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Mechanisms underlying divergent relationships between Ca 2+ and YAP/TAZ signaling
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Emerging themes and unifying concepts underlying cell behavior regulation by the pericellular space
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GPER stabilizes F-actin cytoskeleton and activates TAZ via PLCβ-PKC and Rho/ROCK-LIMK-Cofilin pathway
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Dimensionality and spreading influence MSC YAP/TAZ signaling in hydrogel environments
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The Delicate Bistability of CaMKII
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Systems Modeling of Ca2+ Homeostasis and Mobilization in Platelets Mediated by IP3 and Store-Operated Ca2+ Entry
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A Computational Model of YAP/TAZ Mechanosensing
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Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
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ET-1-induced growth promoting responses involving ERK1/2 and PKB signaling and Egr-1 expression are mediated by Ca2+/CaM-dependent protein kinase-II in vascular smooth muscle cells
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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
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Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores
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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
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Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin
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Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling
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Forcing Entry into the Nucleus
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A multi-criteria trajectory-based parameter sampling strategy for the screening method of elementary effects
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YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
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Modeling the impact of store-operated Ca2+ entry on intracellular Ca2+ oscillations
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Thapsigargin-induced activation of Ca2+-CaMKII-ERK in brainstem contributes to substance P release and induction of emesis in the least shrew
inferredcites →https://doi.org/10.1016/j.semcdb.2012.05.004openalex-snapshot
The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
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Bistability in the Ca2+/Calmodulin-Dependent Protein Kinase-Phosphatase System
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A Mathematical Model Predicts that Calreticulin Interacts with the Endoplasmic Reticulum Ca2+-ATPase
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Thapsigargin activates a calcium influx pathway in the unfertilized mouse egg and suppresses repetitive calcium transients in the fertilized egg.
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MST1/MST2 Protein Kinases: Regulation and Physiologic Roles
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Substrate Stiffness, Cell Anisotropy, and Cell–Cell Contact Contribute to Enhanced Structural and Calcium Handling Properties of Human Embryonic Stem Cell-Derived Cardiomyocytes
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From Mechanical Force to RhoA Activation
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Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation
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A crucial role of WW45 in developing epithelial tissues in the mouse
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Recurrent design patterns in the feedback regulation of the mammalian signalling network
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Role of YAP/TAZ in mechanotransduction
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Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling
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The interplay between cell signalling and mechanics in developmental processes
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PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells
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mDia1 senses both force and torque during F-actin filament polymerization
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Calcium sensing by the STIM1 ER-luminal domain
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YAP-independent mechanotransduction drives breast cancer progression
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GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics
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Concerted localization-resets precede YAP-dependent transcription
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YAP/TAZ upstream signals and downstream responses
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Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling
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Single-cell study of the extracellular matrix effect on cell growth by in situ imaging of gene expression
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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
inferredcites →https://doi.org/10.1042/bj3000665openalex-snapshot
Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane
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Activation mechanisms of the Hippo kinase signaling cascade
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Angiotensin II Type 2 Receptor‐Mediated Stimulation of Protein Phosphatase 2A in Rat Hypothalamic/Brainstem Neuronal Cocultures
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Virtual Cell modelling and simulation software environment
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Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks
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Paradoxical signaling regulates structural plasticity in dendritic spines
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A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration.
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Cell signaling pathways as control modules: Complexity for simplicity?
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YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing
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Ionomycin-activated Calpain Triggers Apoptosis
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Role of RhoA, mDia, and ROCK in Cell Shape-dependent Control of the Skp2-p27 Pathway and the G1/S Transition
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Tumor Suppressor LATS1 Is a Negative Regulator of Oncogene YAP
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Control of cellular responses to mechanical cues through YAP/TAZ regulation
inferredcites →https://doi.org/10.1080/21541248.2018.1435986openalex-snapshot
Reciprocal regulation of YAP/TAZ by the Hippo pathway and the Small GTPase pathway
inferredcites →https://doi.org/10.1080/21688370.2016.1187326openalex-snapshot
Control of cell mechanics by RhoA and calcium fluxes during epithelial scattering
inferredcites →https://doi.org/10.1088/1478-3975/4/4/009openalex-snapshot
The variety of cytosolic calcium responses and possible roles of PLC and PKC
inferredcites →https://doi.org/10.1091/mbc.e15-05-0265openalex-snapshot
Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling
inferredcites →https://doi.org/10.1097/maj.0b013e318244745bopenalex-snapshot
Regulation of Cofilin Activity by CaMKII and Calcineurin
inferredcites →https://doi.org/10.1098/rsta.2006.1758openalex-snapshot
Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca 2+ handling and interval–force relations: a modelling study
inferredcites →https://doi.org/10.1101/cshperspect.a005934openalex-snapshot
Signaling Networks: Information Flow, Computation, and Decision Making
inferredcites →https://doi.org/10.1101/gad.262816.115openalex-snapshot
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
inferredcites →https://doi.org/10.1101/gad.274027.115openalex-snapshot
Mechanisms of Hippo pathway regulation
inferredcites →https://doi.org/10.1126/science.1091325openalex-snapshot
Localized Stabilization of Microtubules by Integrin- and FAK-Facilitated Rho Signaling
inferredcites →https://doi.org/10.1126/science.1240104openalex-snapshot
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
inferredcites →https://doi.org/10.1126/science.1986413openalex-snapshot
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
inferredcites →https://doi.org/10.1126/science.283.5400.381openalex-snapshot
Emergent Properties of Networks of Biological Signaling Pathways
inferredcites →https://doi.org/10.1128/mcb.23.24.9389-9404.2003openalex-snapshot
Caveolin-1 Maintains Activated Akt in Prostate CancerCells through Scaffolding Domain Binding Site Interactions with andInhibition of Serine/Threonine Protein Phosphatases PP1 andPP2A
inferredcites →https://doi.org/10.1139/cjpp-2021-0033openalex-snapshot
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice
inferredcites →https://doi.org/10.1146/annurev-biochem-013118-111829openalex-snapshot
The Hippo Pathway: Biology and Pathophysiology
inferredcites →https://doi.org/10.1146/annurev.biophys.29.1.545openalex-snapshot
Molecular Mechanisms Controlling Actin Filament Dynamics in Nonmuscle Cells
inferredcites →https://doi.org/10.1152/ajpcell.00187.2016openalex-snapshot
TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation
inferredcites →https://doi.org/10.1152/ajpcell.2001.281.4.c1165openalex-snapshot
Essential role for extracellular Ca2+ in JNK activation by mechanical stretch in bladder smooth muscle cells
inferredcites →https://doi.org/10.1152/ajpheart.00571.2004openalex-snapshot
Angiotensin II-induced Akt activation is mediated by metabolites of arachidonic acid generated by CaMKII-stimulated Ca2+-dependent phospholipase A2
inferredcites →https://doi.org/10.1152/ajprenal.00139.2003openalex-snapshot
Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β1
inferredcites →https://doi.org/10.1152/physrev.00005.2014openalex-snapshot
The Biology of YAP/TAZ: Hippo Signaling and Beyond
inferredcites →https://doi.org/10.1152/physrev.00013.2019openalex-snapshot
Stiffness Sensing by Cells
inferredcites →https://doi.org/10.1158/1541-7786.mcr-19-0070openalex-snapshot
A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial–Mesenchymal Transition in Breast Cancer Cells
inferredcites →https://doi.org/10.1161/01.res.69.3.800openalex-snapshot
Angiotensin-induced desensitization of the phosphoinositide pathway in cardiac cells occurs at the level of the receptor.
inferredcites →https://doi.org/10.1161/01.res.73.3.424openalex-snapshot
Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers.
inferredcites →https://doi.org/10.1161/01.res.83.8.841openalex-snapshot
Calcium- and Protein Kinase C–Dependent Activation of the Tyrosine Kinase PYK2 by Angiotensin II in Vascular Smooth Muscle
inferredcites →https://doi.org/10.1161/atvbaha.109.190892openalex-snapshot
PYK2/PDZ-RhoGEF Links Ca 2+ Signaling to RhoA
inferredcites →https://doi.org/10.1172/jci38857openalex-snapshot
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
inferredcites →https://doi.org/10.1186/2045-3701-3-33openalex-snapshot
Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators
inferredcites →https://doi.org/10.1186/s13045-022-01252-0openalex-snapshot
Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
inferredcites →https://doi.org/10.1186/s13287-018-0798-0openalex-snapshot
Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5
inferredcites →https://doi.org/10.1210/endo-128-1-231openalex-snapshot
Angiotensin-II-Induced Changes in Diacylglycerol Levels and Their Potential Role in Modulating the Steroidogenic Response*
inferredcites →https://doi.org/10.1242/jcs.210476openalex-snapshot
Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1
inferredcites →https://doi.org/10.1371/journal.pcbi.1009606openalex-snapshot
Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches
inferredcites →https://doi.org/10.1371/journal.pone.0147033openalex-snapshot
Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption
inferredcites →https://doi.org/10.1371/journal.pone.0181085openalex-snapshot
Engineered extracellular matrices with controlled mechanics modulate renal proximal tubular cell epithelialization
inferredcites →https://doi.org/10.1523/jneurosci.2348-08.2008openalex-snapshot
Coupled Phosphatase and Kinase Switches Produce the Tristability Required for Long-Term Potentiation and Long-Term Depression
inferredcites →https://doi.org/10.15252/embr.202050642openalex-snapshot
NEDD4L‐mediated Merlin ubiquitination facilitates Hippo pathway activation
inferredcites →https://doi.org/10.1529/biophysj.103.035253openalex-snapshot
A Signal Transduction Pathway Model Prototype I: From Agonist to Cellular Endpoint
inferredcites →https://doi.org/10.1529/biophysj.106.097469openalex-snapshot
A Kinetic Model for Calcium Dynamics in RAW 264.7 Cells: 1. Mechanisms, Parameters, and Subpopulational Variability
inferredcites →https://doi.org/10.1529/biophysj.106.101386openalex-snapshot
Fibroblast Adaptation and Stiffness Matching to Soft Elastic Substrates
inferredcites →https://doi.org/10.1529/biophysj.107.110031openalex-snapshot
Modeling Hypertrophic IP3 Transients in the Cardiac Myocyte
inferredcites →https://doi.org/10.26508/lsa.201800171openalex-snapshot
LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state
inferredcites →https://doi.org/10.3389/fcell.2021.673599openalex-snapshot
Mechanoregulation of YAP and TAZ in Cellular Homeostasis and Disease Progression
inferredcites →https://doi.org/10.3389/fcell.2021.694828openalex-snapshot
Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation
inferredcites →https://doi.org/10.3389/fphar.2020.00968openalex-snapshot
Calcium Permeable Channels in Cancer Hallmarks
inferredcites →https://doi.org/10.3390/cancers12092391openalex-snapshot
Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entry
inferredcites →https://doi.org/10.3390/genes7080044openalex-snapshot
Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis
inferredcites →https://doi.org/10.4149/gpb_2017022openalex-snapshot
Ca2+-dependent calcineurin/NFAT signaling in β-adrenergic-induced cardiac hypertrophy
inferredcites →https://doi.org/10.4161/cam.5.2.14403openalex-snapshot
Dynamics of the Rho-family small GTPases in actin regulation and motility
inferredcites →https://doi.org/10.7554/elife.34176openalex-snapshot
Modulation of formin processivity by profilin and mechanical tension
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