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Transcriptomic profiling of nematode parasites surviving after vaccine exposure

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.299.16.1937openalex-snapshot
Efficacy of Current Drugs Against Soil-Transmitted Helminth Infections
inferredcites →https://doi.org/10.1016/0034-5288(93)90025-bopenalex-snapshot
Evaluation of aspects of the protection afforded to sheep immunised with a gut membrane protein of Haemonchus contortus
inferredcites →https://doi.org/10.1016/bs.apar.2016.02.009openalex-snapshot
Genetic Diversity and Population Structure of Haemonchus contortus
inferredcites →https://doi.org/10.1016/j.biotechadv.2015.10.003openalex-snapshot
The complement of family M1 aminopeptidases of Haemonchus contortus — Biotechnological implications
inferredcites →https://doi.org/10.1016/j.coi.2015.04.002openalex-snapshot
Host–pathogen interaction during bacterial vaccination
inferredcites →https://doi.org/10.1016/j.ijpara.2003.10.002openalex-snapshot
Genetic analysis of inbreeding of two strains of the parasitic nematode Haemonchus contortus
inferredcites →https://doi.org/10.1016/j.molbiopara.2015.08.001openalex-snapshot
Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus
inferredcites →https://doi.org/10.1016/j.molbiopara.2016.11.005openalex-snapshot
WormBase ParaSite − a comprehensive resource for helminth genomics
inferredcites →https://doi.org/10.1016/j.molimm.2015.06.008openalex-snapshot
Diverse cellular and organismal functions of the lysosomal thiol reductase GILT
inferredcites →https://doi.org/10.1016/j.pt.2004.08.002openalex-snapshot
Veterinary anthelmintics: old and new
inferredcites →https://doi.org/10.1016/j.pt.2004.08.003openalex-snapshot
The changing landscape of antiparasitic drug discovery for veterinary medicine
inferredcites →https://doi.org/10.1016/j.pt.2015.09.005openalex-snapshot
The Burden of Livestock Parasites on the Poor
inferredcites →https://doi.org/10.1016/j.vaccine.2010.12.004openalex-snapshot
The potential economic value of a hookworm vaccine
inferredcites →https://doi.org/10.1016/j.vaccine.2016.03.112openalex-snapshot
Human anthelminthic vaccines: Rationale and challenges
inferredcites →https://doi.org/10.1016/j.vetpar.2008.01.032openalex-snapshot
Vaccination against Haemonchus contortus: Performance of native parasite gut membrane glycoproteins in Merino lambs grazing contaminated pasture
inferredcites →https://doi.org/10.1016/j.vetpar.2011.11.048openalex-snapshot
An inconvenient truth: Global worming and anthelmintic resistance
inferredcites →https://doi.org/10.1016/j.vetpar.2016.02.028openalex-snapshot
The ‘Toolbox’ of strategies for managing Haemonchus contortus in goats: What’s in and what’s out
inferredcites →https://doi.org/10.1016/s0020-7519(03)00167-xopenalex-snapshot
The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids
inferredcites →https://doi.org/10.1016/s0140-6736(10)62225-8openalex-snapshot
Serotype replacement in disease after pneumococcal vaccination
inferredcites →https://doi.org/10.1016/s0140-6736(16)32123-7openalex-snapshot
Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/s0166-6851(99)00121-8openalex-snapshot
Identification of promoter elements of parasite nematode genes in transgenic Caenorhabditis elegans
inferredcites →https://doi.org/10.1016/s0169-4758(99)01399-xopenalex-snapshot
The Development of Vaccines against Gastrointestinal Nematode Parasites, Particularly Haemonchus contortus
inferredcites →https://doi.org/10.1016/s1471-4922(03)00189-2openalex-snapshot
Digestive proteases of blood-feeding nematodes
inferredcites →https://doi.org/10.1017/s0022149x15000279openalex-snapshot
Vaccination of sheep and cattle against haemonchosis
inferredcites →https://doi.org/10.1017/s0031182099005727openalex-snapshot
Vaccine development and diagnostics of Dictyocaulus viviparus
inferredcites →https://doi.org/10.1038/nature01279openalex-snapshot
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot
Fast gapped-read alignment with Bowtie 2
inferredcites →https://doi.org/10.1046/j.1365-3024.1997.d01-205.xopenalex-snapshot
Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11
inferredcites →https://doi.org/10.1046/j.1365-3024.2000.00277.xopenalex-snapshot
Relative protective properties of three membrane glycoprotein fractions from Haemonchus contortus
inferredcites →https://doi.org/10.1091/mbc.e07-09-0982openalex-snapshot
The Mood Stabilizer Valproate Inhibits both Inositol- and Diacylglycerol-signaling Pathways inCaenorhabditis elegans
inferredcites →https://doi.org/10.1093/bioinformatics/btp120openalex-snapshot
TopHat: discovering splice junctions with RNA-Seq
inferredcites →https://doi.org/10.1093/bioinformatics/btu638openalex-snapshot
HTSeq—a Python framework to work with high-throughput sequencing data
inferredcites →https://doi.org/10.1093/nar/gkh379openalex-snapshot
AUGUSTUS: a web server for gene finding in eukaryotes
inferredcites →https://doi.org/10.1093/nar/gkp971openalex-snapshot
MEROPS: the peptidase database
inferredcites →https://doi.org/10.1093/nar/gkq1268openalex-snapshot
RATT: Rapid Annotation Transfer Tool
inferredcites →https://doi.org/10.1098/rsif.2007.0236openalex-snapshot
Vaccine-induced pathogen strain replacement: what are the mechanisms?
inferredcites →https://doi.org/10.1098/rspb.2016.2562openalex-snapshot
Why does drug resistance readily evolve but vaccine resistance does not?
inferredcites →https://doi.org/10.1111/j.0141-9838.2004.00667.xopenalex-snapshot
Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep
inferredcites →https://doi.org/10.1111/j.1365-3024.2005.00750.xopenalex-snapshot
Protection induced by vaccinating sheep with a thiol‐binding extract ofHaemonchus contortusmembranes is associated with its protease components
inferredcites →https://doi.org/10.1111/j.1365-3024.2010.01242.xopenalex-snapshot
Antibodies from sheep immunized against Haemonchus contortus with H‐gal‐GP inhibit the haemoglobinase activity of this protease complex
inferredcites →https://doi.org/10.1186/1297-9716-44-111openalex-snapshot
Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans
inferredcites →https://doi.org/10.1186/gb-2013-14-8-r88openalex-snapshot
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
inferredcites →https://doi.org/10.1186/gb-2013-14-8-r89openalex-snapshot
The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus
inferredcites →https://doi.org/10.1186/gb-2014-15-2-r29openalex-snapshot
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1242/dev.02767openalex-snapshot
SEL-2, theC. elegansneurobeachin/LRBA homolog, is a negative regulator oflin-12/Notchactivity and affects endosomal traffic in polarized epithelial cells
inferredcites →https://doi.org/10.1371/journal.pntd.0001417openalex-snapshot
Low Efficacy of Single-Dose Albendazole and Mebendazole against Hookworm and Effect on Concomitant Helminth Infection in Lao PDR
inferredcites →https://doi.org/10.1371/journal.pntd.0005385openalex-snapshot
Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine
inferredcites →https://doi.org/10.1371/journal.ppat.0030168openalex-snapshot
Vaccine Escape Recombinants Emerge after Pneumococcal Vaccination in the United States
inferredcites →https://doi.org/10.1586/14760584.2014.893195openalex-snapshot
Vaccination against helminth parasite infections
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/2020.06.19.161729openalex-snapshot
Strongyle-resistant sheep express their potential across environments and leave limited scope for parasite plasticity
inferred← citeshttps://doi.org/10.1101/450692openalex-snapshot
The global diversity of the major parasitic nematode Haemonchus contortus is shaped by human intervention and climate
inferred← citeshttps://doi.org/10.3389/fcimb.2018.00067openalex-snapshot
Metazoan Parasite Vaccines: Present Status and Future Prospects
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