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Identification of the Molecular Basis of Anti-fibrotic Effects of Soluble Guanylate Cyclase Activator Using the Human Lung Fibroblast Phosphoproteome

https://doi.org/10.1101/2020.06.12.148908

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-1-60761-987-1_3openalex-snapshot

Analysis of Phosphoproteomics Data

inferredcites →https://doi.org/10.1016/j.cell.2006.09.026openalex-snapshot

Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks

inferredcites →https://doi.org/10.1016/j.celrep.2014.07.036openalex-snapshot

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

inferredcites →https://doi.org/10.1016/j.coph.2014.12.014openalex-snapshot

Renal effects of soluble guanylate cyclase stimulators and activators: A review of the preclinical evidence

inferredcites →https://doi.org/10.1016/j.niox.2018.03.008openalex-snapshot

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets

inferredcites →https://doi.org/10.1016/s0163-7258(98)00063-1openalex-snapshot

Delineation of Selective Cyclic GMP-Dependent Protein Kinase Iα Substrate and Inhibitor Peptides Based on Combinatorial Peptide Libraries on Paper

inferredcites →https://doi.org/10.1021/acs.analchem.5b04123openalex-snapshot

Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling

inferredcites →https://doi.org/10.1021/bi00033a032openalex-snapshot

Determination of Cyclic Nucleotide-Dependent Protein Kinase Substrate Specificity by the Use of Peptide Libraries on Cellulose Paper

inferredcites →https://doi.org/10.1021/cr000236lopenalex-snapshot

Physiological Substrates of cAMP-Dependent Protein Kinase

inferredcites →https://doi.org/10.1038/cr.2008.328openalex-snapshot

Non-Smad pathways in TGF-β signaling

inferredcites →https://doi.org/10.1038/s41598-017-10716-0openalex-snapshot

Quantitative Phosphoproteomic Analysis Reveals Key Mechanisms of Cellular Proliferation in Liver Cancer Cells

inferredcites →https://doi.org/10.1038/s41598-018-27656-yopenalex-snapshot

The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats

inferredcites →https://doi.org/10.1055/s-0031-1296471openalex-snapshot

Nitric Oxide-independent Activation of Soluble Guanylate Cyclase by BAY 60-2770 in Experimental Liver Fibrosis

inferredcites →https://doi.org/10.1056/nejmoa1002110openalex-snapshot

A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis

inferredcites →https://doi.org/10.1056/nejmra1705751openalex-snapshot

Idiopathic Pulmonary Fibrosis

inferredcites →https://doi.org/10.1073/pnas.0805139105openalex-snapshot

A quantitative atlas of mitotic phosphorylation

inferredcites →https://doi.org/10.1074/jbc.271.8.4230openalex-snapshot

Characterization of ERK1 Activation Site Mutants and the Effect on Recognition by MEK1 and MEK2

inferredcites →https://doi.org/10.1074/jbc.272.44.27678openalex-snapshot

TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

inferredcites →https://doi.org/10.1074/jbc.272.44.28107openalex-snapshot

Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

inferredcites →https://doi.org/10.1074/jbc.m305676200openalex-snapshot

Glycogen Synthase Kinase-3β Regulates NF-κB1/p105 Stability

inferredcites →https://doi.org/10.1074/jbc.m411130200openalex-snapshot

Endothelin 1 Induces β1Pix Translocation and Cdc42 Activation via Protein Kinase A-dependent Pathway

inferredcites →https://doi.org/10.1111/bph.14137openalex-snapshot

The soluble guanylate cyclase stimulator IW‐1973 prevents inflammation and fibrosis in experimental non‐alcoholic steatohepatitis

inferredcites →https://doi.org/10.1111/hepr.12885openalex-snapshot

Non‐alcoholic fatty liver disease phosphoproteomics: A functional piece of the precision puzzle

inferredcites →https://doi.org/10.1111/j.1538-7836.2010.03806.xopenalex-snapshot

Nitric oxide‐sensitive guanylyl cyclase is the only nitric oxide receptor mediating platelet inhibition

inferredcites →https://doi.org/10.1111/j.1538-7836.2011.04576.xopenalex-snapshot

Novel roles of cAMP/cGMP‐dependent signaling in platelets

inferredcites →https://doi.org/10.1124/pr.110.002907openalex-snapshot

cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action

inferredcites →https://doi.org/10.1136/annrheumdis-2011-200862openalex-snapshot

Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis

inferredcites →https://doi.org/10.1136/annrheumdis-2013-204508openalex-snapshot

Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling

inferredcites →https://doi.org/10.1164/rccm.201006-0894ciopenalex-snapshot

Clinical Course and Prediction of Survival in Idiopathic Pulmonary Fibrosis

inferredcites →https://doi.org/10.1182/blood-2016-05-714048openalex-snapshot

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition

inferredcites →https://doi.org/10.1183/09031936.01.17509540openalex-snapshot

Quality of life of idiopathic pulmonary fibrosis patients

inferredcites →https://doi.org/10.1186/gb-2006-7-6-r50openalex-snapshot

Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system

inferredcites →https://doi.org/10.1242/jcs.02554openalex-snapshot

Non-Smad TGF-β signals

inferredcites →https://doi.org/10.1378/chest.10-2572openalex-snapshot

Long-term Course and Prognosis of Idiopathic Pulmonary Fibrosis in the New Millennium

inferredcites →https://doi.org/10.1378/chest.128.4.2393openalex-snapshot

Pulmonary Hypertension in Patients With Idiopathic Pulmonary Fibrosis

inferredcites →https://doi.org/10.1378/chest.129.3.746openalex-snapshot

Prevalence and Outcomes of Pulmonary Arterial Hypertension in Advanced Idiopathic Pulmonary Fibrosis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3390/molecules27113452openalex-snapshot

Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis

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