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Single-cell analyses of the corneal epithelium: Unique cell types and gene expression profiles

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/dvdy.10097openalex-snapshot
Characterizing gene expression during lens formation in Xenopus laevis: Evaluating the model for embryonic lens induction
inferredcites →https://doi.org/10.1002/dvdy.147openalex-snapshot
Modeling ocular lens disease in Xenopus
inferredcites →https://doi.org/10.1002/dvdy.24179openalex-snapshot
The vertebrate corneal epithelium: From early specification to constant renewal
inferredcites →https://doi.org/10.1002/dvg.23001openalex-snapshot
What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia
inferredcites →https://doi.org/10.1002/dvg.23003openalex-snapshot
Seeing the future: using Xenopus to understand eye regeneration
inferredcites →https://doi.org/10.1002/jez.1401540105openalex-snapshot
Lens regeneration from the cornea in Xenopus laevis
inferredcites →https://doi.org/10.1002/jez.a.10275openalex-snapshot
Tissue interactions and lens‐forming competence in the outer cornea of larval Xenopus laevis
inferredcites →https://doi.org/10.1002/jez.a.138openalex-snapshot
Lens-forming competence in the epidermis ofXenopus laevis during development
inferredcites →https://doi.org/10.1002/stem.1840openalex-snapshot
Lineage Tracing of Stem and Progenitor Cells of the Murine Corneal Epithelium
inferredcites →https://doi.org/10.1002/stem.209openalex-snapshot
Stem Cell Activity in the Developing Human Cornea
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A Set of Novel Tadpole Specific Genes Expressed Only in the Epidermis Are Down-Regulated by Thyroid Hormone duringXenopus laevisMetamorphosis
inferredcites →https://doi.org/10.1006/dbio.1997.8598openalex-snapshot
Lens Regeneration in LarvalXenopus laevis:Experimental Analysis of the Decline in the Regenerative Capacity during Development
inferredcites →https://doi.org/10.1007/978-3-319-21702-4_2openalex-snapshot
The Mammalian Limbal Stem Cell Niche: A Complex Interaction Between Cells, Growth Factors and Extracellular Matrix
inferredcites →https://doi.org/10.1007/978-3-642-30406-4_19openalex-snapshot
Stem Cells and Corneal Epithelial Maintenance: Insights from the Mouse and Other Animal Models
inferredcites →https://doi.org/10.1016/0002-9394(77)90127-1openalex-snapshot
Posterior Amorphous Corneal Dystrophy
inferredcites →https://doi.org/10.1016/0092-8674(89)90958-6openalex-snapshot
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
inferredcites →https://doi.org/10.1016/b978-0-12-374169-1.00006-0openalex-snapshot
Xenopus, an Ideal Vertebrate System for Studies of Eye Development and Regeneration
inferredcites →https://doi.org/10.1016/j.cell.2008.12.043openalex-snapshot
Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2015.04.044openalex-snapshot
Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2015.05.002openalex-snapshot
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
inferredcites →https://doi.org/10.1016/j.celrep.2020.02.091openalex-snapshot
Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics
inferredcites →https://doi.org/10.1016/j.cels.2016.08.010openalex-snapshot
Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity
inferredcites →https://doi.org/10.1016/j.devcel.2008.01.017openalex-snapshot
Multiple Roles of Notch Signaling in the Regulation of Epidermal Development
inferredcites →https://doi.org/10.1016/j.ebiom.2017.10.024openalex-snapshot
Restricted Presence of POU6F2 in Human Corneal Endothelial Cells Uncovered by Extension of the Promoter-level Expression Atlas
inferredcites →https://doi.org/10.1016/j.exer.2003.09.008openalex-snapshot
Corneal epithelial stem cells at the limbus: looking at some old problems from a new angle
inferredcites →https://doi.org/10.1016/j.exer.2005.02.016openalex-snapshot
Identification and characterization of limbal stem cells
inferredcites →https://doi.org/10.1016/j.exer.2005.09.012openalex-snapshot
Corneal NF-κB activity is necessary for the retention of transparency in the cornea of UV-B-exposed transgenic reporter mice
inferredcites →https://doi.org/10.1016/j.exer.2013.07.021openalex-snapshot
The structure and development of Xenopus laevis cornea
inferredcites →https://doi.org/10.1016/j.exer.2016.01.003openalex-snapshot
Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling
inferredcites →https://doi.org/10.1016/j.exer.2016.08.013openalex-snapshot
The lens regenerative competency of limbal vs. central regions of mature Xenopus cornea epithelium
inferredcites →https://doi.org/10.1016/j.exer.2018.01.007openalex-snapshot
A model for investigating developmental eye repair in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.exer.2019.04.010openalex-snapshot
Molecular markers for corneal epithelial cells in larval vs. adult Xenopus frogs
inferredcites →https://doi.org/10.1016/j.exer.2019.107767openalex-snapshot
Understanding cornea homeostasis and wound healing using a novel model of stem cell deficiency in Xenopus
inferredcites →https://doi.org/10.1016/j.exer.2020.108062openalex-snapshot
Keratocyte biology
inferredcites →https://doi.org/10.1016/j.exer.2020.108094openalex-snapshot
Corneal epithelial biology: Lessons stemming from old to new
inferredcites →https://doi.org/10.1016/j.stem.2015.07.002openalex-snapshot
Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury
inferredcites →https://doi.org/10.1016/j.stemcr.2017.05.022openalex-snapshot
Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis
inferredcites →https://doi.org/10.1016/j.ydbio.2012.12.005openalex-snapshot
Expression of pluripotency factors in larval epithelia of the frog Xenopus: Evidence for the presence of cornea epithelial stem cells
inferredcites →https://doi.org/10.1016/j.ydbio.2013.12.036openalex-snapshot
Retinoic acid regulation by CYP26 in vertebrate lens regeneration
inferredcites →https://doi.org/10.1016/j.ydbio.2015.02.012openalex-snapshot
Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
inferredcites →https://doi.org/10.1016/j.ydbio.2016.04.009openalex-snapshot
Expanding the genetic toolkit in Xenopus: Approaches and opportunities for human disease modeling
inferredcites →https://doi.org/10.1016/j.ydbio.2016.09.017openalex-snapshot
Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis
inferredcites →https://doi.org/10.1016/s0074-7696(06)60005-3openalex-snapshot
Molecular Mechanism and Evolutional Significance of Epithelial–Mesenchymal Interactions in the Body‐ and Tail‐Dependent Metamorphic Transformation of Anuran Larval Skin
inferredcites →https://doi.org/10.1016/s0167-4781(00)00281-5openalex-snapshot
New epidermal keratin genes from Xenopus laevis: hormonal and regional regulation of their expression during anuran skin metamorphosis
inferredcites →https://doi.org/10.1016/s0925-4773(00)00419-6openalex-snapshot
Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation
inferredcites →https://doi.org/10.1034/j.1600-0749.2003.00064.xopenalex-snapshot
Isolation and Developmental Expression of Tyrosinase Family Genes in Xenopus laevis
inferredcites →https://doi.org/10.1038/229560a0openalex-snapshot
Role of the Pericorneal Papillary Structure in Renewal of Corneal Epithelium
inferredcites →https://doi.org/10.1038/75664openalex-snapshot
Mutations in KERA, encoding keratocan, cause cornea plana
inferredcites →https://doi.org/10.1038/eye.1989.22openalex-snapshot
Concept and application of limbal stem cells
inferredcites →https://doi.org/10.1038/nature07406openalex-snapshot
Oligopotent stem cells are distributed throughout the mammalian ocular surface
inferredcites →https://doi.org/10.1038/nature17997openalex-snapshot
Tracing haematopoietic stem cell formation at single-cell resolution
inferredcites →https://doi.org/10.1038/nature19840openalex-snapshot
Genome evolution in the allotetraploid frog Xenopus laevis
inferredcites →https://doi.org/10.1038/nature24489openalex-snapshot
A single-cell survey of the small intestinal epithelium
inferredcites →https://doi.org/10.1038/nbt.2859openalex-snapshot
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
inferredcites →https://doi.org/10.1038/nbt.3192openalex-snapshot
Spatial reconstruction of single-cell gene expression data
inferredcites →https://doi.org/10.1038/nbt.4096openalex-snapshot
Integrating single-cell transcriptomic data across different conditions, technologies, and species
inferredcites →https://doi.org/10.1038/nbt.4314openalex-snapshot
Dimensionality reduction for visualizing single-cell data using UMAP
inferredcites →https://doi.org/10.1038/ncomms14049openalex-snapshot
Massively parallel digital transcriptional profiling of single cells
inferredcites →https://doi.org/10.1038/ncomms5418openalex-snapshot
MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia
inferredcites →https://doi.org/10.1038/ng0697-184openalex-snapshot
Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy
inferredcites →https://doi.org/10.1038/nmeth.4463openalex-snapshot
SCENIC: single-cell regulatory network inference and clustering
inferredcites →https://doi.org/10.1038/s41467-020-14385-yopenalex-snapshot
Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
inferredcites →https://doi.org/10.1038/s41586-019-1085-7openalex-snapshot
Stem cell competition orchestrates skin homeostasis and ageing
inferredcites →https://doi.org/10.1038/s41598-017-04006-yopenalex-snapshot
Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers
inferredcites →https://doi.org/10.1038/s41598-017-04569-wopenalex-snapshot
Identification for Differential Localization of Putative Corneal Epithelial Stem Cells in Mouse and Human
inferredcites →https://doi.org/10.1038/s41598-019-46094-yopenalex-snapshot
Human Corneal Expression of SLC4A11, a Gene Mutated in Endothelial Corneal Dystrophies
inferredcites →https://doi.org/10.1038/sj.onc.1204326openalex-snapshot
Histone H3 phosphorylation and cell division
inferredcites →https://doi.org/10.1042/bj20120813openalex-snapshot
Lens and retina regeneration: new perspectives from model organisms
inferredcites →https://doi.org/10.1046/j.1432-0436.2001.680205.xopenalex-snapshot
Xenopus Na,K-ATPase: primary sequence of the β2 subunit and in situ localization of α1, β1, and γ expression during pronephric kidney development
inferredcites →https://doi.org/10.1073/pnas.1313491110openalex-snapshot
Keratins as the main component for the mechanical integrity of keratinocytes
inferredcites →https://doi.org/10.1073/pnas.1320301110openalex-snapshot
Nfatc1 orchestrates aging in hair follicle stem cells
inferredcites →https://doi.org/10.1073/pnas.1601569113openalex-snapshot
FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential
inferredcites →https://doi.org/10.1073/pnas.1713539115openalex-snapshot
Functional characterization of the mucus barrier on the Xenopus tropicalis skin surface
inferredcites →https://doi.org/10.1073/pnas.1914143116openalex-snapshot
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration
inferredcites →https://doi.org/10.1073/pnas.252774999openalex-snapshot
Tadpole skin dies autonomously in response to thyroid hormone at metamorphosis
inferredcites →https://doi.org/10.1074/jbc.m113.504399openalex-snapshot
The Ets Transcription Factor EHF as a Regulator of Cornea Epithelial Cell Identity
inferredcites →https://doi.org/10.1074/jbc.m117.793117openalex-snapshot
Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation
inferredcites →https://doi.org/10.1074/jbc.m600777200openalex-snapshot
Transcriptional Profiling of Enriched Populations of Stem Cells Versus Transient Amplifying Cells
inferredcites →https://doi.org/10.1083/jcb.103.1.49openalex-snapshot
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.
inferredcites →https://doi.org/10.1086/bblv221n1p137openalex-snapshot
FGF Signaling Is Required for Lens Regeneration in Xenopus laevis
inferredcites →https://doi.org/10.1091/mbc.e18-06-0373openalex-snapshot
14-3-3 targets keratin intermediate filaments to mechanically sensitive cell–cell contacts
inferredcites →https://doi.org/10.1091/mbc.e18-08-0496openalex-snapshot
Uroplakins play conserved roles in egg fertilization and acquired additional urothelial functions during mammalian divergence
inferredcites →https://doi.org/10.1093/bmb/ldr026openalex-snapshot
Stem cells of the human cornea
inferredcites →https://doi.org/10.1093/hmg/ddv063openalex-snapshot
Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model
inferredcites →https://doi.org/10.1093/nar/gkx936openalex-snapshot
Xenbase: a genomic, epigenomic and transcriptomic model organism database
inferredcites →https://doi.org/10.1101/gr.267013.120openalex-snapshot
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver
inferredcites →https://doi.org/10.1101/pdb.prot101535openalex-snapshot
Ex Vivo Eye Tissue Culture Methods for Xenopus
inferredcites →https://doi.org/10.1111/j.1087-0024.2004.09311.xopenalex-snapshot
Corneal Epithelial Stem Cells: Past, Present, and Future
inferredcites →https://doi.org/10.1111/j.1440-169x.2009.01100.xopenalex-snapshot
Molecular features of thyroid hormone‐regulated skin remodeling in Xenopus laevis during metamorphosis
inferredcites →https://doi.org/10.1111/j.1469-7580.2008.00891.xopenalex-snapshot
The lens‐regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression
inferredcites →https://doi.org/10.1111/j.1755-148x.2007.00420.xopenalex-snapshot
Mitf contributes to melanosome distribution and melanophore dendricity
inferredcites →https://doi.org/10.1111/vop.12147openalex-snapshot
Evaluation of ABCG 2 and p63 expression in canine cornea and cultivated corneal epithelial cells
inferredcites →https://doi.org/10.1111/vop.12651openalex-snapshot
Morphological and immunohistochemical characteristics of the equine corneal epithelium
inferredcites →https://doi.org/10.1126/science.aad4395openalex-snapshot
Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
inferredcites →https://doi.org/10.1126/science.aao4174openalex-snapshot
Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq
inferredcites →https://doi.org/10.1126/science.aar2131openalex-snapshot
Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease
inferredcites →https://doi.org/10.1126/science.aav9996openalex-snapshot
Identification of a regeneration-organizing cell in the Xenopus tail
inferredcites →https://doi.org/10.1128/mcb.20.18.6996-7006.2000openalex-snapshot
A Human Condensin Complex Containing hCAP-C–hCAP-E and CNAP1, a Homolog of Xenopus XCAP-D2, Colocalizes with Phosphorylated Histone H3 during the Early Stage of Mitotic Chromosome Condensation
inferredcites →https://doi.org/10.1136/bjo.86.7.729openalex-snapshot
A novel mutation in KRT12 associated with Meesmann's epithelial corneal dystrophy
inferredcites →https://doi.org/10.1155/2013/103947openalex-snapshot
Ocular Surface Development and Gene Expression
inferredcites →https://doi.org/10.1159/000490898openalex-snapshot
Xenopus: An Undervalued Model Organism to Study and Model Human Genetic Disease
inferredcites →https://doi.org/10.1167/iovs.03-0449openalex-snapshot
Postnatal Gene Expression in the Normal Mouse Cornea by SAGE
inferredcites →https://doi.org/10.1167/iovs.04-0804openalex-snapshot
Congenital Stromal Dystrophy of the Cornea Caused by a Mutation in the Decorin Gene
inferredcites →https://doi.org/10.1167/iovs.05-1500openalex-snapshot
SOD1 : A Candidate Gene for Keratoconus
inferredcites →https://doi.org/10.1167/iovs.07-1260openalex-snapshot
Acute Wound Healing in the Human Central Corneal Epithelium Appears to Be Independent of Limbal Stem Cell Influence
inferredcites →https://doi.org/10.1167/iovs.08-3046openalex-snapshot
Tight Junction Transmembrane Protein Claudin Subtype Expression and Distribution in Human Corneal and Conjunctival Epithelium
inferredcites →https://doi.org/10.1167/iovs.09-4933openalex-snapshot
Decorin Accumulation Contributes to the Stromal Opacities Found in Congenital Stromal Corneal Dystrophy
inferredcites →https://doi.org/10.1167/iovs.10-6486openalex-snapshot
Wnt/β-Catenin Signaling Regulates Proliferation of Human Cornea Epithelial Stem/Progenitor Cells
inferredcites →https://doi.org/10.1167/iovs.13-12089openalex-snapshot
Mice With a Targeted Disruption of Slc4a11 Model the Progressive Corneal Changes of Congenital Hereditary Endothelial Dystrophy
inferredcites →https://doi.org/10.1167/iovs.18-26018openalex-snapshot
Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea
inferredcites →https://doi.org/10.1167/iovs.19-27656openalex-snapshot
Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population
inferredcites →https://doi.org/10.1186/1471-213x-11-54openalex-snapshot
Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling
inferredcites →https://doi.org/10.1186/1750-1172-4-7openalex-snapshot
Corneal dystrophies
inferredcites →https://doi.org/10.1186/gb-2003-4-5-p3openalex-snapshot
DAVID: Database for Annotation, Visualization, and Integrated Discovery
inferredcites →https://doi.org/10.1186/s12881-015-0179-9openalex-snapshot
Case report: a novel KERA mutation associated with cornea plana and its predicted effect on protein function
inferredcites →https://doi.org/10.1242/bio.20123145openalex-snapshot
Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier
inferredcites →https://doi.org/10.1242/bio.20136023openalex-snapshot
A stem cell proliferation burst forms new layers of P63 expressing suprabasal cells during zebrafish postembryonic epidermal development
inferredcites →https://doi.org/10.1242/dev.040451openalex-snapshot
A directional Wnt/β-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina
inferredcites →https://doi.org/10.1242/dev.071191openalex-snapshot
ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation
inferredcites →https://doi.org/10.1242/dev.102426openalex-snapshot
A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis
inferredcites →https://doi.org/10.1242/dev.133058openalex-snapshot
Understanding development and stem cells using single cell-based analyses of gene expression
inferredcites →https://doi.org/10.1242/dev.174177openalex-snapshot
Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions
inferredcites →https://doi.org/10.1242/dev.32.3.783openalex-snapshot
Ontogeny and localization of the lens crystallins inXenopus laevislens regeneration
inferredcites →https://doi.org/10.1242/dev.80.1.289openalex-snapshot
Regional biosynthetic markers in the early amphibian embryo
inferredcites →https://doi.org/10.1242/dmm.006494openalex-snapshot
Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease
inferredcites →https://doi.org/10.1242/jcs.111.19.2867openalex-snapshot
Strategies of epithelial repair: Modulation of stem cell and transit amplifying cell proliferation
inferredcites →https://doi.org/10.1242/jcs.198119openalex-snapshot
Corneal epithelial stem cells and their niche at a glance
inferredcites →https://doi.org/10.1369/jhc.2008.952390openalex-snapshot
Distribution of Label-retaining Cells in the Limbal Epithelium of a Mouse Eye
inferredcites →https://doi.org/10.1371/journal.pone.0064244openalex-snapshot
Transcriptional Dissection of Human Limbal Niche Compartments by Massive Parallel Sequencing
inferredcites →https://doi.org/10.1371/journal.pone.0095037openalex-snapshot
Posterior Amorphous Corneal Dystrophy Is Associated with a Deletion of Small Leucine-rich Proteoglycans on Chromosome 12
inferredcites →https://doi.org/10.1371/journal.pone.0113810openalex-snapshot
Diurnal Variation of Tight Junction Integrity Associates Inversely with Matrix Metalloproteinase Expression in Xenopus laevis Corneal Epithelium: Implications for Circadian Regulation of Homeostatic Surface Cell Desquamation
inferredcites →https://doi.org/10.1371/journal.pone.0117581openalex-snapshot
Discovery of Molecular Markers to Discriminate Corneal Endothelial Cells in the Human Body
inferredcites →https://doi.org/10.15252/msb.20178046openalex-snapshot
Using single‐cell genomics to understand developmental processes and cell fate decisions
inferredcites →https://doi.org/10.1634/stemcells.22-3-355openalex-snapshot
Characterization of Putative Stem Cell Phenotype in Human Limbal Epithelia
inferredcites →https://doi.org/10.2307/1439568openalex-snapshot
Normal Table of Xenopus Laevis (Daudin)
inferredcites →https://doi.org/10.3389/fphys.2019.00154openalex-snapshot
Xenbase: Facilitating the Use of Xenopus to Model Human Disease
inferredcites →https://doi.org/10.3390/ijms19071982openalex-snapshot
An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells
inferredcites →https://doi.org/10.4252/wjsc.v6.i4.391openalex-snapshot
Limbal stem cells: Central concepts of corneal epithelial homeostasis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.jtos.2021.04.010openalex-snapshot
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege
inferred← citeshttps://doi.org/10.1038/s41467-022-31949-2openalex-snapshot
Cell landscape of larval and adult Xenopus laevis at single-cell resolution
inferred← citeshttps://doi.org/10.64898/2026.05.03.722558openalex-snapshot
WITHDRAWN: A Post-Surgical Retinal Progenitor Cell Niche is the Primary Source of Embryonic Eye Regrowth in Xenopus laevis
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