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Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies multiple variants including CADM2 and APOE

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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What keeps a body moving? The brain-derived neurotrophic factor val66met polymorphism and intrinsic motivation to exercise in humans

inferredcites →https://doi.org/10.1007/s12263-014-0415-5openalex-snapshot

Heritability and genetic etiology of habitual physical activity: a twin study with objective measures

inferredcites →https://doi.org/10.1016/j.ajhg.2014.07.014openalex-snapshot

Gene-Environment Dependence Creates Spurious Gene-Environment Interaction

inferredcites →https://doi.org/10.1016/j.ajhg.2014.12.021openalex-snapshot

Adjusting for Heritable Covariates Can Bias Effect Estimates in Genome-Wide Association Studies

inferredcites →https://doi.org/10.1016/j.ajhg.2015.12.019openalex-snapshot

A Robust Example of Collider Bias in a Genetic Association Study

inferredcites →https://doi.org/10.1016/j.heliyon.2017.e00349openalex-snapshot

Replication and characterization of CADM2 and MSRA genes on human behavior

inferredcites →https://doi.org/10.1016/j.metabol.2003.09.010openalex-snapshot

Apolipoprotein e genotype and changes in serum lipids and maximal oxygen uptake with exercise training

inferredcites →https://doi.org/10.1016/s0140-6736(12)60735-1openalex-snapshot

Correlates of physical activity: why are some people physically active and others not?

inferredcites →https://doi.org/10.1016/s1474-4422(05)70198-8openalex-snapshot

Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

inferredcites →https://doi.org/10.1037/e525162010-001openalex-snapshot

Physical Activity and Health: A Report of the Surgeon General

inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot

Biological insights from 108 schizophrenia-associated genetic loci

inferredcites →https://doi.org/10.1038/nature14132openalex-snapshot

New genetic loci link adipose and insulin biology to body fat distribution

inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot

Genetic studies of body mass index yield new insights for obesity biology

inferredcites →https://doi.org/10.1038/nature14962openalex-snapshot

The UK10K project identifies rare variants in health and disease

inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot

An atlas of genetic correlations across human diseases and traits

inferredcites →https://doi.org/10.1038/ng.3551openalex-snapshot

Physical and neurobehavioral determinants of reproductive onset and success

inferredcites →https://doi.org/10.1038/ng.3643openalex-snapshot

A reference panel of 64,976 haplotypes for genotype imputation

inferredcites →https://doi.org/10.1038/ng.943openalex-snapshot

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

inferredcites →https://doi.org/10.1038/ng1017-1558copenalex-snapshot

Erratum: Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

inferredcites →https://doi.org/10.1038/s41467-017-01261-5openalex-snapshot

Functional mapping and annotation of genetic associations with FUMA

inferredcites →https://doi.org/10.1079/phn2005840openalex-snapshot

Criterion-related validity of the last 7-day, short form of the International Physical Activity Questionnaire in Swedish adults

inferredcites →https://doi.org/10.1093/ajcn/36.5.936openalex-snapshot

A short questionnaire for the measurement of habitual physical activity in epidemiological studies

inferredcites →https://doi.org/10.1093/ajcn/82.6.1253openalex-snapshot

Genetic analysis of physical activity in twins

inferredcites →https://doi.org/10.1093/aje/kwi092openalex-snapshot

Physical Activity, APOE Genotype, and Dementia Risk: Findings from the Cardiovascular Health Cognition Study

inferredcites →https://doi.org/10.1093/bioinformatics/btw613openalex-snapshot

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

inferredcites →https://doi.org/10.1093/hmg/ddw433openalex-snapshot

Quantifying the extent to which index event biases influence large genetic association studies

inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a009003openalex-snapshot

Natural History of Leisure-time Physical Activity and Its Correlates: Associations with Mortality from All Causes and Cardiovascular Disease Over 28 Years

inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a115184openalex-snapshot

THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES

inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a115205openalex-snapshot

GENETIC AND ENVIRONMENTAL INFLUENCES ON LEVEL OF HABITUAL PHYSICAL ACTIVITY AND EXERCISE PARTICIPATION

inferredcites →https://doi.org/10.1097/00005768-199707000-00009openalex-snapshot

Physical activity and incidence of coronary heart disease in middle-aged women and men

inferredcites →https://doi.org/10.1097/00005768-199708000-00012openalex-snapshot

Familial determinants of moderate and intense physical activity: a twin study

inferredcites →https://doi.org/10.1097/00005768-200212000-00020openalex-snapshot

Correlates of adults??? participation in physical activity: review and update

inferredcites →https://doi.org/10.1101/166298openalex-snapshot

Genome-wide genetic data on ~500,000 UK Biobank participants

inferredcites →https://doi.org/10.1101/177014openalex-snapshot

Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort

inferredcites →https://doi.org/10.1111/gbb.12006openalex-snapshot

Sensation‐seeking genes and physical activity in youth

inferredcites →https://doi.org/10.1111/j.1520-037x.2006.04367.xopenalex-snapshot

Angiotensin‐Converting Enzyme Genotype and Adherence to Aerobic Exercise Training

inferredcites →https://doi.org/10.1111/j.1749-6632.2011.06102.xopenalex-snapshot

Practical issues in genome‐wide association studies for physical activity

inferredcites →https://doi.org/10.1111/obr.12089openalex-snapshot

Genetic factors in exercise adoption, adherence and obesity

inferredcites →https://doi.org/10.1126/science.1262110openalex-snapshot

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

inferredcites →https://doi.org/10.1136/bjsm.2009.059360openalex-snapshot

Concussion sans frontières

inferredcites →https://doi.org/10.1136/jech.55.2.149openalex-snapshot

Area based measures of social and economic circumstances: cause specific mortality patterns depend on the choice of index: Table 1

inferredcites →https://doi.org/10.1152/physiol.00019.2013openalex-snapshot

Exercise is the Real Polypill

inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot

Second-generation PLINK: rising to the challenge of larger and richer datasets

inferredcites →https://doi.org/10.1186/s40798-015-0036-6openalex-snapshot

Obesity-Related Genetic Variants and their Associations with Physical Activity

inferredcites →https://doi.org/10.1212/wnl.43.8.1467openalex-snapshot

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

inferredcites →https://doi.org/10.1249/01.mss.0000078924.61453.fbopenalex-snapshot

International Physical Activity Questionnaire: 12-Country Reliability and Validity

inferredcites →https://doi.org/10.1249/mss.0000000000000289openalex-snapshot

Age Group Comparability of Raw Accelerometer Output from Wrist- and Hip-Worn Monitors

inferredcites →https://doi.org/10.1249/mss.0b013e3181a2f646openalex-snapshot

Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults

inferredcites →https://doi.org/10.1371/journal.pgen.1006125openalex-snapshot

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

inferredcites →https://doi.org/10.1371/journal.pmed.1001618openalex-snapshot

Assessing Causality in the Association between Child Adiposity and Physical Activity Levels: A Mendelian Randomization Analysis

inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

inferredcites →https://doi.org/10.1371/journal.pone.0000022openalex-snapshot

Genetic Influences on Exercise Participation in 37.051 Twin Pairs from Seven Countries

inferredcites →https://doi.org/10.1371/journal.pone.0169649openalex-snapshot

Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study

inferredcites →https://doi.org/10.1375/136905203770326402openalex-snapshot

Heritability of Adult Body Height: A Comparative Study of Twin Cohorts in Eight Countries

inferredcites →https://doi.org/10.1534/g3.111.001198openalex-snapshot

Genotype Imputation with Thousands of Genomes

inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot

R: A Language and Environment for Statistical Computing

inferredcites →https://doi.org/10.3389/fnagi.2014.00061openalex-snapshot

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

inferredcites →https://doi.org/10.3945/ajcn.113.069849openalex-snapshot

Heritability of objectively assessed daily physical activity and sedentary behavior

inferredcites →https://doi.org/10.3945/jn.110.127290openalex-snapshot

Current Understanding of the Genetic Basis for Physical Activity

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1017/thg.2021.6openalex-snapshot

Genetic and Environmental Influences on Vigorous Exercise in South Korean Adolescent and Young Adult Twins

inferred← citeshttps://doi.org/10.1038/s41467-018-07743-4openalex-snapshot

GWAS identifies 14 loci for device-measured physical activity and sleep duration

inferred← citeshttps://doi.org/10.1038/s41467-020-14389-8openalex-snapshot

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

inferred← citeshttps://doi.org/10.1111/obr.12742openalex-snapshot

Revisiting the evolutionary origins of obesity: lazy versus peppy‐thrifty genotype hypothesis

inferred← citeshttps://doi.org/10.1136/bjsports-2017-098995openalex-snapshot

Physical activity and longevity: how to move closer to causal inference

inferred← citeshttps://doi.org/10.1136/bmjment-2022-300555openalex-snapshot

Examining the Lancet Commission risk factors for dementia using Mendelian randomisation

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