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Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology

https://doi.org/10.1101/2023.09.08.556840

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells

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Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.actbio.2025.09.039openalex-snapshot

Transient receptor potential vanilloid 4 modulates substrate stiffness mechanosensing and transcellular pore formation in human Schlemm’s canal cells

inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116703openalex-snapshot

YAP in development and disease: Navigating the regulatory landscape from retina to brain

inferred← citeshttps://doi.org/10.1038/s41597-025-04528-5openalex-snapshot

Divergence in cellular markers observed in single-cell transcriptomics datasets between cultured primary trabecular meshwork cells and tissues

inferred← citeshttps://doi.org/10.1101/2024.04.26.591346openalex-snapshot

To be or not to be - Decoding the Trabecular Meshwork Cell Identity

inferred← citeshttps://doi.org/10.1101/2025.05.25.656000openalex-snapshot

TRPV4 modulates substrate stiffness mechanosensing and transcellular pore formation in human Schlemm’s canal cells

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