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Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI
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A Regulatory Archipelago Controls Hox Genes Transcription in Digits
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Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome
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Transcript Dynamics of Proinflammatory Genes Revealed by Sequence Analysis of Subcellular RNA Fractions
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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
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Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
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Super-Enhancers in the Control of Cell Identity and Disease
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Enhancer Interaction Networks as a Means for Singular Olfactory Receptor Expression
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The 3D Genome as Moderator of Chromosomal Communication
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Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control
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Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization
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Cohesin Loss Eliminates All Loop Domains
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High-Resolution Profiling of Drosophila Replication Start Sites Reveals a DNA Shape and Chromatin Signature of Metazoan Origins
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A Simple Grammar Defines Activating and Repressing cis-Regulatory Elements in Photoreceptors
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Combinatorial function of transcription factors and cofactors
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Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
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eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
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Modification of Enhancer Chromatin: What, How, and Why?
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Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers
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Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells
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Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche
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Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival
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Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators
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Genome-wide Chromatin Interactions of the Nanog Locus in Pluripotency, Differentiation, and Reprogramming
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PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation
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Decoding enhancers using massively parallel reporter assays
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Hi–C: A comprehensive technique to capture the conformation of genomes
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Hedgehog Controls Limb Development by Regulating the Activities of Distinct Transcriptional Activator and Repressor Forms of Cubitus interruptus
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The ETS-domain transcription factor family
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Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
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Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
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Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
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Histone modifications at human enhancers reflect global cell-type-specific gene expression
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An oestrogen-receptor-α-bound human chromatin interactome
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Spatial partitioning of the regulatory landscape of the X-inactivation centre
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Topological domains in mammalian genomes identified by analysis of chromatin interactions
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An integrated encyclopedia of DNA elements in the human genome
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Topology of mammalian developmental enhancers and their regulatory landscapes
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Enhancer loops appear stable during development and are associated with paused polymerase
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Super-enhancers delineate disease-associated regulatory nodes in T cells
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Two independent modes of chromatin organization revealed by cohesin removal
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GREAT improves functional interpretation of cis-regulatory regions
inferredcites →https://doi.org/10.1038/ng1966openalex-snapshot
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
inferredcites →https://doi.org/10.1038/ni.2432openalex-snapshot
Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot
Fast gapped-read alignment with Bowtie 2
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Iterative correction of Hi-C data reveals hallmarks of chromosome organization
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Orchestrating high-throughput genomic analysis with Bioconductor
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Organization and function of the 3D genome
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Erratum: Organization and function of the 3D genome
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inferredcites →https://doi.org/10.1038/nrg3207openalex-snapshot
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inferredcites →https://doi.org/10.1038/nrg3682openalex-snapshot
Transcriptional enhancers: from properties to genome-wide predictions
inferredcites →https://doi.org/10.1038/nrg3684openalex-snapshot
In pursuit of design principles of regulatory sequences
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Enhancer biology and enhanceropathies
inferredcites →https://doi.org/10.1038/onc.2015.352openalex-snapshot
ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression
inferredcites →https://doi.org/10.1073/pnas.0907623106openalex-snapshot
Conditional c- myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation
inferredcites →https://doi.org/10.1073/pnas.1016071107openalex-snapshot
Histone H3K27ac separates active from poised enhancers and predicts developmental state
inferredcites →https://doi.org/10.1073/pnas.1317023110openalex-snapshot
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
inferredcites →https://doi.org/10.1073/pnas.95.3.1195openalex-snapshot
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
inferredcites →https://doi.org/10.1074/jbc.m900465200openalex-snapshot
Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase
inferredcites →https://doi.org/10.1080/15384101.2015.1120925openalex-snapshot
Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression
inferredcites →https://doi.org/10.1084/jem.183.2.651openalex-snapshot
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin.
inferredcites →https://doi.org/10.1093/bioinformatics/bti623openalex-snapshot
ROCR: visualizing classifier performance in R
inferredcites →https://doi.org/10.1093/bioinformatics/btq033openalex-snapshot
BEDTools: a flexible suite of utilities for comparing genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/btr064openalex-snapshot
FIMO: scanning for occurrences of a given motif
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/bioinformatics/btv098openalex-snapshot
Sambamba: fast processing of NGS alignment formats
inferredcites →https://doi.org/10.1093/bioinformatics/btv145openalex-snapshot
ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
inferredcites →https://doi.org/10.1093/bioinformatics/btv735openalex-snapshot
DNAshapeR: an R/Bioconductor package for DNA shape prediction and feature encoding
inferredcites →https://doi.org/10.1093/emboj/17.19.5744openalex-snapshot
Expression of the LIM‐homeobox gene LH2 generates immortalized Steel factor‐dependent multipotent hematopoietic precursors
inferredcites →https://doi.org/10.1093/nar/gkv1002openalex-snapshot
dbSUPER: a database of super-enhancers in mouse and human genome
inferredcites →https://doi.org/10.1093/nar/gkv1191openalex-snapshot
csaw: a Bioconductor package for differential binding analysis of ChIP-seq data using sliding windows
inferredcites →https://doi.org/10.1101/cshperspect.a011536openalex-snapshot
The Structure and Function of the Eukaryotic Ribosome
inferredcites →https://doi.org/10.1101/gad.241422.114openalex-snapshot
Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
inferredcites →https://doi.org/10.1101/gad.281964.116openalex-snapshot
The second decade of 3C technologies: detailed insights into nuclear organization
inferredcites →https://doi.org/10.1101/gad.385606openalex-snapshot
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK
inferredcites →https://doi.org/10.1101/gr.184986.114openalex-snapshot
Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin
inferredcites →https://doi.org/10.1101/gr.185272.114openalex-snapshot
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements
inferredcites →https://doi.org/10.1101/gr.200733.115openalex-snapshot
Interactions between pluripotency factors specifycis-regulation in embryonic stem cells
inferredcites →https://doi.org/10.1101/gr.212803.116openalex-snapshot
Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes
inferredcites →https://doi.org/10.1111/j.1538-7836.2009.03398.xopenalex-snapshot
Regulation of megakaryocyte maturation and platelet formation
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Regression Shrinkage and Selection Via the Lasso
inferredcites →https://doi.org/10.1126/science.1181369openalex-snapshot
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
inferredcites →https://doi.org/10.1146/annurev.biochem.79.081507.103945openalex-snapshot
Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors
inferredcites →https://doi.org/10.1182/blood-2005-08-3145openalex-snapshot
The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation
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Critical roles for c-Myb in lymphoid priming and early B-cell development
inferredcites →https://doi.org/10.1182/blood-2014-12-570200openalex-snapshot
Hematopoietic stem cells: concepts, definitions, and the new reality
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Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model
inferredcites →https://doi.org/10.1182/blood.v92.1.4.413k38_4_10openalex-snapshot
Role of c-mpl in Early Hematopoiesis
inferredcites →https://doi.org/10.1186/1471-2202-15-2openalex-snapshot
Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine
inferredcites →https://doi.org/10.1186/1471-2202-15-95openalex-snapshot
Sox2 acts as a transcriptional repressor in neural stem cells
inferredcites →https://doi.org/10.1186/gb-2008-9-9-r137openalex-snapshot
Model-based Analysis of ChIP-Seq (MACS)
inferredcites →https://doi.org/10.1186/s12864-015-2140-xopenalex-snapshot
GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13059-015-0727-9openalex-snapshot
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
inferredcites →https://doi.org/10.1186/s13059-015-0730-1openalex-snapshot
Getting the genome in shape: the formation of loops, domains and compartments
inferredcites →https://doi.org/10.1186/s13059-015-0831-xopenalex-snapshot
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing
inferredcites →https://doi.org/10.1186/s13059-016-0992-2openalex-snapshot
CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data
inferredcites →https://doi.org/10.1371/journal.pcbi.1003419openalex-snapshot
Combinatorial Modeling of Chromatin Features Quantitatively Predicts DNA Replication Timing in Drosophila
inferredcites →https://doi.org/10.15252/embj.201592383openalex-snapshot
Cytokine‐induced megakaryocytic differentiation is regulated by genome‐wide loss of a uSTAT transcriptional program
inferredcites →https://doi.org/10.15252/embj.201592404openalex-snapshot
Dissection of transcriptional and cis‐regulatory control of differentiation in human pancreatic cancer
inferredcites →https://doi.org/10.15252/embj.201593324openalex-snapshot
Putting chromatin in its place: the pioneer factor NeuroD1 modulates chromatin state to drive cell fate decisions
inferredcites →https://doi.org/10.15252/embj.201798004openalex-snapshot
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins
inferredcites →https://doi.org/10.18637/jss.v033.i01openalex-snapshot
Regularization Paths for Generalized Linear Models via Coordinate Descent
inferredcites →https://doi.org/10.4049/jimmunol.0901187openalex-snapshot
c-Myb Is Required for Pro-B Cell Differentiation
inferredcites →https://doi.org/10.4161/cc.10.10.15619openalex-snapshot
Thrombopoietin and hematopoietic stem cells
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Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag
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Long-range enhancer–promoter contacts in gene expression control
inferred← citeshttps://doi.org/10.1101/2022.03.22.485307openalex-snapshot
A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification
inferred← citeshttps://doi.org/10.1126/sciimmunol.abj9836openalex-snapshot
FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression
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Molecular Basis of the Function of Transcriptional Enhancers
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