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L-threonine mediated DAF-16/HSF-1 activation inhibits ferroptosis and increases healthspan
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Quantification of Glutathione in Caenorhabditis elegans
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Small Molecule from Natural Phytochemical Mimics Dietary Restriction by Modulating FoxO3a and Metabolic Reprogramming
inferredcites →https://doi.org/10.1016/j.cell.2015.02.020openalex-snapshot
Promoting Health and Longevity through Diet: From Model Organisms to Humans
inferredcites →https://doi.org/10.1016/j.celrep.2017.11.108openalex-snapshot
The Sexual Dimorphism of Dietary Restriction Responsiveness in Caenorhabditis elegans
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Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice
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Metabolic Flexibility in Health and Disease
inferredcites →https://doi.org/10.1016/j.cmet.2018.02.004openalex-snapshot
Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis
inferredcites →https://doi.org/10.1016/j.cmet.2019.02.013openalex-snapshot
Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity
inferredcites →https://doi.org/10.1016/j.cmet.2020.04.018openalex-snapshot
Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice
inferredcites →https://doi.org/10.1016/j.cmet.2021.08.018openalex-snapshot
Evaluating the beneficial effects of dietary restrictions: A framework for precision nutrigeroscience
inferredcites →https://doi.org/10.1016/j.devcel.2020.06.019openalex-snapshot
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells
inferredcites →https://doi.org/10.1016/j.devcel.2021.03.034openalex-snapshot
Lipid metabolism and lipid signals in aging and longevity
inferredcites →https://doi.org/10.1016/j.ebiom.2019.04.005openalex-snapshot
The impact of dietary protein intake on longevity and metabolic health
inferredcites →https://doi.org/10.1016/j.exger.2018.10.003openalex-snapshot
Identification of key pathways and metabolic fingerprints of longevity in C. elegans
inferredcites →https://doi.org/10.1016/j.jaci.2020.07.035openalex-snapshot
Fasting, dietary restriction, and immunosenescence
inferredcites →https://doi.org/10.1016/j.molmet.2019.03.008openalex-snapshot
Ferritin regulates organismal energy balance and thermogenesis
inferredcites →https://doi.org/10.1016/j.nut.2018.07.114openalex-snapshot
l-Threonine improves intestinal mucin synthesis and immune function of intrauterine growth–retarded weanling piglets
inferredcites →https://doi.org/10.1016/s0895-3988(09)60004-0openalex-snapshot
Phenotypic and Behavioral Defects Induced by Iron Exposure Can Be Transferred to Progeny in Caenorhabditis elegans
inferredcites →https://doi.org/10.1017/s1751731112000833openalex-snapshot
Effect of threonine on immunity and reproductive performance of male mice infected with pseudorabies virus
inferredcites →https://doi.org/10.1021/acs.jafc.0c01023openalex-snapshot
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice
inferredcites →https://doi.org/10.1021/tx015526ropenalex-snapshot
Aerobic Oxidation of Aminoacetone, a Threonine Catabolite: Iron Catalysis and Coupled Iron Release from Ferritin
inferredcites →https://doi.org/10.1038/msb.2012.74openalex-snapshot
Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
inferredcites →https://doi.org/10.1038/nature13264openalex-snapshot
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
inferredcites →https://doi.org/10.1038/nbt.3122openalex-snapshot
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
inferredcites →https://doi.org/10.1038/ncomms10043openalex-snapshot
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing
inferredcites →https://doi.org/10.1038/ncomms3192openalex-snapshot
Metformin improves healthspan and lifespan in mice
inferredcites →https://doi.org/10.1038/ncomms9332openalex-snapshot
Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan
inferredcites →https://doi.org/10.1038/nm.4132openalex-snapshot
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
inferredcites →https://doi.org/10.1038/nprot.2016.095openalex-snapshot
Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
inferredcites →https://doi.org/10.1038/s41467-020-14324-xopenalex-snapshot
Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
inferredcites →https://doi.org/10.1038/s41467-020-18696-yopenalex-snapshot
Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila
inferredcites →https://doi.org/10.1038/s41580-021-00411-4openalex-snapshot
Molecular mechanisms of dietary restriction promoting health and longevity
inferredcites →https://doi.org/10.1038/s41593-021-00862-0openalex-snapshot
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
inferredcites →https://doi.org/10.1038/s42255-019-0059-2openalex-snapshot
Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control
inferredcites →https://doi.org/10.1038/s42255-019-0161-5openalex-snapshot
NAD+ homeostasis in health and disease
inferredcites →https://doi.org/10.1039/c3mb25539eopenalex-snapshot
A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks
inferredcites →https://doi.org/10.1039/c5sc00233hopenalex-snapshot
Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans
inferredcites →https://doi.org/10.1074/jbc.m110.216283openalex-snapshot
l-Threonine Regulates G1/S Phase Transition of Mouse Embryonic Stem Cells via PI3K/Akt, MAPKs, and mTORC Pathways
inferredcites →https://doi.org/10.1074/jbc.m210333200openalex-snapshot
Cytosolic Aconitase and Ferritin Are Regulated by Iron inCaenorhabditis elegans
inferredcites →https://doi.org/10.1074/jbc.m707043200openalex-snapshot
An Iron Enhancer Element in the FTN-1 Gene Directs Iron-dependent Expression in Caenorhabditis elegans Intestine
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/jn/nxy162openalex-snapshot
'Endogenous Amino Acid Losses from the Gastrointestinal Tract of the Adult Human—A Quantitative Model
inferredcites →https://doi.org/10.1097/mco.0000000000000007openalex-snapshot
Threonine metabolism and embryonic stem cell self-renewal
inferredcites →https://doi.org/10.1111/acel.12953openalex-snapshot
Glycine supplementation extends lifespan of male and female mice
inferredcites →https://doi.org/10.1111/all.14657openalex-snapshot
Risk factors for severe and critically ill COVID‐19 patients: A review
inferredcites →https://doi.org/10.1126/science.1226603openalex-snapshot
Influence of Threonine Metabolism on S -Adenosylmethionine and Histone Methylation
inferredcites →https://doi.org/10.1126/scitranslmed.aai8700openalex-snapshot
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
inferredcites →https://doi.org/10.1182/blood-2017-02-768580openalex-snapshot
Ferritin is secreted via 2 distinct nonclassical vesicular pathways
inferredcites →https://doi.org/10.1186/1471-2199-9-9openalex-snapshot
Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans
inferredcites →https://doi.org/10.1186/s12863-015-0167-2openalex-snapshot
Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pbio.2006203openalex-snapshot
Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
inferredcites →https://doi.org/10.1371/journal.pgen.1007633openalex-snapshot
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
inferredcites →https://doi.org/10.1534/genetics.118.301307openalex-snapshot
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
inferredcites →https://doi.org/10.2741/e322openalex-snapshot
Specific roles of threonine in intestinal mucosal integrity and barrier function
inferredcites →https://doi.org/10.3389/fcell.2021.672545openalex-snapshot
Interkingdom Comparison of Threonine Metabolism for Stem Cell Maintenance in Plants and Animals
inferredcites →https://doi.org/10.3390/metabo11020125openalex-snapshot
Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death
inferredcites →https://doi.org/10.3390/nu13082592openalex-snapshot
Physiological Functions of Threonine in Animals: Beyond Nutrition Metabolism
inferredcites →https://doi.org/10.7554/elife.56580openalex-snapshot
Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans
inferredcites →https://doi.org/10.7554/elife.57849openalex-snapshot
Whole-genome sequencing analysis of semi-supercentenarians
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