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Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/9783527628766openalex-snapshot
Molecular Descriptors for Chemoinformatics
inferredcites →https://doi.org/10.1002/ajpa.20518openalex-snapshot
The molecular signature of selection underlying human adaptations
inferredcites →https://doi.org/10.1002/cpt.454openalex-snapshot
Drug Transporters: Advances and Opportunities
inferredcites →https://doi.org/10.1002/jps.23492openalex-snapshot
Oxymorphone Active Uptake at the Blood–Brain Barrier and Population Modeling of its Pharmacokinetic–Pharmacodynamic Relationship
inferredcites →https://doi.org/10.1002/jps.23595openalex-snapshot
Involvement of Carnitine/Organic Cation Transporter OCTN1/SLC22A4 in Gastrointestinal Absorption of Metformin
inferredcites →https://doi.org/10.1002/jps.24453openalex-snapshot
Carrier-Mediated Transport of Nicotine Across the Inner Blood–Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H+ Gradient
inferredcites →https://doi.org/10.1002/jps.24627openalex-snapshot
Transport Mechanism of Nicotine in Primary Cultured Alveolar Epithelial Cells
inferredcites →https://doi.org/10.1002/minf.201000050openalex-snapshot
Combination Rules for Group Fusion in Similarity‐Based Virtual Screening
inferredcites →https://doi.org/10.1002/minf.201300021openalex-snapshot
Pharmacophore Alignment Search Tool (PhAST): Significance Assessment of Chemical Similarity
inferredcites →https://doi.org/10.1002/minf.201400024openalex-snapshot
The Calculation of Molecular Structural Similarity: Principles and Practice
inferredcites →https://doi.org/10.1002/minf.201500004openalex-snapshot
Chemoinformatics at the University of Sheffield 2002–2014
inferredcites →https://doi.org/10.1002/mnfr.200700505openalex-snapshot
Uptake of grape anthocyanins into the rat kidney and the involvement of bilitranslocase
inferredcites →https://doi.org/10.1002/mnfr.201200370openalex-snapshot
Flavone potently stimulates an apical transporter for flavonoids in human intestinal C aco‐2 cells
inferredcites →https://doi.org/10.1006/bbrc.1997.6109openalex-snapshot
Antioxidant Action of Ergothioneine: Assessment of Its Ability to Scavenge Peroxynitrite
inferredcites →https://doi.org/10.1007/164_2015_19openalex-snapshot
Sources for Leads: Natural Products and Libraries
inferredcites →https://doi.org/10.1007/978-1-4419-1132-2_2openalex-snapshot
Natural Products in Drug Discovery: Present Status and Perspectives
inferredcites →https://doi.org/10.1007/978-1-4614-8229-1openalex-snapshot
Transporters in Drug Development
inferredcites →https://doi.org/10.1007/978-1-60761-839-3_6openalex-snapshot
Predicting the Performance of Fingerprint Similarity Searching
inferredcites →https://doi.org/10.1007/978-3-540-78246-9openalex-snapshot
Data Analysis, Machine Learning and Applications
inferredcites →https://doi.org/10.1007/978-3-540-78246-9_38openalex-snapshot
KNIME: The Konstanz Information Miner
inferredcites →https://doi.org/10.1007/978-3-7643-8117-2_4openalex-snapshot
Biodiversity, chemical diversity and drug discovery
inferredcites →https://doi.org/10.1007/978-3-7643-8595-8_4openalex-snapshot
Cheminformatics analysis of natural products: Lessons from nature inspiring the design of new drugs
inferredcites →https://doi.org/10.1007/s00210-007-0219-xopenalex-snapshot
Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1)
inferredcites →https://doi.org/10.1007/s00424-003-1068-1openalex-snapshot
SLC19: the folate/thiamine transporter family
inferredcites →https://doi.org/10.1007/s00425-008-0730-4openalex-snapshot
Evidence for a putative flavonoid translocator similar to mammalian bilitranslocase in grape berries (Vitis vinifera L.) during ripening
inferredcites →https://doi.org/10.1007/s10142-011-0255-yopenalex-snapshot
Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals
inferredcites →https://doi.org/10.1007/s10710-015-9247-3openalex-snapshot
Software review: the KNIME workflow environment and its applications in genetic programming and machine learning
inferredcites →https://doi.org/10.1007/s10822-006-9085-8openalex-snapshot
Feature-map vectors: a new class of informative descriptors for computational drug discovery
inferredcites →https://doi.org/10.1007/s10822-007-9105-3openalex-snapshot
Lead-like, drug-like or “Pub-like”: how different are they?
inferredcites →https://doi.org/10.1007/s10822-011-9437-xopenalex-snapshot
Visualisation of the chemical space of fragments, lead-like and drug-like molecules in PubChem
inferredcites →https://doi.org/10.1007/s11030-006-9054-0openalex-snapshot
Comparing the chemical spaces of metabolites and available chemicals: models of metabolite-likeness
inferredcites →https://doi.org/10.1007/s11095-015-1711-5openalex-snapshot
Transporter-Mediated Disposition of Opioids: Implications for Clinical Drug Interactions
inferredcites →https://doi.org/10.1007/s11306-014-0733-zopenalex-snapshot
A ‘rule of 0.5’ for the metabolite-likeness of approved pharmaceutical drugs
inferredcites →https://doi.org/10.1007/s11655-015-2155-9openalex-snapshot
The application status of Chinese herbal medicine in military health service in China
inferredcites →https://doi.org/10.1007/s12038-012-9195-5openalex-snapshot
Pyrroloquinoline-quinone and its versatile roles in biological processes
inferredcites →https://doi.org/10.1007/s40262-015-0328-5openalex-snapshot
Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics
inferredcites →https://doi.org/10.1016/0003-9861(91)90158-fopenalex-snapshot
The antioxidant action of ergothioneine
inferredcites →https://doi.org/10.1016/0378-8741(84)90092-8openalex-snapshot
Pharmacognosy: The oldest modern science
inferredcites →https://doi.org/10.1016/b978-0-12-398456-2.00037-2openalex-snapshot
Bioavailability of Flavonoids
inferredcites →https://doi.org/10.1016/b978-0-12-407695-2.00009-3openalex-snapshot
New Insights into the Transport Mechanisms in Plant Vacuoles
inferredcites →https://doi.org/10.1016/b978-0-12-800223-0.00004-9openalex-snapshot
Biology of the Major Facilitative Folate Transporters SLC19A1 and SLC46A1
inferredcites →https://doi.org/10.1016/b978-0-12-800874-4.00021-0openalex-snapshot
Discovery and Development of Lead Compounds from Natural Sources Using Computational Approaches
inferredcites →https://doi.org/10.1016/b978-0-12-813006-3.00022-2openalex-snapshot
Bioavailability of Flavonoids: The Role of Cell Membrane Transporters
inferredcites →https://doi.org/10.1016/c2011-1-09286-xopenalex-snapshot
Polyphenols in Human Health and Disease
inferredcites →https://doi.org/10.1016/c2013-0-18594-7openalex-snapshot
Evidence-Based Validation of Herbal Medicine
inferredcites →https://doi.org/10.1016/j.addr.2016.01.018openalex-snapshot
Molecular inflation, attrition and the rule of five
inferredcites →https://doi.org/10.1016/j.bbadis.2011.09.017openalex-snapshot
Ergothioneine; antioxidant potential, physiological function and role in disease
inferredcites →https://doi.org/10.1016/j.bbagen.2008.01.008openalex-snapshot
Redox control in actinobacteria
inferredcites →https://doi.org/10.1016/j.bbamem.2005.06.006openalex-snapshot
Structure–affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites
inferredcites →https://doi.org/10.1016/j.bbrc.2007.08.041openalex-snapshot
Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes
inferredcites →https://doi.org/10.1016/j.bbrc.2015.12.124openalex-snapshot
Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis
inferredcites →https://doi.org/10.1016/j.bcp.2005.06.024openalex-snapshot
Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1
inferredcites →https://doi.org/10.1016/j.bcp.2006.09.024openalex-snapshot
Properties of flavonoids influencing the binding to bilitranslocase investigated by neural network modelling
inferredcites →https://doi.org/10.1016/j.bcp.2013.06.019openalex-snapshot
Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration
inferredcites →https://doi.org/10.1016/j.bmc.2011.11.064openalex-snapshot
Softening the Rule of Five—where to draw the line?
inferredcites →https://doi.org/10.1016/j.cbi.2015.08.027openalex-snapshot
Pyrroloquinoline quinone (PQQ) has potential to ameliorate streptozotocin-induced diabetes mellitus and oxidative stress in mice: A histopathological and biochemical study
inferredcites →https://doi.org/10.1016/j.cell.2015.07.022openalex-snapshot
A Call for Systematic Research on Solute Carriers
inferredcites →https://doi.org/10.1016/j.chembiol.2014.08.013openalex-snapshot
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
inferredcites →https://doi.org/10.1016/j.chembiol.2015.11.015openalex-snapshot
Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter
inferredcites →https://doi.org/10.1016/j.dmpk.2015.02.003openalex-snapshot
Organic cation transporter Octn1-mediated uptake of food-derived antioxidant ergothioneine into infiltrating macrophages during intestinal inflammation in mice
inferredcites →https://doi.org/10.1016/j.dmpk.2015.11.006openalex-snapshot
Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells
inferredcites →https://doi.org/10.1016/j.drudis.2007.10.022openalex-snapshot
A Sorcerer's apprentice and The Rule of Five: from rule-of-thumb to commandment and beyond
inferredcites →https://doi.org/10.1016/j.drudis.2008.10.011openalex-snapshot
‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries
inferredcites →https://doi.org/10.1016/j.drudis.2011.05.010openalex-snapshot
Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
inferredcites →https://doi.org/10.1016/j.drudis.2012.11.008openalex-snapshot
The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
inferredcites →https://doi.org/10.1016/j.drudis.2013.07.014openalex-snapshot
Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery
inferredcites →https://doi.org/10.1016/j.drudis.2014.02.003openalex-snapshot
Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?
inferredcites →https://doi.org/10.1016/j.exger.2016.04.008openalex-snapshot
Pyrroloquinoline quinone enhances the resistance to oxidative stress and extends lifespan upon DAF-16 and SKN-1 activities in C. elegans
inferredcites →https://doi.org/10.1016/j.febslet.2005.12.009openalex-snapshot
ABC transporters involved in the transport of plant secondary metabolites
inferredcites →https://doi.org/10.1016/j.febslet.2006.01.002openalex-snapshot
Genomics of plant ABC transporters: The alphabet of photosynthetic life forms or just holes in membranes?
inferredcites →https://doi.org/10.1016/j.foodres.2005.02.015openalex-snapshot
Hepatic uptake of grape anthocyanins and the role of bilitranslocase
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2003.11.005openalex-snapshot
Ergothioneine rescues PC12 cells from β-amyloid-induced apoptotic death
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.04.013openalex-snapshot
Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6
inferredcites →https://doi.org/10.1016/j.gene.2014.10.001openalex-snapshot
Identification and characterization of 5′-flanking region of the human riboflavin transporter 1 gene (SLC52A1)
inferredcites →https://doi.org/10.1016/j.ijmm.2006.01.039openalex-snapshot
The truth about antibiotics
inferredcites →https://doi.org/10.1016/j.jep.2016.06.052openalex-snapshot
Botanical drugs in Ayurveda and Traditional Chinese Medicine
inferredcites →https://doi.org/10.1016/j.jep.2016.07.030openalex-snapshot
The Ayurvedic Pharmacopoeia of India, development and perspectives
inferredcites →https://doi.org/10.1016/j.jnutbio.2013.07.008openalex-snapshot
Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects
inferredcites →https://doi.org/10.1016/j.mam.2005.07.008openalex-snapshot
Medicinal plants: Traditions of yesterday and drugs of tomorrow
inferredcites →https://doi.org/10.1016/j.mam.2012.07.006openalex-snapshot
Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors
inferredcites →https://doi.org/10.1016/j.mam.2012.07.014openalex-snapshot
Novel riboflavin transporter family RFVT/SLC52: Identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52
inferredcites →https://doi.org/10.1016/j.mam.2012.12.009openalex-snapshot
The ABCs of membrane transporters in health and disease (SLC series): Introduction
inferredcites →https://doi.org/10.1016/j.neuropharm.2016.04.025openalex-snapshot
Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease
inferredcites →https://doi.org/10.1016/j.nucmedbio.2012.11.014openalex-snapshot
Radiotracers for cardiac sympathetic innervation: Transport kinetics and binding affinities for the human norepinephrine transporter
inferredcites →https://doi.org/10.1016/j.pisc.2015.06.004openalex-snapshot
The transporter-mediated cellular uptake of pharmaceutical drugs is based on their metabolite-likeness and not on their bulk biophysical properties: Towards a systems pharmacology
inferredcites →https://doi.org/10.1016/j.tips.2014.10.005openalex-snapshot
What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?
inferredcites →https://doi.org/10.1016/j.tips.2015.07.006openalex-snapshot
Fitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can Fly
inferredcites →https://doi.org/10.1016/j.toxlet.2015.08.011openalex-snapshot
Pyrroloquinoline quinone-conferred neuroprotection in rotenone models of Parkinson’s disease
inferredcites →https://doi.org/10.1016/j.ypmed.2011.12.001openalex-snapshot
The ergothioneine transporter controls and indicates ergothioneine activity — A review
inferredcites →https://doi.org/10.1016/j.ypmed.2011.12.006openalex-snapshot
Effect of ergothioneine on acute lung injury and inflammation in cytokine insufflated rats
inferredcites →https://doi.org/10.1016/j.ypmed.2011.12.028openalex-snapshot
The bioavailability of ergothioneine from mushrooms (Agaricus bisporus) and the acute effects on antioxidant capacity and biomarkers of inflammation
inferredcites →https://doi.org/10.1016/s0006-291x(02)00927-0openalex-snapshot
The interaction of anthocyanins with bilitranslocase
inferredcites →https://doi.org/10.1016/s0014-2999(03)01381-5openalex-snapshot
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics
inferredcites →https://doi.org/10.1016/s0022-3565(24)34949-3openalex-snapshot
The Interaction and Transport of β-Lactam Antibiotics with the Cloned Rat Renal Organic Anion Transporter 1
inferredcites →https://doi.org/10.1016/s0065-2164(08)70514-8openalex-snapshot
Intermediary Metabolism and Antibiotic Synthesis
inferredcites →https://doi.org/10.1016/s0169-409x(96)00423-1openalex-snapshot
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
inferredcites →https://doi.org/10.1016/s0169-5347(00)89013-8openalex-snapshot
Pheromones, social behaviour and the functions of secondary metabolism in bacteria
inferredcites →https://doi.org/10.1016/s0278-6915(99)00098-8openalex-snapshot
Protection Against Oxidative Damage and Cell Death by the Natural Antioxidant Ergothioneine
inferredcites →https://doi.org/10.1016/s1359-6446(05)03700-1openalex-snapshot
Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits
inferredcites →https://doi.org/10.1017/cbo9780511623486openalex-snapshot
The Neutral Theory of Molecular Evolution
inferredcites →https://doi.org/10.1017/s0007114508066762openalex-snapshot
Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1)
inferredcites →https://doi.org/10.1021/acs.jcim.5b00559openalex-snapshot
ZINC 15 – Ligand Discovery for Everyone
inferredcites →https://doi.org/10.1021/acs.jnatprod.5b01055openalex-snapshot
Natural Products as Sources of New Drugs from 1981 to 2014
inferredcites →https://doi.org/10.1021/bi00670a032openalex-snapshot
Evolution of enzyme function and the development of catalytic efficiency
inferredcites →https://doi.org/10.1021/ci010366aopenalex-snapshot
Is There a Difference between Leads and Drugs? A Historical Perspective
inferredcites →https://doi.org/10.1021/ci025596jopenalex-snapshot
Combination of Fingerprint-Based Similarity Coefficients Using Data Fusion
inferredcites →https://doi.org/10.1021/ci049615wopenalex-snapshot
Analysis of Data Fusion Methods in Virtual Screening: Theoretical Model
inferredcites →https://doi.org/10.1021/ci0601517openalex-snapshot
Comparative QSAR- and Fragments Distribution Analysis of Drugs, Druglikes, Metabolic Substances, and Antimicrobial Compounds
inferredcites →https://doi.org/10.1021/ci100010vopenalex-snapshot
When is Chemical Similarity Significant? The Statistical Distribution of Chemical Similarity Scores and Its Extreme Values
inferredcites →https://doi.org/10.1021/ci100091eopenalex-snapshot
Rationalizing Three-Dimensional Activity Landscapes and the Influence of Molecular Representations on Landscape Topology and the Formation of Activity Cliffs
inferredcites →https://doi.org/10.1021/ci2001023openalex-snapshot
Build-Up Algorithm for Atomic Correspondence between Chemical Structures
inferredcites →https://doi.org/10.1021/ci2003472openalex-snapshot
Introduction of the Conditional Correlated Bernoulli Model of Similarity Value Distributions and its Application to the Prospective Prediction of Fingerprint Search Performance
inferredcites →https://doi.org/10.1021/ci3001277openalex-snapshot
ZINC: A Free Tool to Discover Chemistry for Biology
inferredcites →https://doi.org/10.1021/ci300512qopenalex-snapshot
BioSM: Metabolomics Tool for Identifying Endogenous Mammalian Biochemical Structures in Chemical Structure Space
inferredcites →https://doi.org/10.1021/ci300547gopenalex-snapshot
Combination of Similarity Rankings Using Data Fusion
inferredcites →https://doi.org/10.1021/ci3005513openalex-snapshot
Chemogenomics Approaches to Rationalizing the Mode-of-Action of Traditional Chinese and Ayurvedic Medicines
inferredcites →https://doi.org/10.1021/ci5005702openalex-snapshot
Maximum Common Substructure-Based Data Fusion in Similarity Searching
inferredcites →https://doi.org/10.1021/ci700286xopenalex-snapshot
Natural Product-likeness Score and Its Application for Prioritization of Compound Libraries
inferredcites →https://doi.org/10.1021/jm020155copenalex-snapshot
Do Structurally Similar Molecules Have Similar Biological Activity?
inferredcites →https://doi.org/10.1021/jm100933wopenalex-snapshot
Activity Landscape Representations for Structure−Activity Relationship Analysis
inferredcites →https://doi.org/10.1021/np200906sopenalex-snapshot
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
inferredcites →https://doi.org/10.1023/a:1008752200506openalex-snapshot
Combination of molecular similarity measures using data fusion
inferredcites →https://doi.org/10.1023/a:1027221424359openalex-snapshot
Similarity and Dissimilarity: A Medicinal Chemist's View
inferredcites →https://doi.org/10.1038/19986openalex-snapshot
A family of mammalian Na+-dependent L-ascorbic acid transporters
inferredcites →https://doi.org/10.1038/280843a0openalex-snapshot
A novel coenzyme from bacterial primary alcohol dehydrogenases
inferredcites →https://doi.org/10.1038/cdd.2009.163openalex-snapshot
The unusual amino acid L-ergothioneine is a physiologic cytoprotectant
inferredcites →https://doi.org/10.1038/nature01568openalex-snapshot
The evolutionary origin of complex features
inferredcites →https://doi.org/10.1038/nature18959openalex-snapshot
Tempo and mode of genome evolution in a 50,000-generation experiment
inferredcites →https://doi.org/10.1038/nbt.2488openalex-snapshot
A community-driven global reconstruction of human metabolism
inferredcites →https://doi.org/10.1038/nchembio.1590openalex-snapshot
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity
inferredcites →https://doi.org/10.1038/nchembio0707-360openalex-snapshot
Revisiting the ancient concept of botanical therapeutics
inferredcites →https://doi.org/10.1038/nrd.2015.44openalex-snapshot
Implications of endogenous roles of transporters for drug discovery: hitchhiking and metabolite-likeness
inferredcites →https://doi.org/10.1038/nrd2438openalex-snapshot
Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
inferredcites →https://doi.org/10.1038/nrd3028openalex-snapshot
Membrane transporters in drug development
inferredcites →https://doi.org/10.1038/nrd4510openalex-snapshot
The re-emergence of natural products for drug discovery in the genomics era
inferredcites →https://doi.org/10.1038/srep35306openalex-snapshot
Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus
inferredcites →https://doi.org/10.1039/9781782622246-00348openalex-snapshot
Chapter 13. Natural Product Scaffolds of Value in Medicinal Chemistry
inferredcites →https://doi.org/10.1039/b208815kopenalex-snapshot
Natural products ? a simple model to explain chemical diversity
inferredcites →https://doi.org/10.1039/b513504bopenalex-snapshot
Natural products: sources and databases
inferredcites →https://doi.org/10.1039/c4cs00351aopenalex-snapshot
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
inferredcites →https://doi.org/10.1039/c6np00006aopenalex-snapshot
Structural and mechanistic diversity of multidrug transporters
inferredcites →https://doi.org/10.1073/pnas.0304987101openalex-snapshot
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney
inferredcites →https://doi.org/10.1073/pnas.0408624102openalex-snapshot
Discovery of the ergothioneine transporter
inferredcites →https://doi.org/10.1073/pnas.0914631107openalex-snapshot
Gene-culture coevolution in the age of genomics
inferredcites →https://doi.org/10.1073/pnas.1110633108openalex-snapshot
Estimating the timing of early eukaryotic diversification with multigene molecular clocks
inferredcites →https://doi.org/10.1073/pnas.1314939111openalex-snapshot
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
inferredcites →https://doi.org/10.1074/jbc.m116.745216openalex-snapshot
An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network
inferredcites →https://doi.org/10.1080/09168451.2015.1062715openalex-snapshot
Recent progress in studies on the health benefits of pyrroloquinoline quinone
inferredcites →https://doi.org/10.1080/09168451.2015.1083396openalex-snapshot
A mushroom-derived amino acid, ergothioneine, is a potential inhibitor of inflammation-related DNA halogenation
inferredcites →https://doi.org/10.1086/421051openalex-snapshot
Genetic Signatures of Strong Recent Positive Selection at the Lactase Gene
inferredcites →https://doi.org/10.1089/15230860152664966openalex-snapshot
Pyrroloquinoline Quinone (PQQ) and Quinoprotein Enzymes
inferredcites →https://doi.org/10.1089/ars.2016.6778openalex-snapshot
Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation
inferredcites →https://doi.org/10.1093/brain/awv342openalex-snapshot
Free-thiamine is a potential biomarker of thiamine transporter-2 deficiency: a treatable cause of Leigh syndrome
inferredcites →https://doi.org/10.1093/cvr/cvp290openalex-snapshot
Expression of bilitranslocase in the vascular endothelium and its function as a flavonoid transporter
inferredcites →https://doi.org/10.1093/ijnp/pyu001openalex-snapshot
Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability
inferredcites →https://doi.org/10.1093/jb/mvr095openalex-snapshot
Riboflavin transporter is finally identified
inferredcites →https://doi.org/10.1093/jn/130.4.719openalex-snapshot
Physiological Importance of Quinoenzymes and the O-Quinone Family of Cofactors
inferredcites →https://doi.org/10.1093/nar/gkn899openalex-snapshot
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape
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The Transporter Classification Database (TCDB): recent advances
inferredcites →https://doi.org/10.1093/pan/mpl013openalex-snapshot
Matching as Nonparametric Preprocessing for Reducing Model Dependence in Parametric Causal Inference
inferredcites →https://doi.org/10.1096/fj.201600906ropenalex-snapshot
Early PQQ supplementation has persistent long‐term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice
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Revealing the paradox of drug reward in human evolution
inferredcites →https://doi.org/10.1098/rstb.2006.1843openalex-snapshot
Eukaryotic organisms in Proterozoic oceans
inferredcites →https://doi.org/10.1098/rstb.2010.0268openalex-snapshot
Evolution of lactase persistence: an example of human niche construction
inferredcites →https://doi.org/10.1101/cshperspect.a016121openalex-snapshot
Paleobiological Perspectives on Early Eukaryotic Evolution
inferredcites →https://doi.org/10.1111/cbdd.12011openalex-snapshot
Molecular Scaffold Analysis of Natural Products Databases in the Public Domain
inferredcites →https://doi.org/10.1111/febs.12268openalex-snapshot
Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it
inferredcites →https://doi.org/10.1111/j.1476-5381.2011.01350.xopenalex-snapshot
The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C
inferredcites →https://doi.org/10.1111/j.1476-5381.2012.01975.xopenalex-snapshot
The solute carrier 6 family of transporters
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Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu-tang across human intestinal Caco-2 cell monolayers1
inferredcites →https://doi.org/10.1111/jnc.13092openalex-snapshot
Major involvement of Na + ‐dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells
inferredcites →https://doi.org/10.1111/jphp.12006openalex-snapshot
Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1)
inferredcites →https://doi.org/10.1113/jphysiol.2006.107904openalex-snapshot
Molecular interactions between dipeptides, drugs and the human intestinal H+–oligopeptide cotransporter hPEPT1
inferredcites →https://doi.org/10.1124/dmd.104.003301openalex-snapshot
POSSIBLE INVOLVEMENT OF ORGANIC ANION TRANSPORTER 2 ON THE INTERACTION OF THEOPHYLLINE WITH ERYTHROMYCIN IN THE HUMAN LIVER
inferredcites →https://doi.org/10.1124/dmd.105.006791openalex-snapshot
INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
inferredcites →https://doi.org/10.1124/dmd.113.055723openalex-snapshot
The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
inferredcites →https://doi.org/10.1124/dmd.114.061002openalex-snapshot
Involvement of the H+/Organic Cation Antiporter in Nicotine Transport in Rat Liver
inferredcites →https://doi.org/10.1124/jpet.102.034629openalex-snapshot
Transport Mechanisms of Nicotine across the Human Intestinal Epithelial Cell Line Caco-2
inferredcites →https://doi.org/10.1126/science.1155725openalex-snapshot
Evolution of Mammals and Their Gut Microbes
inferredcites →https://doi.org/10.1126/science.1168243openalex-snapshot
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
inferredcites →https://doi.org/10.1126/science.1198719openalex-snapshot
Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans
inferredcites →https://doi.org/10.1126/science.2549636openalex-snapshot
Nutritional Importance of Pyrroloquinoline Quinone
inferredcites →https://doi.org/10.1126/science.aag0776openalex-snapshot
Detection of human adaptation during the past 2000 years
inferredcites →https://doi.org/10.1126/science.aag2737openalex-snapshot
Eocene lantern fruits from Gondwanan Patagonia and the early origins of Solanaceae
inferredcites →https://doi.org/10.1146/annurev-micro-090110-102830openalex-snapshot
The Human Gut Microbiome: Ecology and Recent Evolutionary Changes
inferredcites →https://doi.org/10.1146/annurev.anthro.28.1.27openalex-snapshot
The Chemical Ecology of Human Ingestive Behaviors
inferredcites →https://doi.org/10.1152/ajpcell.00342.2014openalex-snapshot
Identification and characterization of the minimal 5′-regulatory region of the human riboflavin transporter-3 (SLC52A3) in intestinal epithelial cells
inferredcites →https://doi.org/10.1152/ajprenal.00319.2007openalex-snapshot
Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G
inferredcites →https://doi.org/10.1177/0165551512470042openalex-snapshot
Comparison of chemical similarity measures using different numbers of query structures
inferredcites →https://doi.org/10.1177/153537020322800205openalex-snapshot
Pyrroloquinoline Quinone Improves Growth and Reproductive Performance in Mice Fed Chemically Defined Diets
inferredcites →https://doi.org/10.1186/1471-2105-10-s15-s10openalex-snapshot
Physicochemical property space distribution among human metabolites, drugs and toxins
inferredcites →https://doi.org/10.1186/1758-2946-5-26openalex-snapshot
Open-source platform to benchmark fingerprints for ligand-based virtual screening
inferredcites →https://doi.org/10.1186/s13321-016-0148-0openalex-snapshot
Comparing structural fingerprints using a literature-based similarity benchmark
inferredcites →https://doi.org/10.1186/s13321-017-0198-yopenalex-snapshot
Analysis of drug–endogenous human metabolite similarities in terms of their maximum common substructures
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What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1021/acssuschemeng.7b03394openalex-snapshot
Channel Interactions and Robust Inference for Ratiometric β-Lactamase Assay Data: A Tox21 Library Analysis
inferred← citeshttps://doi.org/10.1039/d4np00066hopenalex-snapshot
Privileged natural product compound classes for anti-inflammatory drug development
inferred← citeshttps://doi.org/10.1101/155697openalex-snapshot
Novel 'Housekeeping' Genes and an Unusually Heterogeneous Distribution of Transporter Expression Profiles in Human Tissues and Cell Lines, Assessed Using the Gini Coefficient
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