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Resolving systematic errors in widely-used enhancer activity assays in human cells enables genome-wide functional enhancer characterization

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Mechanisms by which transcription factors gain access to target sequence elements in chromatin

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An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS

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Enhancers as information integration hubs in development: lessons from genomics

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High throughput technologies for the functional discovery of mammalian enhancers: New approaches for understanding transcriptional regulatory network dynamics

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Small molecule inhibitors of the RNA-dependent protein kinase

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Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines

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Near-optimal probabilistic RNA-seq quantification

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Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution

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Genome-wide mapping of autonomous promoter activity in human cells

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IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

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Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

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Genome-wide characterization of mammalian promoters with distal enhancer functions

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DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

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Transposable elements have rewired the core regulatory network of human embryonic stem cells

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Induction of an interferon response by RNAi vectors in mammalian cells

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Rational design of a super core promoter that enhances gene expression

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Transcription by RNA polymerase III: more complex than we thought

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Transcriptional enhancers: from properties to genome-wide predictions

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Histone H3K27ac separates active from poised enhancers and predicts developmental state

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Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses

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Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines.

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Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1

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Java Treeview—extensible visualization of microarray data

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i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly

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Ensembl 2017

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inferredcites →https://doi.org/10.1101/gr.212092.116openalex-snapshot

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inferredcites →https://doi.org/10.1126/science.1232542openalex-snapshot

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inferredcites →https://doi.org/10.1126/science.aad5497openalex-snapshot

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

inferredcites →https://doi.org/10.1128/jvi.01781-15openalex-snapshot

Knockout of cGAS and STING Rescues Virus Infection of Plasmid DNA-Transfected Cells

inferredcites →https://doi.org/10.1128/jvi.02608-14openalex-snapshot

Unabated Adenovirus Replication following Activation of the cGAS/STING-Dependent Antiviral Response in Human Cells

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A Mechanism by which Adenovirus Virus-Associated RNAI Controls Translation in a Transient Expression Assay

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The Developmental Control of Transposable Elements and the Evolution of Higher Species

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Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Chromatin architecture reorganisation during neuronal cell differentiation in Drosophila genome

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Unbiased genome-scale identification of cis -regulatory modules in the human genome by GRAMc

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Functional mapping of androgen receptor enhancer activity

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