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Comprehensive genome and transcriptome analysis reveals genetic basis for gene fusions in cancer

https://doi.org/10.1101/148684
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1098-2264(200001)27:1<69::aid-gcc9>3.0.co;2-5openalex-snapshot
Identification and characterization ofBCL6 translocation partner genes in primary gastric high-grade B-cell lymphoma: Heat shock protein 89 alpha is a novel fusion partner gene ofBCL6
inferredcites →https://doi.org/10.1007/s11010-010-0494-6openalex-snapshot
Depletion of a single nucleoporin, Nup107, induces apoptosis in eukaryotic cells
inferredcites →https://doi.org/10.1016/j.ccell.2014.09.010openalex-snapshot
The Architecture and Evolution of Cancer Neochromosomes
inferredcites →https://doi.org/10.1016/j.cell.2010.11.055openalex-snapshot
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
inferredcites →https://doi.org/10.1016/j.cell.2012.04.024openalex-snapshot
Mutational Processes Molding the Genomes of 21 Breast Cancers
inferredcites →https://doi.org/10.1016/j.cell.2015.11.054openalex-snapshot
Chromothripsis and Kataegis Induced by Telomere Crisis
inferredcites →https://doi.org/10.1016/j.gore.2015.06.005openalex-snapshot
FGFR3–TACC3: A novel gene fusion in cervical cancer
inferredcites →https://doi.org/10.1016/j.tig.2014.01.001openalex-snapshot
The role of microhomology in genomic structural variation
inferredcites →https://doi.org/10.1016/j.trecan.2016.07.006openalex-snapshot
Intergenically Spliced Chimeric RNAs in Cancer
inferredcites →https://doi.org/10.1038/cr.2013.158openalex-snapshot
Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/ng0298-184openalex-snapshot
A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma
inferredcites →https://doi.org/10.1038/nrg.2015.25openalex-snapshot
Mechanisms underlying structural variant formation in genomic disorders
inferredcites →https://doi.org/10.1038/onc.2014.406openalex-snapshot
The landscape and therapeutic relevance of cancer-associated transcript fusions
inferredcites →https://doi.org/10.1038/oncsis.2014.45openalex-snapshot
Kinome-wide screening of HER2+ breast cancer cells for molecules that mediate cell proliferation or sensitize cells to trastuzumab therapy
inferredcites →https://doi.org/10.1038/sj.leu.2404856openalex-snapshot
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma
inferredcites →https://doi.org/10.1093/nar/gku1003openalex-snapshot
STRING v10: protein–protein interaction networks, integrated over the tree of life
inferredcites →https://doi.org/10.1093/nar/gkw1083openalex-snapshot
OUP accepted manuscript
inferredcites →https://doi.org/10.1097/jto.0b013e3182721ed1openalex-snapshot
Identification of CCDC6-RET Fusion in the Human Lung Adenocarcinoma Cell Line, LC-2/ad
inferredcites →https://doi.org/10.1126/science.1117679openalex-snapshot
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
inferredcites →https://doi.org/10.1126/science.aaa0355openalex-snapshot
The human transcriptome across tissues and individuals
inferredcites →https://doi.org/10.1186/1755-8794-4-11openalex-snapshot
Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples
inferredcites →https://doi.org/10.1371/journal.pgen.1006714openalex-snapshot
Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions
inferredcites →https://doi.org/10.1371/journal.pone.0104567openalex-snapshot
Tandem RNA Chimeras Contribute to Transcriptome Diversity in Human Population and Are Associated with Intronic Genetic Variants

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.omtn.2020.01.023openalex-snapshot
Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts
inferred← citeshttps://doi.org/10.1038/s41467-019-13885-wopenalex-snapshot
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
inferred← citeshttps://doi.org/10.1101/183889openalex-snapshot
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types
inferred← citeshttps://doi.org/10.1101/2025.02.10.637348openalex-snapshot
Systematic silencing of oncogenic fusion transcripts with ultra-precise CRISPR-Cas13b
inferred← citeshttps://doi.org/10.3892/or.2019.7199openalex-snapshot
MPZL1 promotes tumor cell proliferation and migration via activation of Src kinase in ovarian cancer
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