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A Trypanosoma cruzi Antigen and Epitope Atlas: deep characterization of antibody specificities in Chagas Disease patients across the Americas

https://doi.org/10.1101/2022.08.19.504544

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Antibody Epitope Mapping Using SPOT™ Peptide Arrays

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Strategies for epitope analysis using peptide synthesis

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Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs

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Sequence of the gene for a Trypanosoma cruzi protein antigenic during the chronic phase of human Chagas disease

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Chagas Disease Diagnostic Applications

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Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity

inferredcites →https://doi.org/10.1016/j.cmi.2016.06.001openalex-snapshot

Serodiscordance in chronic Chagas disease diagnosis: a real problem in non-endemic countries

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Re-imagining the future of diagnosis of Neglected Tropical Diseases

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Putting Infection Dynamics at the Heart of Chagas Disease

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Parasite polyclonal activators: new targets for vaccination approaches?

inferredcites →https://doi.org/10.1016/s0140-6736(17)31612-4openalex-snapshot

Chagas disease

inferredcites →https://doi.org/10.1016/s1471-4922(01)01897-9openalex-snapshot

Chagas disease: recombinant Trypanosoma cruzi antigens for serological diagnosis

inferredcites →https://doi.org/10.1016/s1473-3099(20)30729-5openalex-snapshot

Prediction of parasitological cure in children infected with Trypanosoma cruzi using a novel multiplex serological approach: an observational, retrospective cohort study

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Single Amino Acid Substitution in the Vicinity of a Receptor-Binding Domain Changes Protein–Peptide Binding Affinity

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Individually addressable parallel peptide synthesis on microchips

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Scalable high-density peptide arrays for comprehensive health monitoring

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Pathogen manipulation of B cells: the best defence is a good offence

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A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin

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Antibody diversification by somatic mutation: from Burnet onwards

inferredcites →https://doi.org/10.1074/mcp.m112.020800openalex-snapshot

High-resolution Mapping of Linear Antibody Epitopes Using Ultrahigh-density Peptide Microarrays

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Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants

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Parasite Persistence Correlates with Disease Severity and Localization in Chronic Chagas' Disease

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Diagnostics in a digital age: an opportunity to strengthen health systems and improve health outcomes

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UpSet: Visualization of Intersecting Sets

inferredcites →https://doi.org/10.1111/j.1365-2567.2010.03347.xopenalex-snapshot

Trypanosoma cruzi infection induces a massive extrafollicular and follicular splenic B-cell response which is a high source of non-parasite-specific antibodies

inferredcites →https://doi.org/10.1111/pim.12786openalex-snapshot

Host‐parasite dynamics in Chagas disease from systemic to hyper‐local scales

inferredcites →https://doi.org/10.1126/science.1112631openalex-snapshot

The Genome Sequence of Trypanosoma cruzi , Etiologic Agent of Chagas Disease

inferredcites →https://doi.org/10.1128/jcm.00142-16openalex-snapshot

Serological Diagnosis of Chronic Chagas Disease: Is It Time for a Change?

inferredcites →https://doi.org/10.1128/mbio.01242-20openalex-snapshot

In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution

inferredcites →https://doi.org/10.1146/annurev.biochem.76.061705.090740openalex-snapshot

Molecular Mechanisms of Antibody Somatic Hypermutation

inferredcites →https://doi.org/10.1158/0008-5472.can-18-1536openalex-snapshot

Whole Genome–Derived Tiled Peptide Arrays Detect Prediagnostic Autoantibody Signatures in Non–Small-Cell Lung Cancer

inferredcites →https://doi.org/10.1161/cir.0000000000000599openalex-snapshot

Chagas Cardiomyopathy: An Update of Current Clinical Knowledge and Management: A Scientific Statement From the American Heart Association

inferredcites →https://doi.org/10.1186/1471-2164-13-531openalex-snapshot

Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei

inferredcites →https://doi.org/10.1186/1745-7580-2-2openalex-snapshot

Improved method for predicting linear B-cell epitopes.

inferredcites →https://doi.org/10.1186/s13071-015-1072-2openalex-snapshot

Highly discordant serology against Trypanosoma cruzi in central Veracruz, Mexico: role of the antigen used for diagnostic

inferredcites →https://doi.org/10.1371/journal.pntd.0004596openalex-snapshot

Development of a Novel Multiplex Immunoassay Multi-cruzi for the Serological Confirmation of Chagas Disease

inferredcites →https://doi.org/10.1371/journal.pntd.0004792openalex-snapshot

Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Typing Units (DTUs): Attempt at an Inventory

inferredcites →https://doi.org/10.1371/journal.pntd.0005330openalex-snapshot

Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome

inferredcites →https://doi.org/10.1371/journal.pone.0023042openalex-snapshot

Genome Size, Karyotype Polymorphism and Chromosomal Evolution in Trypanosoma cruzi

inferredcites →https://doi.org/10.1371/journal.pone.0068902openalex-snapshot

Identification and Mapping of Linear Antibody Epitopes in Human Serum Albumin Using High-Density Peptide Arrays

inferredcites →https://doi.org/10.1371/journal.pone.0248666openalex-snapshot

Scoping review of the applications of peptide microarrays on the fight against human infections

inferredcites →https://doi.org/10.1385/0-89603-375-9:149openalex-snapshot

SPOT Synthesis: Epitope Analysis with Arrays of Synthetic Peptides Prepared on Cellulose Membranes

inferredcites →https://doi.org/10.3389/fimmu.2021.702552openalex-snapshot

APRANK: Computational Prioritization of Antigenic Proteins and Peptides From Complete Pathogen Proteomes

inferredcites →https://doi.org/10.4049/jimmunol.1101823openalex-snapshot

Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence

inferredcites →https://doi.org/10.4049/jimmunol.2000224openalex-snapshot

HLA Class II Specificity Assessed by High-Density Peptide Microarray Interactions

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