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Nrf2 promotes thyroid development and hormone synthesis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/aja.1002030302openalex-snapshot
Stages of embryonic development of the zebrafish
inferredcites →https://doi.org/10.1002/cphy.c150027openalex-snapshot
Hypothalamus‐Pituitary‐Thyroid Axis
inferredcites →https://doi.org/10.1002/dvdy.20831openalex-snapshot
Analysis of origin and growth of the thyroid gland in zebrafish
inferredcites →https://doi.org/10.1002/dvdy.21343openalex-snapshot
The Tol2kit: A multisite gateway‐based construction kit for Tol2 transposon transgenesis constructs
inferredcites →https://doi.org/10.1002/dvdy.21354openalex-snapshot
Gateway compatible vectors for analysis of gene function in the zebrafish
inferredcites →https://doi.org/10.1007/978-1-4939-6949-4_7openalex-snapshot
Generation of Functional Thyroid Tissue Using 3D-Based Culture of Embryonic Stem Cells
inferredcites →https://doi.org/10.1007/s00018-003-3206-5openalex-snapshot
Diversity of structures and properties among catalases
inferredcites →https://doi.org/10.1007/s00018-016-2223-0openalex-snapshot
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
inferredcites →https://doi.org/10.1007/s00427-002-0279-3openalex-snapshot
Phenylthiourea disrupts thyroid function in developing zebrafish
inferredcites →https://doi.org/10.1016/0303-7207(89)90186-xopenalex-snapshot
Thyroglobulin gene expression as a differentiation marker in primary cultures of calf thyroid cells
inferredcites →https://doi.org/10.1016/1043-2760(92)90086-gopenalex-snapshot
Control of thyroid cell proliferation and goitrogenesis
inferredcites →https://doi.org/10.1016/j.bbrc.2014.01.056openalex-snapshot
Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process
inferredcites →https://doi.org/10.1016/j.bcp.2008.07.017openalex-snapshot
Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis
inferredcites →https://doi.org/10.1016/j.beem.2018.05.002openalex-snapshot
Genetics and management of congenital hypothyroidism
inferredcites →https://doi.org/10.1016/j.ccr.2012.05.016openalex-snapshot
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
inferredcites →https://doi.org/10.1016/j.cell.2016.02.014openalex-snapshot
Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate
inferredcites →https://doi.org/10.1016/j.expneurol.2012.07.019openalex-snapshot
Maternal thyroid hormone deficiency affects the fetal neocorticogenesis by reducing the proliferating pool, rate of neurogenesis and indirect neurogenesis
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.09.010openalex-snapshot
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
inferredcites →https://doi.org/10.1016/j.mce.2004.06.006openalex-snapshot
The control of thyroid-specific gene expression: what exactly have we learned as yet?
inferredcites →https://doi.org/10.1016/j.mce.2005.11.030openalex-snapshot
Thyroid hormone action at the cellular, genomic and target gene levels
inferredcites →https://doi.org/10.1016/j.mce.2009.05.011openalex-snapshot
Thyroid gland development and function in the zebrafish model
inferredcites →https://doi.org/10.1016/j.mce.2017.01.038openalex-snapshot
Thyroid hormone biosynthesis and release
inferredcites →https://doi.org/10.1016/j.mce.2019.110635openalex-snapshot
Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound
inferredcites →https://doi.org/10.1016/j.mce.2021.111313openalex-snapshot
Shaping the thyroid: From peninsula to de novo lumen formation
inferredcites →https://doi.org/10.1016/j.molmed.2019.09.007openalex-snapshot
Nrf2: Redox and Metabolic Regulator of Stem Cell State and Function
inferredcites →https://doi.org/10.1016/j.neuroscience.2015.09.070openalex-snapshot
Influence of maternal thyroid hormones during gestation on fetal brain development
inferredcites →https://doi.org/10.1016/j.pharmthera.2015.11.003openalex-snapshot
Nrf2–ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
inferredcites →https://doi.org/10.1016/j.taap.2018.09.013openalex-snapshot
Genome-wide identification and analysis of Nrf2 binding sites – Antioxidant response elements in zebrafish
inferredcites →https://doi.org/10.1016/j.ydbio.2012.09.011openalex-snapshot
Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development
inferredcites →https://doi.org/10.1016/s0021-9258(18)89450-9openalex-snapshot
Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone.
inferredcites →https://doi.org/10.1016/s0021-9258(18)99004-6openalex-snapshot
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
inferredcites →https://doi.org/10.1016/s0091-679x(04)77011-9openalex-snapshot
Transgenesis and Gene Trap Methods in Zebrafish by Using the Tol2 Transposable Element
inferredcites →https://doi.org/10.1016/s0955-0674(97)80068-3openalex-snapshot
AP-1 function and regulation
inferredcites →https://doi.org/10.1021/es202248hopenalex-snapshot
Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis
inferredcites →https://doi.org/10.1038/nature11525openalex-snapshot
Generation of functional thyroid from embryonic stem cells
inferredcites →https://doi.org/10.1038/ncb2699openalex-snapshot
Nrf2 regulates haematopoietic stem cell function
inferredcites →https://doi.org/10.1038/s41598-018-24036-4openalex-snapshot
A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function
inferredcites →https://doi.org/10.1046/j.1432-0436.2002.700104.xopenalex-snapshot
Thyroid hormones are important for embryonic to larval transitory phase in zebrafish
inferredcites →https://doi.org/10.1046/j.1523-1755.2001.00939.xopenalex-snapshot
Nrf2-deficient female mice develop lupus-like autoimmune nephritis11See Editorial by Byrd and Thomas, p. 1606.
inferredcites →https://doi.org/10.1056/nejm200102153440707openalex-snapshot
Thyroid Hormone and the Cardiovascular System
inferredcites →https://doi.org/10.1073/pnas.242322099openalex-snapshot
Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice
inferredcites →https://doi.org/10.1073/pnas.242328999openalex-snapshot
Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland
inferredcites →https://doi.org/10.1073/pnas.81.19.5941openalex-snapshot
Thyrotropin controls transcription of the thyroglobulin gene.
inferredcites →https://doi.org/10.1074/jbc.270.28.16483openalex-snapshot
The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases
inferredcites →https://doi.org/10.1074/jbc.m111.260125openalex-snapshot
Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2)
inferredcites →https://doi.org/10.1074/jbc.m403061200openalex-snapshot
Redox-regulated Turnover of Nrf2 Is Determined by at Least Two Separate Protein Domains, the Redox-sensitive Neh2 Degron and the Redox-insensitive Neh6 Degron
inferredcites →https://doi.org/10.1080/10715769900300851openalex-snapshot
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
inferredcites →https://doi.org/10.1089/thy.2007.0266openalex-snapshot
Thyroid Hormone as a Determinant of Energy Expenditure and the Basal Metabolic Rate
inferredcites →https://doi.org/10.1089/thy.2018.0018openalex-snapshot
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland
inferredcites →https://doi.org/10.1089/zeb.2014.1047openalex-snapshot
A Streamlined CRISPR Pipeline to Reliably Generate Zebrafish Frameshifting Alleles
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/bioinformatics/btu638openalex-snapshot
HTSeq—a Python framework to work with high-throughput sequencing data
inferredcites →https://doi.org/10.1093/nar/gkq212openalex-snapshot
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
inferredcites →https://doi.org/10.1093/nar/gkv1176openalex-snapshot
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles
inferredcites →https://doi.org/10.1093/nar/gkw1069openalex-snapshot
The eukaryotic promoter database in its 30th year: focus on non-vertebrate organisms
inferredcites →https://doi.org/10.1101/gr.191452.115openalex-snapshot
Sequence determinants of improved CRISPR sgRNA design
inferredcites →https://doi.org/10.1128/mcb.00049-17openalex-snapshot
Multitiered and Cooperative Surveillance of Mitochondrial Phosphatidylserine Decarboxylase 1
inferredcites →https://doi.org/10.1128/mcb.00389-16openalex-snapshot
Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells
inferredcites →https://doi.org/10.1128/mcb.00481-12openalex-snapshot
Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress
inferredcites →https://doi.org/10.1128/mcb.23.23.8786-8794.2003openalex-snapshot
Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway
inferredcites →https://doi.org/10.1146/annurev-pharmtox-011112-140320openalex-snapshot
Role of Nrf2 in Oxidative Stress and Toxicity
inferredcites →https://doi.org/10.1152/physrev.00023.2017openalex-snapshot
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
inferredcites →https://doi.org/10.1152/physrev.00030.2013openalex-snapshot
Thyroid Hormone Regulation of Metabolism
inferredcites →https://doi.org/10.1155/2015/283492openalex-snapshot
Low Growth Hormone Levels in Short-Stature Children with Pituitary Hyperplasia Secondary to Primary Hypothyroidism
inferredcites →https://doi.org/10.1186/jbiol61openalex-snapshot
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
inferredcites →https://doi.org/10.1186/s12859-018-2201-7openalex-snapshot
Recommending plant taxa for supporting on-site species identification
inferredcites →https://doi.org/10.1210/edrv-13-3-596openalex-snapshot
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
inferredcites →https://doi.org/10.1210/en.2008-1795openalex-snapshot
Thyrotropin-Releasing Hormone and the Thyroid Hormone Feedback Mechanism
inferredcites →https://doi.org/10.1210/er.2003-0033openalex-snapshot
Thyroid Hormone Action in the Heart
inferredcites →https://doi.org/10.1210/er.2015-1090openalex-snapshot
Thyroglobulin From Molecular and Cellular Biology to Clinical Endocrinology
inferredcites →https://doi.org/10.1210/jc.2010-2814openalex-snapshot
Fetal Thyroid Hormone Level at Birth Is Associated with Fetal Growth
inferredcites →https://doi.org/10.1210/me.2011-0046openalex-snapshot
TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish
inferredcites →https://doi.org/10.1242/dev.134171openalex-snapshot
Thyroid follicle development requires Smad1/Smad5- and endothelial-dependent basement membrane assembly
inferredcites →https://doi.org/10.1242/dev.146829openalex-snapshot
A branching morphogenesis program governs embryonic growth of the thyroid gland
inferredcites →https://doi.org/10.1371/journal.pone.0016163openalex-snapshot
E2F1 Regulates Cellular Growth by mTORC1 Signaling
inferredcites →https://doi.org/10.1371/journal.pone.0131080openalex-snapshot
Biodiversity on the Rocks: Macrofauna Inhabiting Authigenic Carbonate at Costa Rica Methane Seeps
inferredcites →https://doi.org/10.1530/erc-18-0476openalex-snapshot
Oxidative stress in thyroid carcinomas: biological and clinical significance
inferredcites →https://doi.org/10.1677/joe-08-0470openalex-snapshot
Minimal oxidative load: a prerequisite for thyroid cell function
inferredcites →https://doi.org/10.2353/ajpath.2006.051113openalex-snapshot
Multiorgan Autoimmune Inflammation, Enhanced Lymphoproliferation, and Impaired Homeostasis of Reactive Oxygen Species in Mice Lacking the Antioxidant-Activated Transcription Factor Nrf2
inferredcites →https://doi.org/10.3389/fendo.2019.00383openalex-snapshot
Teleost Metamorphosis: The Role of Thyroid Hormone
inferredcites →https://doi.org/10.3389/fendo.2019.00510openalex-snapshot
Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer
inferredcites →https://doi.org/10.3389/fendo.2021.655862openalex-snapshot
Modelling of Epithelial Growth, Fission and Lumen Formation During Embryonic Thyroid Development: A Combination of Computational and Experimental Approaches
inferredcites →https://doi.org/10.3390/antiox9090884openalex-snapshot
The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System
inferredcites →https://doi.org/10.3390/ijms20123040openalex-snapshot
Evolution Shapes the Gene Expression Response to Oxidative Stress
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inferred← citeshttps://doi.org/10.1038/s41574-026-01249-6openalex-snapshot
Human thyroid organoids: tools for understanding thyroid diseases and development
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