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LC/MS-QToF Profiling, Anti-Diabetic and Anti-Adipogenic potential of Divya MadhuKalp: A Novel Herbo-mineral Formulation

https://doi.org/10.1101/2020.02.15.950865

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Inhibitory Effect of Gallic Acid on Advanced Glycation End Products Induced Up-Regulation of Inflammatory Cytokines and Matrix Proteins in H9C2 (2-1) Cells

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Jamun ( Syzygium cumini ) seed and fruit extract attenuate hyperglycemia in diabetic rats

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Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats

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Quercetin inhibits adipogenesis of muscle progenitor cells in vitro

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Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation

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Mechanisms of antidiabetic effects of flavonoid rutin

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Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes

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Action of corilagin on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats

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IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

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Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties

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Glycolytic enzyme inhibitory and antiglycation potential of rutin

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Inhibitory effect of mung bean extract and its constituents vitexin and isovitexin on the formation of advanced glycation endproducts

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Linolenic acid prevents early and advanced glycation end-products (AGEs) modification of albumin

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Calycosin protects HUVECs from advanced glycation end products-induced macrophage infiltration

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Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress

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Antidiabetic potential of polyherbal formulation DB14201: Preclinical development, safety and efficacy studies

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Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose

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Daidzein promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and improves glucose homeostasis in Type 2 diabetic model mice

inferredcites →https://doi.org/10.1016/j.nutres.2014.12.009openalex-snapshot

Myricetin suppresses differentiation of 3 T3-L1 preadipocytes and enhances lipolysis in adipocytes

inferredcites →https://doi.org/10.1016/j.phymed.2015.01.003openalex-snapshot

Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro

inferredcites →https://doi.org/10.1016/j.phytochem.2015.02.029openalex-snapshot

Hypoglycemic activity of withanolides and elicitated Withania somnifera

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Stearidonic and γ-linolenic acids in echium oil improves glucose disposal in insulin resistant monkeys

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Phytochemistry of medicinal plants

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Medicinal plants of India with anti-diabetic potential

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Antioxidant phytochemicals against type 2 diabetes

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Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review

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Quercetin Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal and Glyoxal

inferredcites →https://doi.org/10.1038/nm.4145openalex-snapshot

Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice

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Potential Dual Role of Eugenol in Inhibiting Advanced Glycation End Products in Diabetes: Proteomic and Mechanistic Insights

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Cocoa tea (Camellia ptilophylla) water extract inhibits adipocyte differentiation in mouse 3T3-L1 preadipocytes

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Vitexin ameliorates high fat diet-induced obesity in male C57BL/6J mice via the AMPKα-mediated pathway

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Caffeic acid methyl and ethyl esters exert potential antidiabetic effects on glucose and lipid metabolism in cultured murine insulin-sensitive cells through mechanisms implicating activation of AMPK

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Myricetin: a potent approach for the treatment of type 2 diabetes as a natural class B GPCR agonist

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The effect of alpha-linolenic acid on glycemic control in individuals with type 2 diabetes

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Health Benefits of Punicic Acid: A Review

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Genistein and daidzein repress adipogenic differentiation of human adipose tissue‐derived mesenchymal stem cells via Wnt/β‐catenin signalling or lipolysis

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Evaluation of Antiobesity Effect of Mangiferin in Adipogenesis-Induced Human Mesenchymal Stem Cells by Assessing Adipogenic Genes

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Ferulic acid exerts its antidiabetic effect by modulating insulin-signalling molecules in the liver of high-fat diet and fructose-induced type-2 diabetic adult male rat

inferredcites →https://doi.org/10.1139/cjpp-2015-0073openalex-snapshot

Mangiferin suppressed advanced glycation end products (AGEs) through NF-κB deactivation and displayed anti-inflammatory effects in streptozotocin and high fat diet-diabetic cardiomyopathy rats

inferredcites →https://doi.org/10.1155/2010/858735openalex-snapshot

Apocynin Improves Insulin Resistance through Suppressing Inflammation in High-Fat Diet-Induced Obese Mice

inferredcites →https://doi.org/10.1155/2011/195271openalex-snapshot

Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

inferredcites →https://doi.org/10.1155/2012/674142openalex-snapshot

Shilajit : A Natural Phytocomplex with Potential Procognitive Activity

inferredcites →https://doi.org/10.1155/2013/549750openalex-snapshot

Naringenin Inhibits Adipogenesis and Reduces Insulin Sensitivity and Adiponectin Expression in Adipocytes

inferredcites →https://doi.org/10.1155/2014/846742openalex-snapshot

Baicalein Protects against Type 2 Diabetes via Promoting Isletβ-Cell Function in Obese Diabetic Mice

inferredcites →https://doi.org/10.1155/2018/9794625openalex-snapshot

Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities

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Catechin Treatment Ameliorates Diabetes and Its Complications in Streptozotocin-Induced Diabetic Rats

inferredcites →https://doi.org/10.1177/1934578x1100600211openalex-snapshot

α-Glucosidase Inhibitory Activity of Kaempferol-3- O -rutinoside

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Ascorbic acid enhances adipogenesis of 3T3-L1 murine preadipocyte through differential expression of collagens

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Quality assurance for Chinese herbal formulae: standardization of IBS-20, a 20-herb preparation

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Evidence based herbal drug standardization approach in coping with challenges of holistic management of diabetes: a dreadful lifestyle disorder of 21st century

inferredcites →https://doi.org/10.1186/s12944-017-0574-7openalex-snapshot

Suppression of adipocyte differentiation and lipid accumulation by stearidonic acid (SDA) in 3T3-L1 cells

inferredcites →https://doi.org/10.1186/s12967-017-1343-0openalex-snapshot

Phenolic compounds apigenin, hesperidin and kaempferol reduce in vitro lipid accumulation in human adipocytes

inferredcites →https://doi.org/10.1186/s12986-018-0310-yopenalex-snapshot

Gynura divaricata rich in 3, 5−/4, 5-dicaffeoylquinic acid and chlorogenic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice

inferredcites →https://doi.org/10.1194/jlr.m055798openalex-snapshot

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

inferredcites →https://doi.org/10.1210/en.2014-1354openalex-snapshot

Gallic Acid Regulates Body Weight and Glucose Homeostasis Through AMPK Activation

inferredcites →https://doi.org/10.1242/jcs.079699openalex-snapshot

Adipogenesis at a glance

inferredcites →https://doi.org/10.1371/journal.pone.0120842openalex-snapshot

Chlorogenic Acid Improves Late Diabetes through Adiponectin Receptor Signaling Pathways in db/db Mice

inferredcites →https://doi.org/10.1371/journal.pone.0126142openalex-snapshot

Regulation of Adipogenesis and Key Adipogenic Gene Expression by 1, 25-Dihydroxyvitamin D in 3T3-L1 Cells

inferredcites →https://doi.org/10.1371/journal.pone.0163640openalex-snapshot

Suppression of Very Early Stage Of Adipogenesis by Baicalein, a Plant-Derived Flavonoid through Reduced Akt-C/EBPα-GLUT4 Signaling-Mediated Glucose Uptake in 3T3-L1 Adipocytes

inferredcites →https://doi.org/10.1371/journal.pone.0218792openalex-snapshot

Withaferin A inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice

inferredcites →https://doi.org/10.21010/ajtcam.v13i3.15openalex-snapshot

DAIDZEIN: A REVIEW OF PHARMACOLOGICAL EFFECTS

inferredcites →https://doi.org/10.2174/092986710791299902openalex-snapshot

Anti-Diabetic Effect of Trigonelline and Nicotinic Acid, on KK-Ay Mice

inferredcites →https://doi.org/10.2174/0929867323666160909153707openalex-snapshot

The Antidiabetic Potential of Quercetin: Underlying Mechanisms

inferredcites →https://doi.org/10.2174/1573406411208030415openalex-snapshot

Synthesis and Antiglycation Activity of Kaempferol-3-O-rutinoside (Nicotiflorin)

inferredcites →https://doi.org/10.2174/1871530314666141111103217openalex-snapshot

Vitamins and Type 2 Diabetes Mellitus

inferredcites →https://doi.org/10.2337/db14-0006openalex-snapshot

Mangiferin Stimulates Carbohydrate Oxidation and Protects Against Metabolic Disorders Induced by High-Fat Diets

inferredcites →https://doi.org/10.2337/dc09-s302openalex-snapshot

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

inferredcites →https://doi.org/10.2337/diacare.26.3.625openalex-snapshot

Amino Acid Ingestion Strongly Enhances Insulin Secretion in Patients With Long-Term Type 2 Diabetes

inferredcites →https://doi.org/10.3109/00365513.2013.831470openalex-snapshot

Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced obesity mice

inferredcites →https://doi.org/10.3177/jnsv.49.56openalex-snapshot

Anti-Obesity Effects of a Mixture of Thiamin, Arginine, Caffeine, and Citric Acid in Non-Insulin Dependent Diabetic KK Mice

inferredcites →https://doi.org/10.3389/fphar.2015.00308openalex-snapshot

A Review of Swertia chirayita (Gentianaceae) as a Traditional Medicinal Plant

inferredcites →https://doi.org/10.3390/biom9030099openalex-snapshot

Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol

inferredcites →https://doi.org/10.3390/ijms10052367openalex-snapshot

Hypoglycaemic and Hypolipidaemic Effects of Withania somnifera Root and Leaf Extracts on Alloxan-Induced Diabetic Rats

inferredcites →https://doi.org/10.3390/ijms12106445openalex-snapshot

A Determination of Potential α-Glucosidase Inhibitors from Azuki Beans (Vigna angularis)

inferredcites →https://doi.org/10.3390/ijms141122697openalex-snapshot

Hyperoside Downregulates the Receptor for Advanced Glycation End Products (RAGE) and Promotes Proliferation in ECV304 Cells via the c-Jun N-Terminal Kinases (JNK) Pathway Following Stimulation by Advanced Glycation End-Products In Vitro

inferredcites →https://doi.org/10.3390/molecules20022786openalex-snapshot

Scopoletin Protects against Methylglyoxal-Induced Hyperglycemia and Insulin Resistance Mediated by Suppression of Advanced Glycation Endproducts (AGEs) Generation and Anti-Glycation

inferredcites →https://doi.org/10.3390/molecules21020226openalex-snapshot

Screening of Korean Natural Products for Anti-Adipogenesis Properties and Isolation of Kaempferol-3-O-rutinoside as a Potent Anti-Adipogenetic Compound from Solidago virgaurea

inferredcites →https://doi.org/10.3390/molecules21101305openalex-snapshot

Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity

inferredcites →https://doi.org/10.3390/molecules21101374openalex-snapshot

An Overview of Plant Phenolic Compounds and Their Importance in Human Nutrition and Management of Type 2 Diabetes

inferredcites →https://doi.org/10.3390/molecules22050745openalex-snapshot

Modulation of HO-1 by Ferulic Acid Attenuates Adipocyte Differentiation in 3T3-L1 Cells

inferredcites →https://doi.org/10.3390/molecules22071135openalex-snapshot

How Can Synergism of Traditional Medicines Benefit from Network Pharmacology?

inferredcites →https://doi.org/10.3390/molecules24061045openalex-snapshot

Phenolic Compounds Inhibit 3T3-L1 Adipogenesis Depending on the Stage of Differentiation and Their Binding Affinity to PPARγ

inferredcites →https://doi.org/10.3390/nu6083230openalex-snapshot

A Significant Inhibitory Effect on Advanced Glycation End Product Formation by Catechin as the Major Metabolite of Lotus Seedpod Oligomeric Procyanidins

inferredcites →https://doi.org/10.3390/nu7125514openalex-snapshot

Protective Effect of Vanillic Acid against Hyperinsulinemia, Hyperglycemia and Hyperlipidemia via Alleviating Hepatic Insulin Resistance and Inflammation in High-Fat Diet (HFD)-Fed Rats

inferredcites →https://doi.org/10.3390/nu8050305openalex-snapshot

Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice

inferredcites →https://doi.org/10.3892/ijmm.2017.3211openalex-snapshot

Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes

inferredcites →https://doi.org/10.3945/jn.110.125591openalex-snapshot

Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

inferredcites →https://doi.org/10.4103/0973-1296.160470openalex-snapshot

Luteolin is a bioflavonoid that attenuates adipocyte-derived inflammatory responses via suppression of nuclear factor-κB/mitogen-activated protein kinases pathway

inferredcites →https://doi.org/10.4103/0973-7847.134229openalex-snapshot

Polyherbal formulation: Concept of ayurveda

inferredcites →https://doi.org/10.4103/0976-0105.177703openalex-snapshot

A simple practice guide for dose conversion between animals and human

inferredcites →https://doi.org/10.4103/2231-4040.104713openalex-snapshot

Hypolipidemic effect of methanol fraction of Aconitum heterophyllum wall ex Royle and the mechanism of action in diet-induced obese rats

inferredcites →https://doi.org/10.5897/jmpr.9000710openalex-snapshot

Hypoglycaemic effect of Thymelaea hirsuta in normal and streptozotocin-induced diabetic rats

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/978-3-030-94753-8_50-1openalex-snapshot

Vitexin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology

inferred← citeshttps://doi.org/10.1007/978-3-030-94753-8_50-2openalex-snapshot

Vitexin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology

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