011.04.005openalex-snapshot
Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array
inferredcites →https://doi.org/10.1016/j.ygeno.2011.08.007openalex-snapshot
Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
inferredcites →https://doi.org/10.1038/75556openalex-snapshot
Gene Ontology: tool for the unification of biology
inferredcites →https://doi.org/10.1038/ejhg.2016.17openalex-snapshot
Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility
inferredcites →https://doi.org/10.1038/nature09266openalex-snapshot
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
inferredcites →https://doi.org/10.1038/nature10808openalex-snapshot
DNase I sensitivity QTLs are a major determinant of human expression variation
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nature13138openalex-snapshot
Obesity-associated variants within FTO form long-range functional connections with IRX3
inferredcites →https://doi.org/10.1038/nature18642openalex-snapshot
The genetic architecture of type 2 diabetes
inferredcites →https://doi.org/10.1038/ng.1019openalex-snapshot
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
inferredcites →https://doi.org/10.1038/ng.2383openalex-snapshot
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
inferredcites →https://doi.org/10.1038/ng.2653openalex-snapshot
The Genotype-Tissue Expression (GTEx) project
inferredcites →https://doi.org/10.1038/ng.2897openalex-snapshot
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
inferredcites →https://doi.org/10.1038/ng.3367openalex-snapshot
A gene-based association method for mapping traits using reference transcriptome data
inferredcites →https://doi.org/10.1038/ng.3506openalex-snapshot
Integrative approaches for large-scale transcriptome-wide association studies
inferredcites →https://doi.org/10.1038/ng.3538openalex-snapshot
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot
Common SNPs explain a large proportion of the heritability for human height
inferredcites →https://doi.org/10.1038/ng.609openalex-snapshot
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
inferredcites →https://doi.org/10.1038/ng.921openalex-snapshot
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
inferredcites →https://doi.org/10.1038/ng2088openalex-snapshot
A new multipoint method for genome-wide association studies by imputation of genotypes
inferredcites →https://doi.org/10.1038/nmeth.1785openalex-snapshot
A linear complexity phasing method for thousands of genomes
inferredcites →https://doi.org/10.1038/nprot.2011.457openalex-snapshot
Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
inferredcites →https://doi.org/10.1038/nrendo.2016.50openalex-snapshot
Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes
inferredcites →https://doi.org/10.1038/nrg3891openalex-snapshot
The role of regulatory variation in complex traits and disease
inferredcites →https://doi.org/10.1056/nejmoa032922openalex-snapshot
Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes
inferredcites →https://doi.org/10.1073/pnas.0903103106openalex-snapshot
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
inferredcites →https://doi.org/10.1093/bioinformatics/btq340openalex-snapshot
METAL: fast and efficient meta-analysis of genomewide association scans
inferredcites →https://doi.org/10.1093/bioinformatics/btu416openalex-snapshot
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
inferredcites →https://doi.org/10.1101/gr.135350.111openalex-snapshot
GENCODE: The reference human genome annotation for The ENCODE Project
inferredcites →https://doi.org/10.1101/gr.155192.113openalex-snapshot
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
inferredcites →https://doi.org/10.1111/j.1749-6632.2010.05838.xopenalex-snapshot
The genetics of type 2 diabetes: what have we learned from GWAS?
inferredcites →https://doi.org/10.1111/j.2517-6161.1996.tb02080.xopenalex-snapshot
Regression Shrinkage and Selection Via the Lasso
inferredcites →https://doi.org/10.1126/science.1222794openalex-snapshot
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
inferredcites →https://doi.org/10.1126/science.1262110openalex-snapshot
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
inferredcites →https://doi.org/10.1186/gb-2010-11-2-r14openalex-snapshot
Gene ontology analysis for RNA-seq: accounting for selection bias
inferredcites →https://doi.org/10.1371/journal.pgen.1000529openalex-snapshot
A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
inferredcites →https://doi.org/10.1371/journal.pgen.1000888openalex-snapshot
Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
inferredcites →https://doi.org/10.1375/twin.13.6.517openalex-snapshot
A Commentary on ‘Common SNPs Explain a Large Proportion of the Heritability for Human Height’ by Yang et al. (2010)
inferredcites →https://doi.org/10.2337/db07-0337openalex-snapshot
Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance
inferredcites →https://doi.org/10.2337/db09-9028openalex-snapshot
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.2337/db15-1489openalex-snapshot
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion
inferredcites →https://doi.org/10.2337/diabetes.54.12.3402openalex-snapshot
The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/gepi.22290openalex-snapshot
Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome‐wide association studies
inferred← citeshttps://doi.org/10.1007/s00439-023-02568-8openalex-snapshot
Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci
inferred← citeshttps://doi.org/10.1016/bs.adgen.2018.12.001openalex-snapshot
Association mapping in plants in the post-GWAS genomics era
inferred← citeshttps://doi.org/10.1038/s41431-018-0176-5openalex-snapshot
Comparison of methods for transcriptome imputation through application to two common complex diseases
inferred← citeshttps://doi.org/10.1038/s41588-019-0345-7openalex-snapshot
A statistical framework for cross-tissue transcriptome-wide association analysis
inferred← citeshttps://doi.org/10.1093/hmg/ddab056openalex-snapshot
Aggregating multiple expression prediction models improves the power of transcriptome-wide association studies
inferred← citeshttps://doi.org/10.1101/045260openalex-snapshot
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
inferred← citeshttps://doi.org/10.1101/371450openalex-snapshot
Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries
inferred← citeshttps://doi.org/10.1186/s13073-019-0613-2openalex-snapshot
Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
inferred← citeshttps://doi.org/10.1534/genetics.117.300270openalex-snapshot
A Powerful Framework for Integrating eQTL and GWAS Summary Data
inferred← citeshttps://doi.org/10.3389/fgene.2022.1008511openalex-snapshot
Genome-wide imputed differential expression enrichment analysis identifies trait-relevant tissues
inferred← citeshttps://doi.org/10.34944/dspace/4648openalex-snapshot
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
inferred← citeshttps://doi.org/10.5204/thesis.eprints.236251openalex-snapshot
Identifying and understanding the molecular mechanisms of migraine via functional interpretation of genome-wide association study (GWAS) data
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