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Gut bacteria convert cortisol into a distinct host signalling molecule
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Scalable molecular dynamics with NAMD
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The First Crystal Structure of l-Threonine Dehydrogenase
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11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?
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11β-hydroxyandrostenedione: Downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways
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Molecular dynamics simulations of large macromolecular complexes
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17-Hydroxylase/C17,20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolites
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Glucocorticoids and gut bacteria: “The GALF Hypothesis” in the metagenomic era
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Interaction between L-threonine dehydrogenase and aminoacetone synthetase and mechanism of aminoacetone production.
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Degradation of steroids in the human gut
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Purification and characterization of a novel 17 alpha-hydroxysteroid dehydrogenase from an intestinal Eubacterium sp. VPI 12708.
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Basic Local Alignment Search Tool
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Macromolecular TLS Refinement in REFMAC at Moderate Resolutions
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The refined three-dimensional structure of 3α,20β-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
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Extended Adaptive Biasing Force Algorithm. An On-the-Fly Implementation for Accurate Free-Energy Calculations
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Structure of Bacterial 3β/17β-Hydroxysteroid Dehydrogenase at 1.2 Å Resolution: A Model for Multiple Steroid Recognition ,
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Crystal Structure of a Ternary Complex of the Alcohol Dehydrogenase from Sulfolobus solfataricus,
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NAMD goes quantum: an integrative suite for hybrid simulations
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A reference gene catalogue of the pig gut microbiome
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Immune regulation by glucocorticoids
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GABA-modulating bacteria of the human gut microbiota
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11-Oxygenated androgens in health and disease
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Mapping human microbiome drug metabolism by gut bacteria and their genes
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Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing
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QwikMD — Integrative Molecular Dynamics Toolkit for Novices and Experts
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Purification and characterization of a novel dimeric 20 α-hydroxysteroid dehydrogenase from Tetrahymena pyriformis
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Active site dynamics in the zinc-dependent medium chain alcohol dehydrogenase superfamily
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Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I
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Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32
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Molecular dynamics study of biomembrane/local anesthetics interactions
inferredcites →https://doi.org/10.1080/00268976.2013.813594openalex-snapshot
Using collective variables to drive molecular dynamics simulations
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Density functional and molecular dynamics simulations of local anesthetics in 0.9% NaCl solution
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Dynamical behaviour of the human β1-adrenoceptor under agonist binding
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Clinical significance of 11-oxygenated androgens
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Some aspects of quantitative analysis and correction of radiation damage
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Experimental phasing with SHELXC/D/E: combining chain tracing with density modification
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Integration, scaling, space-group assignment and post-refinement
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Refinement of Macromolecular Structures by the Maximum-Likelihood Method
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Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
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Computational Methodologies for Real-Space Structural Refinement of Large Macromolecular Complexes
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Role of gut metabolism of adrenal corticosteroids and hypertension: clues gut-cleansing antibiotics give us
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inferredcites →https://doi.org/10.1194/jlr.m083949openalex-snapshot
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URINARY EXCRETION OF 17-KETOSTEROIDS FOLLOWING RECTAL INFUSION OF CORTISOL
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11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored
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Microbiota-Gut-Brain Axis: Modulator of Host Metabolism and Appetite
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1016/j.jbc.2023.105596openalex-snapshot
Specific residues and conformational plasticity define the substrate specificity of short-chain dehydrogenases/reductases
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111174openalex-snapshot
Gut feelings about bacterial steroid-17,20-desmolase
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Completion of the gut microbial epi-bile acid pathway
inferred← citeshttps://doi.org/10.1101/2024.06.09.598130openalex-snapshot
An expanded metabolic pathway for androgen production by host-associated bacteria
inferred← citeshttps://doi.org/10.1128/aem.00641-20openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fpls.2023.1159394openalex-snapshot
Genome-wide analysis revealed the stepwise origin and functional diversification of HSDs from lower to higher plant species
inferred← citeshttps://doi.org/10.3390/microorganisms9030469openalex-snapshot
Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega
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