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Evolutionary causes of lifespan extension by dietary restriction: linking theory and mechanisms

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Human genetic diversity: Lewontin's fallacy
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Why do the well‐fed appear to die young?
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Costing reproduction
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High-Throughput and Longitudinal Analysis of Aging and Senescent Decline in Caenorhabditis elegans
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Sex and Death: What Is the Connection?
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Promoting Health and Longevity through Diet: From Model Organisms to Humans
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Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
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Inactivation of the Autophagy Gene bec-1 Triggers Apoptotic Cell Death in C. elegans
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Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death
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SID-5 Is an Endosome-Associated Protein Required for Efficient Systemic RNAi in C. elegans
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A Non-Cell-Autonomous Role of BEC-1/BECN1/Beclin1 in Coordinating Cell-Cycle Progression and Stem Cell Proliferation during Germline Development
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Survival costs of reproduction in Drosophila
inferredcites →https://doi.org/10.1016/j.ydbio.2018.04.009openalex-snapshot
Autophagy in C. elegans development
inferredcites →https://doi.org/10.1016/s0169-5347(00)02032-2openalex-snapshot
Molecular signals versus the Loi de Balancement
inferredcites →https://doi.org/10.1038/nature05904openalex-snapshot
Two neurons mediate diet-restriction-induced longevity in C. elegans
inferredcites →https://doi.org/10.1038/nature08980openalex-snapshot
The genetics of ageing
inferredcites →https://doi.org/10.1038/nrm1660openalex-snapshot
Autophagy in metazoans: cell survival in the land of plenty
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Both overlapping and independent mechanisms determine how diet and insulin-ligand knockouts extend lifespan of Drosophila melanogaster
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Autophagy as a promoter of longevity: insights from model organisms
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Facing up to the global challenges of ageing
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Moving beyond P values: data analysis with estimation graphics
inferredcites →https://doi.org/10.1038/s41598-018-24146-zopenalex-snapshot
Calorie restriction is the most reasonable anti-ageing intervention: a meta-analysis of survival curves
inferredcites →https://doi.org/10.1038/sj.cdd.4402115openalex-snapshot
The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans
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C. elegans : des neurones et des gènes
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THE GENETICS OF CAENORHABDITIS ELEGANS
inferredcites →https://doi.org/10.1093/gerona/gly070openalex-snapshot
Evolution Under Dietary Restriction Decouples Survival From Fecundity in Drosophila melanogaster Females
inferredcites →https://doi.org/10.1098/rspb.2015.2726openalex-snapshot
Evolution under dietary restriction increases male reproductive performance without survival cost
inferredcites →https://doi.org/10.1098/rspb.2019.1604openalex-snapshot
Evolution of ageing as a tangle of trade-offs: energy versus function
inferredcites →https://doi.org/10.1111/1365-2435.13418openalex-snapshot
Dietary restriction and insulin‐like signalling pathways as adaptive plasticity: A synthesis and re‐evaluation
inferredcites →https://doi.org/10.1111/j.0014-3820.2000.tb00076.xopenalex-snapshot
CALORIE RESTRICTION AND AGING: A LIFE-HISTORY ANALYSIS
inferredcites →https://doi.org/10.1111/j.0014-3820.2001.tb00841.xopenalex-snapshot
CAN EXPERIMENTS ON CALORIC RESTRICTION BE RECONCILED WITH THE DISPOSABLE SOMA THEORY FOR THE EVOLUTION OF SENESCENCE?
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Caenorhabditis elegans integrates food and reproductive signals in lifespan determination
inferredcites →https://doi.org/10.1111/j.1474-9726.2011.00707.xopenalex-snapshot
dFOXO‐independent effects of reduced insulin‐like signaling in Drosophila
inferredcites →https://doi.org/10.1111/j.1474-9726.2012.00798.xopenalex-snapshot
Comparative and meta‐analytic insights into life extension via dietary restriction
inferredcites →https://doi.org/10.1111/j.1558-5646.1957.tb02873.xopenalex-snapshot
NATURAL SELECTION OF INDIVIDUALLY HARMFUL SOCIAL ADAPTATIONS AMONG SIBS WITH SPECIAL REFERENCE TO SOCIAL INSECTS
inferredcites →https://doi.org/10.1111/j.2041-210x.2010.00012.xopenalex-snapshot
Simple means to improve the interpretability of regression coefficients
inferredcites →https://doi.org/10.1126/science.1087782openalex-snapshot
Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
inferredcites →https://doi.org/10.1126/science.1172539openalex-snapshot
Extending Healthy Life Span—From Yeast to Humans
inferredcites →https://doi.org/10.1126/science.290.5497.1717openalex-snapshot
Autophagy as a Regulated Pathway of Cellular Degradation
inferredcites →https://doi.org/10.1146/annurev-physiol-030212-183712openalex-snapshot
Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts
inferredcites →https://doi.org/10.1146/annurev.biochem.77.061206.171059openalex-snapshot
Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
inferredcites →https://doi.org/10.1152/physiol.00010.2005openalex-snapshot
Genomes Optimize Reproduction: Aging as a Consequence of the Developmental Program
inferredcites →https://doi.org/10.1186/gb-2000-2-1-research0002openalex-snapshot
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pgen.0040024openalex-snapshot
A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
inferredcites →https://doi.org/10.1371/journal.pone.0088828openalex-snapshot
C. elegans CEP-1/p53 and BEC-1 Are Involved in DNA Repair
inferredcites →https://doi.org/10.1534/genetics.115.175851openalex-snapshot
Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans
inferredcites →https://doi.org/10.1534/genetics.166.1.161openalex-snapshot
eat-2 and eat-18 Are Required for Nicotinic Neurotransmission in the Caenorhabditis elegans Pharynx
inferredcites →https://doi.org/10.18632/aging.100665openalex-snapshot
Target of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration
inferredcites →https://doi.org/10.18637/jss.v067.i01openalex-snapshot
Fitting Linear Mixed-Effects Models Using lme4
inferredcites →https://doi.org/10.18637/jss.v082.i13openalex-snapshot
lmerTest Package: Tests in Linear Mixed Effects Models
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing
inferredcites →https://doi.org/10.3389/fcell.2019.00308openalex-snapshot
Agephagy – Adapting Autophagy for Health During Aging
inferredcites →https://doi.org/10.4161/auto.3636openalex-snapshot
Autophagy Regulates Ageing inC. elegans
inferredcites →https://doi.org/10.4161/auto.4989openalex-snapshot
Autophagy is Required for Dietary Restriction-Mediated Life Span Extension inC. elegans
inferredcites →https://doi.org/10.4161/auto.5618openalex-snapshot
Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans
inferredcites →https://doi.org/10.4161/auto.5670openalex-snapshot
Regulation of cell growth by autophagy
inferredcites →https://doi.org/10.4161/auto.7.4.14391openalex-snapshot
The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy inC. elegans

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1111/evo.14146openalex-snapshot
Testing evolutionary explanations for the lifespan benefit of dietary restriction in fruit flies ( Drosophila melanogaster )
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